JP2004516013A5 - - Google Patents

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Publication number
JP2004516013A5
JP2004516013A5 JP2002514188A JP2002514188A JP2004516013A5 JP 2004516013 A5 JP2004516013 A5 JP 2004516013A5 JP 2002514188 A JP2002514188 A JP 2002514188A JP 2002514188 A JP2002514188 A JP 2002514188A JP 2004516013 A5 JP2004516013 A5 JP 2004516013A5
Authority
JP
Japan
Prior art keywords
polypeptide
seq
nucleic acid
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2002514188A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004516013A (ja
Filing date
Publication date
Priority claimed from PCT/US2000/020710 external-priority patent/WO2001009327A2/en
Priority claimed from US09/643,657 external-priority patent/US6642024B1/en
Priority claimed from PCT/US2000/023522 external-priority patent/WO2001016319A2/en
Priority claimed from PCT/US2000/023328 external-priority patent/WO2001016318A2/en
Priority claimed from PCT/US2000/030952 external-priority patent/WO2001049715A2/en
Priority claimed from PCT/US2000/030873 external-priority patent/WO2001040465A2/en
Priority claimed from PCT/US2000/032678 external-priority patent/WO2001040466A2/en
Priority claimed from PCT/US2000/034956 external-priority patent/WO2001046420A2/en
Priority claimed from US09/747,259 external-priority patent/US6569645B2/en
Priority claimed from US09/767,609 external-priority patent/US20020042367A1/en
Priority claimed from PCT/US2001/006520 external-priority patent/WO2001068848A2/en
Priority claimed from PCT/US2001/006666 external-priority patent/WO2001066740A2/en
Priority claimed from US09/816,744 external-priority patent/US6579520B2/en
Priority claimed from US09/828,366 external-priority patent/US20020010137A1/en
Priority claimed from US09/854,208 external-priority patent/US7217412B2/en
Priority claimed from PCT/US2001/017092 external-priority patent/WO2001092331A2/en
Priority claimed from US09/866,034 external-priority patent/US20030170864A1/en
Priority claimed from US09/866,028 external-priority patent/US6642360B2/en
Priority claimed from PCT/US2001/017443 external-priority patent/WO2002016611A2/en
Priority claimed from US09/870,574 external-priority patent/US6551799B2/en
Priority claimed from PCT/US2001/017800 external-priority patent/WO2001093983A1/en
Priority claimed from PCT/US2001/019692 external-priority patent/WO2002000690A2/en
Application filed filed Critical
Priority claimed from PCT/US2001/021735 external-priority patent/WO2002008284A2/en
Publication of JP2004516013A publication Critical patent/JP2004516013A/ja
Publication of JP2004516013A5 publication Critical patent/JP2004516013A5/ja
Withdrawn legal-status Critical Current

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JP2002514188A 2000-07-20 2001-07-09 血管形成に関連する障害を診断及び治療するための組成物と方法 Withdrawn JP2004516013A (ja)

Applications Claiming Priority (36)

