JP2005514456A5 - - Google Patents
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- Publication number
- JP2005514456A5 JP2005514456A5 JP2003559979A JP2003559979A JP2005514456A5 JP 2005514456 A5 JP2005514456 A5 JP 2005514456A5 JP 2003559979 A JP2003559979 A JP 2003559979A JP 2003559979 A JP2003559979 A JP 2003559979A JP 2005514456 A5 JP2005514456 A5 JP 2005514456A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- halogen
- nhc
- alkoxy
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910052736 halogen Inorganic materials 0.000 claims 7
- 150000002367 halogens Chemical class 0.000 claims 7
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 125000001072 heteroaryl group Chemical group 0.000 claims 4
- -1 nitro, hydroxy Chemical group 0.000 claims 4
- 125000003118 aryl group Chemical group 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 125000002619 bicyclic group Chemical group 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 125000002950 monocyclic group Chemical group 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 206010019280 Heart failures Diseases 0.000 claims 1
- 208000031226 Hyperlipidaemia Diseases 0.000 claims 1
- 102000023984 PPAR alpha Human genes 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 125000003710 aryl alkyl group Chemical group 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 claims 1
- 239000002502 liposome Substances 0.000 claims 1
- 108091008725 peroxisome proliferator-activated receptors alpha Proteins 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002RM000014A ITRM20020014A1 (it) | 2002-01-15 | 2002-01-15 | Derivati di acidi a-feniltiocarbossilici e a-fenilossicarbossilici utili per il trattamento di patologie che rispondono all'attivazione del |
| PCT/IT2003/000011 WO2003059875A2 (en) | 2002-01-15 | 2003-01-15 | DERIVATIVES OF α-PHENYLTHIOCARBOXYLIC AND α-PHENYLOXY-CARBOXYLIC ACIDS USEFUL FOR THE TREATMENT OF DISEASES RESPONDING TO PPARα ACTIVATION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005514456A JP2005514456A (ja) | 2005-05-19 |
| JP2005514456A5 true JP2005514456A5 (enExample) | 2006-07-13 |
Family
ID=11455954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003559979A Pending JP2005514456A (ja) | 2002-01-15 | 2003-01-15 | ＰＰＡＲα活性化に応答する疾患の治療に有用なα−フェニルチオカルボン酸およびα−フェニルオキシカルボン酸の誘導体 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20050054671A1 (enExample) |
| EP (1) | EP1474387B1 (enExample) |
| JP (1) | JP2005514456A (enExample) |
| KR (1) | KR100975961B1 (enExample) |
| CN (1) | CN100522940C (enExample) |
| AR (1) | AR038146A1 (enExample) |
| AT (1) | ATE489361T1 (enExample) |
| AU (1) | AU2003209679B2 (enExample) |
| BR (1) | BR0306824A (enExample) |
| CA (1) | CA2472223A1 (enExample) |
| DE (1) | DE60335083D1 (enExample) |
| IT (1) | ITRM20020014A1 (enExample) |
| MX (1) | MXPA04006803A (enExample) |
| PL (1) | PL372666A1 (enExample) |
| TW (1) | TW200305410A (enExample) |
| WO (1) | WO2003059875A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7553867B2 (en) | 2002-09-06 | 2009-06-30 | Takeda Pharmaceutical Company Limited | Furan or thiophene derivative and medicinal use thereof |
