DE69826290D1 - Pharmazeutische zusammensetzungen zur kontrollierten freigabe von wirkstoffen - Google Patents

Pharmazeutische zusammensetzungen zur kontrollierten freigabe von wirkstoffen

Info

Publication number
DE69826290D1
DE69826290D1 DE69826290T DE69826290T DE69826290D1 DE 69826290 D1 DE69826290 D1 DE 69826290D1 DE 69826290 T DE69826290 T DE 69826290T DE 69826290 T DE69826290 T DE 69826290T DE 69826290 D1 DE69826290 D1 DE 69826290D1
Authority
DE
Germany
Prior art keywords
matrices
composition
pharmaceutical compositions
mixtures
controlled release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69826290T
Other languages
English (en)
Other versions
DE69826290T2 (de
Inventor
Domenico Fanara
Monique Berwaer
Anne Bouquelle
Michel Deleers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB SA
Original Assignee
UCB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB SA filed Critical UCB SA
Publication of DE69826290D1 publication Critical patent/DE69826290D1/de
Application granted granted Critical
Publication of DE69826290T2 publication Critical patent/DE69826290T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69826290T 1997-03-14 1998-03-13 Pharmazeutische zusammensetzungen zur kontrollierten freigabe von wirkstoffen Expired - Fee Related DE69826290T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BE9700225 1997-03-14
BE9700225A BE1011045A3 (fr) 1997-03-14 1997-03-14 Compositions pharmaceutiques pour la liberation controlee de substances actives.
PCT/BE1998/000033 WO1998041194A1 (fr) 1997-03-14 1998-03-13 Compositions pharmaceutiques pour la liberation controlee de substances actives

Publications (2)

Publication Number Publication Date
DE69826290D1 true DE69826290D1 (de) 2004-10-21
DE69826290T2 DE69826290T2 (de) 2005-02-17

Family

ID=3890403

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69826290T Expired - Fee Related DE69826290T2 (de) 1997-03-14 1998-03-13 Pharmazeutische zusammensetzungen zur kontrollierten freigabe von wirkstoffen

Country Status (20)

