JP2004525898A - 両性リポソーム及びその使用 - Google Patents
両性リポソーム及びその使用 Download PDFInfo
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- JP2004525898A JP2004525898A JP2002565572A JP2002565572A JP2004525898A JP 2004525898 A JP2004525898 A JP 2004525898A JP 2002565572 A JP2002565572 A JP 2002565572A JP 2002565572 A JP2002565572 A JP 2002565572A JP 2004525898 A JP2004525898 A JP 2004525898A
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- Prior art keywords
- liposomes
- liposome
- amphoteric
- charge carrier
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000004480 active ingredient Substances 0.000 claims description 27
- 239000000126 substance Substances 0.000 claims description 17
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- 238000000034 method Methods 0.000 claims description 11
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10109897A DE10109897A1 (de) | 2001-02-21 | 2001-02-21 | Fakultativ kationische Liposomen und Verwendung dieser |
| PCT/EP2002/001880 WO2002066012A2 (de) | 2001-02-21 | 2002-02-21 | Amphotere liposomen und verwendung dieser |
Related Child Applications (1)
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| WO1999006026A1 (en) * | 1997-07-30 | 1999-02-11 | Biovector Therapeutics (S.A.) | Stable particulate complexes with neutral or negative global charge of lamellar structure |
| WO1999012523A1 (en) * | 1997-09-08 | 1999-03-18 | Skyepharma Inc. | Modulation of drug loading in multivesicular liposomes |
| JPH11302199A (ja) * | 1998-04-16 | 1999-11-02 | Sankyo Co Ltd | 薬物運搬体を構成するグラフト共重合体 |
| JP2000198731A (ja) * | 1998-10-29 | 2000-07-18 | Sankyo Co Ltd | 毒性の低減されたリポソ―ム |
| WO2000059474A1 (en) * | 1999-04-06 | 2000-10-12 | Isis Pharmaceuticals, Inc. | Fusogenic lipids and vesicles |
| JP2001502299A (ja) * | 1996-09-13 | 2001-02-20 | リポゼン リミテッド | リポソーム |
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- 2002-02-21 AU AU2002234643A patent/AU2002234643B2/en not_active Ceased
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011021026A (ja) * | 2001-02-21 | 2011-02-03 | Novosom Ag | 両性リポソーム及びその使用 |
| JP2016104786A (ja) * | 2001-02-21 | 2016-06-09 | マリナ バイオテック インコーポレイテッド | 両性リポソーム及びその使用 |
| JP2009507876A (ja) * | 2005-09-15 | 2009-02-26 | ノヴォソム アクチェンゲゼルシャフト | 両性リポソームにおけるまたはそれに関する改善 |
| JP2009518297A (ja) * | 2005-12-01 | 2009-05-07 | プロネイ・セラピューティクス・インコーポレイテッド | 両性リポソーム製剤 |
| JP2010505899A (ja) * | 2006-10-13 | 2010-02-25 | ノヴォソム アクチェンゲゼルシャフト | 両性リポソームにおけるまたは両性リポソームに関する改善、両性リポソームを処方する方法および両性リポソームに充填する方法 |
| JP2010513354A (ja) * | 2006-12-19 | 2010-04-30 | ノヴォソム アクチェンゲゼルシャフト | トランスフェクションエンハンサー要素を含む脂質および脂質集合体 |
| JP2011500520A (ja) * | 2007-10-12 | 2011-01-06 | ノヴォソム アクチェンゲゼルシャフト | 中性脂質を含有する両性リポソームの改良または該両性リポソームに関連する改良 |
| JP2015110625A (ja) * | 2007-10-12 | 2015-06-18 | マリーナ バイオテック，インコーポレイテッド | 中性脂質を含む両性リポソーム |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002234643B2 (en) | 2007-06-21 |
| DE10109897A1 (de) | 2002-11-07 |
| EP1363601B1 (de) | 2007-06-06 |
| EP1363601A2 (de) | 2003-11-26 |
| CN1241549C (zh) | 2006-02-15 |
| CA2438116C (en) | 2011-10-11 |
| US20070252295A1 (en) | 2007-11-01 |
| JP2016104786A (ja) | 2016-06-09 |
| JP5480764B2 (ja) | 2014-04-23 |
| BR0207775A (pt) | 2004-03-30 |
| US20030099697A1 (en) | 2003-05-29 |
| US20110293695A1 (en) | 2011-12-01 |
| BRPI0207775B1 (pt) | 2015-10-20 |
| WO2002066012A3 (de) | 2002-12-19 |
| CA2438116A1 (en) | 2002-08-29 |
| US20070269504A1 (en) | 2007-11-22 |
| JP2011021026A (ja) | 2011-02-03 |
| JP2014031383A (ja) | 2014-02-20 |
| US7371404B2 (en) | 2008-05-13 |
| JP2014218520A (ja) | 2014-11-20 |
| WO2002066012A2 (de) | 2002-08-29 |
| US7780983B2 (en) | 2010-08-24 |
| CN1492756A (zh) | 2004-04-28 |
| ATE363893T1 (de) | 2007-06-15 |
| ES2289079T3 (es) | 2008-02-01 |
| DE50210271D1 (de) | 2007-07-19 |
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