JP2001516338A5 - - Google Patents
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- Publication number
- JP2001516338A5 JP2001516338A5 JP1998515702A JP51570298A JP2001516338A5 JP 2001516338 A5 JP2001516338 A5 JP 2001516338A5 JP 1998515702 A JP1998515702 A JP 1998515702A JP 51570298 A JP51570298 A JP 51570298A JP 2001516338 A5 JP2001516338 A5 JP 2001516338A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2684896P | 1996-09-27 | 1996-09-27 | |
| US60/026,848 | 1996-09-27 | ||
| PCT/US1997/016348 WO1998013340A1 (en) | 1996-09-27 | 1997-09-19 | β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001516338A JP2001516338A (ja) | 2001-09-25 |
| JP2001516338A5 true JP2001516338A5 (enExample) | 2005-05-12 |
Family
ID=21834136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51570298A Withdrawn JP2001516338A (ja) | 1996-09-27 | 1997-09-19 | マトリックスメタロプロテイナーゼ・インヒビターとしてのβ―スルホニルヒドロキサム酸 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6235928B1 (enExample) |
| EP (1) | EP0929519B1 (enExample) |
| JP (1) | JP2001516338A (enExample) |
| KR (1) | KR20000048639A (enExample) |
| CN (1) | CN1158254C (enExample) |
| AT (1) | ATE289590T1 (enExample) |
| AU (1) | AU726799B2 (enExample) |
| BR (1) | BR9712134A (enExample) |
| CA (1) | CA2266368A1 (enExample) |
| CZ (1) | CZ92399A3 (enExample) |
| DE (1) | DE69732571T2 (enExample) |
| EA (1) | EA001460B1 (enExample) |
| ES (1) | ES2236829T3 (enExample) |
| HU (1) | HUP0000145A3 (enExample) |
| ID (1) | ID21897A (enExample) |
| IL (1) | IL128900A0 (enExample) |
| NO (1) | NO312893B1 (enExample) |
| NZ (1) | NZ334729A (enExample) |
| PL (1) | PL332509A1 (enExample) |
| UA (1) | UA48262C2 (enExample) |
| WO (1) | WO1998013340A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998005635A1 (en) * | 1996-08-07 | 1998-02-12 | Darwin Discovery Limited | Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity |
| US6566384B1 (en) * | 1996-08-07 | 2003-05-20 | Darwin Discovery Ltd. | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity |
| KR20000048639A (ko) * | 1996-09-27 | 2000-07-25 | 로렌스 티. 마이젠헬더 | 매트릭스 메탈로프로테이나제 억제제인 베타-술포닐 히드록삼산 |
| JP4456183B2 (ja) | 1997-01-22 | 2010-04-28 | アベンテイス・フアーマシユーチカルズ・インコーポレーテツド | 置換β−チオカルボン酸類 |
| GB9702088D0 (en) | 1997-01-31 | 1997-03-19 | Pharmacia & Upjohn Spa | Matrix metalloproteinase inhibitors |
| US6172057B1 (en) | 1997-02-27 | 2001-01-09 | American Cyanamid Company | N-Hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors |
| WO1998039326A1 (en) | 1997-03-04 | 1998-09-11 | Monsanto Company | Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds |
| JP2002513407A (ja) * | 1997-03-04 | 2002-05-08 | モンサント カンパニー | Ｎ−ヒドロキシ４−スルホニルブタンアミド化合物 |
| US6187924B1 (en) * | 1997-11-12 | 2001-02-13 | Darwin Discovery, Ltd. | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity |
| US6063786A (en) * | 1997-11-12 | 2000-05-16 | Darwin Discovery, Ltd. | Heterocyclic compounds having MMP and TNF inhibitory activity |
| KR20010032319A (ko) | 1997-11-21 | 2001-04-16 | 로렌스 티. 마이젠헬더 | 매트릭스 메탈로프로테이나제 억제제로서 β-술포닐히드록스아민산의 α-히드록시, -아미노 및 -플루오로유도체 |
| JP2002501943A (ja) * | 1998-01-30 | 2002-01-22 | ダーウィン・ディスカバリー・リミテッド | ヒドロキサム酸およびカルボン酸誘導体 |
| DE69939190D1 (de) | 1998-06-18 | 2008-09-04 | Hoffmann La Roche | Verfahren für Arylalkylsulfid |
| GB9916562D0 (en) | 1999-07-14 | 1999-09-15 | Pharmacia & Upjohn Spa | 3-Arylsulfonyl-2-(substituted-methyl) propanoic acid derivatives as matrix metalloproteinase inhibitora |
| US6620823B2 (en) | 2000-07-11 | 2003-09-16 | Bristol-Myers Squibb Pharme Company | Lactam metalloprotease inhibitors |
| GB0017435D0 (en) * | 2000-07-14 | 2000-08-30 | Pharmacia & Upjohn Spa | 3-arylsulfonyl-2-hydroxy-2-methylpropanoic acid derivatives |
| PE20030701A1 (es) | 2001-12-20 | 2003-08-21 | Schering Corp | Compuestos para el tratamiento de trastornos inflamatorios |
| ATE457716T1 (de) | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
| CA2632030A1 (en) | 2005-12-15 | 2007-06-21 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| CA2657247A1 (en) | 2006-07-28 | 2008-01-31 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| WO2008039645A1 (en) | 2006-09-25 | 2008-04-03 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| CA2704684A1 (en) * | 2007-11-07 | 2009-05-14 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| CA2730037A1 (en) | 2008-07-10 | 2010-01-14 | Boehringer Ingelheim International Gmbh | Sulfone compounds which modulate the cb2 receptor |
