JP2003528827A5 - - Google Patents

Info

Publication number

JP2003528827A5

JP2003528827A5 JP2001563131A JP2001563131A JP2003528827A5 JP 2003528827 A5 JP2003528827 A5 JP 2003528827A5 JP 2001563131 A JP2001563131 A JP 2001563131A JP 2001563131 A JP2001563131 A JP 2001563131A JP 2003528827 A5 JP2003528827 A5 JP 2003528827A5

Authority

JP

Japan

Prior art keywords

casein

peptide

derived

preventing

treating

Prior art date

2001-03-01

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 108090000765 processed proteins & peptides Proteins 0.000 claims 125
• 102000009366 Alpha-s1 casein Human genes 0.000 claims 63
• 108050000244 Alpha-s1 casein Proteins 0.000 claims 63
• 239000005018 casein Substances 0.000 claims 51
• BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims 51
• 235000021240 caseins Nutrition 0.000 claims 51
• 238000002360 preparation method Methods 0.000 claims 48
• 238000004519 manufacturing process Methods 0.000 claims 37
• 238000000034 method Methods 0.000 claims 30
• 230000001939 inductive effect Effects 0.000 claims 28
• 239000008194 pharmaceutical composition Substances 0.000 claims 25
• 210000004369 blood Anatomy 0.000 claims 23
• 239000008280 blood Substances 0.000 claims 23
• 210000000130 stem cell Anatomy 0.000 claims 23
• 239000003814 drug Substances 0.000 claims 22
• 239000003937 drug carrier Substances 0.000 claims 21
• 239000004480 active ingredient Substances 0.000 claims 20
• 210000001185 bone marrow Anatomy 0.000 claims 20
• 230000006378 damage Effects 0.000 claims 15
• 238000002054 transplantation Methods 0.000 claims 11
• 238000010322 bone marrow transplantation Methods 0.000 claims 10
• 206010012601 diabetes mellitus Diseases 0.000 claims 10
• 210000003958 hematopoietic stem cell Anatomy 0.000 claims 10
• 230000002265 prevention Effects 0.000 claims 10
• 208000030507 AIDS Diseases 0.000 claims 5
• 201000010000 Agranulocytosis Diseases 0.000 claims 5
• 208000023275 Autoimmune disease Diseases 0.000 claims 5
• 206010018687 Granulocytopenia Diseases 0.000 claims 5
• 208000031226 Hyperlipidaemia Diseases 0.000 claims 5
• 206010033661 Pancytopenia Diseases 0.000 claims 5
• 208000036142 Viral infection Diseases 0.000 claims 5
• 230000000735 allogeneic effect Effects 0.000 claims 5
• 230000004663 cell proliferation Effects 0.000 claims 5
• 230000004069 differentiation Effects 0.000 claims 5
• 201000010099 disease Diseases 0.000 claims 5
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
• 230000002708 enhancing effect Effects 0.000 claims 5
• 230000010437 erythropoiesis Effects 0.000 claims 5
• 230000011132 hemopoiesis Effects 0.000 claims 5
• 208000015181 infectious disease Diseases 0.000 claims 5
• 210000000265 leukocyte Anatomy 0.000 claims 5
• 210000003593 megakaryocyte Anatomy 0.000 claims 5
• 210000005259 peripheral blood Anatomy 0.000 claims 5
• 239000011886 peripheral blood Substances 0.000 claims 5
• 230000035755 proliferation Effects 0.000 claims 5
• 238000011127 radiochemotherapy Methods 0.000 claims 5
• 238000011476 stem cell transplantation Methods 0.000 claims 5
• 206010043554 thrombocytopenia Diseases 0.000 claims 5
• 230000009385 viral infection Effects 0.000 claims 5
• 230000003612 virological effect Effects 0.000 claims 5
• 239000012634 fragment Substances 0.000 claims 3
• 238000013467 fragmentation Methods 0.000 claims 3
• 238000006062 fragmentation reaction Methods 0.000 claims 3
• 125000003275 alpha amino acid group Chemical group 0.000 claims 2
• 102000004196 processed proteins & peptides Human genes 0.000 claims 1