JP2004537554A5 - - Google Patents

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Publication number
JP2004537554A5
JP2004537554A5 JP2003513970A JP2003513970A JP2004537554A5 JP 2004537554 A5 JP2004537554 A5 JP 2004537554A5 JP 2003513970 A JP2003513970 A JP 2003513970A JP 2003513970 A JP2003513970 A JP 2003513970A JP 2004537554 A5 JP2004537554 A5 JP 2004537554A5
Authority
JP
Japan
Prior art keywords
compound
optionally substituted
phenyl
pharmaceutical composition
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2003513970A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004537554A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/022897 external-priority patent/WO2003008411A1/en
Publication of JP2004537554A publication Critical patent/JP2004537554A/ja
Publication of JP2004537554A5 publication Critical patent/JP2004537554A5/ja
Ceased legal-status Critical Current

Links

JP2003513970A 2001-07-19 2002-07-18 置換されたピペラジン化合物および脂肪酸酸化インヒビターとしてのその使用 Ceased JP2004537554A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30662101P 2001-07-19 2001-07-19
PCT/US2002/022897 WO2003008411A1 (en) 2001-07-19 2002-07-18 Substituted piperazine compounds and their use as fatty acid oxidation inhibitors

Publications (2)

Publication Number Publication Date
JP2004537554A JP2004537554A (ja) 2004-12-16
JP2004537554A5 true JP2004537554A5 (enExample) 2006-01-05

Family

ID=23186103

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003513970A Ceased JP2004537554A (ja) 2001-07-19 2002-07-18 置換されたピペラジン化合物および脂肪酸酸化インヒビターとしてのその使用

Country Status (21)

Country Link
US (1) US6930111B2 (enExample)
EP (1) EP1406898B1 (enExample)
JP (1) JP2004537554A (enExample)
KR (1) KR100919141B1 (enExample)
CN (1) CN1533388A (enExample)
AT (1) ATE292633T1 (enExample)
AU (1) AU2008202958A1 (enExample)
CA (1) CA2454059A1 (enExample)
DE (1) DE60203623T2 (enExample)
DK (1) DK1406898T3 (enExample)
ES (1) ES2236557T3 (enExample)
HU (1) HUP0402088A3 (enExample)
IL (1) IL159897A0 (enExample)
MX (1) MXPA04000565A (enExample)
NO (1) NO327635B1 (enExample)
NZ (1) NZ530705A (enExample)
PL (1) PL368529A1 (enExample)
PT (1) PT1406898E (enExample)
RU (1) RU2300533C2 (enExample)
WO (1) WO2003008411A1 (enExample)
ZA (1) ZA200400404B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7001909B2 (en) * 2001-07-19 2006-02-21 Cv Therapeutics, Inc. Substituted heterocyclic compounds
IL165304A0 (en) 2002-05-21 2006-01-15 Cv Therapeutics Inc Method of treating diabetes
US8822473B2 (en) * 2002-05-21 2014-09-02 Gilead Sciences, Inc. Method of treating diabetes
AU2003268064A1 (en) * 2002-08-09 2004-02-25 Astrazeneca Ab Oxadiazoles as modulators of metabotropic glutamate receptor-5
CN1894241A (zh) 2002-08-09 2007-01-10 阿斯利康(瑞典)有限公司 作为代谢型谷氨酸受体-5调节剂的“1,2,4” 噁二唑
AU2003264018A1 (en) * 2002-08-09 2004-02-25 Astrazeneca Ab Compounds having an activity at metabotropic glutamate receptors
EP1567525B1 (en) * 2002-12-05 2007-06-27 Cv Therapeutics, Inc. Substituted piperazine compounds and their use as fatty acid oxidation inhibitors
EP1806346B1 (en) * 2002-12-05 2009-07-22 Cv Therapeutics, Inc. Substituted piperazine compounds and their use as fatty acid oxidation inhibitors
ATE443058T1 (de) 2003-01-03 2009-10-15 Cv Therapeutics Inc Substituierte heterozyklische verbindungen
JP2006515891A (ja) * 2003-01-17 2006-06-08 シーブイ・セラピューティクス・インコーポレイテッド 循環器疾患の処置に有効な置換ヘテロ環化合物
JP2007518677A (ja) * 2003-06-23 2007-07-12 シーブイ・セラピューティクス・インコーポレイテッド 脂肪酸酸化インヒビターとしてのピペラジンおよびピペリジンのウレア誘導体
KR20060124646A (ko) 2003-12-18 2006-12-05 씨브이 쎄러퓨틱스, 인코포레이티드 1-아칸-2-올 치환된 피페라진 및 피페리딘 화합물
EP1699527A1 (en) 2004-01-02 2006-09-13 Advanced Cardiovascular Systems, Inc. High-density lipoprotein coated medical devices
KR20070051305A (ko) * 2004-09-08 2007-05-17 씨브이 쎄러퓨틱스, 인코포레이티드 치환된 피페라진 화합물 및 지방산 산화 저해제로서의 이의용도
CN101541331A (zh) 2006-08-24 2009-09-23 沃克哈特研究中心 具有抗微生物活性的新颖大环内酯和酮内酯
US8088920B2 (en) * 2008-03-31 2012-01-03 Hoffmann-La Roche Inc. 3-trifluoromethyl-pyrazine-2-carboxylic acid amide derivatives as HDL-cholesterol raising agents
SMT201700147T1 (it) * 2008-10-10 2017-05-08 Vm Discovery Inc Composizioni e metodi per il trattamento dei disturbi da uso di alcol, dolore e altre malattie
MX2011012140A (es) * 2009-05-14 2012-02-28 Gilead Sciences Inc Ranolazina para el tratamiento de problemas del snc.
JPWO2011115150A1 (ja) * 2010-03-18 2013-07-04 興和株式会社 ベンゾチアジン化合物の製造方法
CN111285819A (zh) * 2018-12-07 2020-06-16 江苏恩华药业股份有限公司 一种苯并噁唑类化合物及其应用
WO2023023995A1 (zh) * 2021-08-25 2023-03-02 苏州大学 一种防治心肌缺血后心功能衰竭的药物及其应用

Family Cites Families (19)

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Publication number Priority date Publication date Assignee Title
GB1133989A (en) 1964-12-08 1968-11-20 Chugai Pharmaceutical Co Ltd Theophylline derivatives, their salts and process for preparing the same
DE2834114A1 (de) * 1978-08-01 1980-02-14 Schering Ag Polyalkoxyphenylpyrrolidone iii, verfahren zu ihrer herstellung und ihre verwendung
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
JPS6137765A (ja) * 1984-07-19 1986-02-22 サンド・アクチエンゲゼルシヤフト 3‐アミノプロポキシアリール誘導体
US4723014A (en) * 1986-11-19 1988-02-02 Warner-Lambert Company Process for the preparation of 2-substituted-1,4-dihydropyridines
DE3723648A1 (de) * 1987-07-17 1989-01-26 Sandoz Ag Indol-derivate, ihre herstellung und sie enthaltende arzneimittel
JPH0699399B2 (ja) * 1988-10-06 1994-12-07 三井東圧化学株式会社 新規複素環化合物およびそれを有効成分として含有する製癌剤効果増強剤
JPH02268162A (ja) * 1989-04-10 1990-11-01 Fujisawa Pharmaceut Co Ltd ジフェニルピリジン誘導体
MX9308025A (es) * 1992-12-22 1994-08-31 Lilly Co Eli Compuestos inhibidores de la proteasa del virus dela inmunodeficiencia humana, procedimiento para supreparacion y formulacion farmaceutica que los contiene.
AU5170698A (en) * 1996-11-14 1998-06-03 American Home Products Corporation Substituted tetrahydro-1,3,5-triazin-2{1h}-thiones as anti-atherosclerotic agents
HUP0202679A3 (en) * 1999-09-13 2003-04-28 Wyeth Corp Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1h-indol-5-ols, process for their preparation and pharmaceutical compositions containing them
SE9904765D0 (sv) 1999-12-23 1999-12-23 Astra Ab Pharmaceutically-useful compounds
US6677343B2 (en) 2000-02-22 2004-01-13 Cv Therapeutics, Inc. Substituted piperazine compounds
US6552023B2 (en) 2000-02-22 2003-04-22 Cv Therapeutics, Inc. Aralkyl substituted piperazine compounds
WO2001062711A2 (en) * 2000-02-22 2001-08-30 Cv Therapeutics, Inc. Substituted alkylene diamine compounds
EP1259493A2 (en) * 2000-02-22 2002-11-27 Cv Therapeutics, Inc. Substituted piperazine compounds
US6451798B2 (en) 2000-02-22 2002-09-17 Cv Therapeutics, Inc. Substituted alkyl piperazine derivatives
SE0003795D0 (sv) * 2000-10-20 2000-10-20 Astrazeneca Ab Pharmaceutically useful compounds
US6573264B1 (en) 2000-10-23 2003-06-03 Cv Therapeutics, Inc. Heteroaryl alkyl piperazine derivatives

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