Application Number Priority Date Filing Date Title
US21955600P 2000-07-20 2000-07-20
US22066400P 2000-07-25 2000-07-25
US22062400P 2000-07-25 2000-07-25
PCT/US2000/020710 WO2001009327A2 (en) 1999-07-28 2000-07-28 Method of preventing the injury or death of retinal cells and treating ocular diseases
US22269500P 2000-08-02 2000-08-02
US09/643,657 US6642024B1 (en) 1998-01-29 2000-08-17 Guanylate-binding protein
PCT/US2000/023522 WO2001016319A2 (en) 1999-08-31 2000-08-23 Compositions and methods for the treatment of immune related diseases
PCT/US2000/023328 WO2001016318A2 (en) 1999-09-01 2000-08-24 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US23097800P 2000-09-07 2000-09-07
US66461000A 2000-09-18 2000-09-18
US66535000A 2000-09-18 2000-09-18
US24292200P 2000-10-24 2000-10-24
US70923800A 2000-11-08 2000-11-08
PCT/US2000/030952 WO2001049715A2 (en) 2000-01-06 2000-11-08 Methods and compositions for inhibiting neoplastic cell growth
PCT/US2000/030873 WO2001040465A2 (en) 1999-11-30 2000-11-10 Compositions and methods for the treatment of immune related diseases
PCT/US2000/032678 WO2001040466A2 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/747,259 US6569645B2 (en) 1999-05-14 2000-12-20 IL-17 homologous polypeptides and therapeutic uses thereof
PCT/US2000/034956 WO2001046420A2 (en) 1999-12-23 2000-12-20 Il-17 and il-17r homologous polypeptides and therapeutic uses thereof
US09/767,609 US20020042367A1 (en) 1997-11-25 2001-01-22 Fibroblast growth factor-19 (FGF-19) nucleic acids and polypeptides and methods of use for the treatment of obesity and related disorders
US79649801A 2001-02-28 2001-02-28
PCT/US2001/006520 WO2001068848A2 (en) 2000-03-01 2001-02-28 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/006666 WO2001066740A2 (en) 2000-03-03 2001-03-01 Compositions and methods for the treatment of immune related diseases
US80270601A 2001-03-09 2001-03-09
US80868901A 2001-03-14 2001-03-14
US09/816,744 US6579520B2 (en) 1998-05-15 2001-03-22 IL-17 related mammalian cytokine polypeptides (IL-17E)
US09/828,366 US20020010137A1 (en) 1997-09-18 2001-04-05 Methods and compositions for inhibiting neoplastic cell growth
US09/854,208 US7217412B2 (en) 1998-05-15 2001-05-10 IL-17C related mammalian cytokine polypeptides
US09/854,280 US7115398B2 (en) 1998-05-15 2001-05-10 IL-17 homologous polypeptides and therapeutic uses thereof
PCT/US2001/017092 WO2001092331A2 (en) 2000-05-30 2001-05-25 Compositions and methods for the treatment of immune related diseases
US09/866,034 US20030170864A1 (en) 2000-05-30 2001-05-25 Secreted and transmembrane polypeptides and nucleic acids encoding the same
US09/866,028 US6642360B2 (en) 1997-12-03 2001-05-25 Secreted polypeptides that stimulate release of proteoglycans from cartilage
PCT/US2001/017443 WO2002016611A2 (en) 2000-08-24 2001-05-30 Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US09/870,574 US6551799B2 (en) 1999-12-07 2001-05-30 Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
PCT/US2001/017800 WO2001093983A1 (en) 2000-06-02 2001-06-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/019692 WO2002000690A2 (en) 2000-06-23 2001-06-20 Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
PCT/US2001/021735 WO2002008284A2 (en) 2000-07-20 2001-07-09 Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis

Related Child Applications (4)

Application Number Title Priority Date Filing Date
JP2008194678A Division JP2009039117A (ja) 2000-07-20 2008-07-29 血管形成に関連する障害を診断及び治療するための組成物と方法
JP2008194764A Division JP2009039119A (ja) 2000-07-20 2008-07-29 血管形成に関連する障害を診断及び治療するための組成物と方法
JP2008194721A Division JP2009039118A (ja) 2000-07-20 2008-07-29 血管形成に関連する障害を診断及び治療するための組成物と方法
JP2011173336A Division JP6033531B2 (ja) 2000-07-20 2011-08-08 血管形成に関連する障害を診断及び治療するための組成物と方法

Publications (2)

Publication Number Publication Date
JP2004516013A JP2004516013A (ja) 2004-06-03
JP2004516013A5 true JP2004516013A5 (OSRAM) 2010-07-15

Family

ID=56290165

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2002514188A Withdrawn JP2004516013A (ja) 2000-07-20 2001-07-09 血管形成に関連する障害を診断及び治療するための組成物と方法
JP2008194721A Withdrawn JP2009039118A (ja) 2000-07-20 2008-07-29 血管形成に関連する障害を診断及び治療するための組成物と方法
JP2008194678A Withdrawn JP2009039117A (ja) 2000-07-20 2008-07-29 血管形成に関連する障害を診断及び治療するための組成物と方法
JP2008194764A Withdrawn JP2009039119A (ja) 2000-07-20 2008-07-29 血管形成に関連する障害を診断及び治療するための組成物と方法
JP2011173336A Expired - Fee Related JP6033531B2 (ja) 2000-07-20 2011-08-08 血管形成に関連する障害を診断及び治療するための組成物と方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2008194721A Withdrawn JP2009039118A (ja) 2000-07-20 2008-07-29 血管形成に関連する障害を診断及び治療するための組成物と方法
JP2008194678A Withdrawn JP2009039117A (ja) 2000-07-20 2008-07-29 血管形成に関連する障害を診断及び治療するための組成物と方法
JP2008194764A Withdrawn JP2009039119A (ja) 2000-07-20 2008-07-29 血管形成に関連する障害を診断及び治療するための組成物と方法
JP2011173336A Expired - Fee Related JP6033531B2 (ja) 2000-07-20 2011-08-08 血管形成に関連する障害を診断及び治療するための組成物と方法

