IL152889A0 - Imidazopyridine and imidazopyrimidine derivatives and pharmaceutical compositions containing the same - Google Patents
Imidazopyridine and imidazopyrimidine derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- IL152889A0 IL152889A0 IL15288901A IL15288901A IL152889A0 IL 152889 A0 IL152889 A0 IL 152889A0 IL 15288901 A IL15288901 A IL 15288901A IL 15288901 A IL15288901 A IL 15288901A IL 152889 A0 IL152889 A0 IL 152889A0
- Authority
- IL
- Israel
- Prior art keywords
- imidazopyridine
- same
- pharmaceutical compositions
- compositions containing
- imidazopyrimidine derivatives
- Prior art date
Links
- GAMYYCRTACQSBR-UHFFFAOYSA-N 4-azabenzimidazole Chemical compound C1=CC=C2NC=NC2=N1 GAMYYCRTACQSBR-UHFFFAOYSA-N 0.000 title 1
- 150000005237 imidazopyrimidines Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21144700P | 2000-06-13 | 2000-06-13 | |
| US26336301P | 2001-01-22 | 2001-01-22 | |
| PCT/US2001/014775 WO2001095910A1 (en) | 2000-06-13 | 2001-05-08 | Imidazopyridine and imidazopyrimidine antiviral agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL152889A0 true IL152889A0 (en) | 2003-06-24 |
Family
ID=26906145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15288901A IL152889A0 (en) | 2000-06-13 | 2001-05-08 | Imidazopyridine and imidazopyrimidine derivatives and pharmaceutical compositions containing the same |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6489338B2 (OSRAM) |
| EP (1) | EP1311268A4 (OSRAM) |
| JP (1) | JP2004503501A (OSRAM) |
| KR (1) | KR20030008151A (OSRAM) |
| CN (1) | CN1436079A (OSRAM) |
| AR (1) | AR029128A1 (OSRAM) |
| AU (2) | AU7290601A (OSRAM) |
| BR (1) | BR0111569A (OSRAM) |
| CA (1) | CA2412327A1 (OSRAM) |
| CZ (1) | CZ20024078A3 (OSRAM) |
| HU (1) | HUP0400766A2 (OSRAM) |
| IL (1) | IL152889A0 (OSRAM) |
| MX (1) | MXPA02012204A (OSRAM) |
| NO (1) | NO20025977L (OSRAM) |
| NZ (1) | NZ523566A (OSRAM) |
| PE (1) | PE20011348A1 (OSRAM) |
| PL (1) | PL360290A1 (OSRAM) |
| RU (1) | RU2003100828A (OSRAM) |
| UY (1) | UY26758A1 (OSRAM) |
| WO (1) | WO2001095910A1 (OSRAM) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6774134B2 (en) * | 2000-12-20 | 2004-08-10 | Bristol-Myers Squibb Company | Heterocyclic substituted 2-methyl-benzimidazole antiviral agents |
| US6919331B2 (en) * | 2001-12-10 | 2005-07-19 | Bristol-Myers Squibb Company | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents |
| PL369432A1 (en) | 2001-12-10 | 2005-04-18 | Bristol-Myers Squibb Company | Bis hydrochloride monohydrate salt of rsv fusion inhibitor |
| WO2004043913A2 (en) * | 2002-11-08 | 2004-05-27 | Trimeris, Inc. | Hetero-substituted benzimidazole compounds and antiviral uses thereof |
| JP2007501251A (ja) * | 2003-08-05 | 2007-01-25 | スリーエム イノベイティブ プロパティズ カンパニー | 免疫応答調節剤化合物を使用する感染予防 |
| EP1682547B1 (en) | 2003-10-30 | 2012-10-24 | Boehringer Ingelheim (Canada) Ltd. | Rsv polymerase inhibitors |
| CA2551178C (en) | 2003-12-24 | 2012-11-06 | Biota Scientific Management Pty Ltd | Polycyclic agents for the treatment of respiratory syncytial virus infections |
| GB0406279D0 (en) * | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Therapeutic compounds |
| GB0406282D0 (en) * | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Therapeutic compounds |
| KR101238430B1 (ko) | 2004-07-27 | 2013-02-28 | 길리애드 사이언시즈, 인코포레이티드 | 이미다조［4,5-ｄ］피리미딘, 그들의 용도 및 제조방법 |
| CA2612264C (en) | 2005-06-20 | 2014-09-23 | Tibotec Pharmaceuticals Ltd. | Heterocyclylaminoalkyl substituted benzimidazoles |
| BRPI0612317B8 (pt) | 2005-06-20 | 2021-05-25 | Janssen R & D Ireland | benzimidazóis 2-substituídos, seu processo de preparação e composição farmacêutica |
