JP2004503501A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004503501A5 JP2004503501A5 JP2002510088A JP2002510088A JP2004503501A5 JP 2004503501 A5 JP2004503501 A5 JP 2004503501A5 JP 2002510088 A JP2002510088 A JP 2002510088A JP 2002510088 A JP2002510088 A JP 2002510088A JP 2004503501 A5 JP2004503501 A5 JP 2004503501A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkenyl
- cycloalkyl
- alkynyl
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 125000000217 alkyl group Chemical group 0.000 description 18
- 125000000392 cycloalkenyl group Chemical group 0.000 description 15
- 125000003118 aryl group Chemical group 0.000 description 10
- 125000005843 halogen group Chemical group 0.000 description 9
- 125000003342 alkenyl group Chemical group 0.000 description 8
- 125000000304 alkynyl group Chemical group 0.000 description 8
- 125000000753 cycloalkyl group Chemical group 0.000 description 8
- -1 1,3,5-trithianyl Chemical group 0.000 description 7
- 229910052739 hydrogen Inorganic materials 0.000 description 7
- 229910052736 halogen Inorganic materials 0.000 description 6
- 150000002367 halogens Chemical class 0.000 description 6
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 description 5
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 description 5
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 description 5
- 229910052799 carbon Inorganic materials 0.000 description 5
- 125000001072 heteroaryl group Chemical group 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 4
- 229910052757 nitrogen Inorganic materials 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 3
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 description 2
- YBYIRNPNPLQARY-UHFFFAOYSA-N 1H-indene Natural products C1=CC=C2CC=CC2=C1 YBYIRNPNPLQARY-UHFFFAOYSA-N 0.000 description 2
- 125000002178 anthracenyl group Chemical group C1(=CC=CC2=CC3=CC=CC=C3C=C12)* 0.000 description 2
- 125000003828 azulenyl group Chemical group 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 125000003983 fluorenyl group Chemical group C1(=CC=CC=2C3=CC=CC=C3CC12)* 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 2
- 125000003454 indenyl group Chemical group C1(C=CC2=CC=CC=C12)* 0.000 description 2
- 125000006574 non-aromatic ring group Chemical group 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 229910052717 sulfur Inorganic materials 0.000 description 2
- 125000004502 1,2,3-oxadiazolyl group Chemical group 0.000 description 1
- 125000001399 1,2,3-triazolyl group Chemical group N1N=NC(=C1)* 0.000 description 1
- 125000004504 1,2,4-oxadiazolyl group Chemical group 0.000 description 1
- 125000004520 1,3,4-thiadiazolyl group Chemical group 0.000 description 1
- 125000003363 1,3,5-triazinyl group Chemical group N1=C(N=CN=C1)* 0.000 description 1
- 125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 description 1
- 125000005955 1H-indazolyl group Chemical group 0.000 description 1
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 description 1
- 125000001622 2-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C([H])=C(*)C([H])=C([H])C2=C1[H] 0.000 description 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 description 1
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 description 1
- PCJFEVUKVKQSSL-UHFFFAOYSA-N 2h-1,2,4-oxadiazol-5-one Chemical compound O=C1N=CNO1 PCJFEVUKVKQSSL-UHFFFAOYSA-N 0.000 description 1
- 125000003682 3-furyl group Chemical group O1C([H])=C([*])C([H])=C1[H] 0.000 description 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 description 1
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 description 1
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 description 1
- 125000002471 4H-quinolizinyl group Chemical group C=1(C=CCN2C=CC=CC12)* 0.000 description 1
- 206010061603 Respiratory syncytial virus infection Diseases 0.000 description 1
- 125000000641 acridinyl group Chemical group C1(=CC=CC2=NC3=CC=CC=C3C=C12)* 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 description 1
- 125000003785 benzimidazolyl group Chemical group N1=C(NC2=C1C=CC=C2)* 0.000 description 1
- 125000001164 benzothiazolyl group Chemical group S1C(=NC2=C1C=CC=C2)* 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- 125000000609 carbazolyl group Chemical group C1(=CC=CC=2C3=CC=CC=C3NC12)* 0.000 description 1
- 125000006165 cyclic alkyl group Chemical group 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 125000005842 heteroatom Chemical group 0.000 description 1
- 125000002883 imidazolyl group Chemical group 0.000 description 1
- 125000003387 indolinyl group Chemical group N1(CCC2=CC=CC=C12)* 0.000 description 1
- 125000003406 indolizinyl group Chemical group C=1(C=CN2C=CC=CC12)* 0.000 description 1
- 125000001041 indolyl group Chemical group 0.000 description 1
- 125000000904 isoindolyl group Chemical group C=1(NC=C2C=CC=CC12)* 0.000 description 1
- 125000002183 isoquinolinyl group Chemical group C1(=NC=CC2=CC=CC=C12)* 0.000 description 1
- 125000001786 isothiazolyl group Chemical group 0.000 description 1
- 125000000842 isoxazolyl group Chemical group 0.000 description 1
- 125000001624 naphthyl group Chemical group 0.000 description 1
- 125000002971 oxazolyl group Chemical group 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 125000001484 phenothiazinyl group Chemical group C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 description 1
- 125000004592 phthalazinyl group Chemical group C1(=NN=CC2=CC=CC=C12)* 0.000 description 1
- 125000001042 pteridinyl group Chemical group N1=C(N=CC2=NC=CN=C12)* 0.000 description 1
- 125000000561 purinyl group Chemical group N1=C(N=C2N=CNC2=C1)* 0.000 description 1
- 125000003373 pyrazinyl group Chemical group 0.000 description 1
- 125000003226 pyrazolyl group Chemical group 0.000 description 1
- 125000002098 pyridazinyl group Chemical group 0.000 description 1
- 125000000714 pyrimidinyl group Chemical group 0.000 description 1
- 125000000168 pyrrolyl group Chemical group 0.000 description 1
- 125000002294 quinazolinyl group Chemical group N1=C(N=CC2=CC=CC=C12)* 0.000 description 1
- 125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 description 1
- 125000001567 quinoxalinyl group Chemical group N1=C(C=NC2=CC=CC=C12)* 0.000 description 1
- 150000003536 tetrazoles Chemical class 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21144700P | 2000-06-13 | 2000-06-13 | |
| US26336301P | 2001-01-22 | 2001-01-22 | |
| PCT/US2001/014775 WO2001095910A1 (en) | 2000-06-13 | 2001-05-08 | Imidazopyridine and imidazopyrimidine antiviral agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004503501A JP2004503501A (ja) | 2004-02-05 |
| JP2004503501A5 true JP2004503501A5 (OSRAM) | 2006-06-01 |
Family
ID=26906145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002510088A Withdrawn JP2004503501A (ja) | 2000-06-13 | 2001-05-08 | イミダゾピリジンおよびイミダゾピリミジン抗ウイルス剤 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6489338B2 (OSRAM) |
| EP (1) | EP1311268A4 (OSRAM) |
| JP (1) | JP2004503501A (OSRAM) |
| KR (1) | KR20030008151A (OSRAM) |
| CN (1) | CN1436079A (OSRAM) |
| AR (1) | AR029128A1 (OSRAM) |
| AU (2) | AU2001272906B2 (OSRAM) |
| BR (1) | BR0111569A (OSRAM) |
| CA (1) | CA2412327A1 (OSRAM) |
| CZ (1) | CZ20024078A3 (OSRAM) |
| HU (1) | HUP0400766A2 (OSRAM) |
| IL (1) | IL152889A0 (OSRAM) |
| MX (1) | MXPA02012204A (OSRAM) |
| NO (1) | NO20025977L (OSRAM) |
| NZ (1) | NZ523566A (OSRAM) |
| PE (1) | PE20011348A1 (OSRAM) |
| PL (1) | PL360290A1 (OSRAM) |
| RU (1) | RU2003100828A (OSRAM) |
| UY (1) | UY26758A1 (OSRAM) |
| WO (1) | WO2001095910A1 (OSRAM) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6774134B2 (en) * | 2000-12-20 | 2004-08-10 | Bristol-Myers Squibb Company | Heterocyclic substituted 2-methyl-benzimidazole antiviral agents |
| WO2003049688A2 (en) * | 2001-12-10 | 2003-06-19 | Bristol-Myers Squibb Company | Bis hydrochloride monohydrate salt of rsv fusion inhibitor |
| US6919331B2 (en) * | 2001-12-10 | 2005-07-19 | Bristol-Myers Squibb Company | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents |
| WO2004043913A2 (en) * | 2002-11-08 | 2004-05-27 | Trimeris, Inc. | Hetero-substituted benzimidazole compounds and antiviral uses thereof |
| WO2005016275A2 (en) * | 2003-08-05 | 2005-02-24 | 3M Innovative Properties Company | Formulations containing an immune response modifier |
| EP1682547B1 (en) | 2003-10-30 | 2012-10-24 | Boehringer Ingelheim (Canada) Ltd. | Rsv polymerase inhibitors |
| NZ551468A (en) | 2003-12-24 | 2010-05-28 | Biota Scient Management | Polycyclic agents for the treatment of respiratory syncytial virus infections |
| GB0406282D0 (en) * | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Therapeutic compounds |
| GB0406279D0 (en) * | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Therapeutic compounds |
| CN101027303A (zh) | 2004-07-27 | 2007-08-29 | 吉里德科学公司 | 咪唑并[4，5－d]嘧啶类、其应用和制备方法 |
| CN101203507B (zh) | 2005-06-20 | 2012-05-23 | 泰博特克药品有限公司 | 2-取代的苯并咪唑 |
| US8034835B2 (en) | 2005-06-20 | 2011-10-11 | Tibotec Pharmaceuticals Ltd. | 1-[[2-amino-3-(substituted alkyl)-3H-benzimidazolyl[methyl]-3-substituted-1,3-dihydro-benzoimidazol-2-ones and structural analogs |
| JP5094716B2 (ja) | 2005-06-20 | 2012-12-12 | テイボテク・フアーマシユーチカルズ | ヘテロシクリルアミノアルキル置換ベンズイミダゾール |
| TWI423972B (zh) | 2006-09-28 | 2014-01-21 | Biota Scient Management | 治療呼吸系融合細胞病毒感染之多環劑 |
| WO2009084544A1 (ja) * | 2007-12-27 | 2009-07-09 | Idemitsu Kosan Co., Ltd. | 含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子 |
| US20100278835A1 (en) | 2009-03-10 | 2010-11-04 | Astrazeneca Uk Limited | Novel compounds 660 |
| RU2407738C1 (ru) * | 2009-07-03 | 2010-12-27 | Общество с ограниченной ответственностью "Интеллектуальный Диалог" | Противовирусный активный компонент, фармацевтическая композиция, лекарственное средство, способ лечения вирусных заболеваний |
| TWI508968B (zh) | 2010-02-08 | 2015-11-21 | Biota Scient Management | 用於治療呼吸道融合性病毒感染的化合物 |
| WO2011115150A1 (ja) * | 2010-03-18 | 2011-09-22 | 興和株式会社 | ベンゾチアジン化合物の製造方法 |
| US8796303B2 (en) | 2010-11-26 | 2014-08-05 | Biota Scientific Management Pty Ltd. | Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections |
| TWI527814B (zh) | 2010-12-16 | 2016-04-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類 |
| TWI501967B (zh) | 2010-12-16 | 2015-10-01 | Janssen R&D Ireland | 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類 |
| TWI541241B (zh) * | 2010-12-16 | 2016-07-11 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類 |
| TWI530495B (zh) * | 2010-12-16 | 2016-04-21 | 健生科學愛爾蘭無限公司 | 苯并咪唑呼吸道融合病毒抑制劑 |
| TWI515187B (zh) | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| CN103860538B (zh) * | 2011-03-23 | 2016-03-02 | 上海市第一人民医院 | 靶向人La蛋白的先导化合物及其在制备抗乙型肝炎病毒的药物中的用途 |
