JP2005534672A5 - - Google Patents
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- Publication number
- JP2005534672A5 JP2005534672A5 JP2004514761A JP2004514761A JP2005534672A5 JP 2005534672 A5 JP2005534672 A5 JP 2005534672A5 JP 2004514761 A JP2004514761 A JP 2004514761A JP 2004514761 A JP2004514761 A JP 2004514761A JP 2005534672 A5 JP2005534672 A5 JP 2005534672A5
- Authority
- JP
- Japan
- Prior art keywords
- oxy
- phenyl
- pyridinyl
- acetic acid
- pentyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0214149.7A GB0214149D0 (en) | 2002-06-19 | 2002-06-19 | Chemical compounds |
| PCT/EP2003/006415 WO2004000315A1 (en) | 2002-06-19 | 2003-06-18 | Phenylalkanoic acid and phenyloxyalkanoic acid derivatives as hppar activators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005534672A JP2005534672A (ja) | 2005-11-17 |
| JP2005534672A5 true JP2005534672A5 (enExample) | 2006-06-15 |
Family
ID=9938916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004514761A Pending JP2005534672A (ja) | 2002-06-19 | 2003-06-18 | ｈＰＰＡＲ活性化物質としてのフェニルアルカン酸及びフェニルオキシアルカン酸誘導体 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7338960B2 (enExample) |
| EP (1) | EP1513526B1 (enExample) |
| JP (1) | JP2005534672A (enExample) |
| KR (1) | KR20050030624A (enExample) |
| CN (1) | CN1674897A (enExample) |
| AT (1) | ATE377420T1 (enExample) |
| AU (1) | AU2003245962B2 (enExample) |
| BR (1) | BR0311931A (enExample) |
| CA (1) | CA2487909A1 (enExample) |
| CY (1) | CY1107168T1 (enExample) |
| DE (1) | DE60317326T2 (enExample) |
| DK (1) | DK1513526T3 (enExample) |
| ES (1) | ES2295601T3 (enExample) |
| GB (1) | GB0214149D0 (enExample) |
| IL (1) | IL165476A0 (enExample) |
| IS (1) | IS7574A (enExample) |
| MX (1) | MXPA04012857A (enExample) |
| NO (1) | NO20045328L (enExample) |
| NZ (1) | NZ537210A (enExample) |
| PL (1) | PL375148A1 (enExample) |
| PT (1) | PT1513526E (enExample) |
| RU (1) | RU2323929C2 (enExample) |
| SI (1) | SI1513526T1 (enExample) |
| WO (1) | WO2004000315A1 (enExample) |
| ZA (1) | ZA200410061B (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7244763B2 (en) | 2003-04-17 | 2007-07-17 | Warner Lambert Company Llc | Compounds that modulate PPAR activity and methods of preparation |
| UA87467C2 (xx) | 2003-09-19 | 2009-07-27 | Янссен Фармацевтика Н.В | 4-((феноксіалкіл)тіо)феноксіоцтова кислота та її аналоги$4-((феноксиалкил)тио)феноксиуксусная кислота и ее аналоги |
| RU2374230C2 (ru) | 2003-11-05 | 2009-11-27 | Ф.Хоффманн-Ля Рош Аг | Фенильные производные в качестве ppar агонистов |
| US7456218B2 (en) | 2003-12-25 | 2008-11-25 | Takeda Pharmaceutical Company Limited | 3-(4-benzyloxyphenyl) propanoic acid derivatives |
| EP1737809B1 (en) * | 2004-02-27 | 2013-09-18 | Amgen, Inc | Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders |
| AR048523A1 (es) * | 2004-04-07 | 2006-05-03 | Kalypsys Inc | Compuestos con estructura de aril sulfonamida y sulfonilo como moduladores de ppar y metodos para tratar trastornos metabolicos |
| WO2005105736A1 (en) | 2004-05-05 | 2005-11-10 | Novo Nordisk A/S | Novel compounds, their preparation and use |
| ES2352085T3 (es) | 2004-05-05 | 2011-02-15 | High Point Pharmaceuticals, Llc | Nuevos compuestos, su preparación y uso. |
| MY147518A (en) * | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| US7465804B2 (en) | 2005-05-20 | 2008-12-16 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders |
| ES2372617T3 (es) | 2005-06-30 | 2012-01-24 | High Point Pharmaceuticals, Llc | Ácidos fenoxiacéticos como activadores de ppar-delta. |
| JO3006B1 (ar) | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
| US7582803B2 (en) * | 2005-09-14 | 2009-09-01 | Amgen Inc. | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders |
| EA201101085A1 (ru) | 2005-12-22 | 2012-05-30 | ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Феноксиуксусные кислоты в качестве активаторов ppar дельта |
| EP1999098A2 (en) | 2006-03-09 | 2008-12-10 | High Point Pharmaceuticals, LLC | Compounds that modulate ppar activity, their preparation and use |
| AU2007225208A1 (en) * | 2006-03-14 | 2007-09-20 | Amgen Inc. | Bicyclic carboxylic acid derivatives useful for treating metabolic disorders |
| PE20080188A1 (es) | 2006-04-18 | 2008-03-10 | Janssen Pharmaceutica Nv | Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol |
| CN101591227B (zh) * | 2006-06-23 | 2012-09-05 | 赵昱 | 一类肉桂醇类衍生物及其制备方法和药物用途 |
| CA2662305C (en) | 2006-09-07 | 2012-04-17 | Amgen Inc. | Heterocyclic gpr40 modulators |
| EP2061760A1 (en) * | 2006-09-07 | 2009-05-27 | Amgen, Inc | Benzo-fused compounds for use in treating metabolic disorders |
| US8519145B2 (en) | 2006-12-02 | 2013-08-27 | Seoul National University Industry Foundation | Aryl compounds as PPAR ligands and their use |
| ES2446419T3 (es) * | 2007-04-16 | 2014-03-07 | Amgen, Inc | Moduladores de GPR40 de ácidos bifenilfenoxi, tiofenil y aminofenilpropanoico sustituidos |
| EP2184277B1 (en) * | 2007-07-25 | 2015-07-01 | Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China | Aryl pyrimidine derivatives, preparation methods and pharmaceutical uses thereof |
| JP5591706B2 (ja) | 2007-10-10 | 2014-09-17 | アムジエン・インコーポレーテツド | 置換ビフェニルｇｐｒ４０調節因子 |
| WO2009111056A1 (en) | 2008-03-06 | 2009-09-11 | Amgen Inc. | Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders |
| AU2009303475B2 (en) | 2008-10-15 | 2012-09-13 | Amgen Inc. | Spirocyclic GPR40 modulators |
| WO2012145617A2 (en) * | 2011-04-22 | 2012-10-26 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
| TW201341356A (zh) | 2012-02-28 | 2013-10-16 | 皮拉馬爾企業有限公司 | 作為gpr促效劑之苯基烷酸衍生物 |
| KR101569522B1 (ko) | 2013-04-18 | 2015-11-17 | 현대약품 주식회사 | 신규한 3-(4-(벤질옥시)페닐)헥스-4-이노익 산 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 대사성 질환의 예방 또는 치료용 약학적 조성물 |
| WO2015035171A1 (en) | 2013-09-09 | 2015-03-12 | High Point Pharmaceuticals, Llc | Use of a ppar-delta agonist for treating muscle atrophy |
| CN108503581A (zh) * | 2018-04-12 | 2018-09-07 | 苏州康润医药有限公司 | 一种3-溴-6-氟-2-吡啶乙酮的合成方法 |
| WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS175831B1 (enExample) * | 1974-12-17 | 1977-05-31 | ||
| FR2401459A1 (fr) * | 1977-08-26 | 1979-03-23 | Cii Honeywell Bull | Support d'information portatif muni d'un microprocesseur et d'une memoire morte programmable |
| DE4038335A1 (de) * | 1990-12-01 | 1992-06-04 | Boehringer Mannheim Gmbh | Neue pyridinderivate, verfahren zu ihrer herstellung und verwendung als arzneimittel |
| GB9604242D0 (en) * | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| RU2174121C2 (ru) * | 1996-08-19 | 2001-09-27 | Джапан Тобакко Инк. | Производные пропионовой кислоты и фармацевтическая композиция на их основе |
| AU8750298A (en) * | 1997-08-28 | 1999-03-22 | Ono Pharmaceutical Co. Ltd. | Peroxisome proliferator-activated receptor controllers |
| DE69941777D1 (de) * | 1998-03-10 | 2010-01-21 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| US6586475B1 (en) * | 1998-11-20 | 2003-07-01 | Takeda Chemical Industries, Ltd. | β-amyloid protein production/secretion inhibitors |
| NZ515087A (en) * | 1999-04-28 | 2003-11-28 | Aventis Pharma Gmbh | Tri-aryl acid derivatives as PPAR receptor ligands |
| WO2001036351A2 (en) * | 1999-11-19 | 2001-05-25 | Corvas International, Inc. | Plasminogen activator inhibitor antagonists related applications |
| AU2001258771A1 (en) * | 2000-05-19 | 2001-11-26 | Takeda Chemical Industries Ltd. | -secretase inhibitors |
-
2002
- 2002-06-19 GB GBGB0214149.7A patent/GB0214149D0/en not_active Ceased
-
2003
- 2003-06-18 NZ NZ537210A patent/NZ537210A/en unknown
- 2003-06-18 PL PL03375148A patent/PL375148A1/xx not_active Application Discontinuation
- 2003-06-18 AT AT03738056T patent/ATE377420T1/de not_active IP Right Cessation
- 2003-06-18 MX MXPA04012857A patent/MXPA04012857A/es active IP Right Grant
- 2003-06-18 CA CA002487909A patent/CA2487909A1/en not_active Abandoned
- 2003-06-18 DK DK03738056T patent/DK1513526T3/da active
- 2003-06-18 KR KR1020047020583A patent/KR20050030624A/ko not_active Ceased
- 2003-06-18 CN CNA03819290XA patent/CN1674897A/zh active Pending
- 2003-06-18 JP JP2004514761A patent/JP2005534672A/ja active Pending
- 2003-06-18 BR BR0311931-9A patent/BR0311931A/pt not_active IP Right Cessation
- 2003-06-18 RU RU2004135539/04A patent/RU2323929C2/ru not_active IP Right Cessation
- 2003-06-18 ES ES03738056T patent/ES2295601T3/es not_active Expired - Lifetime
- 2003-06-18 EP EP03738056A patent/EP1513526B1/en not_active Expired - Lifetime
- 2003-06-18 AU AU2003245962A patent/AU2003245962B2/en not_active Ceased
- 2003-06-18 US US10/518,679 patent/US7338960B2/en not_active Expired - Fee Related
- 2003-06-18 SI SI200331089T patent/SI1513526T1/sl unknown
- 2003-06-18 IL IL16547603A patent/IL165476A0/xx unknown
- 2003-06-18 PT PT03738056T patent/PT1513526E/pt unknown
- 2003-06-18 DE DE60317326T patent/DE60317326T2/de not_active Expired - Fee Related
- 2003-06-18 WO PCT/EP2003/006415 patent/WO2004000315A1/en not_active Ceased
-
2004
- 2004-11-30 IS IS7574A patent/IS7574A/is unknown
- 2004-12-03 NO NO20045328A patent/NO20045328L/no not_active Application Discontinuation
- 2004-12-13 ZA ZA200410061A patent/ZA200410061B/en unknown
-
2008
- 2008-01-31 CY CY20081100116T patent/CY1107168T1/el unknown
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