| ITRM20020629A1 (it) * | 2002-12-19 | 2004-06-20 | Sigma Tau Ind Farmaceuti | Uso di acidi alfa-feniltiocarbossilici e alfa-fenilossicarbossilici ad attivita' ipoglicemizzante e/o ipolipidemizzante. |
| DK1667964T3 (da) | 2003-09-19 | 2009-10-26 | Janssen Pharmaceutica Nv | 4-((Phenoxyalkyl)thio)-phenoxyeddikesyrer og analoger |
| CN1867546A (zh) * | 2003-10-28 | 2006-11-22 | 雷迪实验室有限公司 | 新颖化合物及其在药物中的用途、其制备方法以及含有它们的药物组合物 |
| US7902367B2 (en) | 2004-08-11 | 2011-03-08 | Kyorin Pharmaceutical Co., Ltd. | Cyclic amino benzoic acid derivative |
| MY147518A (en) * | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| FR2880886B1 (fr) * | 2005-01-14 | 2007-04-06 | Merck Sante Soc Par Actions Si | Derives de l'acide 6-phenylhex-5-enoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique |
| WO2006082495A1 (en) * | 2005-02-02 | 2006-08-10 | Ranbaxy Laboratories Limited | Peroxisome proliferator activated receptor modulators |
| FR2882359A1 (fr) * | 2005-02-24 | 2006-08-25 | Negma Lerads Soc Par Actions S | Derives activateurs de ppar, procede de preparation et application en therapeutique |
| WO2006101108A1 (ja) * | 2005-03-23 | 2006-09-28 | Kyorin Pharmaceutical Co., Ltd. | 新規環状アミノフェニルアルカン酸誘導体 |
| JO3006B1 (ar) | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
| PE20080188A1 (es) | 2006-04-18 | 2008-03-10 | Janssen Pharmaceutica Nv | Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol |
| WO2008014430A1 (en) | 2006-07-27 | 2008-01-31 | Emisphere Technologies, Inc. | Arylsulfanyl compounds and compositions for delivering active agents |
| JP5305818B2 (ja) * | 2008-10-03 | 2013-10-02 | キヤノン株式会社 | 生体情報取得装置 |
| JP5669889B2 (ja) * | 2013-06-27 | 2015-02-18 | キヤノン株式会社 | 生体情報取得装置 |
| CN106179111B (zh) * | 2016-07-16 | 2018-08-14 | 江南大学 | 一种由羧酸盐阴离子表面活性剂和二聚季铵盐形成的粘弹溶液 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1121722A (en) * | 1966-03-31 | 1968-07-31 | Ici Ltd | New carboxylic acid derivatives |
| US3663540A (en) * | 1970-06-19 | 1972-05-16 | R & L Molecular Research Ltd | 7 - (p-aminomethylphenylthio)acetamido-3 -(pyridiniummethyl)ceph - 3 - em - 4-carboxylate |
| US3965093A (en) * | 1971-09-24 | 1976-06-22 | E. R. Squibb & Sons, Inc. | 6-Arylthio penicillanic acid and derivatives thereof |
| GB1422679A (en) * | 1972-11-16 | 1976-01-28 | Funai Pharmaceutical Ind Ltd | Substituted phenoxy-a-methylpropionic acid derivatives and a process for producing the same |
| FR2285867A1 (fr) * | 1974-09-30 | 1976-04-23 | Lafon Labor | Derives du diphenylsulfoxyde |
| DE2861187D1 (en) * | 1977-07-07 | 1981-12-24 | Ciba Geigy Ag | Phenoxy-phenylsulfinyl-and-sulfonylalkanecarboxylic acid derivatives, method for their preparation and their use as herbicides and plant growth regulators. |
| JPH0311045A (ja) * | 1989-06-08 | 1991-01-18 | Hodogaya Chem Co Ltd | ベンズアミド誘導体 |
| JPH06234732A (ja) * | 1992-09-10 | 1994-08-23 | Banyu Pharmaceut Co Ltd | 置換アセトアミド誘導体 |
| FR2700166B1 (fr) * | 1993-01-07 | 1995-02-17 | Rhone Poulenc Rorer Sa | Dérivés de pyrrolidine, leur préparation et les médicaments les contenant. |