| ATE529424T1 (de) | 2005-06-20 | 2011-11-15 | Tibotec Pharm Ltd | 1-ää2-amino-3-(substituiertes alkyl)-3h- benzimidazolylümethylü-3-substituierte-1,3- dihydrobenzimidazol-2-one als replikationshemmer des respiratorischen syncytialvirus |
| TWI423972B (zh) | 2006-09-28 | 2014-01-21 | Biota Scient Management | 治療呼吸系融合細胞病毒感染之多環劑 |
| WO2009084544A1 (ja) * | 2007-12-27 | 2009-07-09 | Idemitsu Kosan Co., Ltd. | 含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子 |
| WO2010103306A1 (en) | 2009-03-10 | 2010-09-16 | Astrazeneca Uk Limited | Benzimidazole derivatives and their use as antivaral agents |
| RU2407738C1 (ru) * | 2009-07-03 | 2010-12-27 | Общество с ограниченной ответственностью "Интеллектуальный Диалог" | Противовирусный активный компонент, фармацевтическая композиция, лекарственное средство, способ лечения вирусных заболеваний |
| TWI508968B (zh) | 2010-02-08 | 2015-11-21 | Biota Scient Management | 用於治療呼吸道融合性病毒感染的化合物 |
| JPWO2011115150A1 (ja) * | 2010-03-18 | 2013-07-04 | 興和株式会社 | ベンゾチアジン化合物の製造方法 |
| US8796303B2 (en) | 2010-11-26 | 2014-08-05 | Biota Scientific Management Pty Ltd. | Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections |
| TWI530495B (zh) * | 2010-12-16 | 2016-04-21 | 健生科學愛爾蘭無限公司 | 苯并咪唑呼吸道融合病毒抑制劑 |
| TWI515187B (zh) * | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| TWI541241B (zh) | 2010-12-16 | 2016-07-11 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類 |
| TWI501967B (zh) * | 2010-12-16 | 2015-10-01 | Janssen R&D Ireland | 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類 |
| TWI527814B (zh) | 2010-12-16 | 2016-04-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類 |
| CN103893173B (zh) * | 2011-03-23 | 2016-02-24 | 上海市第一人民医院 | 靶向人La蛋白的先导化合物及其在制备抗乙型肝炎病毒的药物中的用途 |
| ES2675583T3 (es) * | 2012-06-11 | 2018-07-11 | Ucb Biopharma Sprl | Bencimidazoles moduladores de TNF-alfa |
| KR102092612B1 (ko) * | 2012-06-15 | 2020-03-25 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 호흡기 합포체 바이러스의 항바이러스제로서의 헤테로사이클로 치환된 1,3-디하이드로-2h-벤즈이미다졸-2-온 유도체 |
| AU2013276521A1 (en) * | 2012-06-15 | 2014-12-04 | Janssen Sciences Ireland Uc | 1,3 -dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents |
| AU2013276518A1 (en) * | 2012-06-15 | 2014-12-04 | Janssen Sciences Ireland Uc | 4 - substituted 1, 3 - dihydro - 2H - benzimidazol - 2 - one derivatives substituted with benzimidazoles as respiratory syncytial virus antiviral agents |
| EA201590020A1 (ru) * | 2012-06-15 | 2015-03-31 | ЯНССЕН Ар ЭНД Ди АЙРЛЭНД | Новые производные 1,3-дигидро-2h-бензимидазол-2-она, замещенные бензимидазолами, в качестве противовирусных средств против респираторного синцитиального вируса |
| EP2909195B1 (en) * | 2012-10-16 | 2017-06-14 | Janssen Sciences Ireland UC | Rsv antiviral compounds |
| JP2016145155A (ja) * | 2013-04-30 | 2016-08-12 | 日本農薬株式会社 | フタルアミド誘導体及び該誘導体を含有する農園芸用殺虫剤並びにその使用方法 |
| HK1219482A1 (zh) * | 2013-10-29 | 2017-04-07 | 美迪维尔公司 | 基於喹唑啉的呼吸道合胞病毒抑制剂 |
| WO2015065336A1 (en) * | 2013-10-29 | 2015-05-07 | Medivir Ab | Respiratory syncytial virus inhibitors |
| WO2017066014A1 (en) * | 2015-10-14 | 2017-04-20 | Sunnylife Pharma Inc. | Bruton's tyrosine kinase inhibitors |
| WO2019046364A1 (en) * | 2017-08-29 | 2019-03-07 | Emory University | INHIBITORS OF SYNCYTIAL RESPIRATORY VIRUS (RSV) REPLICATION AND USES THEREOF |
| EP4051663B1 (en) | 2019-10-30 | 2024-02-21 | Janssen Sciences Ireland Unlimited Company | Synthesis of 3-nitro-n-(2,2,2-trifluoroethyl)-4-pyridinamine |
| CN114630828B (zh) * | 2019-10-30 | 2023-10-31 | 杨森科学爱尔兰无限公司 | 一种rsv抑制化合物的合成 |