Country Status (5)

Country Link
EP (1) EP1309685A2 (OSRAM)
JP (5) JP2004516013A (OSRAM)
AU (1) AU2001271973A1 (OSRAM)
CA (1) CA2416538A1 (OSRAM)
WO (1) WO2002008284A2 (OSRAM)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999012963A2 (en) 1997-09-12 1999-03-18 Biogen, Inc. Cysteine rich receptors: trail
US7419663B2 (en) 1998-03-20 2008-09-02 Genentech, Inc. Treatment of complement-associated disorders
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
PT1076703E (pt) 1998-05-15 2007-10-10 Genentech Inc ''utilizações terapêuticas de polipéptido homólogos de il-17''
US7771719B1 (en) 2000-01-11 2010-08-10 Genentech, Inc. Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E
US20030190669A1 (en) 1998-12-30 2003-10-09 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20030095967A1 (en) 1999-01-25 2003-05-22 Mackay Fabienne BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders
US20030119113A1 (en) 1999-07-20 2003-06-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
ES2317846T3 (es) 1999-08-12 2009-05-01 Agensys, Inc. Antigeno transmembranal de lectina tipo c en el cancer de prostata humano y usos del mismo.
EP1892249A1 (en) * 1999-09-01 2008-02-27 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU775272B2 (en) 1999-10-28 2004-07-29 Agensys, Inc. 36P6D5: secreted tumor antigen
US20040043397A1 (en) 2000-01-11 2004-03-04 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
DK1897944T3 (da) * 1999-12-23 2011-10-24 Genentech Inc IL-17 homologe polypeptider og terapeutisk anvendelse deraf
US7718397B2 (en) 2000-03-21 2010-05-18 Genentech, Inc. Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof
EP1283214B1 (en) * 2000-04-21 2007-02-14 Fuso Pharmaceutical Industries Ltd. Novel collectins
US20030096969A1 (en) 2000-06-02 2003-05-22 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2004506413A (ja) * 2000-06-23 2004-03-04 ジェネンテック・インコーポレーテッド 血管形成に関与する疾患の診断と治療のための組成物と方法
CA2648051A1 (en) * 2000-06-23 2002-01-03 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
EP2275549A1 (en) * 2000-06-23 2011-01-19 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
US7265210B2 (en) 2000-09-15 2007-09-04 Genentech, Inc. Anti-PRO9821 antibodies
US6630325B1 (en) * 2000-10-19 2003-10-07 Maine Medical Center Research Institute Compositions, methods and kits relating to remodel
EP1332157A2 (en) 2000-11-03 2003-08-06 The Regents of the University of California Prokineticin polypeptides, related compositions and methods
JP2004535758A (ja) 2000-11-14 2004-12-02 ブリストル−マイヤーズ スクイブ カンパニー リンパ様細胞lsi−01から分泌される新規なヒトセルピンをコードするポリヌクレオチド
US7135334B2 (en) 2001-06-20 2006-11-14 Genentech, Inc. PRO20044 nucleic acids
WO2003080667A2 (en) * 2002-03-22 2003-10-02 Bioxell S.P.A. A novel receptor trem (triggering receptor expressed on myeloid cells) and uses thereof
JPWO2003083114A1 (ja) * 2002-03-28 2005-08-04 アステラス製薬株式会社 アンジオポエチン関連増殖因子
KR20040101502A (ko) * 2002-04-16 2004-12-02 제넨테크, 인크. 종양의 진단 및 치료 방법 및 이를 위한 조성물
EP2305710A3 (en) 2002-06-03 2013-05-29 Genentech, Inc. Synthetic antibody phage libraries
WO2004022087A1 (ja) * 2002-09-04 2004-03-18 Takeda Pharmaceutical Company Limited 疾患関連遺伝子の用途
CA2497661A1 (en) * 2002-09-11 2004-03-25 Genentech, Inc. Compositions and methods for the diagnosis of immune related diseases using pro71061
CA2499843A1 (en) * 2002-09-25 2004-04-08 Genentech, Inc. Novel compositions and methods for the treatment of psoriasis
CA2515288A1 (en) 2003-03-12 2004-09-23 Genentech, Inc. Compositions with hematopoietic and immune activity
MX341074B (es) 2003-07-08 2016-08-05 Genentech Inc Polipeptidos heterologos il-17 a/f y usos terapeuticos de los mismos.
US20100031378A1 (en) 2008-08-04 2010-02-04 Edwards Joel A Novel gene disruptions, compositions and methods relating thereto
JP5599136B2 (ja) 2004-04-14 2014-10-01 ジェネンテック, インコーポレイテッド 血管の発達を調節するための、egfl7アンタゴニストを含む組成物
DK1781682T3 (da) 2004-06-24 2013-06-03 Mayo Foundation B7-H5, et kostimulerende polypeptid
AU2005270078A1 (en) 2004-07-02 2006-02-09 Genentech, Inc. Compositions and methods for treatment of non-hodgkin's lymphoma