| JP3583529B2 (ja) * | 1995-12-04 | 2004-11-04 | 富士写真フイルム株式会社 | ハロゲン化銀感光材料 |
| EP0904079B1 (en) * | 1996-02-02 | 2004-03-24 | Merck & Co., Inc. | Antidiabetic agents |
| AU4050797A (en) | 1996-08-02 | 1998-02-25 | Ligand Pharmaceuticals Incorporated | Prevention or treatment of type 2 diabetes or cardiovascular disease with ppar modulators |
| US6197791B1 (en) * | 1997-02-27 | 2001-03-06 | American Cyanamid Company | N-hdroxy-2-(alkyl, aryl, or heteroaryl, sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors |
| US6294573B1 (en) * | 1997-08-06 | 2001-09-25 | Abbott Laboratories | Reverse hydroxamate inhibitors of matrix metalloproteinases |
| CA2335288A1 (en) * | 1998-06-22 | 1999-12-29 | F. Hoffmann-La Roche Ag | Propenyl cephalosporin derivatives |
| JP4618845B2 (ja) * | 1999-06-09 | 2011-01-26 | 杏林製薬株式会社 | ヒトペルオキシゾーム増殖薬活性化受容体（ＰＰＡＲ）αアゴニストとしての置換フェニルプロピオン酸誘導体 |
| DE19940415A1 (de) * | 1999-08-26 | 2001-03-08 | Friedrich Spener | Verzweigtkettige Fettsäuren als fettabbauende Wirkstoffe |
| US6525093B1 (en) * | 1999-11-08 | 2003-02-25 | Calyx Therapeutics Inc. | Compounds to treat diabetes and associated conditions |
| KR20020090211A (ko) * | 2000-01-28 | 2002-11-30 | 노보 노르디스크 에이/에스 | 알키닐 치환된 프로피온산 유도체 및 당뇨병 및 비만에대한 그것의 사용 |
| WO2001079150A1 (en) * | 2000-04-17 | 2001-10-25 | Novo Nordisk A/S | New compounds, their preparation and use |
| PT1285908E (pt) * | 2000-05-29 | 2008-12-04 | Kyorin Seiyaku Kk | Derivados do ácido fenilpropiónico substituídos |
| CA2420178A1 (en) * | 2000-08-23 | 2002-03-07 | Eli Lilly And Company | Oxazolyl-aryloxyacetic acid derivatives and their use as ppar agonists |
| GB0111523D0 (en) * | 2001-05-11 | 2001-07-04 | Glaxo Group Ltd | Chemical compounds |
-
2002
- 2002-01-15 IT IT2002RM000014A patent/ITRM20020014A1/it unknown
-
2003
- 2003-01-15 KR KR1020047010634A patent/KR100975961B1/ko not_active Expired - Fee Related
- 2003-01-15 MX MXPA04006803A patent/MXPA04006803A/es active IP Right Grant
- 2003-01-15 BR BR0306824-2A patent/BR0306824A/pt not_active IP Right Cessation
- 2003-01-15 JP JP2003559979A patent/JP2005514456A/ja active Pending
- 2003-01-15 AU AU2003209679A patent/AU2003209679B2/en not_active Ceased
- 2003-01-15 EP EP03729547A patent/EP1474387B1/en not_active Expired - Lifetime
- 2003-01-15 DE DE60335083T patent/DE60335083D1/de not_active Expired - Lifetime
- 2003-01-15 AR ARP030100103A patent/AR038146A1/es unknown
- 2003-01-15 CN CNB038022893A patent/CN100522940C/zh not_active Expired - Fee Related
- 2003-01-15 TW TW092101061A patent/TW200305410A/zh unknown
- 2003-01-15 WO PCT/IT2003/000011 patent/WO2003059875A2/en not_active Ceased
- 2003-01-15 US US10/501,472 patent/US20050054671A1/en not_active Abandoned
- 2003-01-15 PL PL03372666A patent/PL372666A1/xx unknown
- 2003-01-15 AT AT03729547T patent/ATE489361T1/de not_active IP Right Cessation
- 2003-01-15 CA CA002472223A patent/CA2472223A1/en not_active Abandoned
-
2007
- 2007-08-17 US US11/889,930 patent/US20080027098A1/en not_active Abandoned