NZ334652A - Thermostable DNA polymerase from Carboxydothermus hydrogenoformans - Google Patents
Thermostable DNA polymerase from Carboxydothermus hydrogenoformansInfo
- Publication number
- NZ334652A NZ334652A NZ334652A NZ33465297A NZ334652A NZ 334652 A NZ334652 A NZ 334652A NZ 334652 A NZ334652 A NZ 334652A NZ 33465297 A NZ33465297 A NZ 33465297A NZ 334652 A NZ334652 A NZ 334652A
- Authority
- NZ
- New Zealand
- Prior art keywords
- polymerase
- reverse transcriptase
- dna polymerase
- carboxydothermus hydrogenoformans
- thermostable dna
- Prior art date
Links
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 title abstract 3
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 title abstract 3
- 241000620137 Carboxydothermus hydrogenoformans Species 0.000 title abstract 2
- 230000000694 effects Effects 0.000 abstract 4
- 102100034343 Integrase Human genes 0.000 abstract 3
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 abstract 3
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 abstract 2
- 230000001419 dependent effect Effects 0.000 abstract 2
- 229910001425 magnesium ion Inorganic materials 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 108060002716 Exonuclease Proteins 0.000 abstract 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 abstract 1
- 102100040853 PRKC apoptosis WT1 regulator protein Human genes 0.000 abstract 1
- 101710162991 PRKC apoptosis WT1 regulator protein Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 102000013165 exonuclease Human genes 0.000 abstract 1
- 229910052748 manganese Inorganic materials 0.000 abstract 1
- 239000011572 manganese Substances 0.000 abstract 1
- 229910001437 manganese ion Inorganic materials 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96115873A EP0834569A1 (en) | 1996-10-03 | 1996-10-03 | Thermostable DNA polymerase from carboxydothermus hydrogenoformans |
| PCT/EP1997/005391 WO1998014589A1 (en) | 1996-10-03 | 1997-10-01 | Thermostable dna polymerase from carboxydothermus hydrogenoformans |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ334652A true NZ334652A (en) | 2000-03-27 |
Family
ID=8223262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ334652A NZ334652A (en) | 1996-10-03 | 1997-10-01 | Thermostable DNA polymerase from Carboxydothermus hydrogenoformans |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6468775B1 (enExample) |
| EP (2) | EP0834569A1 (enExample) |
| JP (1) | JP4005637B2 (enExample) |
| AT (1) | ATE357527T1 (enExample) |
| AU (1) | AU717009B2 (enExample) |
| CA (1) | CA2268014C (enExample) |
| DE (1) | DE69737502T2 (enExample) |
| IL (1) | IL129085A (enExample) |
| NO (1) | NO323846B1 (enExample) |
| NZ (1) | NZ334652A (enExample) |
| RU (1) | RU2197524C2 (enExample) |
| WO (1) | WO1998014589A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0921196A1 (en) * | 1997-12-02 | 1999-06-09 | Roche Diagnostics GmbH | Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction |
| EP0922765B1 (en) * | 1997-12-02 | 2005-11-23 | Roche Diagnostics GmbH | Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction |
| US20040009486A1 (en) * | 1999-10-29 | 2004-01-15 | Sorge Joseph A. | Compositions and methods utilizing DNA polymerases |
| US20030228616A1 (en) * | 1999-10-29 | 2003-12-11 | Stratagene | DNA polymerase mutants with reverse transcriptase activity |
| US20050123940A1 (en) * | 1999-10-29 | 2005-06-09 | Stratagene California | Compositions and methods for synthesizing cDNA |
| EP1452593B1 (en) * | 2001-11-14 | 2009-04-08 | Toyo Boseki Kabushiki Kaisha | Dna synthesis promoters, dna polymerase-associated factors and utilization thereof |
