JP2004504295A - 安定化１α−ヒドロキシビタミンＤ - Google Patents

安定化１α−ヒドロキシビタミンＤ Download PDF

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Publication number
JP2004504295A
JP2004504295A JP2002512124A JP2002512124A JP2004504295A JP 2004504295 A JP2004504295 A JP 2004504295A JP 2002512124 A JP2002512124 A JP 2002512124A JP 2002512124 A JP2002512124 A JP 2002512124A JP 2004504295 A JP2004504295 A JP 2004504295A
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shvd
hydroxyvitamin
stabilized
composition
vitamin
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JP2004504295A5 (https=
Inventor
ナットソン　ジョイス　シー
マゼス　リチャード　ビー
ビショップ　チャールズ　ダブリュー
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ボーン　ケア　インターナショナル　インコーポレイテッド
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Application filed by ボーン　ケア　インターナショナル　インコーポレイテッド filed Critical ボーン　ケア　インターナショナル　インコーポレイテッド
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Publication of JP2004504295A5 publication Critical patent/JP2004504295A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2002512124A 2000-07-18 2001-07-18 安定化１α−ヒドロキシビタミンＤ Pending JP2004504295A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21906800P 2000-07-18 2000-07-18
PCT/US2001/022729 WO2002006218A2 (en) 2000-07-18 2001-07-18 STABILIZED 1α-HYDROXY VITAMIN D

Publications (2)

Publication Number Publication Date
JP2004504295A true JP2004504295A (ja) 2004-02-12
JP2004504295A5 JP2004504295A5 (https=) 2008-09-04

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ID=22817719

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002512124A Pending JP2004504295A (ja) 2000-07-18 2001-07-18 安定化１α−ヒドロキシビタミンＤ

Country Status (7)

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US (2) US6903083B2 (https=)
EP (2) EP1301479A2 (https=)
JP (1) JP2004504295A (https=)
AU (2) AU7895601A (https=)
CA (1) CA2414407A1 (https=)
IL (2) IL153378A0 (https=)
WO (1) WO2002006218A2 (https=)

Cited By (3)

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JP2005247803A (ja) * 2004-03-08 2005-09-15 Zeria Pharmaceut Co Ltd 点眼剤及びその容器
JP2014062131A (ja) * 2008-03-12 2014-04-10 Cytochroma Inc 安定化１，２５−ジヒドロキシビタミンｄ２及びその製造方法
JP2018172299A (ja) * 2017-03-31 2018-11-08 ナガセ医薬品株式会社 マキサカルシトール含有水溶液製剤

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JP2005515996A (ja) * 2001-12-03 2005-06-02 ノバセア インコーポレイティッド 活性型ビタミンｄ化合物を含む薬学的組成物
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20050101576A1 (en) * 2003-11-06 2005-05-12 Novacea, Inc. Methods of using vitamin D compounds in the treatment of myelodysplastic syndromes
US7351869B2 (en) * 2002-11-18 2008-04-01 Teva Pharmaceutical Industries Ltd Crystallization method for purification of calcipotriene
US20050026877A1 (en) * 2002-12-03 2005-02-03 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
US20050020546A1 (en) * 2003-06-11 2005-01-27 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
JP5161582B2 (ja) * 2004-11-22 2013-03-13 ウィスコンシン・アルムニ・リサーチ・ファウンデーション １７，２０（ｚ）−デヒドロビタミンｄ類似体およびそれらの使用
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JP5645408B2 (ja) * 2006-11-16 2014-12-24 カイ ファーマシューティカルズ インコーポレーティッド 副甲状腺機能亢進症および高カルシウム血症性障害の治療のためのポリカチオン性カルシウムモジュレーターペプチド
HUE073014T2 (hu) * 2007-04-25 2025-12-28 Opko Renal Llc Eljárás a másodlagos hyperparathyreoidismus biztonságos és hatékony kezelésére és megelõzésére krónikus vesebetegség esetén
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US8592401B2 (en) * 2007-04-25 2013-11-26 Proventiv Therapeutics, Llc Methods and compounds for vitamin D therapy
KR20190028822A (ko) 2007-04-25 2019-03-19 사이토크로마 인코포레이티드 비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
CA2710954C (en) * 2007-12-28 2015-07-21 Wisconsin Alumni Research Foundation (20s)-23,23-difluoro-2-methylene-19-nor-bishomopregnacalciferol-vitamin d analogs
US7718638B2 (en) * 2007-12-28 2010-05-18 Wisconsin Alumni Research Foundation (20R)-23,23-difluoro-2-methylene-19-nor-bishomopregnacalciferol-vitamin D analogs
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US8013176B2 (en) * 2008-09-11 2011-09-06 Alphora Research Inc. Paricalcitol purification
CN102264751A (zh) * 2008-11-26 2011-11-30 赛特克罗公司 合成维生素d类似物的方法
US8999932B2 (en) 2009-07-29 2015-04-07 Kai Pharmaceuticals, Inc. Therapeutic agents for reducing parathyroid hormone levels
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CA2698160C (en) * 2010-03-30 2017-07-25 Alphora Research Inc. Stabilized doxercalciferol and process for manufacturing the same
US20120108554A1 (en) * 2010-10-28 2012-05-03 Formosa Laboratories, Inc. PROCESS FOR PREPARING HIGH PURITY 1alpha-HYDROXY VITAMIN D2
HRP20161566T1 (hr) 2011-06-08 2017-02-24 Kai Pharmaceuticals, Inc. Terapijski agensi za reguliranje serumskog fosfora
CN109985228A (zh) 2011-11-10 2019-07-09 凯伊药品公司 拟钙剂及其使用方法
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
CN105348164B (zh) * 2015-10-29 2017-03-29 无锡福祈制药有限公司 一种1α‑羟基维生素D2的制备方法
JP7032322B2 (ja) 2016-03-28 2022-03-08 オプコ アイルランド グローバル ホールディングス リミテッド ビタミンｄ治療法
CN106748642B (zh) * 2016-11-28 2019-11-05 无锡福祈制药有限公司 一种度骨化醇类似物wxfq-65的合成方法
CN106748942B (zh) * 2016-11-28 2018-06-29 无锡福祈制药有限公司 度骨化醇类似物wxfq-65及其合成方法
CN113666858A (zh) * 2021-08-20 2021-11-19 江苏四环生物制药有限公司 一种度骨化醇及其制备方法

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