Country Link
US (3) US6699502B1 (de)
EP (1) EP1007005B1 (de)
JP (1) JP2001524950A (de)
KR (1) KR100500775B1 (de)
CN (1) CN1126536C (de)
AT (1) ATE275943T1 (de)
AU (1) AU736052B2 (de)
BE (1) BE1011045A3 (de)
BR (1) BR9808239A (de)
CA (1) CA2283133C (de)
DE (1) DE69826290T2 (de)
ES (1) ES2229483T3 (de)
HK (1) HK1026152A1 (de)
ID (1) ID22980A (de)
IL (1) IL131292A (de)
NZ (1) NZ337345A (de)
PL (1) PL190735B1 (de)
RO (1) RO120602B1 (de)
RU (1) RU2179017C2 (de)
WO (1) WO1998041194A1 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1050306A (ja) * 1996-07-31 1998-02-20 Toyota Autom Loom Works Ltd 水素吸蔵合金電極の製造方法
BE1011045A3 (fr) * 1997-03-14 1999-04-06 Ucb Sa Compositions pharmaceutiques pour la liberation controlee de substances actives.
US20050085498A1 (en) * 1998-05-28 2005-04-21 Byrd Edward A. Oral formulation of lipid soluble thiamine, lipoic acid, creatine derivative, and L-arginine alpha-ketoglutarate
WO2000018374A1 (en) * 1998-10-01 2000-04-06 Elan Pharma International, Ltd. Controlled release nanoparticulate compositions
JP2001107258A (ja) * 1999-10-06 2001-04-17 Hitachi Ltd 無電解銅めっき方法とめっき装置および多層配線基板
MXPA02004293A (es) 1999-10-29 2002-10-31 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada..
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
EP1118321A1 (de) * 2000-01-14 2001-07-25 Ucb, S.A. Feste pharmazeutische Zusammensetzungen für die kontrollierte Freisetzung von aktiven Substanzen
US6242003B1 (en) 2000-04-13 2001-06-05 Novartis Ag Organic compounds
GB0009522D0 (en) * 2000-04-19 2000-06-07 Smithkline Beecham Plc Composition
EP1337244A4 (de) * 2000-10-30 2006-01-11 Euro Celtique Sa Hydrocodon-formulierungen mit kontrollierter freisetzung
US20060127474A1 (en) 2001-04-11 2006-06-15 Oskar Kalb Pharmaceutical compositions comprising fluvastatin
CN100490809C (zh) * 2001-06-28 2009-05-27 Ucb法奇姆股份有限公司 包含西替利嗪和伪麻黄碱的片剂
DE60232445D1 (de) * 2001-06-28 2009-07-09 Ucb Farchim Sa Cetirizin und pseudoephedrin enthaltende tablette
US20030092724A1 (en) * 2001-09-18 2003-05-15 Huaihung Kao Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic
WO2003057198A1 (fr) * 2002-01-09 2003-07-17 Ucb, S.A. Compositions pharmaceutiques a liberation modifiee
PL372904A1 (en) * 2002-04-04 2005-08-08 Pfizer Products Inc. Palatable chewable tablet
EP1545468A4 (de) * 2002-09-20 2007-06-20 Alpharma Inc Opioid-formulierungen mit verz gerter freisetzung und anwendungsverfahren
TWI319713B (en) * 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US8487002B2 (en) * 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
JP2006510639A (ja) * 2002-12-06 2006-03-30 ユセベ ファルシム ソシエテ アノニム エフレチリジン及びプソイドエフェドリンを含む錠剤
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
US20050232986A1 (en) * 2003-12-17 2005-10-20 David Brown Dosage form containing promethazine and another drug
US20050281875A1 (en) * 2003-12-17 2005-12-22 Sovereign Pharmaceuticals, Ltd. Promethazine containing dosage form
US9492541B2 (en) * 2004-09-14 2016-11-15 Sovereign Pharmaceuticals, Llc Phenylepherine containing dosage form
US20060029664A1 (en) * 2004-08-04 2006-02-09 Sovereign Pharmaceuticals, Ltd. Dosage form containing carbetapentane and another drug
US20050266032A1 (en) * 2003-12-17 2005-12-01 Sovereign Pharmaceuticals, Ltd. Dosage form containing multiple drugs
US20050232987A1 (en) * 2004-03-12 2005-10-20 Viswanathan Srinivasan Dosage form containing a morphine derivative and another drug
US7897172B2 (en) * 2004-05-18 2011-03-01 L. Perrigo Company Tablets exhibiting reduced drug release variability
US9308164B2 (en) 2004-06-30 2016-04-12 Sovereign Pharmaceuticals, Llc Hyoscyamine dosage form
US9592197B2 (en) * 2004-12-16 2017-03-14 Sovereign Pharmaceuticals, Llc Dosage form containing diphenhydramine and another drug
US20070003622A1 (en) * 2004-12-16 2007-01-04 Sovereign Pharmaceuticals, Ltd. Diphenhydramine containing dosage form
WO2006022996A2 (en) * 2004-08-04 2006-03-02 Sovereign Pharmaceuticals, Ltd. Dosage form containing multiple drugs
US7529255B2 (en) * 2005-04-21 2009-05-05 Microsoft Corporation Peer-to-peer multicasting using multiple transport protocols
NZ554157A (en) * 2005-07-26 2010-12-24 Glaxo Smithkline Trading Services Ltd Pharmaceutical compositions comprising levetiracetam and process for their preparation
CN101242856A (zh) 2005-09-09 2008-08-13 莱博法姆公司 持续药物释放的组合物
US20090317355A1 (en) * 2006-01-21 2009-12-24 Abbott Gmbh & Co. Kg, Abuse resistant melt extruded formulation having reduced alcohol interaction
EP1991207A2 (de) * 2006-01-21 2008-11-19 Abbott GmbH & Co. KG Dosierungsform und verfahren zur abgabe von arzneimitteln, die missbraucht werden können
US20090022798A1 (en) * 2007-07-20 2009-01-22 Abbott Gmbh & Co. Kg Formulations of nonopioid and confined opioid analgesics
US20100172989A1 (en) * 2006-01-21 2010-07-08 Abbott Laboratories Abuse resistant melt extruded formulation having reduced alcohol interaction
KR100753480B1 (ko) * 2006-01-27 2007-08-31 씨제이 주식회사 잘토프로펜 함유 서방성 정제 및 그 제조방법
US20070253927A1 (en) * 2006-04-13 2007-11-01 Gwenaelle Jegou Cosmetic compositions comprising at least one dielectrophile monomer and at least one radical initiator
US20100172984A1 (en) * 2006-06-06 2010-07-08 Bijay Kumar Padhi tablet dosage form comprising cetirizine and pseudoephedrine
US20080069891A1 (en) 2006-09-15 2008-03-20 Cima Labs, Inc. Abuse resistant drug formulation
EP2029116A4 (de) * 2006-06-19 2012-07-04 Accu Break Technologies Inc Segmentierte pharmazeutische dosierungsformen
US8765178B2 (en) * 2006-07-19 2014-07-01 Watson Laboratories, Inc. Controlled release formulations and associated methods
US8445018B2 (en) 2006-09-15 2013-05-21 Cima Labs Inc. Abuse resistant drug formulation
US8045677B2 (en) 2006-09-25 2011-10-25 Koninklijke Philips Electronics N V Eindhoven Shifting an object for complete trajectories in rotational X-ray imaging
EP2813144A1 (de) 2006-10-09 2014-12-17 Charleston Laboratories, Inc. Analgetische Zusammensetzungen enthaltend ein Antihistamin
JP2010510320A (ja) 2006-11-21 2010-04-02 マクニール−ピーピーシー・インコーポレーテツド 改変型放出鎮痛性懸濁液
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
US8895066B2 (en) * 2007-10-16 2014-11-25 Paladin Labs Inc. Bilayer composition for the sustained release of acetaminophen and tramadol
CN101868253A (zh) * 2007-11-21 2010-10-20 宝洁公司 可用于咳嗽治疗的制剂、方法和试剂盒
RU2010129907A (ru) 2007-12-17 2012-01-27 Лабофарм Инк. (CA) Лекарственная форма с контролируемым высвобождением, предотвращающая неправильное употребление
WO2009089494A2 (en) * 2008-01-09 2009-07-16 Charleston Laboratories, Inc. Pharmaceutical compositions
JP2011511782A (ja) 2008-02-12 2011-04-14 アボット・ラボラトリーズ 長期放出性ヒドロコドンアセトアミノフェンならびにその関連方法および用途
CA2746888C (en) 2008-12-16 2015-05-12 Labopharm (Barbados) Limited Misuse preventative, controlled release formulation
AU2009332963B2 (en) 2008-12-31 2015-02-05 Upsher-Smith Laboratories, Llc Opioid-containing oral pharmaceutical compositions and methods
EP2451274B1 (de) 2009-07-08 2017-10-04 Charleston Laboratories, Inc. Pharmazeutische zusammensetzungen
EP2477610A1 (de) 2009-09-17 2012-07-25 Upsher-Smith Laboratories, Inc. Verzögert freigesetztes produkt mit einer kombination aus einem nichtopioiden amin und einem nichtsteroiden entzündungshemmenden mittel
US8927025B2 (en) 2010-05-11 2015-01-06 Cima Labs Inc. Alcohol-resistant metoprolol-containing extended-release oral dosage forms
CN102302497A (zh) * 2011-05-18 2012-01-04 天圣制药集团股份有限公司 一种治疗过敏性鼻炎的制剂及其制备方法
PL2956120T3 (pl) 2013-02-13 2020-08-10 The Procter & Gamble Company Leki o smaku anyżu
KR102070076B1 (ko) * 2013-05-03 2020-01-29 주식회사 제닉 탄산 함유 입자를 포함하는 필름
WO2015065547A1 (en) 2013-10-31 2015-05-07 Cima Labs Inc. Immediate release abuse-deterrent granulated dosage forms
MX2016011734A (es) * 2014-03-11 2017-02-13 Redhill Biopharma Ltd Formas de dosificacion sólida de liberación extendida de onndasetrón para trtar bien sea síntomas de náusea, vómito o diarrea.
WO2017152130A1 (en) 2016-03-04 2017-09-08 Charleston Laboratories, Inc. Pharmaceutical compositions
RU2687715C1 (ru) * 2018-05-07 2019-05-15 Федеральное государственное бюджетное учреждение науки Институт горного дела Дальневосточного отделения Российской академии наук Способ комбинированной разработки россыпных месторождений золота
US20220062200A1 (en) 2019-05-07 2022-03-03 Clexio Biosciences Ltd. Abuse-deterrent dosage forms containing esketamine
EP3965733A4 (de) 2019-05-07 2023-01-11 Clexio Biosciences Ltd. Esketamin enthaltende missbrauchssichere darreichungsformen
KR102073185B1 (ko) * 2019-07-16 2020-02-04 (주)위바이오트리 활성성분을 포함하는 변성 다중층 수산화물 구조체를 포함하는 금속 수산화물 복합체 및 이의 제조 방법

