JP2009084270A5 - - Google Patents
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- Publication number
- JP2009084270A5 JP2009084270A5 JP2008225403A JP2008225403A JP2009084270A5 JP 2009084270 A5 JP2009084270 A5 JP 2009084270A5 JP 2008225403 A JP2008225403 A JP 2008225403A JP 2008225403 A JP2008225403 A JP 2008225403A JP 2009084270 A5 JP2009084270 A5 JP 2009084270A5
- Authority
- JP
- Japan
- Prior art keywords
- xinafoate
- xinafoate salt
- disease
- indicated
- dry powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97003007P | 2007-09-05 | 2007-09-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009084270A JP2009084270A (ja) | 2009-04-23 |
| JP2009084270A5 true JP2009084270A5 (enExample) | 2011-10-06 |
Family
ID=40293576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008225403A Pending JP2009084270A (ja) | 2007-09-05 | 2008-09-03 | 塩形態 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US8193181B2 (enExample) |
| EP (1) | EP2215087B1 (enExample) |
| JP (1) | JP2009084270A (enExample) |
| KR (2) | KR101225233B1 (enExample) |
| CN (1) | CN101861314B (enExample) |
| AR (1) | AR068369A1 (enExample) |
| AU (1) | AU2008294473B2 (enExample) |
| BR (1) | BRPI0816278A2 (enExample) |
| CA (1) | CA2697495C (enExample) |
| ES (1) | ES2452965T3 (enExample) |
| IL (1) | IL203973A (enExample) |
| MX (1) | MX2010002518A (enExample) |
| NZ (1) | NZ583582A (enExample) |
| RU (1) | RU2458925C2 (enExample) |
| TW (1) | TWI371277B (enExample) |
| WO (1) | WO2009031011A2 (enExample) |
| ZA (1) | ZA201002356B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0908772D0 (en) * | 2009-05-21 | 2009-07-01 | Astrazeneca Ab | New salts 756 |
| AU2010250923A1 (en) | 2009-05-21 | 2011-11-17 | Astrazeneca Ab | Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases |
| AU2012253885A1 (en) | 2011-05-10 | 2013-10-31 | Merck Sharp & Dohme Corp. | Aminopyrimidines as Syk inhibitors |
| CA2834062A1 (en) | 2011-05-10 | 2012-11-15 | Merck Sharp & Dohme Corp. | Pyridyl aminopyridines as syk inhibitors |
| WO2012154518A1 (en) | 2011-05-10 | 2012-11-15 | Merck Sharp & Dohme Corp. | Bipyridylaminopyridines as syk inhibitors |
| US8987456B2 (en) | 2011-10-05 | 2015-03-24 | Merck Sharp & Dohme Corp. | 3-pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors |
| WO2013052391A1 (en) | 2011-10-05 | 2013-04-11 | Merck Sharp & Dohme Corp. | PHENYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (Syk) INHIBITORS |
| EP2763976B1 (en) | 2011-10-05 | 2016-05-18 | Merck Sharp & Dohme Corp. | 2-pyridyl carboxamide-containing spleen tyrosine kinase (syk) inhibitors |
| EP2768480A1 (en) * | 2011-10-21 | 2014-08-27 | Rigel Pharmaceuticals, Inc. | Method and device for administering xinafoate salt of n4-(2,2-difluoro-4h-benzo [1,4]oxazin-3-one) -6-yl]-5-fluoro-n2- [3- (methylaminocarbonylmethyleneoxy) phenyl]2,4-pyrimidinediamine |
| EP2863913B1 (en) | 2012-06-20 | 2018-09-12 | Merck Sharp & Dohme Corp. | Imidazolyl analogs as syk inhibitors |
| WO2013192125A1 (en) | 2012-06-20 | 2013-12-27 | Merck Sharp & Dohme Corp. | Pyrazolyl derivatives as syk inhibitors |
| US9376418B2 (en) | 2012-06-22 | 2016-06-28 | Merck Sharp & Dohme Corp. | Substituted pyridine spleen tyrosine kinase (SYK) inhibitors |
| WO2013192088A1 (en) | 2012-06-22 | 2013-12-27 | Merck Sharp & Dohme Corp. | SUBSTITUTED DIAZINE AND TRIAZINE SPLEEN TYROSINE KINASE (Syk) INHIBITORS |
| EP2884982B1 (en) | 2012-08-20 | 2017-09-20 | Merck Sharp & Dohme Corp. | SUBSTITUTED PHENYL SPLEEN TYROSINE KINASE (Syk) INHIBITORS |
| WO2014048065A1 (en) | 2012-09-28 | 2014-04-03 | Merck Sharp & Dohme Corp. | Triazolyl derivatives as syk inhibitors |
| EP2931281B1 (en) | 2012-12-12 | 2018-01-17 | Merck Sharp & Dohme Corp. | Amino-pyrimidine-containing spleen tyrosine kinase inhibitors |
| EP2934525B1 (en) | 2012-12-21 | 2019-05-08 | Merck Sharp & Dohme Corp. | Thiazole-substituted aminopyridines as spleen tyrosine kinase inhibitors |
