JP2005506354A - 癌治療のためのオリゴアミン化合物およびその誘導体 - Google Patents

癌治療のためのオリゴアミン化合物およびその誘導体 Download PDF

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Publication number
JP2005506354A
JP2005506354A JP2003536196A JP2003536196A JP2005506354A JP 2005506354 A JP2005506354 A JP 2005506354A JP 2003536196 A JP2003536196 A JP 2003536196A JP 2003536196 A JP2003536196 A JP 2003536196A JP 2005506354 A JP2005506354 A JP 2005506354A
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compound
chohch
group
another embodiment
butyl
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JP2005506354A5 (OSRAM
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ベンジャミン フライドマン，
アルドニア エル． バラシナス，
アンドレイ ブイ． ブロックヒン，
ヒラク エス． バス，
ロウレンス ジェイ． マートン，
ベノドハー ケイ． レディー，
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スリル バイオメディカル コーポレイション
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Publication of JP2005506354A publication Critical patent/JP2005506354A/ja
Publication of JP2005506354A5 publication Critical patent/JP2005506354A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/18—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
JP2003536196A 2001-10-16 2002-10-16 癌治療のためのオリゴアミン化合物およびその誘導体 Pending JP2005506354A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32998201P 2001-10-16 2001-10-16
PCT/US2002/032932 WO2003033455A1 (en) 2001-10-16 2002-10-16 Oligoamine compounds and derivatives thereof for cancer therapy

Publications (2)

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JP2005506354A true JP2005506354A (ja) 2005-03-03
JP2005506354A5 JP2005506354A5 (OSRAM) 2009-01-15

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JP2003536196A Pending JP2005506354A (ja) 2001-10-16 2002-10-16 癌治療のためのオリゴアミン化合物およびその誘導体

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US (3) US20030130356A1 (OSRAM)
EP (1) EP1436246A1 (OSRAM)
JP (1) JP2005506354A (OSRAM)
AU (2) AU2002340224B2 (OSRAM)
CA (1) CA2463771A1 (OSRAM)
IL (1) IL161428A0 (OSRAM)
WO (1) WO2003033455A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011503050A (ja) * 2007-11-08 2011-01-27 イッサム リサーチ ディべロップメント カンパニー オブ ザ ヘブライ ユニバーシティー オブ エルサレム，リミテッド スフィンゴリピドの新規合成アナログ

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WO2002038105A2 (en) 2000-11-08 2002-05-16 Slil Biomedical Corporation Novel polyamine analog-amino acid conjugates useful as anticancer agents
AU2002340224B2 (en) * 2001-10-16 2008-11-27 Progen Pharmaceuticals, Inc Oligoamine compounds and derivatives thereof for cancer therapy
WO2003050072A1 (en) 2001-12-07 2003-06-19 Slil Biomedical Corporation Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
WO2004002991A1 (en) * 2002-06-26 2004-01-08 Cellgate, Inc. Porphyrin-polyamine conjugates for cancer therapy
US7095075B2 (en) * 2003-07-01 2006-08-22 Micron Technology, Inc. Apparatus and method for split transistor memory having improved endurance
US7241654B2 (en) * 2003-12-17 2007-07-10 Micron Technology, Inc. Vertical NROM NAND flash memory array
US7075146B2 (en) * 2004-02-24 2006-07-11 Micron Technology, Inc. 4F2 EEPROM NROM memory arrays with vertical devices
MX2007004030A (es) * 2004-10-04 2008-01-14 Cellgate Inc Analogos de poliamina como agentes terapeuticos para enfermedades oculares.
WO2006086773A2 (en) * 2005-02-11 2006-08-17 Cellgate, Inc. Polyamine analogs as modulators of cell migration and cell motility
US20070232677A1 (en) * 2006-03-14 2007-10-04 Marton Laurence J Treatment and prevention of vascular hyperplasia using polyamine and polyamine analog compounds
FR2932088B1 (fr) * 2008-06-06 2013-04-05 Lvmh Rech Utilisation d'un extrait de lepechinia caulescens comme agent cosmetique, et composition cosmetique le contenant
CN113861268B (zh) 2014-05-21 2025-04-01 恩特拉达治疗学股份有限公司 细胞穿透肽及其制备和使用方法
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
EP3185880B1 (en) 2014-08-27 2020-02-12 Ohio State Innovation Foundation Improved peptidyl calcineurin inhibitors
US11339192B2 (en) 2017-10-04 2022-05-24 Ohio State Innovation Foundation Bicyclic peptidyl inhibitors
EP3746105A4 (en) 2018-01-29 2022-05-18 Ohio State Innovation Foundation CYCLIC PEPTIDYLIN HIBITORS OF THE CAL-PDZ-BINDING DOMAIN
WO2019148194A2 (en) 2018-01-29 2019-08-01 Ohio State Innovation Foundation Peptidyl inhibitors of calcineurin-nfat interaction
TW201945014A (zh) 2018-02-22 2019-12-01 美商安卓達治療股份有限公司 用於治療粒線體性神經胃腸腦病變之組合物及方法

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JP2011503050A (ja) * 2007-11-08 2011-01-27 イッサム リサーチ ディべロップメント カンパニー オブ ザ ヘブライ ユニバーシティー オブ エルサレム，リミテッド スフィンゴリピドの新規合成アナログ

Also Published As

Publication number Publication date
EP1436246A1 (en) 2004-07-14
US7491849B2 (en) 2009-02-17
WO2003033455A1 (en) 2003-04-24
US20030130356A1 (en) 2003-07-10
IL161428A0 (en) 2004-09-27
US20050080144A1 (en) 2005-04-14
AU2009200639A1 (en) 2009-03-12
US20090124832A1 (en) 2009-05-14
AU2002340224B2 (en) 2008-11-27
CA2463771A1 (en) 2003-04-24

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