WO2006017673A2 (en) 2004-08-03 2006-02-16 Biogen Idec Ma Inc. Taj in neuronal function
US7906116B2 (en) 2005-09-01 2011-03-15 Parkash Gill Methods for using and identifying modulators of Delta-like 4
KR20180002911A (ko) 2005-11-04 2018-01-08 제넨테크, 인크. 안질환 치료를 위한 보체 경로 억제제의 용도
AU2007313685C1 (en) 2006-11-02 2015-09-17 Genentech, Inc. Humanized anti-Factor D antibodies
AR066660A1 (es) 2007-05-23 2009-09-02 Genentech Inc Prevencion y tratamiento de condiciones del ojo asociadas con su complemento
CA2705879A1 (en) 2007-11-21 2009-06-04 Amgen Inc. Wise binding agents and epitopes
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
NZ588674A (en) 2008-05-05 2013-02-22 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
EP2280996B1 (en) 2008-05-06 2016-09-07 Genentech, Inc. AFFINITY MATURED CRIg VARIANTS
DK2398902T3 (da) 2009-02-20 2023-12-04 Astellas Pharma Inc Fremgangsmåder og sammensætninger til diagnosticering og behandling af cancer
SG175276A1 (en) 2009-05-05 2011-11-28 Novimmune Sa Anti-il-17f antibodies and methods of use thereof
RU2011149798A (ru) 2009-05-08 2013-06-20 Дженентек, Инк. Гуманизированные анти-egfl7-антитела и способы их применения
AT508569A1 (de) 2009-07-23 2011-02-15 Affiris Ag Pharmaceutical compound
SG10202110692WA (en) 2009-11-11 2021-12-30 Ganymed Pharmaceuticals Gmbh Antibodies specific for claudin 6 (cldn6)
EP2404936A1 (en) 2010-07-06 2012-01-11 Ganymed Pharmaceuticals AG Cancer therapy using CLDN6 target-directed antibodies in vivo
MX341147B (es) 2011-05-13 2016-08-09 Ganymed Pharmaceuticals Ag Anticuerpos para el tratamiento del cáncer que expresa cldn6.
EP2726511B1 (en) 2011-07-01 2019-08-07 NGM Biopharmaceuticals, Inc. Compositions, uses and methods for treatment of metabolic disorders and diseases
EP2925775B1 (en) 2012-11-28 2020-09-16 NGM Biopharmaceuticals, Inc. Compositions and methods for treatment of metabolic disorders and diseases
US9290557B2 (en) 2012-11-28 2016-03-22 Ngm Biopharmaceuticals, Inc. Compositions comprising variants and fusions of FGF19 polypeptides
KR102724421B1 (ko) 2012-12-27 2024-10-30 엔지엠 바이오파마슈티컬스, 아이엔씨. 담즙산 항상성의 조절 및 담즙산 질환 및 질병의 치료 방법
US9273107B2 (en) 2012-12-27 2016-03-01 Ngm Biopharmaceuticals, Inc. Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
US10369198B2 (en) * 2013-01-17 2019-08-06 Medizinische Hochschule Hannover Factor 1 protein, factor 2 protein and inhibitors thereof for use in treating or preventing diseases
WO2015014376A1 (en) 2013-07-31 2015-02-05 Biontech Ag Diagnosis and therapy of cancer involving cancer stem cells
MX2016001854A (es) 2013-08-12 2016-09-06 Genentech Inc Composiciones y metodo para tratar condiciones asociadas con el complemento.
KR102178945B1 (ko) 2013-10-28 2020-11-13 엔지엠 바이오파마슈티컬스, 아이엔씨. 암 모델 및 관련 방법
SI3097122T1 (sl) 2014-01-24 2020-07-31 Ngm Biopharmaceuticals, Inc. Protitelesa, ki se vežejo v domeni beta klotho 2, in metode za njihovo uporabo
EA201692109A1 (ru) 2014-05-01 2017-03-31 Дженентек, Инк. Варианты антител к фактору d и их применение
WO2015183890A2 (en) 2014-05-28 2015-12-03 Ngm Biopharmaceuticals, Inc. Methods and compositions for the treatment of metabolic disorders and diseases
CA2951153A1 (en) 2014-06-16 2015-12-23 Ngm Biopharmaceuticals, Inc. Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
CN107108711B (zh) 2014-10-23 2021-11-23 恩格姆生物制药公司 包含肽变异体的药物组合物及其使用方法
US10434144B2 (en) 2014-11-07 2019-10-08 Ngm Biopharmaceuticals, Inc. Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders
US10800843B2 (en) 2015-07-29 2020-10-13 Ngm Biopharmaceuticals, Inc. Beta klotho-binding proteins
WO2017075173A2 (en) 2015-10-30 2017-05-04 Genentech, Inc. Anti-factor d antibodies and conjugates
JP2018536650A (ja) 2015-10-30 2018-12-13 ジェネンテック, インコーポレイテッド 抗d因子抗体変異体コンジュゲート及びその使用
JP6728352B2 (ja) 2015-11-09 2020-07-22 エヌジーエム バイオファーマシューティカルス,インコーポレーテッド 胆汁酸に関係した障害の治療方法
CA3034399A1 (en) 2016-08-26 2018-03-01 Ngm Biopharmaceuticals, Inc. Methods of treating fibroblast growth factor 19-mediated cancers and tumors
GB201906052D0 (en) * 2019-04-30 2019-06-12 Int Centre For Genetic Engineering And Biotechnology Proteins with cardioprotective activity

