JP2001502170A5 - - Google Patents
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- Publication number
- JP2001502170A5 JP2001502170A5 JP1998516242A JP51624298A JP2001502170A5 JP 2001502170 A5 JP2001502170 A5 JP 2001502170A5 JP 1998516242 A JP1998516242 A JP 1998516242A JP 51624298 A JP51624298 A JP 51624298A JP 2001502170 A5 JP2001502170 A5 JP 2001502170A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96115873.0 | 1996-10-03 | ||
| EP96115873A EP0834569A1 (en) | 1996-10-03 | 1996-10-03 | Thermostable DNA polymerase from carboxydothermus hydrogenoformans |
| PCT/EP1997/005391 WO1998014589A1 (en) | 1996-10-03 | 1997-10-01 | Thermostable dna polymerase from carboxydothermus hydrogenoformans |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001502170A JP2001502170A (ja) | 2001-02-20 |
| JP2001502170A5 true JP2001502170A5 (enExample) | 2005-05-12 |
| JP4005637B2 JP4005637B2 (ja) | 2007-11-07 |
Family
ID=8223262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51624298A Expired - Fee Related JP4005637B2 (ja) | 1996-10-03 | 1997-10-01 | カルボキシドテルムス ヒドロゲノホルマンス由来の熱安定ｄｎａポリメラーゼ |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6468775B1 (enExample) |
| EP (2) | EP0834569A1 (enExample) |
| JP (1) | JP4005637B2 (enExample) |
| AT (1) | ATE357527T1 (enExample) |
| AU (1) | AU717009B2 (enExample) |
| CA (1) | CA2268014C (enExample) |
| DE (1) | DE69737502T2 (enExample) |
| IL (1) | IL129085A (enExample) |
| NO (1) | NO323846B1 (enExample) |
| NZ (1) | NZ334652A (enExample) |
| RU (1) | RU2197524C2 (enExample) |
| WO (1) | WO1998014589A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0922765B1 (en) * | 1997-12-02 | 2005-11-23 | Roche Diagnostics GmbH | Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction |
| EP0921196A1 (en) * | 1997-12-02 | 1999-06-09 | Roche Diagnostics GmbH | Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction |
| US20030228616A1 (en) * | 1999-10-29 | 2003-12-11 | Stratagene | DNA polymerase mutants with reverse transcriptase activity |
| US20050123940A1 (en) * | 1999-10-29 | 2005-06-09 | Stratagene California | Compositions and methods for synthesizing cDNA |
| US20040009486A1 (en) * | 1999-10-29 | 2004-01-15 | Sorge Joseph A. | Compositions and methods utilizing DNA polymerases |
| ATE427992T1 (de) * | 2001-11-14 | 2009-04-15 | Toyo Boseki | Dna-synthesepromotoren, mit dna-polymerase assoziierte faktoren und nutzung davon |
| CA2520538C (en) | 2003-03-31 | 2014-04-29 | F. Hoffmann-La Roche Ag | Compositions and methods for detecting certain flaviviruses, including members of the japanese encephalitis virus serogroup |
| US7927580B2 (en) | 2004-03-16 | 2011-04-19 | Nanirx, Inc. | Tat-based immunomodulatory compositions and methods of their discovery and use |
| US8962293B2 (en) | 2006-10-18 | 2015-02-24 | Roche Molecular Systems, Inc. | DNA polymerases and related methods |
| DK2411043T3 (da) | 2009-03-23 | 2013-10-21 | Pin Pharma Inc | Behandling af cancer med immunostimulatorisk hiv tat derivat-polypeptider |
| EP2582808B1 (en) | 2010-06-18 | 2015-04-22 | Roche Diagniostics GmbH | Dna polymerases with increased 3'-mismatch discrimination |
| CN103025868B (zh) | 2010-06-18 | 2015-07-01 | 霍夫曼-拉罗奇有限公司 | 具有增强的3’-错配辨别力的dna聚合酶 |
| WO2011157434A1 (en) | 2010-06-18 | 2011-12-22 | Roche Diagnostics Gmbh | Dna polymerases with increased 3'-mismatch discrimination |
| CA2801997C (en) | 2010-06-18 | 2016-05-31 | F. Hoffmann-La Roche Ag | Dna polymerases with increased 3'-mismatch discrimination |
| WO2011157438A1 (en) | 2010-06-18 | 2011-12-22 | Roche Diagnostics Gmbh | Dna polymerases with increasesed 3'-mismatch discrimination |
| EP2582804B1 (en) | 2010-06-18 | 2015-02-25 | Roche Diagnostics GmbH | Dna polymerases with increased 3'-mismatch discrimination |
| CN103025867B (zh) | 2010-06-18 | 2015-05-20 | 霍夫曼-拉罗奇有限公司 | 具有增强的3’-错配辨别力的dna聚合酶 |
| CA2802302C (en) | 2010-06-18 | 2016-04-26 | F. Hoffman-La Roche Ag | Dna polymerases with increased 3'-mismatch discrimination |
| WO2012110061A1 (en) | 2011-02-15 | 2012-08-23 | Roche Diagnostics Gmbh | Dna polymerases with increased 3'-mismatch discrimination |
| US9017979B2 (en) | 2011-04-11 | 2015-04-28 | Roche Molecular Systems, Inc. | DNA polymerases with improved activity |
| EP2737061B1 (en) | 2011-07-28 | 2015-09-16 | Roche Diagnostics GmbH | Dna polymerases with improved activity |
| CN103987844B (zh) | 2011-12-08 | 2016-01-20 | 霍夫曼-拉罗奇有限公司 | 具有改进活性的dna聚合酶 |
| EP2788480B1 (en) | 2011-12-08 | 2019-01-16 | Roche Diagnostics GmbH | Dna polymerases with improved activity |
| CN103987843B (zh) | 2011-12-08 | 2015-12-23 | 霍夫曼-拉罗奇有限公司 | 具有改进活性的dna聚合酶 |
| US9663556B2 (en) | 2013-10-04 | 2017-05-30 | Pin Pharma, Inc. | Treatment of cancers with immunostimulatory HIV tat derivative polypeptides |
| CN111868238B (zh) | 2018-03-21 | 2024-06-11 | 豪夫迈·罗氏有限公司 | 用于甲基化-dNTPs的效率高的和有效参入的DNA聚合酶 |
| CN112703248B (zh) | 2018-09-13 | 2025-03-25 | 豪夫迈·罗氏有限公司 | 具有改良链置换能力的突变型dna聚合酶 |
| CN111733145A (zh) * | 2020-07-01 | 2020-10-02 | 济南国科医工科技发展有限公司 | 重组酶的纯化方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5374553A (en) * | 1986-08-22 | 1994-12-20 | Hoffmann-La Roche Inc. | DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima |
| US5912155A (en) * | 1994-09-30 | 1999-06-15 | Life Technologies, Inc. | Cloned DNA polymerases from Thermotoga neapolitana |
-
1996
- 1996-10-03 EP EP96115873A patent/EP0834569A1/en not_active Withdrawn
-
1997
- 1997-10-01 EP EP97913133A patent/EP0929680B1/en not_active Expired - Lifetime
- 1997-10-01 CA CA002268014A patent/CA2268014C/en not_active Expired - Fee Related
- 1997-10-01 JP JP51624298A patent/JP4005637B2/ja not_active Expired - Fee Related
- 1997-10-01 WO PCT/EP1997/005391 patent/WO1998014589A1/en not_active Ceased
- 1997-10-01 RU RU99109121/13A patent/RU2197524C2/ru not_active IP Right Cessation
- 1997-10-01 NZ NZ334652A patent/NZ334652A/xx not_active IP Right Cessation
- 1997-10-01 DE DE69737502T patent/DE69737502T2/de not_active Expired - Lifetime
- 1997-10-01 US US09/269,861 patent/US6468775B1/en not_active Expired - Lifetime
- 1997-10-01 AT AT97913133T patent/ATE357527T1/de active
- 1997-10-01 IL IL129085A patent/IL129085A/en not_active IP Right Cessation
- 1997-10-01 AU AU50495/98A patent/AU717009B2/en not_active Ceased
-
1999
- 1999-03-30 NO NO19991568A patent/NO323846B1/no not_active IP Right Cessation