| US12145933B2 (en) | 2020-06-11 | 2024-11-19 | Janssen Sciences Ireland Unlimited Company | Hemi (L)-tartrate forms of 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethy)-1,3-dihydro-2H-imidazo[4,5-C]pyridin-2-one and pharmaceutical compositions comprising the same |
| WO2022184606A1 (en) * | 2021-03-01 | 2022-09-09 | Janssen Sciences Ireland Unlimited Company | Synthesis of rilematovir |
| CA3247162A1 (en) * | 2022-01-28 | 2023-08-03 | Insilico Medicine Ip Limited | Ectunocleotide pyrophosphatase-phosphodiesterase 1 (ENPP1) inhibitors and their uses |
| WO2025026383A1 (en) * | 2023-08-02 | 2025-02-06 | Insilico Medicine Ip Limited | Crytsalline forms of ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp1) inhibitors and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4324794A (en) | 1980-08-26 | 1982-04-13 | Research Triangle Institute | Inhibition of respiratory syncytial virus-induced cell fusion by amidino compounds |
| FI75816C (fi) | 1981-02-06 | 1988-08-08 | Ucb Sa | Foerfarande foer framstaellning av terapeutiskt aktiv 2-/4-(difenylmetyl)-1-piperazinyl/-aettiksyror eller dess amid. |
| US5256668A (en) | 1993-03-17 | 1993-10-26 | American Home Products Corporation | Aminopyrimidine derivatives as antiviral agents for respiratory syncytial virus |
| BR9700939A (pt) | 1996-02-13 | 1998-09-01 | American Cyanamid Co | Compostos aniônicos contendo traiazina úteis como agentes antivirais |
| NZ505894A (en) | 1998-01-29 | 2002-12-20 | Viropharma Inc | Methylenebisbenzaldehyde derivatives, methylidynetrisphenol derivative and pharmaceuticals thereof; useful for treating or preventing pneumovirus infection and associated diseases |
| WO2000004900A1 (en) | 1998-07-20 | 2000-02-03 | Bristol-Myers Squibb Company | Substituted benzimidazole antiviral agents |
| EE04592B1 (et) | 1999-06-28 | 2006-02-15 | Janssen Pharmaceutica N.V. | Respiratoorse süntsütiaalviiruse replikatsiooni inhibiitorid, nende valmistamismeetod, kasutamine ja vaheühendid, farmatseutiline kompositsioon ja selle valmistamismeetod ning produkt |
-
2001
- 2001-04-23 US US09/840,279 patent/US6489338B2/en not_active Expired - Fee Related
- 2001-05-08 IL IL15288901A patent/IL152889A0/xx unknown
- 2001-05-08 KR KR1020027016924A patent/KR20030008151A/ko not_active Ceased
- 2001-05-08 MX MXPA02012204A patent/MXPA02012204A/es unknown
- 2001-05-08 CN CN01811136A patent/CN1436079A/zh active Pending
- 2001-05-08 NZ NZ523566A patent/NZ523566A/en unknown
- 2001-05-08 PL PL36029001A patent/PL360290A1/xx not_active Application Discontinuation
- 2001-05-08 CZ CZ20024078A patent/CZ20024078A3/cs unknown
- 2001-05-08 HU HU0400766A patent/HUP0400766A2/hu unknown
- 2001-05-08 WO PCT/US2001/014775 patent/WO2001095910A1/en not_active Ceased
- 2001-05-08 AU AU7290601A patent/AU7290601A/xx active Pending
- 2001-05-08 JP JP2002510088A patent/JP2004503501A/ja not_active Withdrawn
- 2001-05-08 RU RU2003100828/15A patent/RU2003100828A/ru not_active Application Discontinuation
- 2001-05-08 BR BR0111569-3A patent/BR0111569A/pt not_active IP Right Cessation
- 2001-05-08 CA CA002412327A patent/CA2412327A1/en not_active Abandoned
- 2001-05-08 EP EP01952114A patent/EP1311268A4/en not_active Withdrawn
- 2001-05-08 AU AU2001272906A patent/AU2001272906B2/en not_active Ceased
- 2001-06-11 UY UY26758A patent/UY26758A1/es not_active Application Discontinuation
- 2001-06-12 AR ARP010102772A patent/AR029128A1/es unknown
- 2001-06-13 PE PE2001000559A patent/PE20011348A1/es not_active Application Discontinuation
-
2002