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US477033A (en) * 1892-06-14 Bicycle
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
DE3681348D1 (de) 1985-06-11 1991-10-17 Teijin Ltd Oral-arzneizubereitung mit retardwirkung.
DE3524572A1 (de) * 1985-07-10 1987-01-15 Thomae Gmbh Dr K Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung
US4756911A (en) * 1986-04-16 1988-07-12 E. R. Squibb & Sons, Inc. Controlled release formulation
JPS6396126A (ja) * 1986-10-13 1988-04-27 Taisho Pharmaceut Co Ltd 安定化組成物
IT1201136B (it) * 1987-01-13 1989-01-27 Resa Farma Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive
GB8724763D0 (en) * 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations
IE60383B1 (en) * 1988-05-27 1994-07-13 Elan Corp Plc Controlled release pharmaceutical formulation
US4990535A (en) * 1989-05-03 1991-02-05 Schering Corporation Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
US5411748A (en) * 1992-10-22 1995-05-02 Song Moon K Prostate extract supplemented with zinc
US5314697A (en) * 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
EP0765157B1 (de) * 1994-06-15 1999-03-24 Dumex-Alpharma A/S Pellets
EP0811374A1 (de) * 1996-05-29 1997-12-10 Pfizer Inc. Formulierung für ein Kombinationspräparat mit Cetirizin und Pseudoephedrin
EP0951279A1 (de) * 1997-01-10 1999-10-27 Abbott Laboratories Tablette für kontrollierte wirkstoffabgabe
BE1011045A3 (fr) * 1997-03-14 1999-04-06 Ucb Sa Compositions pharmaceutiques pour la liberation controlee de substances actives.

Also Published As

Publication number Publication date
PL335832A1 (en) 2000-05-22
US20040086563A1 (en) 2004-05-06
IL131292A0 (en) 2001-01-28
US7083807B2 (en) 2006-08-01
AU6387398A (en) 1998-10-12
ATE275943T1 (de) 2004-10-15
HK1026152A1 (en) 2000-12-08
JP2001524950A (ja) 2001-12-04
CA2283133A1 (fr) 1998-09-24
RU2179017C2 (ru) 2002-02-10
WO1998041194A1 (fr) 1998-09-24
EP1007005B1 (de) 2004-09-15
KR100500775B1 (ko) 2005-07-12
PL190735B1 (pl) 2005-12-30
BR9808239A (pt) 2000-05-16
EP1007005A1 (de) 2000-06-14
US6699502B1 (en) 2004-03-02
ES2229483T3 (es) 2005-04-16
RO120602B1 (ro) 2006-05-30
CN1126536C (zh) 2003-11-05
NZ337345A (en) 2000-04-28
KR20000076269A (ko) 2000-12-26
AU736052B2 (en) 2001-07-26
ID22980A (id) 1999-12-23
DE69826290T2 (de) 2005-02-17
BE1011045A3 (fr) 1999-04-06
CN1250371A (zh) 2000-04-12
US20020110596A1 (en) 2002-08-15
CA2283133C (fr) 2006-07-25
IL131292A (en) 2004-07-25

Similar Documents

Publication Publication Date Title
DE69826290D1 (de) Pharmazeutische zusammensetzungen zur kontrollierten freigabe von wirkstoffen
ES2402544T3 (es) Preparación pelicular rápidamente soluble
JP5523647B2 (ja) アデノシンアナログの経口投与
RU99119084A (ru) Фармацевтические композиции для контролируемого высвобождения активных веществ
ATE307569T1 (de) Gelierbare pharmazeutische zusammensetzungen
CA2464250A1 (en) Kit for the preparation of a pharmaceutical composition
GT199800113A (es) Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion.
DE60001835T2 (de) Mesalazine enthaltende pharmazeutische zusammensetzungen mit gesteuerte freisetzung
DE60211130D1 (de) Neue formulierung mit modifizierter freisetzung
CY1108863T1 (el) Φαρμακευτικο σκευασμα εκτεταμενης απελευθερωσης ανεξαρτητης απο το ρη
FR2774291B1 (fr) Specialite pharmaceutique sous forme galenique unitaire de comprimes a croquer ou a sucer, comprenant comme principe actif du fer element
US6521262B2 (en) Solid instant-release forms of administration and process for producing the same
KR20100032893A (ko) 안정적인 s-아데노실메티오닌의 염 및 이를 제조하기 위한 방법
HUP0000125A2 (hu) Folyékony alendronátkészítmények, valamint eljárás azok előállítására
JO2092B1 (en) Pharmaceutical compounds for restricted release of active substances
AR012266A1 (es) Composiciones farmaceuticas para la liberacion controlada de sustancias activas y procedimiento para su preparacion.
MA29560B1 (fr) Formulation a liberation prolongee de principes actifs de medicaments
EP1818050A1 (de) Stabile pharmazeutische Zusammensetzungen umfassend einen HMG-CoA-Reduktase Inhibitor
TH36198A (th) สารประกอบทางเภสัชกรรมสำหรับควบคุมการปลดปล่อยสารออกฤทธิ์
JP2002226371A (ja) プラバスタチンナトリウムの錠剤
MY102368A (en) Solid sustained-release composition
TH65639A (th) องค์ประกอบทางเภสัชกรรม
TH57858A3 (th) อนุพันธ์ของไทอะโซล

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee