JP2004517088A5 - - Google Patents
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- Publication number
- JP2004517088A5 JP2004517088A5 JP2002547917A JP2002547917A JP2004517088A5 JP 2004517088 A5 JP2004517088 A5 JP 2004517088A5 JP 2002547917 A JP2002547917 A JP 2002547917A JP 2002547917 A JP2002547917 A JP 2002547917A JP 2004517088 A5 JP2004517088 A5 JP 2004517088A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- compound according
- alkyl
- carbonitrile
- methanesulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25128300P | 2000-12-05 | 2000-12-05 | |
| PCT/EP2001/013716 WO2002046178A2 (en) | 2000-12-05 | 2001-11-26 | Benzofuran and benzothiophene derivatives as selective cox-2 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004517088A JP2004517088A (ja) | 2004-06-10 |
| JP2004517088A5 true JP2004517088A5 (enExample) | 2005-12-22 |
| JP4212892B2 JP4212892B2 (ja) | 2009-01-21 |
Family
ID=22951260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002547917A Expired - Fee Related JP4212892B2 (ja) | 2000-12-05 | 2001-11-26 | ベンゾフラン及びベンゾチオフェン誘導体 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6433005B1 (enExample) |
| EP (1) | EP1347963B1 (enExample) |
| JP (1) | JP4212892B2 (enExample) |
| KR (1) | KR20030070054A (enExample) |
| CN (1) | CN1273460C (enExample) |
| AR (1) | AR035719A1 (enExample) |
| AT (1) | ATE274507T1 (enExample) |
| AU (2) | AU2002224890B2 (enExample) |
| BR (1) | BR0115963A (enExample) |
| CA (1) | CA2437048A1 (enExample) |
| DE (1) | DE60105195T2 (enExample) |
| ES (1) | ES2225641T3 (enExample) |
| MX (1) | MXPA03004398A (enExample) |
| PT (1) | PT1347963E (enExample) |
| WO (1) | WO2002046178A2 (enExample) |
| ZA (1) | ZA200303641B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999051587A1 (en) * | 1998-04-01 | 1999-10-14 | Ono Pharmaceutical Co., Ltd. | Fused thiophene derivatives and drugs containing the same as the active ingredient |
| JP2001261674A (ja) * | 2000-03-22 | 2001-09-26 | Mitsui Chemicals Inc | ベンゾチオフェン誘導体およびそれを有効成分として含有する核内レセプター作動薬 |
| AU5878001A (en) * | 2000-05-18 | 2001-11-26 | Daiichi Pharmaceutical Co., Ltd. | Novel benzothiophene derivatives |
| AU2001268051A1 (en) * | 2000-06-28 | 2002-01-08 | Eli Lilly And Company | Spla2 inhibitors |
| US7071220B2 (en) * | 2000-09-18 | 2006-07-04 | Toa Eiyo Ltd. | N-substituted benzothiophenesulfonamide derivatives |
| WO2005033112A2 (en) * | 2003-10-02 | 2005-04-14 | Cephalon, Inc. | Substituted indole derivatives |
| ATE555091T1 (de) | 2006-02-03 | 2012-05-15 | Bionomics Ltd | Substituierte benzofurane, benzothiophene, benzoselenophene und indole und ihre verwendung als tubulinpolymerisationsinhibitoren |
| WO2008055808A1 (en) | 2006-11-09 | 2008-05-15 | F. Hoffmann-La Roche Ag | Indole and benzofuran 2-carboxamide derivatives |
| AU2011202542A1 (en) | 2010-07-14 | 2012-02-02 | Indian Institute Of Science | Benzothiophene carboxamide compounds, composition and applications thereof |
| CN103819371B (zh) * | 2012-11-16 | 2016-05-04 | 中国科学院大连化学物理研究所 | 一种对甲砜基苯甲醛的合成方法 |
| CN103058988B (zh) * | 2012-12-31 | 2015-09-02 | 中国人民大学 | 苯并噻吩及其衍生物及其制备方法与应用 |
| CN110903225B (zh) * | 2019-12-11 | 2021-11-09 | 苏州开元民生科技股份有限公司 | 一种对甲砜基苯甲醛的合成方法 |
| CN114456136B (zh) * | 2022-01-27 | 2024-06-07 | 广西中医药大学 | 双靶点非甾体抗炎化合物及其制备方法与用途 |
| KR102542698B1 (ko) * | 2022-04-05 | 2023-06-14 | 주식회사 베노바이오 | 신규한 벤조사이오펜 유도체 및 bet 억제제로서의 용도 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3331854A (en) * | 1964-12-14 | 1967-07-18 | American Cyanamid Co | Novel furan and thiophene compounds |
| US4663347A (en) | 1983-10-31 | 1987-05-05 | Merck Frosst Canada, Inc. | Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis |
| US4745127A (en) * | 1983-10-31 | 1988-05-17 | Merck Frosst Canada, Inc. | Benzyl esters of benzofuran-2-carboxylic acids useful as inhibitors of leukotriene biosynthesis |
| US4822803A (en) | 1983-10-31 | 1989-04-18 | Merck Frosst Canada, Inc. | Benzofuran 2-carboxylic acid hydrazides useful as inhibitors of leukotriene biosynthesis |
| US4933351A (en) | 1983-10-31 | 1990-06-12 | Merck Frosst Canada, Inc. | Benzofuran 2-carbox amides useful as inhibitors of leukoriene biosynthesis |
| DE3342624A1 (de) | 1983-11-25 | 1984-03-29 | Heinfried Dr. 4019 Monheim Grote | Benzaronderivate, verfahren zu ihrer herstellung und diese derivate enthaltende arzneimittel |
| US4621091A (en) | 1984-10-09 | 1986-11-04 | Merck & Co., Inc. | 3-hydroxybenzo[b]thiophene-2-sulfide derivatives compositions, and method of use therefor |
| US5208253A (en) * | 1992-02-24 | 1993-05-04 | Warner-Lambert Company | 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo(b) thiophene-2-carboxamides as inhibitors of cell adhesion |
| WO1995002406A2 (en) | 1993-07-15 | 1995-01-26 | Warner-Lambert Company | Use of benzothiophenes and benzofurans for the treatment of inflammatory bowel disease and inflammation assay method |
| US5426113A (en) | 1994-04-08 | 1995-06-20 | Warner-Lambert Company | Method of preventing ulcer formation caused by nonsteroidal antiinflammatory drugs employing tetrazol-benzothiophene carboxamide compounds |
| US5521213A (en) * | 1994-08-29 | 1996-05-28 | Merck Frosst Canada, Inc. | Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2 |
| CN1211921A (zh) * | 1996-02-22 | 1999-03-24 | 伊莱利利公司 | 苯并噻吩、含有它们的制剂及其制备方法 |
| US5731342A (en) | 1996-02-22 | 1998-03-24 | Eli Lilly And Company | Benzothiophenes, formulations containing same, and methods |
-
2001
- 2001-11-26 KR KR10-2003-7007600A patent/KR20030070054A/ko not_active Abandoned
- 2001-11-26 MX MXPA03004398A patent/MXPA03004398A/es active IP Right Grant
- 2001-11-26 PT PT01994723T patent/PT1347963E/pt unknown
- 2001-11-26 DE DE60105195T patent/DE60105195T2/de not_active Expired - Fee Related
- 2001-11-26 AT AT01994723T patent/ATE274507T1/de not_active IP Right Cessation
- 2001-11-26 CA CA002437048A patent/CA2437048A1/en not_active Abandoned
- 2001-11-26 WO PCT/EP2001/013716 patent/WO2002046178A2/en not_active Ceased
- 2001-11-26 AU AU2002224890A patent/AU2002224890B2/en not_active Ceased
- 2001-11-26 BR BR0115963-1A patent/BR0115963A/pt not_active IP Right Cessation
- 2001-11-26 ES ES01994723T patent/ES2225641T3/es not_active Expired - Lifetime
- 2001-11-26 JP JP2002547917A patent/JP4212892B2/ja not_active Expired - Fee Related
- 2001-11-26 CN CNB01820077XA patent/CN1273460C/zh not_active Expired - Fee Related
- 2001-11-26 AU AU2489002A patent/AU2489002A/xx active Pending
- 2001-11-26 EP EP01994723A patent/EP1347963B1/en not_active Expired - Lifetime
- 2001-12-03 US US10/006,349 patent/US6433005B1/en not_active Expired - Fee Related
- 2001-12-03 AR ARP010105603A patent/AR035719A1/es not_active Application Discontinuation
-
2003
- 2003-05-12 ZA ZA200303641A patent/ZA200303641B/en unknown
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