DK1341779T3 - Heterocyklisk sulfonamid-inhibitorer af beta-amyloidproduktion - Google Patents

Heterocyklisk sulfonamid-inhibitorer af beta-amyloidproduktion

Info

Publication number
DK1341779T3
DK1341779T3 DK01993277T DK01993277T DK1341779T3 DK 1341779 T3 DK1341779 T3 DK 1341779T3 DK 01993277 T DK01993277 T DK 01993277T DK 01993277 T DK01993277 T DK 01993277T DK 1341779 T3 DK1341779 T3 DK 1341779T3
Authority
DK
Denmark
Prior art keywords
beta
amyloid production
heterocyclic sulfonamide
sulfonamide inhibitors
inhibitors
Prior art date
Application number
DK01993277T
Other languages
English (en)
Inventor
Anthony Frank Kreft
Derek Cecil Cole
Kevin Roger Woller
Joseph Raymond Stock
Dennis Michael Kurbrak
Kristina Martha Kutterer
David Scott Casebier
William Jay Moore
George Diamanitis
Original Assignee
Wyeth Corp
Arqule Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22966854&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1341779(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp, Arqule Inc filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK1341779T3 publication Critical patent/DK1341779T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK01993277T 2000-12-13 2001-12-11 Heterocyklisk sulfonamid-inhibitorer af beta-amyloidproduktion DK1341779T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25510500P 2000-12-13 2000-12-13

Publications (1)

Publication Number Publication Date
DK1341779T3 true DK1341779T3 (da) 2006-10-30

Family

ID=22966854

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01993277T DK1341779T3 (da) 2000-12-13 2001-12-11 Heterocyklisk sulfonamid-inhibitorer af beta-amyloidproduktion

Country Status (28)

Country Link
US (5) US6610734B2 (da)
EP (1) EP1341779B1 (da)
JP (2) JP2004517892A (da)
KR (1) KR100869061B1 (da)
CN (2) CN1263750C (da)
AR (1) AR035516A1 (da)
AT (1) ATE330950T1 (da)
AU (1) AU2002245123B2 (da)
BR (1) BR0116063A (da)
CA (1) CA2436526C (da)
CY (1) CY1105441T1 (da)
DE (1) DE60121032T2 (da)
DK (1) DK1341779T3 (da)
EA (1) EA009035B1 (da)
ES (1) ES2267853T3 (da)
HK (1) HK1059619A1 (da)
HU (1) HUP0303857A3 (da)
IL (3) IL156268A0 (da)
MX (1) MXPA03005255A (da)
NO (1) NO328885B1 (da)
NZ (2) NZ538100A (da)
PL (1) PL365950A1 (da)
PT (1) PT1341779E (da)
SG (1) SG128491A1 (da)
SI (1) SI1341779T1 (da)
TW (1) TWI235155B (da)
WO (1) WO2002057252A2 (da)
ZA (1) ZA200304135B (da)

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TW200800959A (en) * 2005-06-10 2008-01-01 Wyeth Corp Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor
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US7687666B2 (en) * 2006-02-17 2010-03-30 Wyeth Methods for preparing sulfonamide substituted alcohols and intermediates thereof
TW200732295A (en) * 2006-02-17 2007-09-01 Wyeth Corp Selective N-sulfonylation of 2-amino trifluoroalkyl substituted alcohols
US7476762B2 (en) * 2006-04-21 2009-01-13 Wyeth Methods for preparing sulfonamide compounds
CN101472877A (zh) * 2006-04-21 2009-07-01 惠氏公司 制备手性纯氨基醇中间体、其衍生物及其用途
US7550629B2 (en) * 2006-04-21 2009-06-23 Wyeth Trifluoromethyl-containing phenylsulfonamide beta amyloid inhibitors
TW200811144A (en) * 2006-06-09 2008-03-01 Wyeth Corp Crystalline forms of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline
TW200808740A (en) * 2006-06-09 2008-02-16 Wyeth Corp Succinate salts of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline and crystalline forms thereof
TW200808741A (en) * 2006-06-09 2008-02-16 Wyeth Corp 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline hydrochloric acid salts
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Also Published As

Publication number Publication date
US20020183361A1 (en) 2002-12-05
SG128491A1 (en) 2007-01-30
HUP0303857A2 (hu) 2004-03-29
JP2004517892A (ja) 2004-06-17
US20050196813A1 (en) 2005-09-08
US20100022594A1 (en) 2010-01-28
AR035516A1 (es) 2004-06-02
CN1263750C (zh) 2006-07-12
PL365950A1 (en) 2005-01-24
NZ538100A (en) 2006-07-28
IL156268A0 (en) 2004-01-04
PT1341779E (pt) 2006-10-31
ZA200304135B (en) 2004-09-03
WO2002057252A3 (en) 2002-12-12
HK1059619A1 (en) 2004-07-09
EP1341779A2 (en) 2003-09-10
NZ526213A (en) 2005-05-27
ES2267853T3 (es) 2007-03-16
AU2002245123B2 (en) 2007-05-24
US7691884B2 (en) 2010-04-06
CY1105441T1 (el) 2010-07-28
CA2436526A1 (en) 2002-07-25
US6878742B2 (en) 2005-04-12
KR20040018318A (ko) 2004-03-03
DE60121032D1 (de) 2006-08-03
CN1800176A (zh) 2006-07-12
JP2010265280A (ja) 2010-11-25
IL188853A0 (en) 2011-08-01
HUP0303857A3 (en) 2007-07-30
KR100869061B1 (ko) 2008-11-17
BR0116063A (pt) 2004-08-03
TWI235155B (en) 2005-07-01
WO2002057252A2 (en) 2002-07-25
EA200300674A1 (ru) 2004-06-24
IL156268A (en) 2008-04-13
NO328885B1 (no) 2010-06-07
US20030229127A1 (en) 2003-12-11
US20110034513A1 (en) 2011-02-10
US7842718B2 (en) 2010-11-30
EA009035B1 (ru) 2007-10-26
ATE330950T1 (de) 2006-07-15
EP1341779B1 (en) 2006-06-21
SI1341779T1 (sl) 2006-12-31
NO20032645D0 (no) 2003-06-11
MXPA03005255A (es) 2004-10-14
DE60121032T2 (de) 2007-01-11
US6610734B2 (en) 2003-08-26
CA2436526C (en) 2010-10-19
NO20032645L (no) 2003-08-05
CN1503790A (zh) 2004-06-09

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