JP2004520377A5 - - Google Patents

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Publication number
JP2004520377A5
JP2004520377A5 JP2002559400A JP2002559400A JP2004520377A5 JP 2004520377 A5 JP2004520377 A5 JP 2004520377A5 JP 2002559400 A JP2002559400 A JP 2002559400A JP 2002559400 A JP2002559400 A JP 2002559400A JP 2004520377 A5 JP2004520377 A5 JP 2004520377A5
Authority
JP
Japan
Prior art keywords
methyl
phenyl
thiazol
trifluoromethyl
sulfanyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002559400A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004520377A (ja
JP4234431B2 (ja
Filing date
Publication date
Priority claimed from GBGB0031103.5A external-priority patent/GB0031103D0/en
Application filed filed Critical
Publication of JP2004520377A publication Critical patent/JP2004520377A/ja
Publication of JP2004520377A5 publication Critical patent/JP2004520377A5/ja
Application granted granted Critical
Publication of JP4234431B2 publication Critical patent/JP4234431B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2002559400A 2000-12-20 2001-12-19 ヒトペルオキシソーム増殖因子活性化受容体の活性化剤としてのチアゾール及びオキサゾール誘導体 Expired - Fee Related JP4234431B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0031103.5A GB0031103D0 (en) 2000-12-20 2000-12-20 Chemical compounds
PCT/US2001/051056 WO2002059098A1 (en) 2000-12-20 2001-12-19 Thiazole and oxazole derivatives as activators of human peroxisome proliferator activated receptors

Publications (3)

Publication Number Publication Date
JP2004520377A JP2004520377A (ja) 2004-07-08
JP2004520377A5 true JP2004520377A5 (enExample) 2005-12-22
JP4234431B2 JP4234431B2 (ja) 2009-03-04

Family

ID=9905490

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002559400A Expired - Fee Related JP4234431B2 (ja) 2000-12-20 2001-12-19 ヒトペルオキシソーム増殖因子活性化受容体の活性化剤としてのチアゾール及びオキサゾール誘導体

Country Status (9)

