JP2004504260A5 - - Google Patents
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- Publication number
- JP2004504260A5 JP2004504260A5 JP2000617916A JP2000617916A JP2004504260A5 JP 2004504260 A5 JP2004504260 A5 JP 2004504260A5 JP 2000617916 A JP2000617916 A JP 2000617916A JP 2000617916 A JP2000617916 A JP 2000617916A JP 2004504260 A5 JP2004504260 A5 JP 2004504260A5
- Authority
- JP
- Japan
- Prior art keywords
- antigenic composition
- composition according
- monophosphoryl lipid
- lymphokine
- cytokine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13396399P | 1999-05-13 | 1999-05-13 | |
| US60/133,963 | 1999-05-13 | ||
| PCT/US2000/013156 WO2000069456A2 (en) | 1999-05-13 | 2000-05-12 | Adjuvant combination formulations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011171095A Division JP5230780B2 (ja) | 1999-05-13 | 2011-08-04 | アジュバント混合製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004504260A JP2004504260A (ja) | 2004-02-12 |
| JP2004504260A5 true JP2004504260A5 (enExample) | 2007-07-05 |
| JP4974414B2 JP4974414B2 (ja) | 2012-07-11 |
Family
ID=22461127
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000617916A Expired - Fee Related JP4974414B2 (ja) | 1999-05-13 | 2000-05-12 | アジュバント混合製剤 |
| JP2011171095A Expired - Fee Related JP5230780B2 (ja) | 1999-05-13 | 2011-08-04 | アジュバント混合製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011171095A Expired - Fee Related JP5230780B2 (ja) | 1999-05-13 | 2011-08-04 | アジュバント混合製剤 |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US7611721B1 (enExample) |
| EP (1) | EP1178825B1 (enExample) |
| JP (2) | JP4974414B2 (enExample) |
| KR (1) | KR100863367B1 (enExample) |
| CN (1) | CN1192799C (enExample) |
| AT (1) | ATE516046T1 (enExample) |
| AU (1) | AU781469B2 (enExample) |
| BG (1) | BG106094A (enExample) |
| BR (1) | BR0010539A (enExample) |
| CA (2) | CA2372181C (enExample) |
| CZ (1) | CZ20013916A3 (enExample) |
| EA (1) | EA006233B1 (enExample) |
| EE (1) | EE200100597A (enExample) |
| ES (1) | ES2367625T3 (enExample) |
| GE (1) | GEP20053446B (enExample) |
| HR (1) | HRP20010839A2 (enExample) |
| HU (1) | HUP0201220A3 (enExample) |
| ID (1) | ID30407A (enExample) |
| IL (2) | IL146382A0 (enExample) |
| IS (1) | IS6156A (enExample) |
| MX (1) | MXPA01011499A (enExample) |
| NO (1) | NO20015523L (enExample) |
| NZ (1) | NZ515322A (enExample) |
| PL (1) | PL352312A1 (enExample) |
| SK (1) | SK16022001A3 (enExample) |
| TR (1) | TR200103266T2 (enExample) |
| UA (1) | UA76406C2 (enExample) |
| WO (1) | WO2000069456A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9326174D0 (en) * | 1993-12-22 | 1994-02-23 | Biocine Sclavo | Mucosal adjuvant |
| ID30407A (id) | 1999-05-13 | 2001-11-29 | American Cyanamid Co | Formulasi-formulasi kombinasi bahan penambah |
| DE60117164T2 (de) * | 2000-11-07 | 2006-08-03 | Immuno Vaccine Technologies Inc., Halifax | Impfstoffe mit erhöhter immunantwort und verfahren zur deren herstellung |
| WO2002038177A2 (en) | 2000-11-10 | 2002-05-16 | Wyeth Holdings Corporation | Adjuvant combination formulations |
| ES2588705T3 (es) | 2007-09-27 | 2016-11-04 | Immunovaccine Technologies Inc. | Uso de liposomas en un vehículo que comprende una fase hidrófoba continua para la entrega de polinucleótidos in vivo |
| JP2010539993A (ja) * | 2007-10-08 | 2010-12-24 | イントレキソン コーポレーション | 遺伝子操作した樹状細胞および癌の治療のための使用 |
| CA2723918C (en) | 2008-06-05 | 2018-01-09 | Immunovaccine Technologies Inc. | Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance |
| WO2011119920A2 (en) | 2010-03-25 | 2011-09-29 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| ES2667425T3 (es) | 2011-06-10 | 2018-05-10 | Oregon Health & Science University | Glucoproteínas y vectores recombinantes de CMV |
| GB201113570D0 (en) * | 2011-08-05 | 2011-09-21 | Glaxosmithkline Biolog Sa | Vaccine |
| IN2014CN02581A (enExample) | 2011-10-06 | 2015-08-07 | Immunovaccine Technologies Inc | |
| RU2496149C1 (ru) * | 2012-06-19 | 2013-10-20 | Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" (ФБУН ГНЦ ВБ "Вектор") | Способ оценки противооспенной активности лечебно-профилактических препаратов |
| JP6980534B2 (ja) | 2015-06-25 | 2021-12-15 | ザ チルドレンズ メディカル センター コーポレーション | 造血幹細胞の増大、富化、および維持に関する方法および組成物 |
| WO2017161001A1 (en) | 2016-03-15 | 2017-09-21 | Children's Medical Center Corporation | Methods and compositions relating to hematopoietic stem cell expansion |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666829A (en) | 1985-05-15 | 1987-05-19 | University Of California | Polypeptide marker for Alzheimer's disease and its use for diagnosis |
| US5391485A (en) | 1985-08-06 | 1995-02-21 | Immunex Corporation | DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues |
| US5078996A (en) | 1985-08-16 | 1992-01-07 | Immunex Corporation | Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor |
| US5939074A (en) | 1986-12-30 | 1999-08-17 | The United States Of America As Represented By The Department Of Health And Human Services | Multideterminant peptide antigens |
| US6294322B1 (en) | 1988-01-26 | 2001-09-25 | The United States Of America As Represented By The Department Of Health And Human Services | Multideterminant peptides that elicit helper T-lymphocyte cytotoxic T-lymphocyte and neutralizing antibody responses against HIV-1 |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US5013548A (en) | 1987-09-08 | 1991-05-07 | Duke University | Production of antibodies to HIV |
| US5993819A (en) | 1987-09-08 | 1999-11-30 | Duke University | Synthetic vaccine for protection against human immunodeficiency virus infection |
| US5019387A (en) | 1987-09-08 | 1991-05-28 | Duke University | Production of antibodies to HIV |
| US5223254A (en) | 1987-09-29 | 1993-06-29 | Praxis Biologics, Inc. | Respiratory syncytial virus: vaccines |
| CA1340506C (en) * | 1987-11-24 | 1999-04-20 | Nicholas H. Carbonetti | Production of gonorrheal pi proteins and vaccines |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| WO1990005147A1 (en) | 1988-11-10 | 1990-05-17 | Genetics Institute, Inc. | Natural killer stimulatory factor |
| US5073627A (en) | 1989-08-22 | 1991-12-17 | Immunex Corporation | Fusion proteins comprising GM-CSF and IL-3 |
| DE3934366A1 (de) | 1989-10-14 | 1991-04-18 | Chemotherapeutisches Forschungsinstitut Georg Speyer Haus | Vakzine zum schutz vor hiv-virusinfektionen, verfahren zu ihrer herstellung und ihre verwendung als diagnostikum und immuntherapeutikum |
| JP2980677B2 (ja) | 1990-04-27 | 1999-11-22 | マクマイケル,ジョン | 不正常なアミロイドβタンパク質と関連する中枢神経系疾患状態の治療のための方法および組成物 |
| SE502569C2 (sv) * | 1991-05-31 | 1995-11-13 | British Tech Group | Användning av en immunologiskt inert matris av en sterol och saponiner som kan bilda sfäriska nanopartiklar med snäv storleksfördelning som läkemedelsbärare, partiklar, komposition samt kit |
| EP0671947B1 (en) | 1991-12-02 | 2000-03-08 | The Board Of Regents, The University Of Texas System | Compositions for eliciting cytotoxic t-lymphocyte responses against viruses |
