|
JP2001026506A
(ja)
*
|
1999-04-28 |
2001-01-30 |
Takeda Chem Ind Ltd |
スルホンアミド誘導体
|
|
US6586617B1
(en)
*
|
1999-04-28 |
2003-07-01 |
Sumitomo Chemical Takeda Agro Company, Limited |
Sulfonamide derivatives
|
|
US6503949B1
(en)
*
|
1999-05-17 |
2003-01-07 |
Noro Nordisk A/S |
Glucagon antagonists/inverse agonists
|
|
CA2423933A1
(en)
|
2000-10-17 |
2002-04-25 |
Applied Research Systems Ars Holding N.V. |
Pharmaceutically active sulfanilide derivatives
|
|
US6657070B2
(en)
|
2000-12-13 |
2003-12-02 |
Wyeth |
Production of chirally pure α-amino acids and N-sulfonyl α-amino acids
|
|
NZ538100A
(en)
|
2000-12-13 |
2006-07-28 |
Arqule Inc |
Heterocyclic sulfonamide inhibitors of beta amyloid production
|
|
GB0108591D0
(en)
|
2001-04-05 |
2001-05-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB0108592D0
(en)
|
2001-04-05 |
2001-05-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP1435955A2
(en)
*
|
2001-05-05 |
2004-07-14 |
SmithKline Beecham P.L.C. |
N-aroyl cyclic amine derivatives as orexin receptor antagonists
|
|
GB0115862D0
(en)
*
|
2001-06-28 |
2001-08-22 |
Smithkline Beecham Plc |
Compounds
|
|
MXPA04001016A
(es)
*
|
2001-08-03 |
2004-05-27 |
Schering Corp |
Derivados de sulfonamida como inhibidores de la gamma secretasa.
|
|
ATE515495T1
(de)
*
|
2001-08-03 |
2011-07-15 |
Schering Corp |
Gamma sekretase inhibitoren
|
|
GB0120347D0
(en)
|
2001-08-21 |
2001-10-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GEP20063920B
(en)
*
|
2001-12-20 |
2006-09-11 |
Bristol Myers Squibb Co |
Alpha-(n-sulphonamido) acetamide derivatives as beta-amyloid inhibitors
|
|
PE20030701A1
(es)
|
2001-12-20 |
2003-08-21 |
Schering Corp |
Compuestos para el tratamiento de trastornos inflamatorios
|
|
RU2304140C2
(ru)
|
2001-12-27 |
2007-08-10 |
Дайити Фармасьютикал Ко., Лтд. |
ИНГИБИТОРЫ ПРОДУЦИРОВАНИЯ / СЕКРЕЦИИ β-АМИЛОИДНОГО БЕЛКА
|
|
DE10201392A1
(de)
*
|
2002-01-16 |
2003-07-31 |
Bayer Ag |
Phenylsulfoxide und-sulfone
|
|
KR20050010882A
(ko)
*
|
2002-06-11 |
2005-01-28 |
와이어쓰 |
베타 아밀로이드 생산의 치환 페닐술폰아미드 저해제
|
|
US6989399B2
(en)
|
2002-08-01 |
2006-01-24 |
Bristol-Myers Squibb Company |
Antiamyloid phenylsulfonamides: N-alkanol derivatives
|
|
GB0223038D0
(en)
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
GB0223039D0
(en)
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
GB0223040D0
(en)
*
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
WO2004033418A2
(en)
|
2002-10-11 |
2004-04-22 |
Actelion Pharmaceuticals Ltd. |
Sulfonylamino-acetic derivatives and their use as orexin receptor antagonists
|
|
US7521481B2
(en)
|
2003-02-27 |
2009-04-21 |
Mclaurin Joanne |
Methods of preventing, treating and diagnosing disorders of protein aggregation
|
|
WO2004080952A1
(de)
*
|
2003-03-10 |
2004-09-23 |
Bayer Healthcare Ag |
Phenylsulfonamid-derivate zur behandlung der alzheimerschen krankheit
|
|
AU2004230844B2
(en)
|
2003-03-31 |
2010-12-09 |
Wyeth |
Fluoro-and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof
|
|
EP1633354B1
(en)
*
|
2003-04-14 |
2008-01-23 |
The Institutes for Pharmaceutical Discovery, LLC |
N-(((((1,3-thiazol-2-yl)amino)carbonyl)phenyl)sulfonyl)phenylalanine derivatives and related compounds for the treatment of diabetes