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000015792A2 (en) * 1998-09-14 2000-03-23 Genentech, Inc. Promotion or inhibition of angiogenesis and cardiovascularization
WO2000032221A2 (en) * 1998-12-01 2000-06-08 Genentech, Inc. Promotion or inhibition of angiogenesis and cardiovascularization
WO2000053751A1 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth
JP2002532054A (ja) * 1997-08-29 2002-10-02 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 29個のヒト分泌タンパク質
JP2002506615A (ja) * 1998-02-27 2002-03-05 財団法人相模中央化学研究所 膜貫通ドメインを有するヒト蛋白質とそれをコードするdna
JP3868740B2 (ja) * 1998-03-10 2007-01-17 ジェネンテック・インコーポレーテッド 新規なポリペプチド及びそれをコードする核酸
CA2324492A1 (en) * 1998-03-31 1999-10-07 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
JP2004513602A (ja) * 1999-03-08 2004-05-13 ジェネンテック・インコーポレーテッド 分泌及び膜貫通ポリペプチドとそれをコードしている核酸
KR100543857B1 (ko) * 1999-09-01 2006-01-23 제넨테크, 인크. 혈관신생 및 심혈관형성의 촉진 또는 억제
JP2004506413A (ja) * 2000-06-23 2004-03-04 ジェネンテック・インコーポレーテッド 血管形成に関与する疾患の診断と治療のための組成物と方法

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