CA2393759A1 - Peptide .beta.-turn mimetic compounds and processes for making them - Google Patents

Peptide .beta.-turn mimetic compounds and processes for making them Download PDF

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Publication number
CA2393759A1
CA2393759A1 CA002393759A CA2393759A CA2393759A1 CA 2393759 A1 CA2393759 A1 CA 2393759A1 CA 002393759 A CA002393759 A CA 002393759A CA 2393759 A CA2393759 A CA 2393759A CA 2393759 A1 CA2393759 A1 CA 2393759A1
Authority
CA
Canada
Prior art keywords
alkyl
heteroatoms
ring
product
heterocyclyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002393759A
Other languages
English (en)
French (fr)
Inventor
Adam Golebiowski
Sean Rees Klopfenstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2393759A1 publication Critical patent/CA2393759A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CA002393759A 1999-12-21 2000-12-20 Peptide .beta.-turn mimetic compounds and processes for making them Abandoned CA2393759A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17282399P 1999-12-21 1999-12-21
US60/172,823 1999-12-21
PCT/US2000/034832 WO2001046197A1 (en) 1999-12-21 2000-12-20 PEPTIDE β-TURN MIMETIC COMPOUNDS AND PROCESSES FOR MAKING THEM

Publications (1)

Publication Number Publication Date
CA2393759A1 true CA2393759A1 (en) 2001-06-28

Family

ID=22629385

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002393759A Abandoned CA2393759A1 (en) 1999-12-21 2000-12-20 Peptide .beta.-turn mimetic compounds and processes for making them

Country Status (16)

Country Link
EP (1) EP1240169A1 (es)
JP (1) JP2003518124A (es)
KR (1) KR20020062352A (es)
CN (1) CN1413214A (es)
AU (1) AU2286401A (es)
BR (1) BR0016518A (es)
CA (1) CA2393759A1 (es)
CO (1) CO5251420A1 (es)
CZ (1) CZ20022110A3 (es)
HU (1) HUP0300100A2 (es)
IL (1) IL149834A0 (es)
MX (1) MXPA02006330A (es)
NO (1) NO20022953L (es)
PE (1) PE20010955A1 (es)
PL (1) PL355971A1 (es)
WO (1) WO2001046197A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019416623B2 (en) * 2018-12-27 2022-12-08 Holosmedic Novel compound and pharmaceutical composition comprising same for enhancing anticancer activity
WO2020139044A1 (ko) * 2018-12-27 2020-07-02 홀로스메딕 주식회사 신규한 화합물 및 이를 포함하는 항암 활성 증진용 약학 조성물
KR102622152B1 (ko) * 2019-10-31 2024-01-08 홀로스메딕 주식회사 신규한 화합물 및 이를 포함하는 암 예방 또는 치료용 약학 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013458A (en) * 1995-10-27 2000-01-11 Molecumetics, Ltd. Reverse-turn mimetics and methods relating thereto
US5929237A (en) * 1995-10-27 1999-07-27 Molecumetics Ltd. Reverse-turn mimetics and methods relating thereto

Also Published As

Publication number Publication date
AU2286401A (en) 2001-07-03
PL355971A1 (en) 2004-05-31
HUP0300100A2 (en) 2003-05-28
IL149834A0 (en) 2002-11-10
KR20020062352A (ko) 2002-07-25
BR0016518A (pt) 2002-09-24
PE20010955A1 (es) 2001-10-11
JP2003518124A (ja) 2003-06-03
NO20022953D0 (no) 2002-06-19
CN1413214A (zh) 2003-04-23
WO2001046197A1 (en) 2001-06-28
MXPA02006330A (es) 2002-12-13
CZ20022110A3 (cs) 2002-11-13
EP1240169A1 (en) 2002-09-18
NO20022953L (no) 2002-06-19
CO5251420A1 (es) 2003-02-28

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued