JP2001524950A - 活性物質の制御された放出のための薬剤組成物 - Google Patents

活性物質の制御された放出のための薬剤組成物

Info

Publication number
JP2001524950A
JP2001524950A JP53995798A JP53995798A JP2001524950A JP 2001524950 A JP2001524950 A JP 2001524950A JP 53995798 A JP53995798 A JP 53995798A JP 53995798 A JP53995798 A JP 53995798A JP 2001524950 A JP2001524950 A JP 2001524950A
Authority
JP
Japan
Prior art keywords
matrix
active substance
release
pharmaceutical composition
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP53995798A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001524950A5 (enExample
Inventor
ファナラ,ドメニコ
ベルウェール,モニーク
ブケール,アンヌ
デリールス,ミッシェル
Original Assignee
ユセベ,ソシエテ アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ユセベ,ソシエテ アノニム filed Critical ユセベ,ソシエテ アノニム
Publication of JP2001524950A publication Critical patent/JP2001524950A/ja
Publication of JP2001524950A5 publication Critical patent/JP2001524950A5/ja
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP53995798A 1997-03-14 1998-03-13 活性物質の制御された放出のための薬剤組成物 Ceased JP2001524950A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BE9700225 1997-03-14
BE9700225A BE1011045A3 (fr) 1997-03-14 1997-03-14 Compositions pharmaceutiques pour la liberation controlee de substances actives.
PCT/BE1998/000033 WO1998041194A1 (fr) 1997-03-14 1998-03-13 Compositions pharmaceutiques pour la liberation controlee de substances actives

Publications (2)

Publication Number Publication Date
JP2001524950A true JP2001524950A (ja) 2001-12-04
JP2001524950A5 JP2001524950A5 (enExample) 2004-10-28

Family

ID=3890403

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53995798A Ceased JP2001524950A (ja) 1997-03-14 1998-03-13 活性物質の制御された放出のための薬剤組成物

Country Status (19)

Country Link
US (3) US6699502B1 (enExample)
EP (1) EP1007005B1 (enExample)
JP (1) JP2001524950A (enExample)
KR (1) KR100500775B1 (enExample)
CN (1) CN1126536C (enExample)
AT (1) ATE275943T1 (enExample)
AU (1) AU736052B2 (enExample)
BE (1) BE1011045A3 (enExample)
BR (1) BR9808239A (enExample)
CA (1) CA2283133C (enExample)
DE (1) DE69826290T2 (enExample)
ES (1) ES2229483T3 (enExample)
ID (1) ID22980A (enExample)
IL (1) IL131292A (enExample)
NZ (1) NZ337345A (enExample)
PL (1) PL190735B1 (enExample)
RO (1) RO120602B1 (enExample)
RU (1) RU2179017C2 (enExample)
WO (1) WO1998041194A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006510639A (ja) * 2002-12-06 2006-03-30 ユセベ ファルシム ソシエテ アノニム エフレチリジン及びプソイドエフェドリンを含む錠剤
JP2009541341A (ja) * 2006-06-19 2009-11-26 エーシーシーユー−ブレイク テクノロジーズ,インク. セグメント状の薬剤の剤形
JP2015131864A (ja) * 1998-10-01 2015-07-23 エラン ファーマ インターナショナル,リミティド 徐放性ナノ粒子組成物