| KR20110063485A (ko) | 2008-09-25 | 2011-06-10 | 베링거 인겔하임 인터내셔날 게엠베하 | Ｃｂ2 수용체를 선택적으로 조절하는 설포닐 화합물 |
| US8299103B2 (en) | 2009-06-15 | 2012-10-30 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
| JP5756800B2 (ja) | 2009-06-16 | 2015-07-29 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｂ２受容体を調節するアゼチジン２−カルボキサミド誘導体 |
| WO2011037795A1 (en) * | 2009-09-22 | 2011-03-31 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the cb2 receptor |
| WO2011088015A1 (en) | 2010-01-15 | 2011-07-21 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
| JP5746228B2 (ja) | 2010-03-05 | 2015-07-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｂ２受容体を選択的に調節するテトラゾール化合物 |
| US8846936B2 (en) | 2010-07-22 | 2014-09-30 | Boehringer Ingelheim International Gmbh | Sulfonyl compounds which modulate the CB2 receptor |
| EP2803668A1 (en) | 2013-05-17 | 2014-11-19 | Boehringer Ingelheim International Gmbh | Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB689608A (en) * | 1950-04-13 | 1953-04-01 | Basf Ag | Improvements in the production of gamma-sulphonyl carboxylic acids |
| US2659752A (en) * | 1951-08-09 | 1953-11-17 | Goodrich Co B F | Method for preparing beta-(arylsulfonyl) carboxylic acids and salts thereof |
| GB8827305D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
| EP0634998B1 (en) * | 1992-04-07 | 1997-03-19 | British Biotech Pharmaceuticals Limited | Hydroxamic acid based collagenase and cytokine inhibitors |
| DE4233099A1 (de) * | 1992-10-01 | 1994-04-07 | Hoechst Ag | Verfahren zur stereoselektiven Synthese von 3-substituierten 2-Thiomethylpropionsäuren |
| DE4233100A1 (de) * | 1992-10-01 | 1994-04-07 | Hoechst Ag | Verfahren zur stereoselektiven Synthese von 3-substituierten 2-Sulfonylmethylpropionsäuren sowie Zwischenprodukte |
| GB9223904D0 (en) * | 1992-11-13 | 1993-01-06 | British Bio Technology | Inhibition of cytokine production |
| EP0640594A1 (en) * | 1993-08-23 | 1995-03-01 | Fujirebio Inc. | Hydantoin derivative as metalloprotease inhibitor |
| GB9320660D0 (en) * | 1993-10-07 | 1993-11-24 | British Bio Technology | Inhibition of cytokine production |
| ES2183905T3 (es) * | 1995-12-20 | 2003-04-01 | Hoffmann La Roche | Inhibidores de metaloproteasa de matriz. |
| ES2217386T3 (es) * | 1996-01-02 | 2004-11-01 | Aventis Pharmaceuticals Inc. | Compuestos de acido(aril, heteroaril, arilmetil o heteroarilmetil) hidroxamico sustituido. |
| TW448172B (en) * | 1996-03-08 | 2001-08-01 | Pharmacia & Upjohn Co Llc | Novel hydroxamic acid derivatives useful for the treatment of diseases related to connective tissue degradation |
| KR20000048639A (ko) * | 1996-09-27 | 2000-07-25 | 로렌스 티. 마이젠헬더 | 매트릭스 메탈로프로테이나제 억제제인 베타-술포닐 히드록삼산 |
| WO1998039326A1 (en) | 1997-03-04 | 1998-09-11 | Monsanto Company | Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds |
-
1997
- 1997-09-19 KR KR1019990702581A patent/KR20000048639A/ko not_active Ceased
- 1997-09-19 HU HU0000145A patent/HUP0000145A3/hu unknown
- 1997-09-19 US US09/269,185 patent/US6235928B1/en not_active Expired - Fee Related
- 1997-09-19 US US08/934,408 patent/US5847153A/en not_active Expired - Fee Related
- 1997-09-19 AT AT97945207T patent/ATE289590T1/de not_active IP Right Cessation
- 1997-09-19 BR BR9712134-7A patent/BR9712134A/pt active Search and Examination
- 1997-09-19 CZ CZ99923A patent/CZ92399A3/cs unknown
- 1997-09-19 IL IL12890097A patent/IL128900A0/xx unknown
- 1997-09-19 JP JP51570298A patent/JP2001516338A/ja not_active Withdrawn
- 1997-09-19 PL PL97332509A patent/PL332509A1/xx unknown
- 1997-09-19 NZ NZ334729A patent/NZ334729A/xx unknown
- 1997-09-19 AU AU46459/97A patent/AU726799B2/en not_active Ceased
- 1997-09-19 EP EP97945207A patent/EP0929519B1/en not_active Expired - Lifetime
- 1997-09-19 WO PCT/US1997/016348 patent/WO1998013340A1/en not_active Ceased
- 1997-09-19 ID IDW990118A patent/ID21897A/id unknown
- 1997-09-19 EA EA199900332A patent/EA001460B1/ru not_active IP Right Cessation
- 1997-09-19 UA UA99042348A patent/UA48262C2/uk unknown
- 1997-09-19 ES ES97945207T patent/ES2236829T3/es not_active Expired - Lifetime
- 1997-09-19 CA CA002266368A patent/CA2266368A1/en not_active Abandoned
- 1997-09-19 DE DE69732571T patent/DE69732571T2/de not_active Expired - Fee Related
- 1997-09-19 CN CNB971979227A patent/CN1158254C/zh not_active Expired - Fee Related
-
1999
- 1999-03-26 NO NO19991494A patent/NO312893B1/no unknown