Country Link
EP (1) EP1349843B1 (enExample)
JP (1) JP4234431B2 (enExample)
AT (1) ATE293611T1 (enExample)
DE (1) DE60110262T2 (enExample)
DK (1) DK1349843T3 (enExample)
ES (1) ES2240558T3 (enExample)
GB (1) GB0031103D0 (enExample)
PT (1) PT1349843E (enExample)
WO (1) WO2002059098A1 (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7041691B1 (en) 1999-06-30 2006-05-09 Amgen Inc. Compounds for the modulation of PPARγ activity
US20030171399A1 (en) 2000-06-28 2003-09-11 Tularik Inc. Quinolinyl and benzothiazolyl modulators
GB0031109D0 (en) 2000-12-20 2001-01-31 Glaxo Group Ltd Chemical compounds
US7105551B2 (en) 2000-12-20 2006-09-12 Smithkline Beecham Corporation Thiazole derivatives for treating PPAR related disorders
HRP20040098B1 (en) * 2001-08-13 2012-08-31 Janssen Pharmaceutica N.V. 2,4,5-TRlSUBSTITUTED THIAZOLYL DERIVATIVES AND THEIR ANTIINFLAMMATORY ACTIVITY
US7259175B2 (en) 2002-02-25 2007-08-21 Eli Lilly And Company Peroxisome proliferator activated receptor modulators
GB0214139D0 (en) 2002-06-19 2002-07-31 Glaxo Group Ltd Chemical compounds
CA2499380A1 (en) 2002-09-05 2004-03-18 Novo Nordisk A/S Novel vinyl carboxylic acid derivatives and their therapeutical use
JP2005035966A (ja) * 2002-09-06 2005-02-10 Takeda Chem Ind Ltd フランまたはチオフェン誘導体およびその医薬用途
US7553867B2 (en) 2002-09-06 2009-06-30 Takeda Pharmaceutical Company Limited Furan or thiophene derivative and medicinal use thereof
US20060052603A1 (en) * 2002-09-19 2006-03-09 Jiasheng Guo Process for preparing substituted phenoxy-acetic acids from phenols
KR20050061562A (ko) 2002-10-28 2005-06-22 노보 노르디스크 에이/에스 신규 화합물, 그들의 제제 및 사용
US20050080115A1 (en) 2002-10-28 2005-04-14 Lone Jeppesen Novel compounds, their preparation and use
US7129268B2 (en) 2002-10-28 2006-10-31 Novo Nordisk A/S Peroxisome proliferator activated receptor-active arylene acetic acid derivatives
DE60332860D1 (de) 2002-10-28 2010-07-15 High Point Pharmaceuticals Llc Neue verbindungen, die sich f r die behandlung von durch ppar vermittelten krankheiten eignen
DE10308355A1 (de) 2003-02-27 2004-12-23 Aventis Pharma Deutschland Gmbh Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
US7223761B2 (en) 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
WO2005105736A1 (en) 2004-05-05 2005-11-10 Novo Nordisk A/S Novel compounds, their preparation and use
ES2352085T3 (es) 2004-05-05 2011-02-15 High Point Pharmaceuticals, Llc Nuevos compuestos, su preparación y uso.
RU2007148439A (ru) * 2005-05-25 2009-06-27 Ниппон Кемифар Ко., Лтд. (JP) Активатор для рецептора, активируемого пролифератором пероксисом
ES2372617T3 (es) 2005-06-30 2012-01-24 High Point Pharmaceuticals, Llc Ácidos fenoxiacéticos como activadores de ppar-delta.
EA201101085A1 (ru) 2005-12-22 2012-05-30 ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи Феноксиуксусные кислоты в качестве активаторов ppar дельта
JP2009132620A (ja) * 2006-03-07 2009-06-18 Astellas Pharma Inc フェニルチアゾール誘導体
EP1999098A2 (en) 2006-03-09 2008-12-10 High Point Pharmaceuticals, LLC Compounds that modulate ppar activity, their preparation and use
EP2014652B1 (en) 2006-04-18 2014-08-06 Nippon Chemiphar Co., Ltd. Activating agent for peroxisome proliferator activated receptor
MEP8509A (en) 2006-09-07 2011-12-20 Combination treatment for diabetes mellitus
FR2910893A1 (fr) * 2006-12-29 2008-07-04 Genfit Sa Derives de (phenylthiazolyl)-phenyl-propan-1-one et de (phenyloxazolyl)-phenyl-propan-1-one substitues, preparations et utilisations.
PT2152663E (pt) 2007-06-04 2014-06-03 Univ Ben Gurion Compostos de triarilo e composições que compreendem os mesmos
MX2010011252A (es) 2008-04-15 2010-11-30 Nippon Chemiphar Co Activador para el receptor activado por el proliferador de peroxisoma.
US20120094959A1 (en) 2010-10-19 2012-04-19 Bonnie Blazer-Yost Treatment of cystic diseases
WO2012122368A1 (en) * 2011-03-08 2012-09-13 The Regents Of The University Of California Deoxycytidine kinase binding compounds
WO2015035171A1 (en) 2013-09-09 2015-03-12 High Point Pharmaceuticals, Llc Use of a ppar-delta agonist for treating muscle atrophy
EP3065723B1 (en) 2013-11-05 2020-09-23 Ben Gurion University of the Negev Research and Development Authority Compounds for the treatment of diabetes and disease complications arising from same
AU2020405068A1 (en) 2019-12-18 2022-07-07 Stinginn Llc Substituted 1,2, 4-triazoles and methods of use
PE20231656A1 (es) 2020-11-02 2023-10-17 Trethera Corp Formas cristalinas de un inhibidor de cinasa de desoxicitidina y sus usos
CA3217437A1 (en) * 2021-05-19 2022-11-24 Glen Barber Small molecular inhibitors of sting signaling compositions and methods of use
WO2023147309A1 (en) 2022-01-25 2023-08-03 Reneo Pharmaceuticals, Inc. Use of ppar-delta agonists in the treatment of disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0788353A1 (en) * 1995-09-18 1997-08-13 Ligand Pharmaceuticals, Inc. Ppar gamma antagonists for treating obesity
GB9817118D0 (en) * 1998-08-07 1998-10-07 Glaxo Group Ltd Pharmaceutical compounds
GB9914977D0 (en) * 1999-06-25 1999-08-25 Glaxo Group Ltd Chemical compounds
PE20011010A1 (es) * 1999-12-02 2001-10-18 Glaxo Group Ltd Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano

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