| AU2004230569B2 (en) | 2003-03-31 | 2007-12-06 | F. Hoffmann-La Roche Ag | Compositions and methods for detecting certain flaviviruses, including members of the Japanese encephalitis virus serogroup |
| US20050208482A1 (en) | 2004-03-16 | 2005-09-22 | Cohen David I | Tat-based immunomodulatory compositions and methods for their discovery and use |
| US8962293B2 (en) | 2006-10-18 | 2015-02-24 | Roche Molecular Systems, Inc. | DNA polymerases and related methods |
| JP5692933B2 (ja) | 2009-03-23 | 2015-04-01 | ナニアールエックス セラピューティックス インコーポレイテッド | 免疫刺激ＨＩＶＴａｔ誘導体ポリペプチドによる腫瘍治療 |
| EP2582803B1 (en) | 2010-06-18 | 2015-02-25 | Roche Diagnostics GmbH | Dna polymerases with increased 3'-mismatch discrimination |
| WO2011157436A1 (en) | 2010-06-18 | 2011-12-22 | Roche Diagnostics Gmbh | Dna polymerases with increased 3'-mismatch discrimination |
| CN103003418B (zh) | 2010-06-18 | 2015-08-26 | 霍夫曼-拉罗奇有限公司 | 具有增强的3’-错配辨别力的dna聚合酶 |
| ES2536252T3 (es) | 2010-06-18 | 2015-05-21 | F. Hoffmann-La Roche Ag | ADN polimerasas con diferenciación de desapareamientos 3' aumentada |
| CN103025869B (zh) | 2010-06-18 | 2015-07-01 | 霍夫曼-拉罗奇有限公司 | 具有增强的3’-错配辨别力的dna聚合酶 |
| EP2582806B1 (en) | 2010-06-18 | 2015-12-16 | Roche Diagnostics GmbH | Dna polymerases with increased 3'-mismatch discrimination |
| WO2011157434A1 (en) | 2010-06-18 | 2011-12-22 | Roche Diagnostics Gmbh | Dna polymerases with increased 3'-mismatch discrimination |
| ES2564692T3 (es) | 2010-06-18 | 2016-03-28 | F. Hoffmann-La Roche Ag | ADN polimerasas con discriminación incrementada de no correspondencia 3' |
| EP2675897B1 (en) | 2011-02-15 | 2016-05-11 | Roche Diagnostics GmbH | Dna polymerases with increased 3'-mismatch discrimination |
| ES2561885T3 (es) | 2011-04-11 | 2016-03-01 | F. Hoffmann-La Roche Ag | ADN polimerasas de actividad mejorada |
| CA2839964C (en) | 2011-07-28 | 2019-03-12 | F. Hoffmann-La Roche Ag | Dna polymerases with improved activity |
| JP6144697B2 (ja) | 2011-12-08 | 2017-06-07 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 改善された活性を有するｄｎａポリメラーゼ |
| EP2788480B1 (en) | 2011-12-08 | 2019-01-16 | Roche Diagnostics GmbH | Dna polymerases with improved activity |
| WO2013083263A1 (en) | 2011-12-08 | 2013-06-13 | Roche Diagnostics Gmbh | Dna polymerases with improved activity |
| WO2015051245A1 (en) | 2013-10-04 | 2015-04-09 | Pin Pharma, Inc. | Immunostimulatory hiv tat derivative polypeptides for use in cancer treatment |
| ES2969883T3 (es) | 2018-03-21 | 2024-05-23 | Hoffmann La Roche | ADN polimerasas para la incorporación eficiente y eficaz de dNTP metilados |
| JP7504872B2 (ja) | 2018-09-13 | 2024-06-24 | エフ． ホフマン－ラ ロシュ アーゲー | 改善されたストランド置換能力を有する変異体ｄｎａポリメラーゼ |
| CN111733145A (zh) * | 2020-07-01 | 2020-10-02 | 济南国科医工科技发展有限公司 | 重组酶的纯化方法 |
| WO2026153862A1 (en) | 2025-01-14 | 2026-07-23 | F. Hoffmann-La Roche Ag | Dna polymerases with improved activity |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5374553A (en) * | 1986-08-22 | 1994-12-20 | Hoffmann-La Roche Inc. | DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima |
| US5912155A (en) * | 1994-09-30 | 1999-06-15 | Life Technologies, Inc. | Cloned DNA polymerases from Thermotoga neapolitana |
-
1996
- 1996-10-03 EP EP96115873A patent/EP0834569A1/en not_active Withdrawn
-
1997
- 1997-10-01 JP JP51624298A patent/JP4005637B2/ja not_active Expired - Fee Related
- 1997-10-01 DE DE69737502T patent/DE69737502T2/de not_active Expired - Lifetime
- 1997-10-01 NZ NZ334652A patent/NZ334652A/xx not_active IP Right Cessation
