JP2001502170A5 - - Google Patents

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Publication number
JP2001502170A5
JP2001502170A5 JP1998516242A JP51624298A JP2001502170A5 JP 2001502170 A5 JP2001502170 A5 JP 2001502170A5 JP 1998516242 A JP1998516242 A JP 1998516242A JP 51624298 A JP51624298 A JP 51624298A JP 2001502170 A5 JP2001502170 A5 JP 2001502170A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998516242A
Other languages
English (en)
Japanese (ja)
Other versions
JP4005637B2 (ja
JP2001502170A (ja
Filing date
Publication date
Priority claimed from EP96115873A external-priority patent/EP0834569A1/en
Application filed filed Critical
Publication of JP2001502170A publication Critical patent/JP2001502170A/ja
Publication of JP2001502170A5 publication Critical patent/JP2001502170A5/ja
Application granted granted Critical
Publication of JP4005637B2 publication Critical patent/JP4005637B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP51624298A 1996-10-03 1997-10-01 カルボキシドテルムス ヒドロゲノホルマンス由来の熱安定dnaポリメラーゼ Expired - Fee Related JP4005637B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96115873A EP0834569A1 (en) 1996-10-03 1996-10-03 Thermostable DNA polymerase from carboxydothermus hydrogenoformans
EP96115873.0 1996-10-03
PCT/EP1997/005391 WO1998014589A1 (en) 1996-10-03 1997-10-01 Thermostable dna polymerase from carboxydothermus hydrogenoformans

Publications (3)

Publication Number Publication Date
JP2001502170A JP2001502170A (ja) 2001-02-20
JP2001502170A5 true JP2001502170A5 (enExample) 2005-05-12
JP4005637B2 JP4005637B2 (ja) 2007-11-07

Family

ID=8223262

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51624298A Expired - Fee Related JP4005637B2 (ja) 1996-10-03 1997-10-01 カルボキシドテルムス ヒドロゲノホルマンス由来の熱安定dnaポリメラーゼ

Country Status (12)

Country Link
US (1) US6468775B1 (enExample)
EP (2) EP0834569A1 (enExample)
JP (1) JP4005637B2 (enExample)
AT (1) ATE357527T1 (enExample)
AU (1) AU717009B2 (enExample)
CA (1) CA2268014C (enExample)
DE (1) DE69737502T2 (enExample)
IL (1) IL129085A (enExample)
NO (1) NO323846B1 (enExample)
NZ (1) NZ334652A (enExample)
RU (1) RU2197524C2 (enExample)
WO (1) WO1998014589A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0921196A1 (en) * 1997-12-02 1999-06-09 Roche Diagnostics GmbH Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction
EP0922765B1 (en) * 1997-12-02 2005-11-23 Roche Diagnostics GmbH Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction
US20030228616A1 (en) * 1999-10-29 2003-12-11 Stratagene DNA polymerase mutants with reverse transcriptase activity
US20040009486A1 (en) * 1999-10-29 2004-01-15 Sorge Joseph A. Compositions and methods utilizing DNA polymerases
US20050123940A1 (en) * 1999-10-29 2005-06-09 Stratagene California Compositions and methods for synthesizing cDNA
WO2006033665A1 (en) 2004-03-16 2006-03-30 Inist Inc. Tat-based vaccine compositions and methods of making and using same
ATE427992T1 (de) * 2001-11-14 2009-04-15 Toyo Boseki Dna-synthesepromotoren, mit dna-polymerase assoziierte faktoren und nutzung davon
BRPI0408967B8 (pt) 2003-03-31 2021-07-27 Hoffmann La Roche kit e métodos para detecção de um ácido nucléico de vários membros do sorogrupo do vírus da encefalite japonesa em uma amostra biológica sob condições de hibridização rigorosas
US8962293B2 (en) 2006-10-18 2015-02-24 Roche Molecular Systems, Inc. DNA polymerases and related methods
ES2432863T3 (es) 2009-03-23 2013-12-05 Pin Pharma, Inc. Tratamiento del cáncer con polipéptidos inmunoestimuladores derivados de Tat del VIH
CN103025867B (zh) 2010-06-18 2015-05-20 霍夫曼-拉罗奇有限公司 具有增强的3’-错配辨别力的dna聚合酶
EP2582806B1 (en) 2010-06-18 2015-12-16 Roche Diagnostics GmbH Dna polymerases with increased 3'-mismatch discrimination
EP2582807B1 (en) 2010-06-18 2015-03-18 Roche Diagnostics GmbH Dna polymerases with increased 3'-mismatch discrimination
CA2802304C (en) 2010-06-18 2016-01-12 F.Hoffman-La Roche Ag Dna polymerases with increased 3'-mismatch discrimination
WO2011157436A1 (en) 2010-06-18 2011-12-22 Roche Diagnostics Gmbh Dna polymerases with increased 3'-mismatch discrimination
WO2011157432A1 (en) 2010-06-18 2011-12-22 Roche Diagnostics Gmbh Dna polymerases with increased 3'-mismatch discrimination
EP2582802B1 (en) 2010-06-18 2016-01-13 Roche Diagnostics GmbH Dna polymerases with increased 3'-mismatch discrimination
US8759062B2 (en) 2010-06-18 2014-06-24 Roche Molecular Systems, Inc. DNA polymerases with increased 3′- mismatch discrimination
EP2675897B1 (en) 2011-02-15 2016-05-11 Roche Diagnostics GmbH Dna polymerases with increased 3'-mismatch discrimination
EP2697372B1 (en) 2011-04-11 2015-12-16 Roche Diagnostics GmbH Dna polymerases with improved activity
US9090883B2 (en) 2011-07-28 2015-07-28 Roche Molecular Systems, Inc. DNA polymerases with improved activity
WO2013083262A1 (en) 2011-12-08 2013-06-13 Roche Diagnostics Gmbh Dna polymerases with improved activity
JP6144697B2 (ja) 2011-12-08 2017-06-07 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 改善された活性を有するdnaポリメラーゼ
ES2569723T3 (es) 2011-12-08 2016-05-12 F. Hoffmann-La Roche Ag Polimerasas de DNA con actividad mejorada
US9663556B2 (en) 2013-10-04 2017-05-30 Pin Pharma, Inc. Treatment of cancers with immunostimulatory HIV tat derivative polypeptides
WO2019180137A1 (en) 2018-03-21 2019-09-26 F. Hoffmann-La Roche Ag Dna polymerases for efficient and effective incorporation of methylated-dntps
CN112703248B (zh) 2018-09-13 2025-03-25 豪夫迈·罗氏有限公司 具有改良链置换能力的突变型dna聚合酶
CN111733145A (zh) * 2020-07-01 2020-10-02 济南国科医工科技发展有限公司 重组酶的纯化方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5374553A (en) * 1986-08-22 1994-12-20 Hoffmann-La Roche Inc. DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima
US5912155A (en) * 1994-09-30 1999-06-15 Life Technologies, Inc. Cloned DNA polymerases from Thermotoga neapolitana

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