| US6037135A (en) | 1992-08-07 | 2000-03-14 | Epimmune Inc. | Methods for making HLA binding peptides and their uses |
| MX9304089A (es) | 1992-07-08 | 1994-01-31 | Schering Corp | Uso de gm-csf como una vacuna adyuvante. |
| US5593972A (en) | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
| KR100310510B1 (ko) * | 1993-03-23 | 2002-07-04 | 장 스테판느 | 3-0-탈아세틸화모노포스포릴지질a를함유하는백신조성물 |
| US5637480A (en) | 1993-05-12 | 1997-06-10 | Genetics Institute, Inc. | DNA molecules encoding bone morphogenetic protein-10 |
| RU2160119C2 (ru) | 1993-05-25 | 2000-12-10 | Американ Цианамид Компани | Вакцинная композиция, содержащая белок респираторно-синцитиального вируса (варианты) |
| US5830877A (en) | 1993-08-26 | 1998-11-03 | The Regents Of The University Of California | Method, compositions and devices for administration of naked polynucleotides which encode antigens and immunostimulatory |
| GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US5571515A (en) | 1994-04-18 | 1996-11-05 | The Wistar Institute Of Anatomy & Biology | Compositions and methods for use of IL-12 as an adjuvant |
| DE69527708T2 (de) * | 1994-04-29 | 2003-04-30 | Duke University, Durham | Synthetischer impfstoff zum schutz gegen infektionen mit dem menschlichen immunschwächevirus |
| AUPM543894A0 (en) | 1994-05-04 | 1994-05-26 | Commonwealth Scientific And Industrial Research Organisation | An adjuvant |
| AU3735095A (en) | 1994-09-30 | 1996-04-26 | Ludwig Institute For Cancer Research | Compositions containing a p53 derived protein or peptide, an adjuvant, and interleukin-12 and uses thereof |
| PT784486E (pt) | 1994-10-05 | 2006-07-31 | Univ Vanderbilt | Inerleucina-12 como um adjuvante para vacinas contra paramyxoviridae |
| AU4727296A (en) * | 1995-02-24 | 1996-09-11 | Cantab Pharmaceuticals Research Limited | Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation |
| US6613337B1 (en) | 1997-02-12 | 2003-09-02 | Corixa Corporation | Leishmania antigens for use in the therapy and diagnosis of leishmaniasis |
| EP0877816A1 (en) | 1996-02-01 | 1998-11-18 | North American Vaccine, Inc. | Expression of group b neisseria meningitidis outer membrane (mb3) protein from yeast and vaccines |
| US6096313A (en) | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
| US5762943A (en) * | 1996-05-14 | 1998-06-09 | Ribi Immunochem Research, Inc. | Methods of treating type I hypersensitivity using monophosphoryl lipid A |
| AU724743B2 (en) | 1996-05-31 | 2000-09-28 | Genetics Institute, Llc | IL-12 as an adjuvant for Bordetella Pertussis vaccines |
| US6024965A (en) | 1996-10-18 | 2000-02-15 | Erasums University Rotterdam | Induction of REV and TAT specific cytotoxic T-cells for prevention and treatment of human immunodeficiency virus (HIV) infection |
| CA2745736C (en) * | 1996-10-23 | 2016-11-22 | The Trustees Of The University Of Pennsylvania | Immunotherapy and improved vaccines |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| US6797276B1 (en) * | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
| US6350456B1 (en) * | 1997-03-13 | 2002-02-26 | Corixa Corporation | Compositions and methods for the prevention and treatment of M. tuberculosis infection |
| US6113918A (en) | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| GB9711990D0 (en) * | 1997-06-11 | 1997-08-06 | Smithkline Beecham Biolog | Vaccine |
| EP0988053A1 (en) | 1997-06-11 | 2000-03-29 | Aquila Biopharmaceuticals, Inc. | Purified saponins as oral adjuvants |
