JP2002161074A5 - - Google Patents
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- JP2002161074A5 JP2002161074A5 JP2001255372A JP2001255372A JP2002161074A5 JP 2002161074 A5 JP2002161074 A5 JP 2002161074A5 JP 2001255372 A JP2001255372 A JP 2001255372A JP 2001255372 A JP2001255372 A JP 2001255372A JP 2002161074 A5 JP2002161074 A5 JP 2002161074A5
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- JP
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- Prior art keywords
- neuraminidase
- compound
- label
- sample
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39524595A | 1995-02-27 | 1995-02-27 | |
| US08/395,245 | 1995-02-27 | ||
| US08/476,946 | 1995-06-06 | ||
| US08/476,946 US5866601A (en) | 1995-02-27 | 1995-06-06 | Carbocyclic compounds |
| US58056795A | 1995-12-29 | 1995-12-29 | |
| US08/580,567 | 1995-12-29 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52644296A Division JP3300365B2 (ja) | 1995-02-27 | 1996-02-26 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005207906A Division JP2006036770A (ja) | 1995-02-27 | 2005-07-15 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
| JP2008082197A Division JP2008273948A (ja) | 1995-02-27 | 2008-03-26 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002161074A JP2002161074A (ja) | 2002-06-04 |
| JP2002161074A5 true JP2002161074A5 (https=) | 2005-10-27 |
| JP4234917B2 JP4234917B2 (ja) | 2009-03-04 |
Family
ID=27410155
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52644296A Expired - Lifetime JP3300365B2 (ja) | 1995-02-27 | 1996-02-26 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
| JP2001255372A Expired - Lifetime JP4234917B2 (ja) | 1995-02-27 | 2001-08-24 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
| JP2005207906A Withdrawn JP2006036770A (ja) | 1995-02-27 | 2005-07-15 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52644296A Expired - Lifetime JP3300365B2 (ja) | 1995-02-27 | 1996-02-26 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005207906A Withdrawn JP2006036770A (ja) | 1995-02-27 | 2005-07-15 | ウイルスまたは細菌ノイラミニダーゼの新規な選択的インヒビター |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US5952375A (https=) |
| EP (1) | EP0759917B1 (https=) |
| JP (3) | JP3300365B2 (https=) |
| KR (1) | KR100447096B1 (https=) |
| CN (2) | CN1185223C (https=) |
| AT (2) | ATE191711T1 (https=) |
| AU (1) | AU720933B2 (https=) |
| BR (2) | BR9607098B8 (https=) |
| CZ (1) | CZ297945B6 (https=) |
| DE (4) | DE69607704T2 (https=) |
| DK (1) | DK0759917T3 (https=) |
| ES (2) | ES2249863T3 (https=) |
| GR (1) | GR3033914T3 (https=) |
| HU (1) | HU228450B1 (https=) |
| LU (1) | LU90991I2 (https=) |
| MX (1) | MX9706496A (https=) |
| NL (1) | NL300105I2 (https=) |
| NO (1) | NO318455B1 (https=) |
| NZ (1) | NZ306625A (https=) |
| PL (1) | PL194173B1 (https=) |
| PT (1) | PT759917E (https=) |
| RU (1) | RU2181357C2 (https=) |
| SG (1) | SG45864A1 (https=) |
| SI (1) | SI9620042A (https=) |
| UA (1) | UA56128C2 (https=) |
| WO (1) | WO1996026933A1 (https=) |
Families Citing this family (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9607098B8 (pt) | 1995-02-27 | 2014-11-18 | Gilead Sciences Inc | Composto e composição farmacêutica. |
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| US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
| US6093816A (en) | 1996-06-27 | 2000-07-25 | Isis Pharmaceuticals, Inc. | Cationic lipids |
| US5859284A (en) | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| US6518438B2 (en) | 1996-08-23 | 2003-02-11 | Gilead Sciences, Inc. | Preparation of cyclohexene carboxylate derivatives |