|
|
WO2004101562A2
(en)
|
2003-05-13 |
2004-11-25 |
Schering Corporation |
Bridged n-arylsulfonylpiperidines as gamma-secretase inhibitors
|
|
EP1644346A1
(en)
|
2003-05-16 |
2006-04-12 |
MERCK SHARP & DOHME LTD. |
Cyclic sulfonamides for inhibition of gamma-secretase
|
|
CA2529256A1
(en)
*
|
2003-06-23 |
2004-12-29 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
RU2336270C2
(ru)
|
2003-06-30 |
2008-10-20 |
Дайити Фармасьютикал Ко., Лтд. |
Гетероциклические метилсульфоновые производные
|
|
US7598250B2
(en)
|
2003-08-08 |
2009-10-06 |
Schering Corporation |
Cyclic amine BACE-1 inhibitors having a heterocyclic substituent
|
|
ATE424383T1
(de)
|
2003-08-08 |
2009-03-15 |
Schering Corp |
Cyclische amine mit benzamidsubstituent als bace- 1-inhibitoren
|
|
GB0323258D0
(en)
|
2003-10-04 |
2003-11-05 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
JP2007512242A
(ja)
*
|
2003-10-29 |
2007-05-17 |
イーラン ファーマスーティカルズ、インコーポレイテッド |
Ｎ−置換ベンゼンスルホンアミド
|
|
CA2552558A1
(en)
|
2004-01-16 |
2005-08-11 |
Wyeth |
Heterocyclic sulfonamide inhibitors of beta amyloid production containing an azole
|
|
EP1723102A2
(en)
|
2004-03-11 |
2006-11-22 |
Elan Pharmaceuticals, Inc. |
N-substituted benzene sulfonamides
|
|
JP2007531753A
(ja)
*
|
2004-03-31 |
2007-11-08 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
非イミダゾール系複素環式化合物
|
|
CA2566094A1
(en)
|
2004-05-26 |
2005-12-08 |
Eisai R & D Management Co., Ltd. |
Cinnamide compound
|
|
MX2007000040A
(es)
|
2004-06-30 |
2007-03-07 |
Schering Corp |
N-arilsulfonilaminas heterociclicas sustituidas como inhibidores de gamma-secretasas.
|
|
DE602005025363D1
(de)
|
2004-07-22 |
2011-01-27 |
Schering Corp |
Substituierte amide als inhibitoren der beta-sekretase
|
|
AU2005297966B2
(en)
|
2004-10-26 |
2010-12-23 |
Eisai R & D Management Co., Ltd. |
Amorphous object of cinnamide compound
|
|
JP2008518926A
(ja)
*
|
2004-10-28 |
2008-06-05 |
ジ インスティチューツ フォー ファーマシューティカル ディスカバリー、エルエルシー |
置換フェニルアルカン酸
|
|
EP1838701A1
(en)
|
2005-01-18 |
2007-10-03 |
Elan Pharmaceuticals Inc. |
N-substituted heterocyclic sulfonamides
|
|
AU2006209079A1
(en)
|
2005-01-27 |
2006-08-03 |
Alma Mater Studiorum-Universita' Di Bologna |
Organic compounds useful for the treatment of Alzheimer's disease, their use and method of preparation
|
|
ES2413705T3
(es)
*
|
2005-04-08 |
2013-07-17 |
Daiichi Sankyo Company, Limited |
Derivado de piridilmetilsulfona
|
|
BRPI0618814A2
(pt)
|
2005-11-24 |
2014-04-29 |
Eisai R&D Man Co Ltd |
Composto ou um sal farmacologicamente aceitável do mesmo, e, agente farmacêutico
|
|
TWI370130B
(en)
|
2005-11-24 |
2012-08-11 |
Eisai R&D Man Co Ltd |
Two cyclic cinnamide compound
|
|
EP1976843B1
(en)
|
2006-01-20 |
2013-09-04 |
Merck Sharp & Dohme Corp. |
Carbocyclic and heterocyclic arylsulfones as gamma secretase inhibitors
|
|
CA2641555A1
(en)
*
|
2006-02-06 |
2007-08-16 |
Elan Pharmaceuticals, Inc. |
Preferential inhibition of presenilin-1
|
|
US9567396B2
(en)
|
2006-03-07 |
2017-02-14 |
Evonik Degussa Gmbh |
Notch inhibition in the prevention of vein graft failure
|
|
US8133857B2
(en)
|
2006-03-07 |
2012-03-13 |
The Brigham and Women's FHospital, Inc. |
NOTCH inhibition in the treatment of atherosclerosis
|
|
WO2011053822A2
(en)
|
2009-11-01 |
2011-05-05 |
The Brigham And Women's Hospital, Inc. |
Notch inhibition in the treatment and prevention of obesity and metabolic syndrome
|
|
TWI378091B
(en)
|
2006-03-09 |
2012-12-01 |
Eisai R&D Man Co Ltd |
Multi-cyclic cinnamide derivatives
|
|
US8003654B2
(en)
|
2006-04-11 |
2011-08-23 |
Actelion Pharmaceuticals Ltd. |
N-glycinsulfonamide derivatives and uses as orexin receptor antagonists
|
|
CA2653940C
(en)
|
2006-05-30 |
2015-07-14 |
Janssen Pharmaceutica N.V. |
Substituted pyridyl amide compounds as modulators of the histamine h3 receptor
|
|
US7737141B2
(en)
|
2006-07-28 |
2010-06-15 |
Eisai R&D Management Co., Ltd. |
Prodrug of cinnamide compound
|
|
TW200817319A
(en)
|
2006-08-10 |
2008-04-16 |
Astellas Pharma Inc |
Sulfonamide compound or salt thereof
|
|
US20110053995A1
(en)
*
|
2006-11-16 |
2011-03-03 |
The Regents Of The University Of California |
Benzenesulfonanilide compound inhibitors of urea transporters
|
|
AU2008215948A1
(en)
|
2007-02-12 |
2008-08-21 |
Merck & Co., Inc. |
Piperazine derivatives for treatment of AD and related conditions
|
|
EP2435416B1
(en)
|
2007-07-05 |
2016-03-30 |
Merck Sharp & Dohme Corp. |
Tetrahydropyranochromene gamma secretase inhibitors
|
|
EP2178882B1
(en)
|
2007-07-17 |
2013-04-17 |
Merck Sharp & Dohme Corp. |
Benzenesulfonyl-chromane, thiochromane, tetrahydronaphthalene and related gamma secretase inhibitors
|
|
US7935815B2
(en)
|
2007-08-31 |
2011-05-03 |
Eisai R&D Management Co., Ltd. |
Imidazoyl pyridine compounds and salts thereof
|
|
CA2694401C
(en)
|
2007-08-31 |
2012-12-04 |
Eisai R&D Management Co., Ltd. |
Polycyclic compound
|
|
TW200920362A
(en)
|
2007-09-11 |
2009-05-16 |
Daiichi Sankyo Co Ltd |
Alkylsulfone derivatives
|
|
US8084477B2
(en)
|
2007-10-31 |
2011-12-27 |
Bristol-Myers Squibb Company |
Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production
|
|
US8093276B2
(en)
|
2007-10-31 |
2012-01-10 |
Bristol-Myers Squibb Company |
Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production
|
|
EA018582B1
(ru)
|
2007-11-20 |
2013-09-30 |
Янссен Фармацевтика Н.В. |
Соединения циклоалкилокси- и гетероциклоалкилоксипиридина как модуляторы гистаминового рецептора н
|
|
PT2222636E
(pt)
|
2007-12-21 |
2013-07-16 |
Ligand Pharm Inc |
Moduladores seletivos de recetores de andrógeno (sarms) e suas utilizações
|
|
WO2009120783A1
(en)
*
|
2008-03-25 |
2009-10-01 |
The Johns Hopkins University |
High affinity inhibitors of hepatitis c virus ns3/4a protease
|
|
US8461389B2
(en)
|
2008-04-18 |
2013-06-11 |
University College Dublin, National University Of Ireland, Dublin |
Psycho-pharmaceuticals
|
|
JP2011523633A
(ja)
*
|
2008-05-08 |
2011-08-18 |
ブリストル−マイヤーズ スクイブ カンパニー |
２−アリールグリシンアミド誘導体
|
|
GB0812969D0
(en)
|
2008-07-15 |
2008-08-20 |
Sentinel Oncology Ltd |
Pharmaceutical compounds
|
|
TW201020247A
(en)
*
|
2008-11-06 |
2010-06-01 |
Gruenenthal Gmbh |
Substituierte disulfonamide
|
|
US8044077B2
(en)
|
2009-03-19 |
2011-10-25 |
Bristol-Myers Squibb Company |
Alpha-(N-sulfonamido)acetamide compounds incorporating deuterium as inhibitors of beta amyloid peptide production
|
|
US7977362B2
(en)
|
2009-03-20 |
2011-07-12 |
Bristol-Myers Squibb Company |
Alpha-(N-benzenesulfonamido)cycloalkyl derivatives
|
|
US8252821B2
(en)
|
2009-04-14 |
2012-08-28 |
Bristol-Myers Squibb Company |
Bioavailable capsule compositions of amorphous alpha-(N-sulfonamido)acetamide compound
|
|
US8399465B2
(en)
|
2009-05-14 |
2013-03-19 |
Janssen Pharmaceutica Nv |
Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene A4 hydrolase
|
|
CN103193691B
(zh)
*
|
2012-01-06 |
2017-08-25 |
中国科学院上海药物研究所 |
磺胺类化合物、药物组合物及其制法和应用
|
|
EP2819671A4
(en)
*
|
2012-02-29 |
2016-05-11 |
Baruch S Blumberg Inst |
INHIBITORS OF HEPATITIS B VIRUS WITH COVALENT CLOSED CIRCULAR DNA PREPARATION AND ITS USE METHOD
|
|
US9688715B2
(en)
|
2012-06-22 |
2017-06-27 |
Temple University—Of the Commonwealth System of Higher Education |
Synthetic pGpG analogs, methods of preparation and methods of use
|
|
BR112015006737A2
(pt)
*
|
2012-09-27 |
2017-07-04 |
Hoffmann La Roche |
compostos de sulfonamida substituídos
|
|
EP2981522A4
(en)
|
2013-04-05 |
2016-08-31 |
Salk Inst For Biological Studi |
PPAR AGONISTS
|
|
US10441567B2
(en)
|
2014-01-17 |
2019-10-15 |
Ligand Pharmaceuticals Incorporated |
Methods and compositions for modulating hormone levels
|
|
EP2932966A1
(en)
|
2014-04-16 |
2015-10-21 |
Novartis AG |
Gamma secretase inhibitors for treating respiratory diseases
|
|
CN104151277A
(zh)
*
|
2014-06-30 |
2014-11-19 |
北京万全德众医药生物技术有限公司 |
盐酸决奈达隆一种氧化杂质的制备方法
|
|
WO2016057322A1
(en)
|
2014-10-08 |
2016-04-14 |
Salk Institute For Biological Studies |
Ppar agonists and methods of use thereof
|
|
WO2016090317A1
(en)
*
|
2014-12-05 |
2016-06-09 |
Aquinnah Pharmaceuticals, Inc. |
Sulfonamide derivatives, compositions and methods of use in the treatment of neurodegenerative diseases
|
|
CN106466313A
(zh)
*
|
2015-08-18 |
2017-03-01 |
中国科学院上海药物研究所 |
一类磺酰胺基取代的酰胺类衍生物在制备用于治疗阿尔茨海默病的药物中的用途
|
|
UA122237C2
(uk)
|
2015-10-07 |
2020-10-12 |
Мітобрідж, Інк. |
Агоністи ppar, сполуки, фармацевтичні композиції та способи їх застосування
|
|
MX380531B
(es)
|
2016-04-13 |
2025-03-12 |
Mitobridge Inc |
Agonistas del receptor activado por proliferador de peroxisoma (ppar), compuestos, composiciones farmacéuticas y métodos para usar los mismos.
|
|
TWI754702B
(zh)
*
|
2016-12-28 |
2022-02-11 |
德商Ｕｃｂ製藥有限公司 |
（氮雜）吲哚－和苯並呋喃－３－磺醯胺類
|
|
WO2019139869A1
(en)
|
2018-01-10 |
2019-07-18 |
Cura Therapeutics Llc |
Pharmaceutical compositions comprising phenylsulfonamides, and their therapeutic applications
|
|
WO2020016377A1
(en)
|
2018-07-19 |
2020-01-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combination for treating cancer
|
|
MX2021012690A
(es)
|
2019-04-19 |
2022-01-31 |
Ligand Pharm Inc |
Formas cristalinas y metodos para producir formas cristalinas de un compuesto.
|
|
EP3996813A1
(en)
*
|
2019-07-11 |
2022-05-18 |
Cura Therapeutics, LLC |
Phenyl compounds and pharmaceutical compositions thereof, and their therapeutic applications
|
|
CN112457687B
(zh)
*
|
2019-09-06 |
2022-10-25 |
台湾永光化学工业股份有限公司 |
新颖反应性染料
|
|
WO2022101481A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|