JP2001502170A5 - - Google Patents

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Publication number
JP2001502170A5
JP2001502170A5 JP1998516242A JP51624298A JP2001502170A5 JP 2001502170 A5 JP2001502170 A5 JP 2001502170A5 JP 1998516242 A JP1998516242 A JP 1998516242A JP 51624298 A JP51624298 A JP 51624298A JP 2001502170 A5 JP2001502170 A5 JP 2001502170A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998516242A
Other languages
English (en)
Japanese (ja)
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JP2001502170A (ja
JP4005637B2 (ja
Filing date
Publication date
Priority claimed from EP96115873A external-priority patent/EP0834569A1/en
Application filed filed Critical
Publication of JP2001502170A publication Critical patent/JP2001502170A/ja
Publication of JP2001502170A5 publication Critical patent/JP2001502170A5/ja
Application granted granted Critical
Publication of JP4005637B2 publication Critical patent/JP4005637B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP51624298A 1996-10-03 1997-10-01 カルボキシドテルムス ヒドロゲノホルマンス由来の熱安定dnaポリメラーゼ Expired - Fee Related JP4005637B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96115873A EP0834569A1 (en) 1996-10-03 1996-10-03 Thermostable DNA polymerase from carboxydothermus hydrogenoformans
EP96115873.0 1996-10-03
PCT/EP1997/005391 WO1998014589A1 (en) 1996-10-03 1997-10-01 Thermostable dna polymerase from carboxydothermus hydrogenoformans

Publications (3)

Publication Number Publication Date
JP2001502170A JP2001502170A (ja) 2001-02-20
JP2001502170A5 true JP2001502170A5 (enExample) 2005-05-12
JP4005637B2 JP4005637B2 (ja) 2007-11-07

Family

ID=8223262

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51624298A Expired - Fee Related JP4005637B2 (ja) 1996-10-03 1997-10-01 カルボキシドテルムス ヒドロゲノホルマンス由来の熱安定dnaポリメラーゼ

Country Status (12)

Country Link
US (1) US6468775B1 (enExample)
EP (2) EP0834569A1 (enExample)
JP (1) JP4005637B2 (enExample)
AT (1) ATE357527T1 (enExample)
AU (1) AU717009B2 (enExample)
CA (1) CA2268014C (enExample)
DE (1) DE69737502T2 (enExample)
IL (1) IL129085A (enExample)
NO (1) NO323846B1 (enExample)
NZ (1) NZ334652A (enExample)
RU (1) RU2197524C2 (enExample)
WO (1) WO1998014589A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0922765B1 (en) * 1997-12-02 2005-11-23 Roche Diagnostics GmbH Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction
EP0921196A1 (en) * 1997-12-02 1999-06-09 Roche Diagnostics GmbH Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction
US20050123940A1 (en) * 1999-10-29 2005-06-09 Stratagene California Compositions and methods for synthesizing cDNA
US20030228616A1 (en) * 1999-10-29 2003-12-11 Stratagene DNA polymerase mutants with reverse transcriptase activity
US20040009486A1 (en) * 1999-10-29 2004-01-15 Sorge Joseph A. Compositions and methods utilizing DNA polymerases
DE60231901D1 (de) * 2001-11-14 2009-05-20 Toyo Boseki Dna-synthesepromotoren, mit dna-polymerase assoziierte faktoren und nutzung davon
KR20070121853A (ko) 2003-03-31 2007-12-27 에프. 호프만-라 로슈 아게 일본 뇌염 바이러스 혈청군의 구성원을 포함하는, 특정플라비바이러스 검출용 조성물 및 방법
WO2005090968A1 (en) 2004-03-16 2005-09-29 Inist Inc. Tat-based immunomodulatory compositions and methods of their discovery and use
US8962293B2 (en) 2006-10-18 2015-02-24 Roche Molecular Systems, Inc. DNA polymerases and related methods
AU2010230073B2 (en) 2009-03-23 2016-05-26 Pin Pharma, Inc. Treatment of cancer with immunostimulatory HIV Tat derivative polypeptides
US8722378B2 (en) 2010-06-18 2014-05-13 Roche Molecular Systems, Inc. DNA polymerases with increased 3′-mismatch discrimination
CA2802000C (en) 2010-06-18 2016-08-16 F. Hoffmann-La Roche Ag Dna polymerases with increased 3'-mismatch discrimination
CN103025870B (zh) 2010-06-18 2015-07-01 霍夫曼-拉罗奇有限公司 具有增强的3’-错配辨别力的dna聚合酶
CN103025867B (zh) 2010-06-18 2015-05-20 霍夫曼-拉罗奇有限公司 具有增强的3’-错配辨别力的dna聚合酶
JP5876479B2 (ja) 2010-06-18 2016-03-02 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 増大した3’末端ミスマッチ識別を有するdnaポリメラーゼ
ES2536252T3 (es) 2010-06-18 2015-05-21 F. Hoffmann-La Roche Ag ADN polimerasas con diferenciación de desapareamientos 3' aumentada
JP5926248B2 (ja) 2010-06-18 2016-05-25 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 増大した3’末端ミスマッチ識別能を有するdnaポリメラーゼ
JP5841136B2 (ja) 2010-06-18 2016-01-13 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 増大した3’末端ミスマッチ識別能を有するdnaポリメラーゼ
EP2675897B1 (en) 2011-02-15 2016-05-11 Roche Diagnostics GmbH Dna polymerases with increased 3'-mismatch discrimination
CA2831180C (en) 2011-04-11 2017-02-14 Keith Bauer Dna polymerases with improved activity
JP6378085B2 (ja) 2011-07-28 2018-08-22 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 改善された活性を有するdnaポリメラーゼ
EP2788479B1 (en) 2011-12-08 2016-02-10 Roche Diagnostics GmbH Dna polymerases with improved activity
WO2013083262A1 (en) 2011-12-08 2013-06-13 Roche Diagnostics Gmbh Dna polymerases with improved activity
CN103987843B (zh) 2011-12-08 2015-12-23 霍夫曼-拉罗奇有限公司 具有改进活性的dna聚合酶
EP3052127A1 (en) 2013-10-04 2016-08-10 PIN Pharma, Inc. Immunostimulatory hiv tat derivative polypeptides for use in cancer treatment
US12043851B2 (en) 2018-03-21 2024-07-23 Roche Molecular Systems, Inc. DNA polymerases for efficient and effective incorporation of methylated-dNTPS
JP7504872B2 (ja) 2018-09-13 2024-06-24 エフ. ホフマン-ラ ロシュ アーゲー 改善されたストランド置換能力を有する変異体dnaポリメラーゼ
CN111733145A (zh) * 2020-07-01 2020-10-02 济南国科医工科技发展有限公司 重组酶的纯化方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5374553A (en) * 1986-08-22 1994-12-20 Hoffmann-La Roche Inc. DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima
US5912155A (en) * 1994-09-30 1999-06-15 Life Technologies, Inc. Cloned DNA polymerases from Thermotoga neapolitana

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