JP2004538468A5 - - Google Patents
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- Publication number
- JP2004538468A5 JP2004538468A5 JP2003519572A JP2003519572A JP2004538468A5 JP 2004538468 A5 JP2004538468 A5 JP 2004538468A5 JP 2003519572 A JP2003519572 A JP 2003519572A JP 2003519572 A JP2003519572 A JP 2003519572A JP 2004538468 A5 JP2004538468 A5 JP 2004538468A5
- Authority
- JP
- Japan
- Prior art keywords
- hybrid
- group
- monolithic material
- surface modifier
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000463 material Substances 0.000 claims 75
- 239000003607 modifier Substances 0.000 claims 38
- 239000002245 particle Substances 0.000 claims 29
- 239000011148 porous material Substances 0.000 claims 16
- 239000000126 substance Substances 0.000 claims 14
- 125000005372 silanol group Chemical group 0.000 claims 13
- 238000004587 chromatography analysis Methods 0.000 claims 11
- 229920000642 polymer Polymers 0.000 claims 11
- 239000011248 coating agent Substances 0.000 claims 10
- 238000000576 coating method Methods 0.000 claims 10
- 125000000962 organic group Chemical group 0.000 claims 10
- 229910004298 SiO 2 Inorganic materials 0.000 claims 8
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 8
- 125000000217 alkyl group Chemical group 0.000 claims 8
- PYJJCSYBSYXGQQ-UHFFFAOYSA-N trichloro(octadecyl)silane Chemical compound CCCCCCCCCCCCCCCCCC[Si](Cl)(Cl)Cl PYJJCSYBSYXGQQ-UHFFFAOYSA-N 0.000 claims 8
- 125000003118 aryl group Chemical group 0.000 claims 6
- IJOOHPMOJXWVHK-UHFFFAOYSA-N chlorotrimethylsilane Chemical compound C[Si](C)(C)Cl IJOOHPMOJXWVHK-UHFFFAOYSA-N 0.000 claims 6
- 125000000524 functional group Chemical group 0.000 claims 6
- 239000000377 silicon dioxide Substances 0.000 claims 4
- RCHUVCPBWWSUMC-UHFFFAOYSA-N trichloro(octyl)silane Chemical group CCCCCCCC[Si](Cl)(Cl)Cl RCHUVCPBWWSUMC-UHFFFAOYSA-N 0.000 claims 4
- 230000004048 modification Effects 0.000 claims 3
- 238000012986 modification Methods 0.000 claims 3
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims 2
- 125000001931 aliphatic group Chemical group 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 125000004450 alkenylene group Chemical group 0.000 claims 2
- 125000002947 alkylene group Chemical group 0.000 claims 2
- 125000000304 alkynyl group Chemical group 0.000 claims 2
- 125000004419 alkynylene group Chemical group 0.000 claims 2
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims 2
- 238000005349 anion exchange Methods 0.000 claims 2
- 125000000732 arylene group Chemical group 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 2
- 238000005341 cation exchange Methods 0.000 claims 2
- 229910010293 ceramic material Inorganic materials 0.000 claims 2
- GZGREZWGCWVAEE-UHFFFAOYSA-N chloro-dimethyl-octadecylsilane Chemical compound CCCCCCCCCCCCCCCCCC[Si](C)(C)Cl GZGREZWGCWVAEE-UHFFFAOYSA-N 0.000 claims 2
- DBKNGKYVNBJWHL-UHFFFAOYSA-N chloro-dimethyl-octylsilane Chemical compound CCCCCCCC[Si](C)(C)Cl DBKNGKYVNBJWHL-UHFFFAOYSA-N 0.000 claims 2
- -1 cyano, amino Chemical group 0.000 claims 2
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 2
- 125000004663 dialkyl amino group Chemical group 0.000 claims 2
- 150000002009 diols Chemical class 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 2
- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 claims 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 claims 2
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 claims 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical group CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 2
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
- 125000005504 styryl group Chemical group 0.000 claims 2
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 2
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 claims 2
- ITMCEJHCFYSIIV-UHFFFAOYSA-M triflate Chemical compound [O-]S(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-M 0.000 claims 2
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 2
- 229920002554 vinyl polymer Chemical group 0.000 claims 2
- 229910001928 zirconium oxide Inorganic materials 0.000 claims 2
- 125000003837 (C1-C20) alkyl group Chemical group 0.000 claims 1
- 125000000923 (C1-C30) alkyl group Chemical group 0.000 claims 1
- 239000010419 fine particle Substances 0.000 claims 1
- SLYCYWCVSGPDFR-UHFFFAOYSA-N octadecyltrimethoxysilane Chemical compound CCCCCCCCCCCCCCCCCC[Si](OC)(OC)OC SLYCYWCVSGPDFR-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31144501P | 2001-08-09 | 2001-08-09 | |
| PCT/US2002/025193 WO2003014450A1 (en) | 2001-08-09 | 2002-08-08 | Porous inorganic/organic hybrid monolith materials for chromatographic separations and process for their preparation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008236842A Division JP5089543B2 (ja) | 2001-08-09 | 2008-09-16 | クロマトグラフィー分離用多孔質有機・無機ハイブリッドモノリス状物質、およびその製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004538468A JP2004538468A (ja) | 2004-12-24 |
| JP2004538468A5 true JP2004538468A5 (cg-RX-API-DMAC7.html) | 2006-01-05 |
| JP4216716B2 JP4216716B2 (ja) | 2009-01-28 |
Family
ID=23206890
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003519572A Expired - Fee Related JP4216716B2 (ja) | 2001-08-09 | 2002-08-08 | クロマトグラフィー分離用多孔質有機・無機ハイブリッドモノリス状物質、およびその製造方法 |
| JP2008236842A Expired - Lifetime JP5089543B2 (ja) | 2001-08-09 | 2008-09-16 | クロマトグラフィー分離用多孔質有機・無機ハイブリッドモノリス状物質、およびその製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008236842A Expired - Lifetime JP5089543B2 (ja) | 2001-08-09 | 2008-09-16 | クロマトグラフィー分離用多孔質有機・無機ハイブリッドモノリス状物質、およびその製造方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US7250214B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1417366A4 (cg-RX-API-DMAC7.html) |
| JP (2) | JP4216716B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003014450A1 (cg-RX-API-DMAC7.html) |
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-
2002
- 2002-08-08 JP JP2003519572A patent/JP4216716B2/ja not_active Expired - Fee Related
- 2002-08-08 US US10/216,674 patent/US7250214B2/en not_active Expired - Lifetime
- 2002-08-08 EP EP02759304A patent/EP1417366A4/en not_active Withdrawn
- 2002-08-08 WO PCT/US2002/025193 patent/WO2003014450A1/en not_active Ceased
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2006
- 2006-12-21 US US11/644,279 patent/US8404346B2/en not_active Expired - Fee Related
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2008
- 2008-09-16 JP JP2008236842A patent/JP5089543B2/ja not_active Expired - Lifetime
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2013
- 2013-03-25 US US13/850,212 patent/US9089836B2/en not_active Expired - Fee Related
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