JP2004504295A - 安定化１α−ヒドロキシビタミンＤ - Google Patents

安定化１α−ヒドロキシビタミンＤ Download PDF

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Publication number
JP2004504295A
JP2004504295A JP2002512124A JP2002512124A JP2004504295A JP 2004504295 A JP2004504295 A JP 2004504295A JP 2002512124 A JP2002512124 A JP 2002512124A JP 2002512124 A JP2002512124 A JP 2002512124A JP 2004504295 A JP2004504295 A JP 2004504295A
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shvd
hydroxyvitamin
stabilized
composition
vitamin
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JP2004504295A5 (enExample
Inventor
ナットソン　ジョイス　シー
マゼス　リチャード　ビー
ビショップ　チャールズ　ダブリュー
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ボーン　ケア　インターナショナル　インコーポレイテッド
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Application filed by ボーン　ケア　インターナショナル　インコーポレイテッド filed Critical ボーン　ケア　インターナショナル　インコーポレイテッド
Publication of JP2004504295A publication Critical patent/JP2004504295A/ja
Publication of JP2004504295A5 publication Critical patent/JP2004504295A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2002512124A 2000-07-18 2001-07-18 安定化１α−ヒドロキシビタミンＤ Pending JP2004504295A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21906800P 2000-07-18 2000-07-18
PCT/US2001/022729 WO2002006218A2 (en) 2000-07-18 2001-07-18 STABILIZED 1α-HYDROXY VITAMIN D

Publications (2)

Publication Number Publication Date
JP2004504295A true JP2004504295A (ja) 2004-02-12
JP2004504295A5 JP2004504295A5 (enExample) 2008-09-04

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ID=22817719

Family Applications (1)

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JP2002512124A Pending JP2004504295A (ja) 2000-07-18 2001-07-18 安定化１α−ヒドロキシビタミンＤ

Country Status (7)

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US (2) US6903083B2 (enExample)
EP (2) EP1301479A2 (enExample)
JP (1) JP2004504295A (enExample)
AU (2) AU7895601A (enExample)
CA (1) CA2414407A1 (enExample)
IL (2) IL153378A0 (enExample)
WO (1) WO2002006218A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005247803A (ja) * 2004-03-08 2005-09-15 Zeria Pharmaceut Co Ltd 点眼剤及びその容器
JP2014062131A (ja) * 2008-03-12 2014-04-10 Cytochroma Inc 安定化１，２５−ジヒドロキシビタミンｄ２及びその製造方法
JP2018172299A (ja) * 2017-03-31 2018-11-08 ナガセ医薬品株式会社 マキサカルシトール含有水溶液製剤

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US20030191093A1 (en) * 2001-12-03 2003-10-09 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20050101576A1 (en) * 2003-11-06 2005-05-12 Novacea, Inc. Methods of using vitamin D compounds in the treatment of myelodysplastic syndromes
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US20050020546A1 (en) * 2003-06-11 2005-01-27 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
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CA2669914C (en) * 2006-11-16 2017-11-07 Kai Pharmaceuticals, Inc. Polycationic calcium modulator peptides for the treatment of hyperparathyroidism and hypercalcemic disorders
PT2148661E (pt) 2007-04-25 2013-03-06 Proventiv Therapeutics Llc Composições orais de libertação controlada compreendendo um composto de vitamina d e veículo ceroso
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ES3047207T3 (en) * 2007-04-25 2025-12-03 Opko Renal Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
PT2148684E (pt) * 2007-04-25 2013-04-19 Cytochroma Inc Método de tratamento para a insuficiência e deficiência de vitamina d
EP2237837B1 (en) * 2007-12-28 2012-08-22 Wisconsin Alumni Research Foundation (20r)-23,23-difluoro-2-methylene-19-nor-bishomopregnacalciferol-vitamin d analogs
CA2710954C (en) * 2007-12-28 2015-07-21 Wisconsin Alumni Research Foundation (20s)-23,23-difluoro-2-methylene-19-nor-bishomopregnacalciferol-vitamin d analogs
CN106853250A (zh) 2008-04-02 2017-06-16 赛特克罗公司 用于维生素d缺乏症和相关障碍的方法、组合物、用途和试剂盒
US8013176B2 (en) * 2008-09-11 2011-09-06 Alphora Research Inc. Paricalcitol purification
EP2376508A4 (en) * 2008-11-26 2012-06-13 Cytochroma Inc PROCESS FOR SYNTHESIS OF VITAMIN D ANALOGUE
JP5270799B2 (ja) 2009-07-29 2013-08-21 カイ・ファーマシューティカルズ・インコーポレイテッド 副甲状腺ホルモンを低減する治療剤
US11672809B2 (en) 2010-03-29 2023-06-13 Eirgen Pharma Ltd. Methods and compositions for reducing parathyroid levels
CA2698160C (en) * 2010-03-30 2017-07-25 Alphora Research Inc. Stabilized doxercalciferol and process for manufacturing the same
US20120108554A1 (en) * 2010-10-28 2012-05-03 Formosa Laboratories, Inc. PROCESS FOR PREPARING HIGH PURITY 1alpha-HYDROXY VITAMIN D2
CA2837445C (en) 2011-06-08 2022-10-04 Kai Pharmaceuticals, Inc. Therapeutic agents for regulating serum phosphorus
CN109985228A (zh) 2011-11-10 2019-07-09 凯伊药品公司 拟钙剂及其使用方法
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
CN105348164B (zh) * 2015-10-29 2017-03-29 无锡福祈制药有限公司 一种1α‑羟基维生素D2的制备方法
WO2017182237A1 (en) 2016-03-28 2017-10-26 Opko Ireland Global Holdings, Limited Methods of vitamin d treatment
CN106748642B (zh) * 2016-11-28 2019-11-05 无锡福祈制药有限公司 一种度骨化醇类似物wxfq-65的合成方法
CN106748942B (zh) * 2016-11-28 2018-06-29 无锡福祈制药有限公司 度骨化醇类似物wxfq-65及其合成方法
CN113666858A (zh) * 2021-08-20 2021-11-19 江苏四环生物制药有限公司 一种度骨化醇及其制备方法

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