| DE69711395T2 (de) * | 1996-08-23 | 2002-11-07 | Gilead Sciences, Inc. | Verfahren zur herstellung von cyclohexen-carboxylatderivate |
| US5994377A (en) * | 1996-10-21 | 1999-11-30 | Gilead Sciences, Inc. | Piperidine compounds |
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| NZ335368A (en) * | 1996-11-14 | 2001-08-31 | Biota Scient Management | Macromolecular compound with one or more neuraminidase binders, binds to the active site of influenza virus neuraminidase |
| AU8673598A (en) * | 1997-08-01 | 1999-02-22 | University Of Florida | Neuraminidase inhibitors |
| US5886213A (en) * | 1997-08-22 | 1999-03-23 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| NZ502988A (en) * | 1997-09-17 | 2002-08-28 | Gilead Sciences Inc | 5-Acetamido-4-amino-2-propionyloxy-6-isopropoxy-1-cyclohexene useful for treating influenza |
| US20040053999A1 (en) * | 1997-09-17 | 2004-03-18 | Bischofberger Norbert W. | Novel compounds and methods for synthesis and therapy |
| TW477783B (en) * | 1997-12-12 | 2002-03-01 | Gilead Sciences Inc | Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same |
| CA2315262C (en) * | 1997-12-17 | 2009-11-10 | Biocryst Pharmaceuticals, Inc. | Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors |
| EP1315698A1 (en) * | 1998-04-23 | 2003-06-04 | Abbott Laboratories | Pyrrolidines as inhibitors of neuraminidases |
| US6455571B1 (en) | 1998-04-23 | 2002-09-24 | Abbott Laboratories | Inhibitors of neuraminidases |
| US6518305B1 (en) | 1998-04-23 | 2003-02-11 | Abbott Laboratories | Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases |
| DE69900483T2 (de) * | 1998-05-13 | 2002-06-27 | F. Hoffmann-La Roche Ag, Basel | Verfahren zur Herstellung von Shikiminsäure und deren Derivate |
| WO2000029385A1 (en) * | 1998-11-13 | 2000-05-25 | Gilead Sciences, Inc. | 1,4,5,6-tetrahydro-pyridazine derivatives, their preparation and their use as neuraminidase inhibitors |
| AUPP913999A0 (en) * | 1999-03-12 | 1999-04-01 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| ES2198244T3 (es) * | 1999-06-11 | 2004-02-01 | F. Hoffmann-La Roche Ag | Procedimiento para la preparacion de inhibidor ro-64-0796 de la neuraminidasa. |
| DE19930177B4 (de) | 1999-06-30 | 2007-02-08 | Nikolai Vladimirovich Bovin | Intermolekular assoziierende Verbindungen und deren Verwendung |
| US6593314B1 (en) | 1999-10-19 | 2003-07-15 | Abbott Laboratories | Neuraminidase inhibitors |
| BR0010525A (pt) * | 1999-10-19 | 2002-11-26 | Abbott Lab | cido 1-ciclo-hexeno-1-carboxìlico e 1-ciclo-hexeno-1carboxilatos como inibidores de neuraminidase |
| US6627396B1 (en) * | 1999-10-28 | 2003-09-30 | The Regents Of The University Of California | Influenza sensor |
| JP2001131144A (ja) | 1999-11-02 | 2001-05-15 | Sagami Chem Res Center | 7−アザビシクロ[4.1.0]ヘプト−3−エン−3−カルボン酸エステル類の製造方法 |
| US6462226B1 (en) | 1999-12-03 | 2002-10-08 | Hoffmann-La Roche Inc. | Process for the preparation of 4,5-diamino shikimic acid derivatives |
| EP1486499A1 (en) | 1999-12-27 | 2004-12-15 | Sagami Chemical Research Center | Endo-2,3-epoxy-7-oxabicylco[2.2.1]heptane-endo-5-carboxylic acid derivative |
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| AU2001281846B2 (en) | 2000-06-27 | 2006-04-27 | Cheplapharm Arzneimittel Gmbh | Method for preparing a composition |
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| US7122684B2 (en) | 2003-03-13 | 2006-10-17 | Roche Colorado Corporation | Process for preparing 1,2-diamino compounds |
| DE602004031115D1 (de) | 2003-06-16 | 2011-03-03 | Acad Of Science Czech Republic | Pyrimidinverbindungen mit phosphonatgruppen als antivirale nucleotidanaloga |
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| US7687658B2 (en) | 2005-11-25 | 2010-03-30 | Hetero Drugs Limited | Process for oseltamivir phosphate |
| KR100819759B1 (ko) | 2005-12-01 | 2008-04-07 | (주)파인켐 | 아자이드 화합물의 폭발성을 제거한 공정을 이용한 1,2-다이아미노 화합물 또는 이의 부가염 제조 방법 |
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| CN101486664B (zh) * | 2008-12-31 | 2013-09-04 | 北京大学深圳研究生院 | 用作流感病毒神经氨酸酶抑制剂的多取代五元环小分子化合物 |
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| DE102011117128A1 (de) | 2011-10-28 | 2013-05-02 | Christian-Albrechts-Universität Zu Kiel | Verbindungen zur Therapie der Influenza |
| RU2469020C1 (ru) * | 2011-11-08 | 2012-12-10 | Александр Васильевич Иващенко | (3r,4r,5s)-5-амино-4-ациламино-3-(1-этил-пропокси)-циклогекс-1-ен-карбоновые кислоты, их эфиры и способ применения |
| RU2489422C1 (ru) * | 2012-05-12 | 2013-08-10 | Александр Васильевич Иващенко | Фторзамещенные (3r,4r,5s)-5-гуанидино-4-ациламино-3-(пентан-3-илокси)циклогексен-1-карбоновые кислоты, их эфиры и способ применения |
| RU2521593C1 (ru) * | 2013-02-27 | 2014-06-27 | Общество с ограниченной ответственностью "Интеллектуальный Диалог" | Моно и дифторзамещенные этил (3r,4r,5s)-5-азидо-4-ацетиламино-3-(1-этилпропокси)-циклогексен-1-карбоксилаты, способ получения и применения |
| JP6453050B2 (ja) * | 2013-11-15 | 2019-01-16 | 国立大学法人富山大学 | 2−デオキシ−2,3−ジデヒドロシアル酸誘導体およびその製造法 |
| CN103819357B (zh) * | 2014-01-28 | 2016-03-16 | 浙江大学 | (-)-有效霉醇叠氮四乙酸酯的制备方法 |
| KR20160124764A (ko) | 2014-02-14 | 2016-10-28 | 도아 에이요 가부시키가이샤 | 고리형 탄화수소 화합물 |
| US20170100385A1 (en) | 2014-05-12 | 2017-04-13 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pharmaceutical compositions comprising danirixin for treating infectious diseases |
| US9392814B2 (en) | 2014-06-06 | 2016-07-19 | Nicholas J. Singer | Delivery system for drinks |
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| KR102339817B1 (ko) | 2016-06-30 | 2021-12-16 | 한미약품 주식회사 | 오셀타미비어 함유 경구용 고형제제 및 그 제조방법 |
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| JP6804790B1 (ja) | 2017-12-07 | 2020-12-23 | エモリー ユニバーシティー | N4−ヒドロキシシチジンおよび誘導体ならびにそれらに関連する抗ウイルス用途 |
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| GB9416365D0 (en) * | 1994-08-12 | 1994-10-05 | Glaxo Group Ltd | Medicaments |
| US5512596A (en) * | 1994-09-02 | 1996-04-30 | Gilead Sciences, Inc. | Aromatic compounds |
| WO1996014314A2 (en) | 1994-11-04 | 1996-05-17 | Gilead Sciences, Inc. | Thiepane compounds inhibiting and detecting hiv protease |
| US5866601A (en) * | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
| BR9607098B8 (pt) * | 1995-02-27 | 2014-11-18 | Gilead Sciences Inc | Composto e composição farmacêutica. |
| US5602277A (en) | 1995-03-30 | 1997-02-11 | Biocryst Pharmaceuticals, Inc. | Substituted benzene derivatives useful as neuraminidase inhibitors |
| US5714509A (en) * | 1995-05-03 | 1998-02-03 | The University Of Alabama | Inhibitors of bacterial sialidase and methods of making and using the same |
| GB9510141D0 (en) | 1995-05-19 | 1995-07-12 | Biota Scient Management | Chemical compounds |
| GB9525389D0 (en) | 1995-12-12 | 1996-02-14 | Biota Scient Management Ltd | Chemical compounds |