- 2002-12-12 NO NO20025977A patent/NO20025977L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA02012204A (es) | 2003-10-15 |
| US6489338B2 (en) | 2002-12-03 |
| HUP0400766A2 (hu) | 2004-07-28 |
| NO20025977L (no) | 2003-01-29 |
| JP2004503501A (ja) | 2004-02-05 |
| PE20011348A1 (es) | 2002-02-07 |
| AU7290601A (en) | 2001-12-24 |
| KR20030008151A (ko) | 2003-01-24 |
| CZ20024078A3 (cs) | 2003-08-13 |
| EP1311268A1 (en) | 2003-05-21 |
| CA2412327A1 (en) | 2001-12-20 |
| WO2001095910A1 (en) | 2001-12-20 |
| NZ523566A (en) | 2004-08-27 |
| NO20025977D0 (no) | 2002-12-12 |
| RU2003100828A (ru) | 2004-06-27 |
| UY26758A1 (es) | 2002-01-31 |
| EP1311268A4 (en) | 2004-06-30 |
| CN1436079A (zh) | 2003-08-13 |
| AU2001272906B2 (en) | 2004-08-26 |
| AR029128A1 (es) | 2003-06-04 |
| BR0111569A (pt) | 2003-04-29 |
| PL360290A1 (en) | 2004-09-06 |
| US20020016309A1 (en) | 2002-02-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL152889A0 (en) | Imidazopyridine and imidazopyrimidine derivatives and pharmaceutical compositions containing the same | |
| IL150734A0 (en) | Azaindole derivatives and pharmaceutical compositions containing the same | |
| IL156354A0 (en) | Pyridoindole derivatives and pharmaceutical compositions containing the same | |
| IL152451A0 (en) | 2-chloro-2-nitrophenylcarboxamide derivatives and pharmaceutical compositions containing the same | |
| HUP0301178A3 (en) | Glucopyranosyloxybenzylbenzene derivatives and pharmaceutical compositions containing the same | |
| IL153123A0 (en) | N-ureidoheterocycloalkyl-piperidine derivatives and pharmaceutical compositions containing the same | |
| IL151952A0 (en) | Aminopyridine derivatives and pharmaceutical compositions containing the same | |
| IL144977A0 (en) | Pyrrolotriazine derivatives and pharmaceutical compositions containing the same | |
| HUP0203895A3 (en) | Substituted azaindoles and pharmaceutical compositions containing them and their use | |
| HUP0100179A3 (en) | Imidazopyrimidine and imidazopyridine derivatives and pharmaceutical compositions thereof | |
| IL156558A0 (en) | Novel quinuclidine derivatives and medicinal compositions containing the same | |
| EG24066A (en) | Novel quinuclidine derivatives and medicinal compositions containing the same | |
| IL166232A0 (en) | Azaindole derivatives and pharmaceutical compositions containing the same | |
| IL152490A0 (en) | Pyridine derivatives and pharmaceutical compositions containing the same | |
| HUP0400784A3 (en) | Bicyclic heterocondensated pyrrolcarboxamide derivatives, their use and pharmaceutical compositions containing them | |
| IL161616A0 (en) | Indazolypyrrolotriazine derivatives and pharmaceutical compositions containing the same | |
| IL150224A0 (en) | Lipopeptides and pharmaceutical compositions containing the same | |
| IL150223A0 (en) | Lipopeptides and pharmaceutical compositions containing the same | |
| IL158044A0 (en) | Cyclopropylindole derivatives and pharmaceutical compositions containing the same | |
| IL158300A0 (en) | Bisarylimidazol derivatives and pharmaceutical compositions containing the same | |
| IL152718A0 (en) | Piperidine derivatives and pharmaceutical compositions containing the same | |
| IL152094A0 (en) | Ecteinascidin derivatives and pharmaceutical compositions containing the same | |
| IL156812A0 (en) | Phthalazinone-piperidino derivatives and pharmaceutical compositions containing the same | |
| IL155067A0 (en) | (dihydro) isoquinoline derivatives and pharmaceutical compositions containing the same | |
| IL147214A0 (en) | 1-methylcarbapenem derivatives and pharmaceutical compositions containing the same |