| WO2013186229A1 (en) * | 2012-06-11 | 2013-12-19 | Ucb Pharma S.A. | Tnf -alpha modulating benzimidazoles |
| KR102092612B1 (ko) * | 2012-06-15 | 2020-03-25 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 호흡기 합포체 바이러스의 항바이러스제로서의 헤테로사이클로 치환된 1,3-디하이드로-2h-벤즈이미다졸-2-온 유도체 |
| CA2873916A1 (en) * | 2012-06-15 | 2013-12-19 | Janssen R&D Ireland | 4-substituted 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with benzimidazoles as respiratory syncytial virus antivira agents |
| JP2015523350A (ja) * | 2012-06-15 | 2015-08-13 | ヤンセン・アールアンドデイ・アイルランド | Ｒｓウイルス抗ウイルス薬としての、ベンゾイミダゾールによって置換された新規１，３−ジヒドロ−２ｈ−ベンゾイミダゾル−２−オン誘導体 |
| WO2013186335A1 (en) * | 2012-06-15 | 2013-12-19 | Janssen R&D Ireland | 1,3 -dihydro-2h-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents |
| MY172021A (en) * | 2012-10-16 | 2019-11-12 | Janssen Sciences Ireland Uc | Rsv antiviral compounds |
| JP2016145155A (ja) * | 2013-04-30 | 2016-08-12 | 日本農薬株式会社 | フタルアミド誘導体及び該誘導体を含有する農園芸用殺虫剤並びにその使用方法 |
| BR112016009757A8 (pt) * | 2013-10-29 | 2018-01-30 | Medivir Ab | “inibidores do vírus sincicial respiratório com base em quinazolina” |
| WO2015065336A1 (en) * | 2013-10-29 | 2015-05-07 | Medivir Ab | Respiratory syncytial virus inhibitors |
| CA3008653A1 (en) * | 2015-10-14 | 2017-04-20 | Zibo Biopolar Changsheng Pharmaceutical Co. Ltd. | Bruton's tyrosine kinase inhibitors |
| WO2019046364A1 (en) * | 2017-08-29 | 2019-03-07 | Emory University | INHIBITORS OF SYNCYTIAL RESPIRATORY VIRUS (RSV) REPLICATION AND USES THEREOF |
| MX2022005257A (es) * | 2019-10-30 | 2022-06-09 | Janssen Sciences Ireland Unlimited Co | Sintesis de 3-({5-cloro-1-[3-(metilsulfonil)propil]-1h-indol-2-il} metil)-1-(2,2,2-trifluoroetil)-1,3-dihidro-2h-imidazo[4,5-c]pirid in-2-ona. |
| CN114630820B (zh) * | 2019-10-30 | 2023-10-31 | 杨森科学爱尔兰无限公司 | 3-硝基-n-(2,2,2-三氟乙基)-4-吡啶胺的合成 |
| EP4165034A1 (en) | 2020-06-11 | 2023-04-19 | Janssen Sciences Ireland Unlimited Company | Hemi (l)-tartrate forms of 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1h-indol-2 yl} methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2h-imidazo[4,5-c]pyridin-2-one and pharmaceutical compositions comprising the same |
| WO2022184606A1 (en) * | 2021-03-01 | 2022-09-09 | Janssen Sciences Ireland Unlimited Company | Synthesis of rilematovir |
| JP2025502943A (ja) * | 2022-01-28 | 2025-01-30 | インシリコ メディシン アイピー リミテッド | エクトヌクレオチドピロホスファターゼ－ホスホジエステラーゼ１（ｅｎｐｐ１）阻害剤およびその使用 |
| WO2025026383A1 (en) * | 2023-08-02 | 2025-02-06 | Insilico Medicine Ip Limited | Crytsalline forms of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp1) inhibitors and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4324794A (en) | 1980-08-26 | 1982-04-13 | Research Triangle Institute | Inhibition of respiratory syncytial virus-induced cell fusion by amidino compounds |
| DK154078C (da) | 1981-02-06 | 1989-05-22 | Ucb Sa | Analogifremgangsmaade til fremstilling af 2-(2-(4-(diphenyl-methyl)-1-piperazinyl)ethoxy)-acetamider eller syreadditionssalte heraf |
| US5256668A (en) | 1993-03-17 | 1993-10-26 | American Home Products Corporation | Aminopyrimidine derivatives as antiviral agents for respiratory syncytial virus |
| BR9700939A (pt) | 1996-02-13 | 1998-09-01 | American Cyanamid Co | Compostos aniônicos contendo traiazina úteis como agentes antivirais |
| BR9908522A (pt) | 1998-01-29 | 2001-10-02 | Viropharma Inc | Composto, pró-droga, intermediário para a preparação de um composto, composição farmacêutica, processos para tratar e prevenir infecção por pneumovìrus, para tratar células em cultura, para tratar materiais biológicos, e, para preparar um composto |
