JP2004525957A5 - - Google Patents
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- Publication number
- JP2004525957A5 JP2004525957A5 JP2002580924A JP2002580924A JP2004525957A5 JP 2004525957 A5 JP2004525957 A5 JP 2004525957A5 JP 2002580924 A JP2002580924 A JP 2002580924A JP 2002580924 A JP2002580924 A JP 2002580924A JP 2004525957 A5 JP2004525957 A5 JP 2004525957A5
- Authority
- JP
- Japan
- Prior art keywords
- sodium
- product
- pharmaceutical composition
- sodium caprate
- csf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FIWQZURFGYXCEO-UHFFFAOYSA-M sodium;decanoate Chemical compound [Na+].CCCCCCCCCC([O-])=O FIWQZURFGYXCEO-UHFFFAOYSA-M 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 229960005480 sodium caprylate Drugs 0.000 claims 3
- BYKRNSHANADUFY-UHFFFAOYSA-M sodium octanoate Chemical compound [Na+].CCCCCCCC([O-])=O BYKRNSHANADUFY-UHFFFAOYSA-M 0.000 claims 3
- 102000004127 Cytokines Human genes 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 2
- 208000004235 neutropenia Diseases 0.000 claims 2
- 208000019838 Blood disease Diseases 0.000 claims 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 claims 1
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 claims 1
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 1
- 102000003812 Interleukin-15 Human genes 0.000 claims 1
- 108090000172 Interleukin-15 Proteins 0.000 claims 1
- 102000000588 Interleukin-2 Human genes 0.000 claims 1
- 108010002350 Interleukin-2 Proteins 0.000 claims 1
- 208000002720 Malnutrition Diseases 0.000 claims 1
- 239000012190 activator Substances 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 238000010322 bone marrow transplantation Methods 0.000 claims 1
- 230000001332 colony forming effect Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 208000014951 hematologic disease Diseases 0.000 claims 1
- 208000018706 hematopoietic system disease Diseases 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 235000018343 nutrient deficiency Nutrition 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 230000001629 suppression Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28445801P | 2001-04-18 | 2001-04-18 | |
| US60/284,458 | 2001-04-18 | ||
| PCT/CA2002/000535 WO2002083120A2 (en) | 2001-04-18 | 2002-04-18 | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009272679A Division JP5657879B2 (ja) | 2001-04-18 | 2009-11-30 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004525957A JP2004525957A (ja) | 2004-08-26 |
| JP2004525957A5 true JP2004525957A5 (https=) | 2009-08-20 |
| JP5026655B2 JP5026655B2 (ja) | 2012-09-12 |
Family
ID=23090294
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002580924A Expired - Lifetime JP5026655B2 (ja) | 2001-04-18 | 2002-04-18 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
| JP2009272679A Expired - Lifetime JP5657879B2 (ja) | 2001-04-18 | 2009-11-30 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
| JP2014165557A Expired - Lifetime JP6420089B2 (ja) | 2001-04-18 | 2014-08-15 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009272679A Expired - Lifetime JP5657879B2 (ja) | 2001-04-18 | 2009-11-30 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
| JP2014165557A Expired - Lifetime JP6420089B2 (ja) | 2001-04-18 | 2014-08-15 | 好中球の生存及び活性化因子としての中鎖脂肪酸、グリセリド及び類似体 |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US7745488B2 (https=) |
| EP (2) | EP1385498B1 (https=) |
| JP (3) | JP5026655B2 (https=) |
