ATE271551T1 - Verfahren zur herstellung von n-(1-(s)- ethoxycarbonyl-3-phenylpropyl)-l-alanin-n- carboxyanhydrid - Google Patents

Verfahren zur herstellung von n-(1-(s)- ethoxycarbonyl-3-phenylpropyl)-l-alanin-n- carboxyanhydrid

Info

Publication number
ATE271551T1
ATE271551T1 AT01124233T AT01124233T ATE271551T1 AT E271551 T1 ATE271551 T1 AT E271551T1 AT 01124233 T AT01124233 T AT 01124233T AT 01124233 T AT01124233 T AT 01124233T AT E271551 T1 ATE271551 T1 AT E271551T1
Authority
AT
Austria
Prior art keywords
phenylpropyl
alanine
sub
carboxyanhydride
ethoxycarbonyl
Prior art date
Application number
AT01124233T
Other languages
English (en)
Inventor
Chong-Ming Chen
Yu-Liang Liu
Ya-Chieh Chao
Chien-Huang Wu
Original Assignee
Everlight Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Everlight Usa Inc filed Critical Everlight Usa Inc
Application granted granted Critical
Publication of ATE271551T1 publication Critical patent/ATE271551T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44Two oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01124233T 2000-10-13 2001-10-15 Verfahren zur herstellung von n-(1-(s)- ethoxycarbonyl-3-phenylpropyl)-l-alanin-n- carboxyanhydrid ATE271551T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/689,667 US6262274B1 (en) 2000-10-13 2000-10-13 Process for preparing N-[1-(S)-ethyoxycarbonyl-3-phenylpropyl]-L-ananine N-carboxyanhydride

Publications (1)

Publication Number Publication Date
ATE271551T1 true ATE271551T1 (de) 2004-08-15

Family

ID=24769424

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01124233T ATE271551T1 (de) 2000-10-13 2001-10-15 Verfahren zur herstellung von n-(1-(s)- ethoxycarbonyl-3-phenylpropyl)-l-alanin-n- carboxyanhydrid

Country Status (8)

Country Link
US (2) US6262274B1 (de)
EP (1) EP1197490B1 (de)
JP (1) JP4154143B2 (de)
CN (1) CN1187345C (de)
AT (1) ATE271551T1 (de)
CA (1) CA2357953A1 (de)
DE (1) DE60104380T2 (de)
ES (1) ES2223701T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262274B1 (en) * 2000-10-13 2001-07-17 Everlight Usa, Inc. Process for preparing N-[1-(S)-ethyoxycarbonyl-3-phenylpropyl]-L-ananine N-carboxyanhydride
FR2815962B1 (fr) * 2000-10-30 2003-03-07 Isochem Sa Procede de preparation des n-carboxyanhydrides
JP2008545006A (ja) 2005-07-05 2008-12-11 シプラ・リミテッド Ace阻害剤の合成方法
HU229278B1 (en) * 2006-05-12 2013-10-28 Egis Gyogyszergyar Nyrt Process for the manufacturing of pharmaceutically active substances with ace - inhibitor effect and intermediates thereof and the novel intermediates
EP2044010B1 (de) 2006-05-12 2014-01-08 EGIS Gyógyszergyár Nyilvánosan Müködõ Részvénytársaság Neue pharmazeutische zwischenprodukte in der synthese von ace-inhibitoren und deren verwendung
US7659151B2 (en) * 2007-04-12 2010-02-09 Micron Technology, Inc. Flip chip with interposer, and methods of making same
CN104119424B (zh) * 2014-07-01 2018-12-18 上海天慈生物谷生物工程有限公司 (4s)-3-[(2s)-2[(1s)-1-乙氧羰基-3-苯丙基]氨基丙酰基]-1-甲基-2-氧代咪唑啉-4-羧酸的制备方法
JP6995695B2 (ja) * 2018-05-25 2022-01-17 信越化学工業株式会社 アミノ酸n-カルボキシ無水物の精製方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2644808A (en) * 1948-12-07 1953-07-07 Du Pont Nu-carboanhydrides and polymers therefrom
US4496541A (en) * 1983-01-12 1985-01-29 Usv Pharmaceutical Corporation Compounds for treating hypertension
DE3508251A1 (de) * 1985-03-08 1986-09-11 Merck Patent Gmbh, 6100 Darmstadt Dipeptide
JPS6248696A (ja) * 1985-08-27 1987-03-03 Kanegafuchi Chem Ind Co Ltd N−〔1(s)−エトキシカルボニル−3−フエニルプロピル〕−l−アラニル−l−プロリンの製造法
US6262274B1 (en) * 2000-10-13 2001-07-17 Everlight Usa, Inc. Process for preparing N-[1-(S)-ethyoxycarbonyl-3-phenylpropyl]-L-ananine N-carboxyanhydride

Also Published As

Publication number Publication date
CN1381447A (zh) 2002-11-27
DE60104380D1 (de) 2004-08-26
US6262274B1 (en) 2001-07-17
CA2357953A1 (en) 2002-04-13
DE60104380T2 (de) 2006-05-24
ES2223701T3 (es) 2005-03-01
EP1197490A1 (de) 2002-04-17
EP1197490B1 (de) 2004-07-21
JP4154143B2 (ja) 2008-09-24
US6313338B1 (en) 2001-11-06
JP2002179658A (ja) 2002-06-26
CN1187345C (zh) 2005-02-02

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