PE20010955A1 - Compuestos mimeticos de peptidos de giros beta y procesos para su fabricacion - Google Patents

Compuestos mimeticos de peptidos de giros beta y procesos para su fabricacion

Info

Publication number
PE20010955A1
PE20010955A1 PE2000001366A PE0013662000A PE20010955A1 PE 20010955 A1 PE20010955 A1 PE 20010955A1 PE 2000001366 A PE2000001366 A PE 2000001366A PE 0013662000 A PE0013662000 A PE 0013662000A PE 20010955 A1 PE20010955 A1 PE 20010955A1
Authority
PE
Peru
Prior art keywords
peptides
aryl
manufacture
processes
mimetic compounds
Prior art date
Application number
PE2000001366A
Other languages
English (en)
Inventor
Adam Golebiowski
Sean Rees Kopfenstein
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of PE20010955A1 publication Critical patent/PE20010955A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu

Abstract

SE REFIERE A COMPUESTOS MIMETICOS DE PEPTIDOS DE GIRO BETA DONDE R1 ES H, ALQUILO C1-C12, R2 ES H, ALQUILO C1-C8, ARILO, HETEROARILO DE 5-6 MIEMBROS, DOS ANILLOS FUSIONADOS DE 8-10 MIEMBROS; R4 ES ARILO, HETEROARILO, ARILO CONJUGADO, HETEROARILO O,ß-INSATURADO; R5 ES H, ALQUILO, ARILO, HETEROCICLO. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION. LOS COMPUESTO I PUEDEN SER UTILES COMO SONDAS PARA EL RECONOCIMIENTO CELULAR, INTERACCION CELULA- CELULA Y CELULA MATRIZ
PE2000001366A 1999-12-21 2000-12-19 Compuestos mimeticos de peptidos de giros beta y procesos para su fabricacion PE20010955A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17282399P 1999-12-21 1999-12-21

Publications (1)

Publication Number Publication Date
PE20010955A1 true PE20010955A1 (es) 2001-10-11

Family

ID=22629385

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000001366A PE20010955A1 (es) 1999-12-21 2000-12-19 Compuestos mimeticos de peptidos de giros beta y procesos para su fabricacion

Country Status (16)

Country Link
EP (1) EP1240169A1 (es)
JP (1) JP2003518124A (es)
KR (1) KR20020062352A (es)
CN (1) CN1413214A (es)
AU (1) AU2286401A (es)
BR (1) BR0016518A (es)
CA (1) CA2393759A1 (es)
CO (1) CO5251420A1 (es)
CZ (1) CZ20022110A3 (es)
HU (1) HUP0300100A2 (es)
IL (1) IL149834A0 (es)
MX (1) MXPA02006330A (es)
NO (1) NO20022953L (es)
PE (1) PE20010955A1 (es)
PL (1) PL355971A1 (es)
WO (1) WO2001046197A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102468480B1 (ko) * 2018-12-27 2022-11-18 홀로스메딕 주식회사 신규한 화합물 및 이를 포함하는 항암 활성 증진용 약학 조성물
WO2020139044A1 (ko) * 2018-12-27 2020-07-02 홀로스메딕 주식회사 신규한 화합물 및 이를 포함하는 항암 활성 증진용 약학 조성물
US20230019094A1 (en) * 2019-10-31 2023-01-19 Holosmedic Novel compound and pharmaceutical composition for prevention or treatment of cancer comprising same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013458A (en) * 1995-10-27 2000-01-11 Molecumetics, Ltd. Reverse-turn mimetics and methods relating thereto
US5929237A (en) * 1995-10-27 1999-07-27 Molecumetics Ltd. Reverse-turn mimetics and methods relating thereto

Also Published As

Publication number Publication date
EP1240169A1 (en) 2002-09-18
JP2003518124A (ja) 2003-06-03
CO5251420A1 (es) 2003-02-28
HUP0300100A2 (en) 2003-05-28
BR0016518A (pt) 2002-09-24
CA2393759A1 (en) 2001-06-28
CN1413214A (zh) 2003-04-23
WO2001046197A1 (en) 2001-06-28
KR20020062352A (ko) 2002-07-25
AU2286401A (en) 2001-07-03
CZ20022110A3 (cs) 2002-11-13
IL149834A0 (en) 2002-11-10
NO20022953D0 (no) 2002-06-19
MXPA02006330A (es) 2002-12-13
PL355971A1 (en) 2004-05-31
NO20022953L (no) 2002-06-19

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