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1050306A (ja) * 1996-07-31 1998-02-20 Toyota Autom Loom Works Ltd 水素吸蔵合金電極の製造方法
BE1011045A3 (fr) * 1997-03-14 1999-04-06 Ucb Sa Compositions pharmaceutiques pour la liberation controlee de substances actives.
US20050085498A1 (en) * 1998-05-28 2005-04-21 Byrd Edward A. Oral formulation of lipid soluble thiamine, lipoic acid, creatine derivative, and L-arginine alpha-ketoglutarate
JP2001107258A (ja) * 1999-10-06 2001-04-17 Hitachi Ltd 無電解銅めっき方法とめっき装置および多層配線基板
WO2001032148A1 (en) 1999-10-29 2001-05-10 Euro-Celtique, S.A. Controlled release hydrocodone formulations
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
EP1118321A1 (fr) * 2000-01-14 2001-07-25 Ucb, S.A. Compositions pharmaceutiques solides pour la libération contrôlée de substances actives
US6242003B1 (en) 2000-04-13 2001-06-05 Novartis Ag Organic compounds
GB0009522D0 (en) * 2000-04-19 2000-06-07 Smithkline Beecham Plc Composition
CN101317825A (zh) 2000-10-30 2008-12-10 欧罗赛铁克股份有限公司 控释氢可酮制剂
US20060127474A1 (en) 2001-04-11 2006-06-15 Oskar Kalb Pharmaceutical compositions comprising fluvastatin
PL206069B1 (pl) * 2001-06-28 2010-06-30 Ucb Farchim Sa Tabletka dwuwarstwowa zawierająca cetyryzynę i pseudoefedrynę
HRP20031057B1 (hr) 2001-06-28 2013-05-31 Ucb Farchim Sa, Z.I. Planchy Tableta koja sadrži cetirizin i pseudoefedrin
US20030092724A1 (en) * 2001-09-18 2003-05-15 Huaihung Kao Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic
AU2003202550A1 (en) * 2002-01-09 2003-07-24 Ucb, S.A. Pharmaceutical formulations with modified release
PL372904A1 (en) * 2002-04-04 2005-08-08 Pfizer Products Inc. Palatable chewable tablet
AU2003272601B2 (en) * 2002-09-20 2009-05-07 Alpharma Pharmaceuticals, Llc Sustained-release opioid formulations and methods of use
US8487002B2 (en) * 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
TWI319713B (en) * 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
US20050281875A1 (en) * 2003-12-17 2005-12-22 Sovereign Pharmaceuticals, Ltd. Promethazine containing dosage form
US20050266032A1 (en) * 2003-12-17 2005-12-01 Sovereign Pharmaceuticals, Ltd. Dosage form containing multiple drugs
US20060029664A1 (en) * 2004-08-04 2006-02-09 Sovereign Pharmaceuticals, Ltd. Dosage form containing carbetapentane and another drug
US20050232987A1 (en) * 2004-03-12 2005-10-20 Viswanathan Srinivasan Dosage form containing a morphine derivative and another drug
US20050232986A1 (en) * 2003-12-17 2005-10-20 David Brown Dosage form containing promethazine and another drug
US9492541B2 (en) * 2004-09-14 2016-11-15 Sovereign Pharmaceuticals, Llc Phenylepherine containing dosage form
US7897172B2 (en) * 2004-05-18 2011-03-01 L. Perrigo Company Tablets exhibiting reduced drug release variability
US9308164B2 (en) 2004-06-30 2016-04-12 Sovereign Pharmaceuticals, Llc Hyoscyamine dosage form
US20070003622A1 (en) * 2004-12-16 2007-01-04 Sovereign Pharmaceuticals, Ltd. Diphenhydramine containing dosage form
WO2006022996A2 (en) * 2004-08-04 2006-03-02 Sovereign Pharmaceuticals, Ltd. Dosage form containing multiple drugs
US9592197B2 (en) * 2004-12-16 2017-03-14 Sovereign Pharmaceuticals, Llc Dosage form containing diphenhydramine and another drug
US7529255B2 (en) * 2005-04-21 2009-05-05 Microsoft Corporation Peer-to-peer multicasting using multiple transport protocols
SI1909764T1 (sl) * 2005-07-26 2015-01-30 Ucb Pharma, S.A. Farmacevtski sestavki, ki obsegajo levetiracetam in postopek za njihovo pripravo
US8795723B2 (en) 2005-09-09 2014-08-05 Angelini Pharma Inc. Sustained drug release compositions
JP5269595B2 (ja) * 2005-09-09 2013-08-21 アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー 1日1回投与用トラゾドン組成物
US20090317355A1 (en) * 2006-01-21 2009-12-24 Abbott Gmbh & Co. Kg, Abuse resistant melt extruded formulation having reduced alcohol interaction
US20090022798A1 (en) * 2007-07-20 2009-01-22 Abbott Gmbh & Co. Kg Formulations of nonopioid and confined opioid analgesics
JP2009523833A (ja) * 2006-01-21 2009-06-25 アボット ゲーエムベーハー ウント カンパニー カーゲー 乱用薬剤送達のための製剤および方法
US20100172989A1 (en) * 2006-01-21 2010-07-08 Abbott Laboratories Abuse resistant melt extruded formulation having reduced alcohol interaction
KR100753480B1 (ko) * 2006-01-27 2007-08-31 씨제이 주식회사 잘토프로펜 함유 서방성 정제 및 그 제조방법
US20070253927A1 (en) * 2006-04-13 2007-11-01 Gwenaelle Jegou Cosmetic compositions comprising at least one dielectrophile monomer and at least one radical initiator
US20100172984A1 (en) * 2006-06-06 2010-07-08 Bijay Kumar Padhi tablet dosage form comprising cetirizine and pseudoephedrine
US20080069891A1 (en) * 2006-09-15 2008-03-20 Cima Labs, Inc. Abuse resistant drug formulation
US8765178B2 (en) * 2006-07-19 2014-07-01 Watson Laboratories, Inc. Controlled release formulations and associated methods
US8445018B2 (en) 2006-09-15 2013-05-21 Cima Labs Inc. Abuse resistant drug formulation
US8045677B2 (en) 2006-09-25 2011-10-25 Koninklijke Philips Electronics N V Eindhoven Shifting an object for complete trajectories in rotational X-ray imaging
SI2124556T1 (sl) 2006-10-09 2015-01-30 Charleston Laboratories, Inc. Farmacevtske sestave
WO2008064192A2 (en) 2006-11-21 2008-05-29 Mcneil-Ppc, Inc. Modified release analgesic suspensions
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
AU2008314454A1 (en) * 2007-10-16 2009-04-23 Labopharm (Barbados) Limited Bilayer composition for the sustained release of acetaminophen and tramadol
EP2219677A1 (en) * 2007-11-21 2010-08-25 The Procter & Gamble Company Preparations, methods and kits useful for treatment of cough
CA2707980C (en) 2007-12-17 2015-05-12 Labopharm Inc. Misuse preventative, controlled release formulation
EP2240022B1 (en) 2008-01-09 2016-12-28 Charleston Laboratories, Inc. Bilayered tablets comprising oxycodone and promethazine
JP2011511782A (ja) 2008-02-12 2011-04-14 アボット・ラボラトリーズ 長期放出性ヒドロコドンアセトアミノフェンならびにその関連方法および用途
CA2746888C (en) 2008-12-16 2015-05-12 Labopharm (Barbados) Limited Misuse preventative, controlled release formulation
EP2381937A2 (en) 2008-12-31 2011-11-02 Upsher-Smith Laboratories, Inc. Opioid-containing oral pharmaceutical compositions and methods
EP3311667A1 (en) 2009-07-08 2018-04-25 Charleston Laboratories, Inc. Pharmaceutical compositions
BR112012008317A2 (pt) 2009-09-17 2016-03-22 Upsher Smith Lab Inc produto de liberação sustentada compreendendo uma combinação de uma amina não-opioide e uma droga anti-inflamatória não-esteroidal
MX2012012991A (es) 2010-05-11 2012-11-30 Cima Labs Inc Formas de dosificacion oral de liberacion prolongada resistentes al alcohol y que contienen metoprolol.
CN102302497A (zh) * 2011-05-18 2012-01-04 天圣制药集团股份有限公司 一种治疗过敏性鼻炎的制剂及其制备方法
PL2956120T3 (pl) 2013-02-13 2020-08-10 The Procter & Gamble Company Leki o smaku anyżu
KR102070076B1 (ko) * 2013-05-03 2020-01-29 주식회사 제닉 탄산 함유 입자를 포함하는 필름
WO2015065547A1 (en) 2013-10-31 2015-05-07 Cima Labs Inc. Immediate release abuse-deterrent granulated dosage forms
JP6461186B2 (ja) 2014-03-11 2019-01-30 レッド ヒル バイオファーマ リミテッドRedHill Biopharma Ltd. 悪心、嘔吐または下痢の症状を処置するためのオンダンセトロン徐放固形製剤
US10179109B2 (en) 2016-03-04 2019-01-15 Charleston Laboratories, Inc. Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates
RU2687715C1 (ru) * 2018-05-07 2019-05-15 Федеральное государственное бюджетное учреждение науки Институт горного дела Дальневосточного отделения Российской академии наук Способ комбинированной разработки россыпных месторождений золота
US20220062200A1 (en) 2019-05-07 2022-03-03 Clexio Biosciences Ltd. Abuse-deterrent dosage forms containing esketamine
US11324707B2 (en) 2019-05-07 2022-05-10 Clexio Biosciences Ltd. Abuse-deterrent dosage forms containing esketamine
KR102073185B1 (ko) * 2019-07-16 2020-02-04 (주)위바이오트리 활성성분을 포함하는 변성 다중층 수산화물 구조체를 포함하는 금속 수산화물 복합체 및 이의 제조 방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US477033A (en) * 1892-06-14 Bicycle
US4684516A (en) 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
EP0205336B1 (en) * 1985-06-11 1991-09-11 Teijin Limited Oral sustained release pharmaceutical preparation
DE3524572A1 (de) 1985-07-10 1987-01-15 Thomae Gmbh Dr K Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung
US4756911A (en) * 1986-04-16 1988-07-12 E. R. Squibb & Sons, Inc. Controlled release formulation
JPS6396126A (ja) 1986-10-13 1988-04-27 Taisho Pharmaceut Co Ltd 安定化組成物
IT1201136B (it) 1987-01-13 1989-01-27 Resa Farma Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive
GB8724763D0 (en) 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations
IE60383B1 (en) * 1988-05-27 1994-07-13 Elan Corp Plc Controlled release pharmaceutical formulation
US4990535A (en) * 1989-05-03 1991-02-05 Schering Corporation Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
US5411748A (en) 1992-10-22 1995-05-02 Song Moon K Prostate extract supplemented with zinc
US5314697A (en) * 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
DE69508580T2 (de) * 1994-06-15 1999-09-23 Dumex Alpharma As Pellets
RU2065299C1 (ru) * 1994-07-15 1996-08-20 Акционерное общество закрытого типа "Олвик" Ноотропное и транквилизирующее средство
EP0811374A1 (en) * 1996-05-29 1997-12-10 Pfizer Inc. Combination dosage form comprising cetirizine and pseudoephedrine
AU5609998A (en) * 1997-01-10 1998-08-03 Abbott Laboratories Tablet for the controlled release of active agents
BE1011045A3 (fr) * 1997-03-14 1999-04-06 Ucb Sa Compositions pharmaceutiques pour la liberation controlee de substances actives.