| GB9712347D0 (en) * | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| CA2295740A1 (en) | 1997-07-08 | 1999-01-21 | Chiron Corporation | Use of submicron oil-in-water emulsions with dna vaccines |
| IS4518A (is) | 1997-07-09 | 1999-01-10 | Lyfjathroun Hf, The Icelandic Bio Pharmaceutical Group | Nýtt lyfjaform fyrir bóluefni |
| GB9717953D0 (en) * | 1997-08-22 | 1997-10-29 | Smithkline Beecham Biolog | Vaccine |
| GB9718901D0 (en) | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
| TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| IL137810A0 (en) | 1998-02-12 | 2001-10-31 | American Cyanamid Co | Vaccines comprising interleukin-12 and respiratory syncytial viral antigens |
| JP2002502884A (ja) | 1998-02-12 | 2002-01-29 | アメリカン・サイアナミド・カンパニー | インターロイキン−12および単純ヘルペスウイルス抗原を含んでなるワクチン |
| US6218371B1 (en) | 1998-04-03 | 2001-04-17 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
| GB9907860D0 (en) | 1999-04-07 | 1999-06-02 | Smithkline Beecham Biolog | Novel compounds |
| ID30407A (id) | 1999-05-13 | 2001-11-29 | American Cyanamid Co | Formulasi-formulasi kombinasi bahan penambah |
-
2000
- 2000-05-12 ID IDW00200102377A patent/ID30407A/id unknown
- 2000-05-12 AU AU48473/00A patent/AU781469B2/en not_active Ceased
- 2000-05-12 CN CNB008074895A patent/CN1192799C/zh not_active Expired - Fee Related
- 2000-05-12 BR BR0010539-2A patent/BR0010539A/pt not_active Application Discontinuation
- 2000-05-12 US US10/009,473 patent/US7611721B1/en not_active Expired - Fee Related
- 2000-05-12 CZ CZ20013916A patent/CZ20013916A3/cs unknown
- 2000-05-12 SK SK1602-2001A patent/SK16022001A3/sk not_active Application Discontinuation
- 2000-05-12 CA CA2372181A patent/CA2372181C/en not_active Expired - Fee Related
- 2000-05-12 NZ NZ515322A patent/NZ515322A/xx unknown
- 2000-05-12 MX MXPA01011499A patent/MXPA01011499A/es active IP Right Grant
- 2000-05-12 EE EEP200100597A patent/EE200100597A/xx unknown
- 2000-05-12 EA EA200101198A patent/EA006233B1/ru not_active IP Right Cessation
- 2000-05-12 ES ES00930698T patent/ES2367625T3/es not_active Expired - Lifetime
- 2000-05-12 CA CA2767116A patent/CA2767116A1/en not_active Abandoned
- 2000-05-12 EP EP00930698A patent/EP1178825B1/en not_active Expired - Lifetime
- 2000-05-12 TR TR2001/03266T patent/TR200103266T2/xx unknown
- 2000-05-12 KR KR1020017014333A patent/KR100863367B1/ko not_active Expired - Fee Related
- 2000-05-12 HU HU0201220A patent/HUP0201220A3/hu unknown
- 2000-05-12 WO PCT/US2000/013156 patent/WO2000069456A2/en not_active Ceased
- 2000-05-12 IL IL14638200A patent/IL146382A0/xx active IP Right Grant
- 2000-05-12 JP JP2000617916A patent/JP4974414B2/ja not_active Expired - Fee Related
- 2000-05-12 HR HR20010839A patent/HRP20010839A2/hr not_active Application Discontinuation
- 2000-05-12 AT AT00930698T patent/ATE516046T1/de not_active IP Right Cessation
- 2000-05-12 GE GE4702A patent/GEP20053446B/en unknown
- 2000-05-12 PL PL00352312A patent/PL352312A1/xx unknown
- 2000-12-05 UA UA2001128558A patent/UA76406C2/uk unknown
-
2001
- 2001-11-07 IL IL146382A patent/IL146382A/en not_active IP Right Cessation
- 2001-11-09 BG BG106094A patent/BG106094A/xx unknown
- 2001-11-12 IS IS6156A patent/IS6156A/is unknown
- 2001-11-12 NO NO20015523A patent/NO20015523L/no not_active Application Discontinuation
-
2006
- 2006-08-08 US US11/501,904 patent/US20100233117A1/en not_active Abandoned
-
2011
- 2011-08-04 JP JP2011171095A patent/JP5230780B2/ja not_active Expired - Fee Related
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