JP2003518124A - ペプチドβ−ターン構造の模倣化合物及びその製法 - Google Patents
ペプチドβ−ターン構造の模倣化合物及びその製法Info
- Publication number
- JP2003518124A JP2003518124A JP2001547107A JP2001547107A JP2003518124A JP 2003518124 A JP2003518124 A JP 2003518124A JP 2001547107 A JP2001547107 A JP 2001547107A JP 2001547107 A JP2001547107 A JP 2001547107A JP 2003518124 A JP2003518124 A JP 2003518124A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heteroatoms
- product
- phenyl
- unsubstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17282399P | 1999-12-21 | 1999-12-21 | |
| US60/172,823 | 1999-12-21 | ||
| PCT/US2000/034832 WO2001046197A1 (en) | 1999-12-21 | 2000-12-20 | PEPTIDE β-TURN MIMETIC COMPOUNDS AND PROCESSES FOR MAKING THEM |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2003518124A true JP2003518124A (ja) | 2003-06-03 |
Family
ID=22629385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001547107A Withdrawn JP2003518124A (ja) | 1999-12-21 | 2000-12-20 | ペプチドβ−ターン構造の模倣化合物及びその製法 |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1240169A1 (hu) |
| JP (1) | JP2003518124A (hu) |
| KR (1) | KR20020062352A (hu) |
| CN (1) | CN1413214A (hu) |
| AU (1) | AU2286401A (hu) |
| BR (1) | BR0016518A (hu) |
| CA (1) | CA2393759A1 (hu) |
| CO (1) | CO5251420A1 (hu) |
| CZ (1) | CZ20022110A3 (hu) |
| HU (1) | HUP0300100A2 (hu) |
| IL (1) | IL149834A0 (hu) |
| MX (1) | MXPA02006330A (hu) |
| NO (1) | NO20022953D0 (hu) |
| PE (1) | PE20010955A1 (hu) |
| PL (1) | PL355971A1 (hu) |
| WO (1) | WO2001046197A1 (hu) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022515422A (ja) * | 2018-12-27 | 2022-02-18 | ホロスメディック | 新規の化合物およびこれを含む抗癌活性増進用薬学組成物 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020139044A1 (ko) * | 2018-12-27 | 2020-07-02 | 홀로스메딕 주식회사 | 신규한 화합물 및 이를 포함하는 항암 활성 증진용 약학 조성물 |
| AU2020374208B2 (en) * | 2019-10-31 | 2024-03-14 | Holosmedic | Novel compound and pharmaceutical composition for prevention or treatment of cancer comprising same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5929237A (en) * | 1995-10-27 | 1999-07-27 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| US6013458A (en) * | 1995-10-27 | 2000-01-11 | Molecumetics, Ltd. | Reverse-turn mimetics and methods relating thereto |
-
2000
- 2000-12-19 PE PE2000001366A patent/PE20010955A1/es not_active Application Discontinuation
- 2000-12-20 CZ CZ20022110A patent/CZ20022110A3/cs unknown
- 2000-12-20 MX MXPA02006330A patent/MXPA02006330A/es unknown
- 2000-12-20 JP JP2001547107A patent/JP2003518124A/ja not_active Withdrawn
- 2000-12-20 WO PCT/US2000/034832 patent/WO2001046197A1/en not_active Application Discontinuation
- 2000-12-20 AU AU22864/01A patent/AU2286401A/en not_active Abandoned
- 2000-12-20 KR KR1020027007839A patent/KR20020062352A/ko not_active Application Discontinuation
- 2000-12-20 EP EP00986673A patent/EP1240169A1/en not_active Withdrawn
- 2000-12-20 HU HU0300100A patent/HUP0300100A2/hu unknown
- 2000-12-20 IL IL14983400A patent/IL149834A0/xx unknown
- 2000-12-20 CN CN00817604A patent/CN1413214A/zh active Pending