| KR (1) | KR20030096323A (https=) |
| CN (1) | CN1633286A (https=) |
| AP (1) | AP1740A (https=) |
| AU (2) | AU2002308456B2 (https=) |
| BG (1) | BG66418B1 (https=) |
| BR (1) | BR0208984A (https=) |
| CA (2) | CA2763637C (https=) |
| CY (1) | CY1107081T1 (https=) |
| CZ (1) | CZ305273B6 (https=) |
| DE (1) | DE60223670T2 (https=) |
| DK (2) | DK1900364T3 (https=) |
| EA (1) | EA007322B1 (https=) |
| EE (1) | EE200300510A (https=) |
| ES (2) | ES2439738T3 (https=) |
| HU (1) | HUP0303817A3 (https=) |
| IL (3) | IL158322A0 (https=) |
| MX (1) | MXPA03009436A (https=) |
| NO (1) | NO335105B1 (https=) |
| NZ (2) | NZ541140A (https=) |
| OA (1) | OA12506A (https=) |
| PL (2) | PL223348B1 (https=) |
| PT (2) | PT1385498E (https=) |
| SI (1) | SI1385498T1 (https=) |
| SK (1) | SK12772003A3 (https=) |
| TN (1) | TNSN03089A1 (https=) |
| WO (1) | WO2002083120A2 (https=) |
| ZA (1) | ZA200307778B (https=) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL158322A0 (en) | 2001-04-18 | 2004-05-12 | Prometic Biosciences Inc | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
| DK1592416T3 (da) * | 2003-02-07 | 2009-04-20 | Prometic Biosciences Inc | Fedtsyrer med middel kædelængde, glycerider og analoger som stimulatorer af erythropoiesis |
| JP5214880B2 (ja) | 2003-07-25 | 2013-06-19 | プロメティック、バイオサイエンシーズ、インコーポレーテッド | 中鎖脂肪酸の金属塩の製造 |
| US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
| US8241670B2 (en) * | 2004-04-15 | 2012-08-14 | Chiasma Inc. | Compositions capable of facilitating penetration across a biological barrier |
| KR20070063507A (ko) * | 2004-09-03 | 2007-06-19 | 프로메틱 바이오사이언시즈 인코포레이티드 | 면역조절작용과 화학방어활성을 가진 치환된 퓨리닐 유도체및 단독 또는 중쇄 길이 지방산이나 글리세리드와의 혼합사용 |
| US8071580B2 (en) | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
| MX2007003967A (es) * | 2004-10-01 | 2008-03-04 | Prometic Biosciences Inc | Alcoholes grasos con longitud de cadena media como estimuladores de hematopoyesis. |
| AU2006217544B8 (en) * | 2005-02-28 | 2012-04-05 | Alphabeta Ab | Compounds for reducing aggregation of amyloid beta-peptide |
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| EP2679224A1 (en) | 2007-08-01 | 2014-01-01 | University of Pittsburgh of the Commonwealth System of Higher Education | Nitro oleic acid modulation of type II diabetes |
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| EP2394636B1 (en) * | 2010-05-28 | 2014-03-19 | Novagali Pharma S.A. | Method for treating retinal conditions using an intraocular tamponade |
| EP2744491B1 (en) | 2011-08-19 | 2020-07-29 | The University of Utah Research Foundation | Combination therapy with nitrated lipids and inhibitors of the renin-angiotensin-aldosterone system |
| TWI572352B (zh) * | 2012-03-01 | 2017-03-01 | 波麥堤克藥學Smt有限公司 | 用於製備具中鏈長度之脂肪酸的三酸甘油酯之方法 |
| CN108498532B (zh) | 2012-05-09 | 2021-07-23 | 坎泰克斯制药股份有限公司 | 骨髓抑制的治疗 |
| KR101621856B1 (ko) | 2013-08-19 | 2016-05-17 | 한국생명공학연구원 | 모노아세틸디아실글리세롤 화합물을 유효성분으로 함유하는 류마티스 관절염의 예방 또는 치료용 조성물 |
| CA3037762C (en) | 2014-05-15 | 2022-03-22 | Enzychem Lifesciences Corporation | Methods for treating leukopenia and thrombocytopenia |
| HUE071943T2 (hu) | 2015-02-03 | 2025-10-28 | Amryt Endo Inc | Akromegália kezelése oktreotid orális alkalmazásával |
| US10052346B2 (en) | 2015-02-17 | 2018-08-21 | Cantex Pharmaceuticals, Inc. | Treatment of myelodysplastic syndromes with 2-O and,or 3-O desulfated heparinoids |
| HRP20240082T1 (hr) | 2015-07-07 | 2024-03-29 | H. Lundbeck A/S | Inhibitor pde9 s okosnicom imidazopirazinona za liječenje perifernih bolesti |
| IL258476B2 (en) | 2015-10-02 | 2023-04-01 | Complexa Inc | Prevention, treatment and reversal of disease using therapeutically effective amounts of activated fatty acids |
| US9808438B2 (en) * | 2015-11-09 | 2017-11-07 | Enzychem Lifesciences Corporation | Method for treating mucositis |
| EP3928776B1 (en) | 2016-04-22 | 2025-11-12 | Spoke Sciences, Inc. | Fast-acting plant-based medicinal compounds and nutritional supplements |
| US11406616B2 (en) | 2016-06-08 | 2022-08-09 | Sunregen Healthcare Ag | Lipids with odd number of carbon atoms and their use as pharmaceutical composition or nutritional supplement |
| EA201892396A1 (ru) | 2016-12-02 | 2019-04-30 | Ресептор Лайф Сайенсиз, Инк. | Быстродействующие растительные лекарственные соединения и биологически активные добавки |
| CN107382710B (zh) * | 2017-08-19 | 2020-11-06 | 中国铁道科学研究院集团有限公司铁道建筑研究所 | 一种接枝抗氧剂分子的多元醇 |
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| CA3078549A1 (en) * | 2017-10-05 | 2019-04-11 | Receptor Holdings, Inc. | Rapid onset and extended action plant-based and synthetic cannabinoid formulations |
| KR102054401B1 (ko) * | 2018-03-26 | 2019-12-10 | 주식회사 엔지켐생명과학 | 1,2-디아실글리세롤 화합물, 그 제조방법 및 이를 유효성분으로 함유하는 면역조절제 |
| FI3801526T3 (fi) | 2018-05-25 | 2024-03-20 | Cardurion Pharmaceuticals Inc | 6-[(3s,4s)-4-metyyli-1-(pyrimidin-2-yylimetyyli)pyrrolidin-3-yyli]-3-tetrahydropyran-4-yyli-7h-imidatso[1,5-a]pyratsin-8-onin monohydraattimuotoja ja kiteisiä muotoja |
| EP3843737A4 (en) | 2018-08-31 | 2022-06-01 | Imara Inc. | PDE9 INHIBITORS FOR THE TREATMENT OF SICKLE CELL DISEASE |
| MA53188A1 (fr) | 2018-10-11 | 2021-12-31 | Basf As | Composés aromatiques et leurs utilisations pharmaceutiques |
| AU2019385420A1 (en) | 2018-11-19 | 2021-07-08 | Spoke Sciences, Inc. | N-acylated fatty amino acids to reduce absorption variability in cannabinoid based compositions |
| JP7735864B2 (ja) * | 2019-10-31 | 2025-09-09 | 日本ゼオン株式会社 | 電気化学素子用機能層およびその製造方法、電気化学素子用機能層付きセパレータおよびその製造方法、並びに電気化学素子およびその製造方法 |
| US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
| US20240415798A1 (en) * | 2021-10-18 | 2024-12-19 | Enzychem Lifesciences Corporation | Compositions and methods for treating mucositis |
| CN119421865A (zh) * | 2022-04-21 | 2025-02-11 | 默沙东有限责任公司 | 制备附聚的结晶中链脂肪酸钠盐的方法 |
| WO2026013252A1 (en) * | 2024-07-12 | 2026-01-15 | Paoli Alessio | A mixture of mono-, di- and triglycerides of nonanoic acid for use in the treatment of muscle atrophy, sarcopenia and muscle-injury |
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| JP5214880B2 (ja) | 2003-07-25 | 2013-06-19 | プロメティック、バイオサイエンシーズ、インコーポレーテッド | 中鎖脂肪酸の金属塩の製造 |
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-
2002
- 2002-04-18 IL IL15832202A patent/IL158322A0/xx active IP Right Grant
- 2002-04-18 DK DK07116425.5T patent/DK1900364T3/da active
- 2002-04-18 BR BR0208984-0A patent/BR0208984A/pt not_active Application Discontinuation
- 2002-04-18 EP EP02761857A patent/EP1385498B1/en not_active Expired - Lifetime
- 2002-04-18 CA CA2763637A patent/CA2763637C/en not_active Expired - Lifetime
- 2002-04-18 CA CA2444463A patent/CA2444463C/en not_active Expired - Lifetime
- 2002-04-18 PT PT02761857T patent/PT1385498E/pt unknown
- 2002-04-18 EE EEP200300510A patent/EE200300510A/xx unknown
- 2002-04-18 EP EP07116425.5A patent/EP1900364B1/en not_active Expired - Lifetime
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