- 1997-10-01 AU AU50495/98A patent/AU717009B2/en not_active Ceased
- 1997-10-01 WO PCT/EP1997/005391 patent/WO1998014589A1/en not_active Ceased
- 1997-10-01 US US09/269,861 patent/US6468775B1/en not_active Expired - Lifetime
- 1997-10-01 RU RU99109121/13A patent/RU2197524C2/ru not_active IP Right Cessation
- 1997-10-01 IL IL129085A patent/IL129085A/en not_active IP Right Cessation
- 1997-10-01 CA CA002268014A patent/CA2268014C/en not_active Expired - Fee Related
- 1997-10-01 AT AT97913133T patent/ATE357527T1/de active
- 1997-10-01 EP EP97913133A patent/EP0929680B1/en not_active Expired - Lifetime
-
1999
- 1999-03-30 NO NO19991568A patent/NO323846B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO323846B1 (no) | 2007-07-09 |
| CA2268014C (en) | 2008-01-15 |
| NO991568L (no) | 1999-06-02 |
| IL129085A (en) | 2006-12-10 |
| US6468775B1 (en) | 2002-10-22 |
| EP0834569A1 (en) | 1998-04-08 |
| JP2001502170A (ja) | 2001-02-20 |
| EP0929680B1 (en) | 2007-03-21 |
| WO1998014589A1 (en) | 1998-04-09 |
| DE69737502D1 (en) | 2007-05-03 |
| DE69737502T2 (de) | 2007-10-31 |
| EP0929680A1 (en) | 1999-07-21 |
| JP4005637B2 (ja) | 2007-11-07 |
| RU2197524C2 (ru) | 2003-01-27 |
| AU5049598A (en) | 1998-04-24 |
| CA2268014A1 (en) | 1998-04-09 |
| ATE357527T1 (de) | 2007-04-15 |
| NO991568D0 (no) | 1999-03-30 |
| AU717009B2 (en) | 2000-03-16 |
| IL129085A0 (en) | 2000-02-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK72992D0 (da) | Enzym | |
| WO1995004162A3 (en) | Dna sequencing enzymes | |
| AU6361096A (en) | Derivatives of benzosulphonamides as inhibitors of the enzyme cyclooxygenase II | |
| GR3017935T3 (en) | Composition and methods for removing or preventing biofilm. | |
| AU5809494A (en) | An enzyme with endoglucanase activity | |
| AU7908598A (en) | Alkaline xyloglucanase | |
| AU4037789A (en) | Uses of viral enzymes | |
| CA2222744A1 (en) | Thermostable dna polymerases | |
| EP0198428A3 (en) | Cleaning and polishing compositions | |
| DE69304707D1 (de) | Verfahren zur modifizierung von alfa-olefincopolymeren | |
| DE69734669D1 (de) | Enzymatische cofaktor-regeneration unter verwendung von pyridin-nucleotid transhydrogenase | |
| ATE263245T1 (de) | Verbesserte mutanten von (2,5 dkg) reduktase a | |
| US6165768A (en) | Recombinant thermostable enzyme for converting maltose into trehalose | |
| EP0321266A3 (en) | Method for producing the foki restriction endonuclease and methylase | |
| ATE63338T1 (de) | Verfahren zur herstellung von 6hydroxynikotins|ure. | |
| AU3350089A (en) | Antihypertensive hyperimmune milk, production, composition, and use | |
| ES2058702T3 (es) | N-acil-l-prolin-acilasa preparada por via microbiologica, procedimiento para su obtencion y su empleo. | |
| NZ334654A (en) | A process for amplifying DNA using a thermostable DNA polymerase from Anaerocellum thermophilum characterised in that it works in the presence of magnesium ions and the absence of manganese ions | |
| NZ334653A (en) | Thermostable nucleic acid polymerase with 3'-5' proofreading exonuclease ability from Thermococcus gorgonarius | |
| AU5991099A (en) | Heteropolysaccharide produced by an agrobacterium radiobacter | |
| WO2000030623A3 (de) | Prolaktin-senkendes mittel | |
| BR9700840A (pt) | Mistura de polisocianato de baixa viscosidade | |
| KR910004811A (ko) | 이종 단백질을 이.콜라이 내에서 제조하기 위한 최적 발효방법 | |
| GB2341391B (en) | Cloning of UDP-galactose epimerase | |
| ATE417899T1 (de) | Enzymatische konservierung von wässrigen lacken |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) | ||
| EXPY | Patent expired |