JP2021512164A5 - - Google Patents

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Publication number
JP2021512164A5
JP2021512164A5 JP2020562093A JP2020562093A JP2021512164A5 JP 2021512164 A5 JP2021512164 A5 JP 2021512164A5 JP 2020562093 A JP2020562093 A JP 2020562093A JP 2020562093 A JP2020562093 A JP 2020562093A JP 2021512164 A5 JP2021512164 A5 JP 2021512164A5
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JP
Japan
Prior art keywords
cells
cell line
tgf
pharmaceutical composition
tgfβi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020562093A
Other languages
English (en)
Japanese (ja)
Other versions
JP7591406B2 (ja
JP2021512164A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/015617 external-priority patent/WO2019152387A1/en
Publication of JP2021512164A publication Critical patent/JP2021512164A/ja
Publication of JP2021512164A5 publication Critical patent/JP2021512164A5/ja
Priority to JP2024200825A priority Critical patent/JP2025026937A/ja
Application granted granted Critical
Publication of JP7591406B2 publication Critical patent/JP7591406B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020562093A 2018-01-30 2019-01-29 トランスフォーミング増殖因子ベータ抵抗性ナチュラルキラー細胞 Active JP7591406B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024200825A JP2025026937A (ja) 2018-01-30 2024-11-18 トランスフォーミング増殖因子ベータ抵抗性ナチュラルキラー細胞

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862623682P 2018-01-30 2018-01-30
US62/623,682 2018-01-30
PCT/US2019/015617 WO2019152387A1 (en) 2018-01-30 2019-01-29 Transforming growth factor beta-resistant natural killer cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024200825A Division JP2025026937A (ja) 2018-01-30 2024-11-18 トランスフォーミング増殖因子ベータ抵抗性ナチュラルキラー細胞

Publications (3)

Publication Number Publication Date
JP2021512164A JP2021512164A (ja) 2021-05-13
JP2021512164A5 true JP2021512164A5 (https=) 2022-01-27
JP7591406B2 JP7591406B2 (ja) 2024-11-28

Family

ID=67478491

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020562093A Active JP7591406B2 (ja) 2018-01-30 2019-01-29 トランスフォーミング増殖因子ベータ抵抗性ナチュラルキラー細胞
JP2024200825A Pending JP2025026937A (ja) 2018-01-30 2024-11-18 トランスフォーミング増殖因子ベータ抵抗性ナチュラルキラー細胞

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024200825A Pending JP2025026937A (ja) 2018-01-30 2024-11-18 トランスフォーミング増殖因子ベータ抵抗性ナチュラルキラー細胞

Country Status (12)

Country Link
US (1) US20200368281A1 (https=)
EP (1) EP3746118A4 (https=)
JP (2) JP7591406B2 (https=)
KR (2) KR20250093419A (https=)
CN (1) CN111818941A (https=)
AU (1) AU2019213678B2 (https=)
BR (1) BR112020015490A2 (https=)
CA (1) CA3090096A1 (https=)
IL (2) IL309656A (https=)
MX (1) MX2020008044A (https=)
SG (1) SG11202007288VA (https=)
WO (1) WO2019152387A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021183776A1 (en) * 2020-03-11 2021-09-16 Research Institute At Nationwide Children's Hospital Nk cells and uses thereof for treatment of microbial infections
MX2022012792A (es) * 2020-04-30 2023-02-14 Res Institute At Nationwide Children´S Hospital Superar la inmunosupresion con celulas nk resistentes a tgf-\03b2.
CN120882419A (zh) * 2023-03-02 2025-10-31 全国儿童医院研究所 用于癌症免疫疗法的转化生长因子-β超家族印记的自然杀伤细胞

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2058388A1 (en) * 2007-10-05 2009-05-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Non-conventional NKT cells for use in cancer therapy
CN105143441B (zh) * 2014-01-13 2019-11-08 张明杰 用带有活性因子的细胞空壳作为淋巴细胞体外培养增效剂的制备及其应用方法
HK1245080A1 (zh) * 2014-10-27 2018-08-24 University Of Central Florida Research Foundation, Inc. 自然杀伤细胞的方法和组合物
KR20180040706A (ko) * 2015-09-01 2018-04-20 인네이트 튜머 이뮤니티, 인코포레이티드 면역억제 시토카인에 대해 증가된 면역 또는 저항성을 갖는 면역 세포 및 그의 용도
CN116376825A (zh) * 2015-09-14 2023-07-04 明尼苏达大学董事会 表现出适应性表型的nk细胞以及制备和使用方法

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