JP2004522774A5 - - Google Patents

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Publication number
JP2004522774A5
JP2004522774A5 JP2002565596A JP2002565596A JP2004522774A5 JP 2004522774 A5 JP2004522774 A5 JP 2004522774A5 JP 2002565596 A JP2002565596 A JP 2002565596A JP 2002565596 A JP2002565596 A JP 2002565596A JP 2004522774 A5 JP2004522774 A5 JP 2004522774A5
Authority
JP
Japan
Prior art keywords
methyl
dihydroxy
thiazolyl
ethenyl
dione
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002565596A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004522774A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/004255 external-priority patent/WO2002066038A1/en
Publication of JP2004522774A publication Critical patent/JP2004522774A/ja
Publication of JP2004522774A5 publication Critical patent/JP2004522774A5/ja
Pending legal-status Critical Current

Links

JP2002565596A 2001-02-20 2002-02-06 エポチロン誘導体を用いる耐性腫瘍の治療 Pending JP2004522774A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26983601P 2001-02-20 2001-02-20
PCT/US2002/004255 WO2002066038A1 (en) 2001-02-20 2002-02-06 Treatment of refractory tumors using epothilone derivatives

Publications (2)

Publication Number Publication Date
JP2004522774A JP2004522774A (ja) 2004-07-29
JP2004522774A5 true JP2004522774A5 (enExample) 2005-12-22

Family

ID=23028846

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002565596A Pending JP2004522774A (ja) 2001-02-20 2002-02-06 エポチロン誘導体を用いる耐性腫瘍の治療

Country Status (18)

Country Link
US (2) US6686380B2 (enExample)
EP (1) EP1385529A4 (enExample)
JP (1) JP2004522774A (enExample)
KR (1) KR20040025895A (enExample)
CN (1) CN1774253A (enExample)
BG (1) BG108075A (enExample)
BR (1) BR0207487A (enExample)
CA (1) CA2438610A1 (enExample)
EE (1) EE200300396A (enExample)
HU (1) HUP0303175A2 (enExample)
IL (1) IL156988A0 (enExample)
IS (1) IS6918A (enExample)
MX (1) MXPA03007394A (enExample)
NO (1) NO20033684L (enExample)
PL (1) PL363362A1 (enExample)
RU (1) RU2003128311A (enExample)
WO (1) WO2002066038A1 (enExample)
ZA (1) ZA200306173B (enExample)

Families Citing this family (26)

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US6204388B1 (en) * 1996-12-03 2001-03-20 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
EP0977563B1 (en) 1996-12-03 2005-10-12 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US20050043376A1 (en) * 1996-12-03 2005-02-24 Danishefsky Samuel J. Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US6605599B1 (en) 1997-07-08 2003-08-12 Bristol-Myers Squibb Company Epothilone derivatives
US6780620B1 (en) * 1998-12-23 2004-08-24 Bristol-Myers Squibb Company Microbial transformation method for the preparation of an epothilone
US20020058286A1 (en) * 1999-02-24 2002-05-16 Danishefsky Samuel J. Synthesis of epothilones, intermediates thereto and analogues thereof
RU2003126171A (ru) * 2001-01-25 2005-02-27 Бристол-Маерс Сквибб Компани (Us) Парентеральный состав, содержащий аналоги эпотилона
WO2002072085A1 (en) * 2001-03-14 2002-09-19 Bristol-Myers Squibb Company Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases
TW200403994A (en) * 2002-04-04 2004-03-16 Bristol Myers Squibb Co Oral administration of EPOTHILONES
TW200400191A (en) * 2002-05-15 2004-01-01 Bristol Myers Squibb Co Pharmaceutical compositions and methods of using C-21 modified epothilone derivatives
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
US6921769B2 (en) 2002-08-23 2005-07-26 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
WO2004018478A2 (en) * 2002-08-23 2004-03-04 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
JP2006504743A (ja) 2002-10-09 2006-02-09 コーザン バイオサイエンシス インコーポレイテッド 治療製剤
TW200503738A (en) * 2003-07-16 2005-02-01 Tzu Chi Buddhist General Hospital Method for extracting antineoplastic components from bupleurum scorzonerifolium
US20050171167A1 (en) * 2003-11-04 2005-08-04 Haby Thomas A. Process and formulation containing epothilones and analogs thereof
US20090004277A1 (en) * 2004-05-18 2009-01-01 Franchini Miriam K Nanoparticle dispersion containing lactam compound
WO2006017761A2 (en) * 2004-08-05 2006-02-16 Emory University Epothilone analogues as therapeutic agents
EP1824458A1 (en) * 2004-11-18 2007-08-29 Bristol-Myers Squibb Company Enteric coated bead comprising epothilone or an epothilone analog, and preparation and administration thereof
BRPI0518286A2 (pt) * 2004-11-18 2008-11-11 Bristol Myers Squibb Co microesfera com revestimento entÉrico contendo ixabepilona e sua preparaÇço
EP1856255A4 (en) 2005-02-11 2010-01-27 Univ Southern California PROCESS FOR EXPRESSING PROTEINS VIA DISULPHIDE BRIDGES
EP2029156A4 (en) * 2006-05-01 2010-07-21 Univ Southern California COMBINATION THERAPY FOR CANCER TREATMENT
US8463852B2 (en) * 2006-10-06 2013-06-11 Oracle International Corporation Groupware portlets for integrating a portal with groupware systems
US8802394B2 (en) 2008-11-13 2014-08-12 Radu O. Minea Method of expressing proteins with disulfide bridges with enhanced yields and activity
CA2799202C (en) 2010-05-18 2016-07-05 Cerulean Pharma Inc. Compositions and methods for treatment of autoimmune and other diseases
BR112022013685A2 (pt) 2020-01-10 2022-09-06 R Pharm Us Operating Llc Composições de ixabepilona

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