PT1341779E - Sulfonamidas heterociclicas inibidoras da producao de beta-amiloide - Google Patents

Sulfonamidas heterociclicas inibidoras da producao de beta-amiloide

Info

Publication number
PT1341779E
PT1341779E PT01993277T PT01993277T PT1341779E PT 1341779 E PT1341779 E PT 1341779E PT 01993277 T PT01993277 T PT 01993277T PT 01993277 T PT01993277 T PT 01993277T PT 1341779 E PT1341779 E PT 1341779E
Authority
PT
Portugal
Prior art keywords
inhibitors
beta
amyloid production
heterocyclic sulfonamides
sulfonamides
Prior art date
Application number
PT01993277T
Other languages
English (en)
Inventor
Kreft Anthony Frank
Derek Cecil Cole
Woller Kevin Roger
Stock Joseph Raymond
Kurbrak Dennis Michael
Kutterer Kristina Martha
Moore William Jay
Casebier David Scott
Diamanitis George
Original Assignee
Wyeth Corp
Arqule Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22966854&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1341779(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp, Arqule Inc filed Critical Wyeth Corp
Publication of PT1341779E publication Critical patent/PT1341779E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT01993277T 2000-12-13 2001-12-11 Sulfonamidas heterociclicas inibidoras da producao de beta-amiloide PT1341779E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25510500P 2000-12-13 2000-12-13

Publications (1)

Publication Number Publication Date
PT1341779E true PT1341779E (pt) 2006-10-31

Family

ID=22966854

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01993277T PT1341779E (pt) 2000-12-13 2001-12-11 Sulfonamidas heterociclicas inibidoras da producao de beta-amiloide

Country Status (28)

Country Link
US (5) US6610734B2 (pt)
EP (1) EP1341779B1 (pt)
JP (2) JP2004517892A (pt)
KR (1) KR100869061B1 (pt)
CN (2) CN1800176A (pt)
AR (1) AR035516A1 (pt)
AT (1) ATE330950T1 (pt)
AU (1) AU2002245123B2 (pt)
BR (1) BR0116063A (pt)
CA (1) CA2436526C (pt)
CY (1) CY1105441T1 (pt)
DE (1) DE60121032T2 (pt)
DK (1) DK1341779T3 (pt)
EA (1) EA009035B1 (pt)
ES (1) ES2267853T3 (pt)
HK (1) HK1059619A1 (pt)
HU (1) HUP0303857A3 (pt)
IL (3) IL156268A0 (pt)
MX (1) MXPA03005255A (pt)
NO (1) NO328885B1 (pt)
NZ (2) NZ526213A (pt)
PL (1) PL365950A1 (pt)
PT (1) PT1341779E (pt)
SG (1) SG128491A1 (pt)
SI (1) SI1341779T1 (pt)
TW (1) TWI235155B (pt)
WO (1) WO2002057252A2 (pt)
ZA (1) ZA200304135B (pt)

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CA2649396A1 (en) * 2006-04-21 2007-11-08 Wyeth Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof
US7476762B2 (en) * 2006-04-21 2009-01-13 Wyeth Methods for preparing sulfonamide compounds
US7550629B2 (en) * 2006-04-21 2009-06-23 Wyeth Trifluoromethyl-containing phenylsulfonamide beta amyloid inhibitors
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TW200808740A (en) * 2006-06-09 2008-02-16 Wyeth Corp Succinate salts of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline and crystalline forms thereof
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US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
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CN104370769B (zh) * 2013-08-14 2017-05-31 重庆博腾制药科技股份有限公司 一种制备羟基金刚烷甘氨酸衍生物的方法
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Also Published As

Publication number Publication date
EP1341779A2 (en) 2003-09-10
ES2267853T3 (es) 2007-03-16
CN1503790A (zh) 2004-06-09
NO20032645L (no) 2003-08-05
EP1341779B1 (en) 2006-06-21
CY1105441T1 (el) 2010-07-28
DE60121032T2 (de) 2007-01-11
NZ526213A (en) 2005-05-27
TWI235155B (en) 2005-07-01
ATE330950T1 (de) 2006-07-15
JP2004517892A (ja) 2004-06-17
NO328885B1 (no) 2010-06-07
NZ538100A (en) 2006-07-28
DK1341779T3 (da) 2006-10-30
JP2010265280A (ja) 2010-11-25
KR100869061B1 (ko) 2008-11-17
NO20032645D0 (no) 2003-06-11
US20050196813A1 (en) 2005-09-08
US20100022594A1 (en) 2010-01-28
PL365950A1 (en) 2005-01-24
HUP0303857A2 (hu) 2004-03-29
ZA200304135B (en) 2004-09-03
EA009035B1 (ru) 2007-10-26
SI1341779T1 (sl) 2006-12-31
CA2436526A1 (en) 2002-07-25
AR035516A1 (es) 2004-06-02
IL156268A0 (en) 2004-01-04
US20110034513A1 (en) 2011-02-10
HK1059619A1 (en) 2004-07-09
IL188853A0 (en) 2011-08-01
IL156268A (en) 2008-04-13
CN1263750C (zh) 2006-07-12
HUP0303857A3 (en) 2007-07-30
KR20040018318A (ko) 2004-03-03
WO2002057252A2 (en) 2002-07-25
MXPA03005255A (es) 2004-10-14
US6610734B2 (en) 2003-08-26
US7842718B2 (en) 2010-11-30
SG128491A1 (en) 2007-01-30
US6878742B2 (en) 2005-04-12
CA2436526C (en) 2010-10-19
US20020183361A1 (en) 2002-12-05
EA200300674A1 (ru) 2004-06-24
CN1800176A (zh) 2006-07-12
BR0116063A (pt) 2004-08-03
US7691884B2 (en) 2010-04-06
WO2002057252A3 (en) 2002-12-12
AU2002245123B2 (en) 2007-05-24
US20030229127A1 (en) 2003-12-11
DE60121032D1 (de) 2006-08-03

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