| HUP9801766A3 (en) * | 1995-05-19 | 2000-09-28 | Biota Scient Managemant Pty Lt | 6-carboxamido dihydropyran derivatives, process for producing them and medicaments containing the same |
| GB9516276D0 (en) * | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
| US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
| DE69711395T2 (de) | 1996-08-23 | 2002-11-07 | Gilead Sciences, Inc. | Verfahren zur herstellung von cyclohexen-carboxylatderivate |
| US5859284A (en) | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| US5948816A (en) * | 1996-09-10 | 1999-09-07 | Daikin Industries, Ltd. | 4-substituted-2,7-dideoxy-7-fluoro-2,3-didehydro-sialic acid compounds |
| US5886213A (en) | 1997-08-22 | 1999-03-23 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
-
1996
- 1996-02-26 BR BRPI9607098-6B8D patent/BR9607098B8/pt unknown
- 1996-02-26 UA UA97094796A patent/UA56128C2/uk unknown
- 1996-02-26 MX MX9706496A patent/MX9706496A/es unknown
- 1996-02-26 EP EP96912404A patent/EP0759917B1/en not_active Expired - Lifetime
- 1996-02-26 DE DE69607704T patent/DE69607704T2/de not_active Expired - Lifetime
- 1996-02-26 SI SI9620042A patent/SI9620042A/sl not_active IP Right Cessation
- 1996-02-26 JP JP52644296A patent/JP3300365B2/ja not_active Expired - Lifetime
- 1996-02-26 HU HU9800026A patent/HU228450B1/hu unknown
- 1996-02-26 PL PL96322000A patent/PL194173B1/pl unknown
- 1996-02-26 PT PT96912404T patent/PT759917E/pt unknown
- 1996-02-26 KR KR1019970705932A patent/KR100447096B1/ko not_active Expired - Lifetime
- 1996-02-26 CZ CZ0269097A patent/CZ297945B6/cs not_active IP Right Cessation
- 1996-02-26 NZ NZ306625A patent/NZ306625A/xx not_active IP Right Cessation
- 1996-02-26 DE DE69635231T patent/DE69635231T2/de not_active Expired - Lifetime
- 1996-02-26 CN CNB961901330A patent/CN1185223C/zh not_active Expired - Lifetime
- 1996-02-26 BR BR9607098A patent/BR9607098A/pt not_active IP Right Cessation
- 1996-02-26 ES ES99117934T patent/ES2249863T3/es not_active Expired - Lifetime
- 1996-02-26 US US08/606,624 patent/US5952375A/en not_active Expired - Lifetime
- 1996-02-26 AT AT96912404T patent/ATE191711T1/de active
- 1996-02-26 AT AT99117934T patent/ATE305453T1/de active
- 1996-02-26 AU AU53571/96A patent/AU720933B2/en not_active Expired
- 1996-02-26 CN CNB011247142A patent/CN100409844C/zh not_active Expired - Lifetime
- 1996-02-26 DK DK96912404T patent/DK0759917T3/da active
- 1996-02-26 SG SG1997004840A patent/SG45864A1/en unknown
- 1996-02-26 DE DE0759917T patent/DE759917T1/de active Pending
- 1996-02-26 WO PCT/US1996/002882 patent/WO1996026933A1/en not_active Ceased
- 1996-02-26 DE DE2002199052 patent/DE10299052I1/de active Pending
- 1996-02-26 RU RU97116714/04A patent/RU2181357C2/ru active
- 1996-02-26 ES ES96912404T patent/ES2118674T3/es not_active Expired - Lifetime
- 1996-05-24 US US08/653,034 patent/US20050176758A1/en not_active Abandoned
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1997
- 1997-08-26 NO NO19973908A patent/NO318455B1/no not_active IP Right Cessation
-
1999
- 1999-04-08 US US09/288,091 patent/US6225341B1/en not_active Expired - Lifetime
-
2000
- 2000-07-07 GR GR20000401599T patent/GR3033914T3/el unknown
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2001
- 2001-08-24 JP JP2001255372A patent/JP4234917B2/ja not_active Expired - Lifetime
-
2002
- 2002-10-29 NL NL300105C patent/NL300105I2/nl unknown
- 2002-12-11 LU LU90991C patent/LU90991I2/fr unknown
-
2005
- 2005-07-15 JP JP2005207906A patent/JP2006036770A/ja not_active Withdrawn
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