HUP0300100A2 - Peptide betha-turn mimetic compounds and processes for making them - Google Patents
Peptide betha-turn mimetic compounds and processes for making themInfo
- Publication number
- HUP0300100A2 HUP0300100A2 HU0300100A HUP0300100A HUP0300100A2 HU P0300100 A2 HUP0300100 A2 HU P0300100A2 HU 0300100 A HU0300100 A HU 0300100A HU P0300100 A HUP0300100 A HU P0300100A HU P0300100 A2 HUP0300100 A2 HU P0300100A2
- Authority
- HU
- Hungary
- Prior art keywords
- aryl
- compounds
- betha
- peptide
- processes
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 150000001408 amides Chemical class 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004474 heteroalkylene group Chemical group 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000003949 imides Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
A találmány az általános képletű vegyületekre vonatkozik - a képletben(a) R1 hidrogénatom vagy alkilcsoport; és R2 hidrogénatom, alkil-,aril-, heterociklusos- vagy karboxicsoport és ennek észterei ésamidjai; vagy R1 és R2 összekapcsolódnak, és együtt alkilén- vagyheteroalkilén-csoportot képeznek; (b) R4 aril-, heteroaril- vagy a,b-telítetlen konjugált aril- vagy heteroaril-csoport; és (c) R5hidrogénatom, alkil-, aril- vagy heterociklusos-csoport; - és avegyületek optikai izomereire, diasztereomereire vagy enantiomereire,sóira, hidrátjaira, észtereire, amidjaira vagy imidjeire. A találmánymagába foglalja a vegyületek programkönyvtárait, és az eljárást avegyületek és a programkönyvtárak előállítására. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17282399P | 1999-12-21 | 1999-12-21 | |
| PCT/US2000/034832 WO2001046197A1 (en) | 1999-12-21 | 2000-12-20 | PEPTIDE β-TURN MIMETIC COMPOUNDS AND PROCESSES FOR MAKING THEM |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0300100A2 true HUP0300100A2 (en) | 2003-05-28 |
Family
ID=22629385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0300100A HUP0300100A2 (en) | 1999-12-21 | 2000-12-20 | Peptide betha-turn mimetic compounds and processes for making them |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1240169A1 (hu) |
| JP (1) | JP2003518124A (hu) |
| KR (1) | KR20020062352A (hu) |
| CN (1) | CN1413214A (hu) |
| AU (1) | AU2286401A (hu) |
| BR (1) | BR0016518A (hu) |
| CA (1) | CA2393759A1 (hu) |
| CO (1) | CO5251420A1 (hu) |
| CZ (1) | CZ20022110A3 (hu) |
| HU (1) | HUP0300100A2 (hu) |
| IL (1) | IL149834A0 (hu) |
| MX (1) | MXPA02006330A (hu) |
| NO (1) | NO20022953D0 (hu) |
| PE (1) | PE20010955A1 (hu) |
| PL (1) | PL355971A1 (hu) |
| WO (1) | WO2001046197A1 (hu) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020139044A1 (ko) * | 2018-12-27 | 2020-07-02 | 홀로스메딕 주식회사 | 신규한 화합물 및 이를 포함하는 항암 활성 증진용 약학 조성물 |
| BR112021012639A2 (pt) * | 2018-12-27 | 2021-09-28 | Holosmedic | Novo composto e composição farmacêutica compreendendo o mesmo para intensificar atividade anticâncer |
| BR112022007998A2 (pt) * | 2019-10-31 | 2022-07-05 | Holosmedic | Novo composto e composição farmacêutica para prevenção ou tratamento de câncer que compreende os mesmos |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6013458A (en) * | 1995-10-27 | 2000-01-11 | Molecumetics, Ltd. | Reverse-turn mimetics and methods relating thereto |
| US5929237A (en) * | 1995-10-27 | 1999-07-27 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
-
2000
- 2000-12-19 PE PE2000001366A patent/PE20010955A1/es not_active Application Discontinuation
- 2000-12-20 WO PCT/US2000/034832 patent/WO2001046197A1/en not_active Application Discontinuation
- 2000-12-20 CA CA002393759A patent/CA2393759A1/en not_active Abandoned
- 2000-12-20 CN CN00817604A patent/CN1413214A/zh active Pending
- 2000-12-20 BR BR0016518-2A patent/BR0016518A/pt not_active IP Right Cessation
- 2000-12-20 IL IL14983400A patent/IL149834A0/xx unknown
- 2000-12-20 PL PL00355971A patent/PL355971A1/xx not_active Application Discontinuation
- 2000-12-20 HU HU0300100A patent/HUP0300100A2/hu unknown
- 2000-12-20 KR KR1020027007839A patent/KR20020062352A/ko not_active Application Discontinuation
- 2000-12-20 CZ CZ20022110A patent/CZ20022110A3/cs unknown
- 2000-12-20 MX MXPA02006330A patent/MXPA02006330A/es unknown
- 2000-12-20 AU AU22864/01A patent/AU2286401A/en not_active Abandoned
- 2000-12-20 JP JP2001547107A patent/JP2003518124A/ja not_active Withdrawn
- 2000-12-20 EP EP00986673A patent/EP1240169A1/en not_active Withdrawn
- 2000-12-21 CO CO00097142A patent/CO5251420A1/es not_active Application Discontinuation
-
2002
- 2002-06-19 NO NO20022953A patent/NO20022953D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL355971A1 (en) | 2004-05-31 |
| AU2286401A (en) | 2001-07-03 |
| KR20020062352A (ko) | 2002-07-25 |
| IL149834A0 (en) | 2002-11-10 |
| CO5251420A1 (es) | 2003-02-28 |
| CN1413214A (zh) | 2003-04-23 |
| MXPA02006330A (es) | 2002-12-13 |
| CA2393759A1 (en) | 2001-06-28 |
| NO20022953L (no) | 2002-06-19 |
| BR0016518A (pt) | 2002-09-24 |
| WO2001046197A1 (en) | 2001-06-28 |
| NO20022953D0 (no) | 2002-06-19 |
| CZ20022110A3 (cs) | 2002-11-13 |
| PE20010955A1 (es) | 2001-10-11 |
| JP2003518124A (ja) | 2003-06-03 |
| EP1240169A1 (en) | 2002-09-18 |
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