JP2005534672A5 - - Google Patents
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- Publication number
- JP2005534672A5 JP2005534672A5 JP2004514761A JP2004514761A JP2005534672A5 JP 2005534672 A5 JP2005534672 A5 JP 2005534672A5 JP 2004514761 A JP2004514761 A JP 2004514761A JP 2004514761 A JP2004514761 A JP 2004514761A JP 2005534672 A5 JP2005534672 A5 JP 2005534672A5
- Authority
- JP
- Japan
- Prior art keywords
- oxy
- phenyl
- pyridinyl
- acetic acid
- pentyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0214149.7A GB0214149D0 (en) | 2002-06-19 | 2002-06-19 | Chemical compounds |
| PCT/EP2003/006415 WO2004000315A1 (en) | 2002-06-19 | 2003-06-18 | Phenylalkanoic acid and phenyloxyalkanoic acid derivatives as hppar activators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005534672A JP2005534672A (ja) | 2005-11-17 |
| JP2005534672A5 true JP2005534672A5 (enExample) | 2006-06-15 |
Family
ID=9938916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004514761A Pending JP2005534672A (ja) | 2002-06-19 | 2003-06-18 | ｈＰＰＡＲ活性化物質としてのフェニルアルカン酸及びフェニルオキシアルカン酸誘導体 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7338960B2 (enExample) |
| EP (1) | EP1513526B1 (enExample) |
| JP (1) | JP2005534672A (enExample) |
| KR (1) | KR20050030624A (enExample) |
| CN (1) | CN1674897A (enExample) |
| AT (1) | ATE377420T1 (enExample) |
| AU (1) | AU2003245962B2 (enExample) |
| BR (1) | BR0311931A (enExample) |
| CA (1) | CA2487909A1 (enExample) |
| CY (1) | CY1107168T1 (enExample) |
| DE (1) | DE60317326T2 (enExample) |
| DK (1) | DK1513526T3 (enExample) |
| ES (1) | ES2295601T3 (enExample) |
| GB (1) | GB0214149D0 (enExample) |
| IL (1) | IL165476A0 (enExample) |
| IS (1) | IS7574A (enExample) |
| MX (1) | MXPA04012857A (enExample) |
| NO (1) | NO20045328L (enExample) |
| NZ (1) | NZ537210A (enExample) |
| PL (1) | PL375148A1 (enExample) |
| PT (1) | PT1513526E (enExample) |
| RU (1) | RU2323929C2 (enExample) |
| SI (1) | SI1513526T1 (enExample) |
| WO (1) | WO2004000315A1 (enExample) |
| ZA (1) | ZA200410061B (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7244763B2 (en) | 2003-04-17 | 2007-07-17 | Warner Lambert Company Llc | Compounds that modulate PPAR activity and methods of preparation |
| PL1667964T3 (pl) | 2003-09-19 | 2010-01-29 | Janssen Pharmaceutica Nv | Kwasy 4-((fenoksyalkilo)tio)-fenoksyoctowe i analogi |
| NZ546444A (en) | 2003-11-05 | 2009-09-25 | Hoffmann La Roche | Phenyl derivatives as PPAR agonists |
| RU2006126978A (ru) * | 2003-12-25 | 2008-01-27 | Такеда Фармасьютикал Компани Лимитед (Jp) | Производные 3-(4-бензилоксифенил)пропановой кислоты |
| KR20070004769A (ko) * | 2004-02-27 | 2007-01-09 | 암젠 인코포레이션 | 대사 장애의 치료에 사용되는 화합물, 약제학적 조성물 및그 사용방법 |
| AR048523A1 (es) * | 2004-04-07 | 2006-05-03 | Kalypsys Inc | Compuestos con estructura de aril sulfonamida y sulfonilo como moduladores de ppar y metodos para tratar trastornos metabolicos |
| EP1745003B1 (en) | 2004-05-05 | 2010-10-27 | High Point Pharmaceuticals, LLC | Novel compounds, their preparation and use |
| JP4981662B2 (ja) | 2004-05-05 | 2012-07-25 | ハイ・ポイント・ファーマスーティカルズ、エルエルシー | 新規の化合物、その製法と使用 |
| MY147518A (en) | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| US7465804B2 (en) | 2005-05-20 | 2008-12-16 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders |
| RU2412935C2 (ru) | 2005-06-30 | 2011-02-27 | Хай Пойнт Фармасьютикалс, ЛЛС | Феноксиуксусные кислоты в качестве активаторов дельта рецепторов ppar |
| EP1924546A1 (en) * | 2005-09-14 | 2008-05-28 | Amgen, Inc | Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders |
| JO3006B1 (ar) | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
| EA201101084A1 (ru) | 2005-12-22 | 2012-04-30 | ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Феноксиуксусные кислоты в качестве активаторов ppar дельта |
| US7943612B2 (en) | 2006-03-09 | 2011-05-17 | High Point Pharmaceuticals, Llc | Compounds that modulate PPAR activity, their preparation and use |
| EP2001844A2 (en) * | 2006-03-14 | 2008-12-17 | Amgen, Inc | Bicyclic carboxylic acid derivatives useful for treating metabolic disorders |
| PE20080188A1 (es) | 2006-04-18 | 2008-03-10 | Janssen Pharmaceutica Nv | Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol |
| CN101591227B (zh) * | 2006-06-23 | 2012-09-05 | 赵昱 | 一类肉桂醇类衍生物及其制备方法和药物用途 |
| EP2061760A1 (en) * | 2006-09-07 | 2009-05-27 | Amgen, Inc | Benzo-fused compounds for use in treating metabolic disorders |
| US7714008B2 (en) | 2006-09-07 | 2010-05-11 | Amgen Inc. | Heterocyclic GPR40 modulators |
| AU2007326114B2 (en) * | 2006-12-02 | 2011-08-25 | Seoul National University Industry Foundation | Aryl compounds as PPAR ligands and their use |
| CA2683751C (en) * | 2007-04-16 | 2013-01-08 | Amgen Inc. | Substituted biphenyl phenoxy-, thiophenyl- and aminophenylpropanoic acid gpr40 modulators |
| US8759355B2 (en) * | 2007-07-25 | 2014-06-24 | Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. | Aryl pyrimidine derivatives, preparation methods and pharmaceutical uses thereof |
| MX2010003876A (es) | 2007-10-10 | 2010-12-02 | Amgen Inc | Moduladores de gpr40 bifenilo- sustituidos. |
| EP2260017A1 (en) * | 2008-03-06 | 2010-12-15 | Amgen, Inc | Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders |
| AU2009303475B2 (en) | 2008-10-15 | 2012-09-13 | Amgen Inc. | Spirocyclic GPR40 modulators |
| EP2699569B1 (en) * | 2011-04-22 | 2017-08-30 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
| WO2013128378A1 (en) | 2012-02-28 | 2013-09-06 | Piramal Enterprises Limited | Phenyl alkanoic acid derivatives as gpr agonists |
| KR101569522B1 (ko) | 2013-04-18 | 2015-11-17 | 현대약품 주식회사 | 신규한 3-(4-(벤질옥시)페닐)헥스-4-이노익 산 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 대사성 질환의 예방 또는 치료용 약학적 조성물 |
| EP3756661A1 (en) | 2013-09-09 | 2020-12-30 | vTv Therapeutics LLC | Use of a ppar-delta agonist for treating muscle atrophy |
| CN108503581A (zh) * | 2018-04-12 | 2018-09-07 | 苏州康润医药有限公司 | 一种3-溴-6-氟-2-吡啶乙酮的合成方法 |
| WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS175831B1 (enExample) * | 1974-12-17 | 1977-05-31 | ||
| FR2401459A1 (fr) * | 1977-08-26 | 1979-03-23 | Cii Honeywell Bull | Support d'information portatif muni d'un microprocesseur et d'une memoire morte programmable |
| DE4038335A1 (de) * | 1990-12-01 | 1992-06-04 | Boehringer Mannheim Gmbh | Neue pyridinderivate, verfahren zu ihrer herstellung und verwendung als arzneimittel |
| GB9604242D0 (en) * | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| CA2263721A1 (en) * | 1996-08-19 | 1998-02-26 | Satoshi Ohrui | Propionic acid derivatives and applications thereof |
| AU8750298A (en) * | 1997-08-28 | 1999-03-22 | Ono Pharmaceutical Co. Ltd. | Peroxisome proliferator-activated receptor controllers |
| US6506757B1 (en) * | 1998-03-10 | 2003-01-14 | Ono Pharmaceutical Co., Ltd. | Carboxylic acid derivatives and drugs containing the same as the active ingredient |
| US6586475B1 (en) * | 1998-11-20 | 2003-07-01 | Takeda Chemical Industries, Ltd. | β-amyloid protein production/secretion inhibitors |
| EE200100558A (et) * | 1999-04-28 | 2002-12-16 | Aventis Pharma Deutschland Gmbh | Triarüülhappe derivaat, seda sisaldav farmatseutiline kompositsioon ja ühendi raviotstarbeline kasutamine |
| AU1624801A (en) * | 1999-11-19 | 2001-05-30 | Corvas International, Inc. | Plasminogen activator inhibitor antagonists related applications |
| AU2001258771A1 (en) * | 2000-05-19 | 2001-11-26 | Takeda Chemical Industries Ltd. | -secretase inhibitors |
-
2002
- 2002-06-19 GB GBGB0214149.7A patent/GB0214149D0/en not_active Ceased
-
2003
- 2003-06-18 BR BR0311931-9A patent/BR0311931A/pt not_active IP Right Cessation
- 2003-06-18 NZ NZ537210A patent/NZ537210A/en unknown
- 2003-06-18 JP JP2004514761A patent/JP2005534672A/ja active Pending
- 2003-06-18 CA CA002487909A patent/CA2487909A1/en not_active Abandoned
- 2003-06-18 PL PL03375148A patent/PL375148A1/xx not_active Application Discontinuation
- 2003-06-18 WO PCT/EP2003/006415 patent/WO2004000315A1/en not_active Ceased
- 2003-06-18 DK DK03738056T patent/DK1513526T3/da active
- 2003-06-18 US US10/518,679 patent/US7338960B2/en not_active Expired - Fee Related
- 2003-06-18 ES ES03738056T patent/ES2295601T3/es not_active Expired - Lifetime
- 2003-06-18 CN CNA03819290XA patent/CN1674897A/zh active Pending
- 2003-06-18 RU RU2004135539/04A patent/RU2323929C2/ru not_active IP Right Cessation
- 2003-06-18 AU AU2003245962A patent/AU2003245962B2/en not_active Ceased
- 2003-06-18 KR KR1020047020583A patent/KR20050030624A/ko not_active Ceased
- 2003-06-18 IL IL16547603A patent/IL165476A0/xx unknown
- 2003-06-18 DE DE60317326T patent/DE60317326T2/de not_active Expired - Fee Related
- 2003-06-18 EP EP03738056A patent/EP1513526B1/en not_active Expired - Lifetime
- 2003-06-18 PT PT03738056T patent/PT1513526E/pt unknown
- 2003-06-18 AT AT03738056T patent/ATE377420T1/de not_active IP Right Cessation
- 2003-06-18 MX MXPA04012857A patent/MXPA04012857A/es active IP Right Grant
- 2003-06-18 SI SI200331089T patent/SI1513526T1/sl unknown
-
2004
- 2004-11-30 IS IS7574A patent/IS7574A/is unknown
- 2004-12-03 NO NO20045328A patent/NO20045328L/no not_active Application Discontinuation
- 2004-12-13 ZA ZA200410061A patent/ZA200410061B/en unknown
-
2008
- 2008-01-31 CY CY20081100116T patent/CY1107168T1/el unknown
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