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015131864A (ja) * 1998-10-01 2015-07-23 エラン ファーマ インターナショナル,リミティド 徐放性ナノ粒子組成物
JP2006510639A (ja) * 2002-12-06 2006-03-30 ユセベ ファルシム ソシエテ アノニム エフレチリジン及びプソイドエフェドリンを含む錠剤
JP2009541341A (ja) * 2006-06-19 2009-11-26 エーシーシーユー−ブレイク テクノロジーズ,インク. セグメント状の薬剤の剤形

Also Published As

Publication number Publication date
BE1011045A3 (fr) 1999-04-06
CN1250371A (zh) 2000-04-12
EP1007005A1 (fr) 2000-06-14
KR20000076269A (ko) 2000-12-26
DE69826290D1 (de) 2004-10-21
AU736052B2 (en) 2001-07-26
US7083807B2 (en) 2006-08-01
WO1998041194A1 (fr) 1998-09-24
BR9808239A (pt) 2000-05-16
US20040086563A1 (en) 2004-05-06
ES2229483T3 (es) 2005-04-16
RU2179017C2 (ru) 2002-02-10
CN1126536C (zh) 2003-11-05
CA2283133C (fr) 2006-07-25
DE69826290T2 (de) 2005-02-17
IL131292A0 (en) 2001-01-28
US6699502B1 (en) 2004-03-02
NZ337345A (en) 2000-04-28
US20020110596A1 (en) 2002-08-15
HK1026152A1 (en) 2000-12-08
KR100500775B1 (ko) 2005-07-12
ID22980A (id) 1999-12-23
AU6387398A (en) 1998-10-12
PL190735B1 (pl) 2005-12-30
ATE275943T1 (de) 2004-10-15
RO120602B1 (ro) 2006-05-30
CA2283133A1 (fr) 1998-09-24
PL335832A1 (en) 2000-05-22
EP1007005B1 (fr) 2004-09-15
IL131292A (en) 2004-07-25

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