| CA2338147A1 (en) | 1998-07-20 | 2000-02-03 | Kuo-Long Yu | Substituted benzimidazole antiviral agents |
| HRP20010934A2 (en) | 1999-06-28 | 2003-06-30 | Janssen Pharmaceutica Nv | Respiratory syncytial virus replication inhibitors |
-
2001
- 2001-04-23 US US09/840,279 patent/US6489338B2/en not_active Expired - Fee Related
- 2001-05-08 JP JP2002510088A patent/JP2004503501A/ja not_active Withdrawn
- 2001-05-08 EP EP01952114A patent/EP1311268A4/en not_active Withdrawn
- 2001-05-08 CN CN01811136A patent/CN1436079A/zh active Pending
- 2001-05-08 CZ CZ20024078A patent/CZ20024078A3/cs unknown
- 2001-05-08 AU AU2001272906A patent/AU2001272906B2/en not_active Ceased
- 2001-05-08 NZ NZ523566A patent/NZ523566A/en unknown
- 2001-05-08 KR KR1020027016924A patent/KR20030008151A/ko not_active Ceased
- 2001-05-08 AU AU7290601A patent/AU7290601A/xx active Pending
- 2001-05-08 IL IL15288901A patent/IL152889A0/xx unknown
- 2001-05-08 CA CA002412327A patent/CA2412327A1/en not_active Abandoned
- 2001-05-08 HU HU0400766A patent/HUP0400766A2/hu unknown
- 2001-05-08 BR BR0111569-3A patent/BR0111569A/pt not_active IP Right Cessation
- 2001-05-08 MX MXPA02012204A patent/MXPA02012204A/es unknown
- 2001-05-08 RU RU2003100828/15A patent/RU2003100828A/ru not_active Application Discontinuation
- 2001-05-08 PL PL36029001A patent/PL360290A1/xx not_active Application Discontinuation
- 2001-05-08 WO PCT/US2001/014775 patent/WO2001095910A1/en not_active Ceased
- 2001-06-11 UY UY26758A patent/UY26758A1/es not_active Application Discontinuation
- 2001-06-12 AR ARP010102772A patent/AR029128A1/es unknown
- 2001-06-13 PE PE2001000559A patent/PE20011348A1/es not_active Application Discontinuation
-
2002
- 2002-12-12 NO NO20025977A patent/NO20025977L/no not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004503501A5 (OSRAM) | ||
| RU2003100828A (ru) | Имидазопиридиновые и имидазопиримидиновые антивирусные агенты | |
| RU2003134544A (ru) | Амиды антраниловой кислоты, способы их получения, их применение в качестве антиаритмических средств, а также содержащие их фармацевтические композиции | |
| RU2004100302A (ru) | Амиды антраниловой кислоты с гетероарилсульфонильной боковой цепью, способ их получения, их применение в качестве лекарственного или диагностического средства, а также содержащие их фармацевтические композиции | |
| JP2004533464A5 (OSRAM) | ||
| JP6021805B2 (ja) | 腫瘍治療剤 | |
| JP2008543886A5 (OSRAM) | ||
| RU2005120780A (ru) | Соединения с конденсированным 1,3-дигидроимидазольным циклом | |
| RU2001132139A (ru) | Имидазохинолины с сульфонамидными или сульфамидным замещением | |
| CA2472372A1 (en) | Hydroxynaphthyridinone carboxamides useful as hiv integrase inhibitors | |
| JP2006507326A5 (OSRAM) | ||
| JP2007507494A5 (OSRAM) | ||
| HRP20211046T1 (hr) | Upotreba derivata benzimidazola kod noćnog proboja kiseline | |
| JP2008534453A5 (OSRAM) | ||
| SK165598A3 (en) | Use of h+,k+ -atpase inhibitor, pharmaceutical composition containing the same and its use | |
| RU2002100058A (ru) | Кристаллические производные 1-метилкарбапенема | |
| JP2005525398A5 (OSRAM) | ||
| RU2003118411A (ru) | Кристаллические производные 1-метилкарбапенема | |
| JP2009541387A5 (OSRAM) | ||
| JP2011526286A5 (OSRAM) | ||
| JP2025027020A (ja) | 患者において血清リン酸塩を低下させるための組み合わせ | |
| JP2002539089A5 (OSRAM) | ||
| JP2002529497A5 (OSRAM) | ||
| RU2222538C2 (ru) | Оптически активное производное пиридил-4н-1,2,4-оксадиазина и фармацевтическая композиция | |
| JP2012500222A (ja) | 金属酵素阻害剤の設計および開発のための組成物および方法 |