- 2000-12-20 BR BR0016518-2A patent/BR0016518A/pt not_active IP Right Cessation
- 2000-12-20 PL PL00355971A patent/PL355971A1/xx not_active Application Discontinuation
- 2000-12-20 CA CA002393759A patent/CA2393759A1/en not_active Abandoned
- 2000-12-21 CO CO00097142A patent/CO5251420A1/es not_active Application Discontinuation
-
2002
- 2002-06-19 NO NO20022953A patent/NO20022953D0/no not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022515422A (ja) * | 2018-12-27 | 2022-02-18 | ホロスメディック | 新規の化合物およびこれを含む抗癌活性増進用薬学組成物 |
| JP7195027B2 (ja) | 2018-12-27 | 2022-12-23 | ホロスメディック | 新規の化合物およびこれを含む抗癌活性増進用薬学組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1240169A1 (en) | 2002-09-18 |
| BR0016518A (pt) | 2002-09-24 |
| NO20022953L (no) | 2002-06-19 |
| MXPA02006330A (es) | 2002-12-13 |
| CZ20022110A3 (cs) | 2002-11-13 |
| CN1413214A (zh) | 2003-04-23 |
| CO5251420A1 (es) | 2003-02-28 |
| PL355971A1 (en) | 2004-05-31 |
| IL149834A0 (en) | 2002-11-10 |
| HUP0300100A2 (en) | 2003-05-28 |
| WO2001046197A1 (en) | 2001-06-28 |
| PE20010955A1 (es) | 2001-10-11 |
| CA2393759A1 (en) | 2001-06-28 |
| NO20022953D0 (no) | 2002-06-19 |
| AU2286401A (en) | 2001-07-03 |
| KR20020062352A (ko) | 2002-07-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Dunn et al. | Stereoselective synthesis of 2, 3-diamino acids. 2, 3-Diamino-4-phenylbutanoic acid | |
| JP4994427B2 (ja) | ピクテ−スペングラー反応の変法およびその産物 | |
| JP2012508248A (ja) | ベンゾアセピン誘導体の合成方法 | |
| JP4012145B2 (ja) | ピロール−イミダゾールポリアミドの固相合成法 | |
| JPH07304770A (ja) | 新規ベンゾアゼピノン誘導体 | |
| US6872825B2 (en) | Peptide β-turn mimetic compounds and processes for making them | |
| JPH11508563A (ja) | １，４−ベンゾジアゼピン−２，５−ジオン組合わせライブラリー | |
| JP4208463B2 (ja) | キノロンカルボン酸誘導体の製造に関する中間体 | |
| JP2003518124A (ja) | ペプチドβ−ターン構造の模倣化合物及びその製法 | |
| JP4208464B2 (ja) | ナフチリジン−３−カルボン酸誘導体の製造法 | |
| JP2001502684A (ja) | アミド製造のための固相技術 | |
| US6562944B1 (en) | Amide library formation using a “by-product-free” activation/coupling sequence | |
| JP3029293B2 (ja) | ジペプチドを含む、アザビシクロナフチリジンカルボン酸の誘導体を調製するための方法 | |
| JPWO2002051797A1 (ja) | 新規な機能性ペプチド核酸モノマーとその製法 | |
| KR102589305B1 (ko) | 시타글립틴 인산염의 개선된 제조방법 | |
| AU2010243333A1 (en) | New process and new compounds | |
| JP2002540101A (ja) | プロピオン酸３−アミノ−３−アリールの合成 | |
| RU1781226C (ru) | Способ получени пироглутамилсодержащих субстратов | |
| JP3837633B2 (ja) | 新規な機能性ペプチド核酸およびその製法 | |
| JP2002513010A (ja) | スルホン化２−オキソピペラジンの固体支持合成 | |
| CN117603225A (zh) | 一种蛋白降解靶向嵌合体及其制备方法 | |
| Cwik | Pursuit of a Chiral Amino Aldehyde Intermediate in the Synthesis of ()-Obafluorin, a p-Lactone Antibiotic | |
| JP2003520845A (ja) | ナイトロジェンマスタード誘導体の調製 | |
| CA2500558A1 (en) | A process for the preparation of aza-containing bicyclic compounds and the use thereof in the preparation of cilazapril | |
| JP2002503725A (ja) | １−アミノヒダントイン化合物の固相合成 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A300 | Application deemed to be withdrawn because no request for examination was validly filed |
Free format text: JAPANESE INTERMEDIATE CODE: A300 Effective date: 20080304 |