| CN105188759A (zh) * | 2013-03-14 | 2015-12-23 | 阿勒根公司 | 持续释放递送的组合物以及在制造过程中稳定蛋白质的方法 |
| EP2988744A4 (en) | 2013-04-26 | 2016-11-02 | Merck Sharp & Dohme | THIAZOLSUBSTITUTED AMINOHETEROARYLE AS MILZTYROSINKINASE INHIBITOR |
| WO2014176216A1 (en) | 2013-04-26 | 2014-10-30 | Merck Sharp & Dohme Corp. | Thiazole-substituted aminopyrimidines as spleen tyrosine kinase inhibitors |
| US9670196B2 (en) | 2013-12-20 | 2017-06-06 | Merck Sharp & Dohme Corp. | Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors |
| WO2015094997A1 (en) | 2013-12-20 | 2015-06-25 | Merck Sharp & Dohme Corp. | Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors |
| EP3083559B1 (en) | 2013-12-20 | 2021-03-10 | Merck Sharp & Dohme Corp. | Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors |
| WO2015138273A1 (en) | 2014-03-13 | 2015-09-17 | Merck Sharp & Dohme Corp. | 2-pyrazine carboxamides as spleen tyrosine kinase inhibitors |
| WO2018189566A1 (en) * | 2017-04-10 | 2018-10-18 | Dorian Bevec | Use of a chemical compound as a therapeutic agent |
| US11149029B2 (en) * | 2018-07-18 | 2021-10-19 | Astrazeneca Ab | Salts of IJAK inhibitors and methods of using the same |
| CA3129665A1 (en) | 2019-03-21 | 2020-09-24 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| KR20220098759A (ko) | 2019-11-08 | 2022-07-12 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | 키나제 억제제에 대해 내성을 획득한 암의 치료 방법 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| GB9808802D0 (en) * | 1998-04-24 | 1998-06-24 | Glaxo Group Ltd | Pharmaceutical formulations |
| TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| GB0208609D0 (en) * | 2002-04-13 | 2002-05-22 | Glaxo Group Ltd | Compositions |
| US20040138200A1 (en) * | 2002-10-04 | 2004-07-15 | Michael Hawley | Pharmaceutical compositions for treatment of Parkinson's disease |
| ES2421139T3 (es) * | 2003-07-30 | 2013-08-29 | Rigel Pharmaceuticals, Inc. | Compuestos de 2,4-pirimidindiamina para su uso en el tratamiento o la prevención de enfermedades autoinmunitarias |
| KR20080024532A (ko) * | 2005-06-15 | 2008-03-18 | 베링거 인겔하임 인터내셔날 게엠베하 | 신규한 티오트로퓸 염의 제조방법, 신규한 티오트로퓸 염및 이의 약제학적 조성물 |
| US8198450B2 (en) * | 2006-06-30 | 2012-06-12 | Novartis Ag | Quinolinone derivatives and their pharmaceutical compositions |
-
2008
- 2008-08-27 ES ES08806983.6T patent/ES2452965T3/es active Active
- 2008-08-27 WO PCT/IB2008/002288 patent/WO2009031011A2/en not_active Ceased
- 2008-08-27 US US12/676,075 patent/US8193181B2/en not_active Expired - Fee Related
- 2008-08-27 NZ NZ583582A patent/NZ583582A/en not_active IP Right Cessation
- 2008-08-27 AU AU2008294473A patent/AU2008294473B2/en not_active Ceased
- 2008-08-27 RU RU2010108162/04A patent/RU2458925C2/ru active
- 2008-08-27 CN CN200880105757XA patent/CN101861314B/zh not_active Expired - Fee Related
- 2008-08-27 CA CA2697495A patent/CA2697495C/en not_active Expired - Fee Related
- 2008-08-27 KR KR1020107007283A patent/KR101225233B1/ko not_active Expired - Fee Related
- 2008-08-27 KR KR1020127024371A patent/KR20120120453A/ko not_active Withdrawn
- 2008-08-27 EP EP08806983.6A patent/EP2215087B1/en not_active Not-in-force
- 2008-08-27 BR BRPI0816278A patent/BRPI0816278A2/pt not_active Application Discontinuation
- 2008-08-27 MX MX2010002518A patent/MX2010002518A/es active IP Right Grant
- 2008-09-03 JP JP2008225403A patent/JP2009084270A/ja active Pending
- 2008-09-04 AR ARP080103848A patent/AR068369A1/es unknown
- 2008-09-04 TW TW097133970A patent/TWI371277B/zh not_active IP Right Cessation
-
2010
- 2010-02-15 IL IL203973A patent/IL203973A/en active IP Right Grant
- 2010-04-01 ZA ZA2010/02356A patent/ZA201002356B/en unknown
-
2012
- 2012-05-09 US US13/467,850 patent/US8486935B2/en not_active Expired - Fee Related
-
2013
- 2013-06-18 US US13/920,434 patent/US20130281446A1/en not_active Abandoned
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