|
US5869270A
(en)
|
1996-01-31 |
1999-02-09 |
Sunol Molecular Corporation |
Single chain MHC complexes and uses thereof
|
|
US6458354B1
(en)
|
1996-03-28 |
2002-10-01 |
The Johns Hopkins University |
Molecular complexes which modify immune responses
|
|
JPH11507843A
(ja)
|
1996-03-28 |
1999-07-13 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
タンパク質の可溶性二価および多価ヘテロ二量体類縁体
|
|
US6211342B1
(en)
*
|
1996-07-18 |
2001-04-03 |
Children's Hospital Medical Center |
Multivalent MHC complex peptide fusion protein complex for stimulating specific T cell function
|
|
US6268411B1
(en)
|
1997-09-11 |
2001-07-31 |
The Johns Hopkins University |
Use of multivalent chimeric peptide-loaded, MHC/ig molecules to detect, activate or suppress antigen-specific T cell-dependent immune responses
|
|
US20030007978A1
(en)
*
|
1997-09-16 |
2003-01-09 |
Burrows Gregory G. |
Recombinant MHC molecules useful for manipulation of antigen-specific T-cells
|
|
EP1017721B1
(en)
*
|
1997-09-16 |
2009-02-25 |
Oregon Health and Science University |
Recombinant mhc molecules useful for manipulation of antigen-specific t-cells
|
|
US6232445B1
(en)
*
|
1997-10-29 |
2001-05-15 |
Sunol Molecular Corporation |
Soluble MHC complexes and methods of use thereof
|
|
GB2339782A
(en)
*
|
1998-06-05 |
2000-02-09 |
Philip Michael Savage |
Chimeric protein complexes comprising HLA class I antigens
|
|
KR20010103788A
(ko)
*
|
1999-03-03 |
2001-11-23 |
멕코나시 에블린 에이치. |
백신 및 유전자요법 조성물 및 이들의 제조 및 사용방법
|
|
JP4673978B2
(ja)
*
|
1999-04-16 |
2011-04-20 |
オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド |
濃縮された抗原特異的ｔ細胞、ならびに関係する治療および予防の組成物および方法
|
|
DE60041183D1
(de)
*
|
1999-05-06 |
2009-02-05 |
Univ Wake Forest |
Zusammensetzungen und methoden zur identifikation von antigenen, die eine immunantwort hervorrufen
|
|
FR2796953B1
(fr)
*
|
1999-07-29 |
2003-10-10 |
Centre Nat Rech Scient |
Proteines recombinantes, et complexes moleculaires derives de ces proteines, analogues a des molecules impliquees dans les reponses immunitaires
|
|
US6995237B1
(en)
*
|
1999-10-27 |
2006-02-07 |
Cel-Sci Corporation |
Preparation and composition of peptides useful for treatment of autoimmune and transplant related graft versus host conditions
|
|
US6316256B1
(en)
*
|
2000-01-03 |
2001-11-13 |
Tr Associates, L.L.C. |
Method for protein transfer
|
|
US7572631B2
(en)
|
2000-02-24 |
2009-08-11 |
Invitrogen Corporation |
Activation and expansion of T cells
|
|
US7541184B2
(en)
*
|
2000-02-24 |
2009-06-02 |
Invitrogen Corporation |
Activation and expansion of cells
|
|
US20040191260A1
(en)
|
2003-03-26 |
2004-09-30 |
Technion Research & Development Foundation Ltd. |
Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof
|
|
JP2004503213A
(ja)
*
|
2000-03-27 |
2004-02-05 |
テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド |
１本鎖クラスｉ主要組織適合性複合体、それをコードする構築物およびそれを生成する方法
|
|
US20020006397A1
(en)
*
|
2000-04-28 |
2002-01-17 |
Roberts Bruce L. |
In VIVO loading of MHC
|
|
JP2004501364A
(ja)
*
|
2000-05-25 |
2004-01-15 |
スノル・モレキュラー・コーポレーション |
Ｔ−細胞レセプター相互作用のモジュレーション
|
|
GB0110547D0
(en)
*
|
2001-04-30 |
2001-06-20 |
Avidex Ltd |
Method
|
|
US6811785B2
(en)
*
|
2001-05-07 |
2004-11-02 |
Mount Sinai School Of Medicine Of New York University |
Multivalent MHC class II—peptide chimeras
|
|
DE60228504D1
(de)
|
2001-06-05 |
2008-10-02 |
Altor Bioscience Corp |
P53 bindende t-zellrezeptormoleküle und deren verwendungen
|
|
US20030017134A1
(en)
*
|
2001-06-19 |
2003-01-23 |
Technion Research And Development Foundation Ltd. |
Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer
|
|
US8022190B2
(en)
*
|
2001-06-19 |
2011-09-20 |
Technion Research & Development Foundation Ltd. |
Immuno-molecules containing viral proteins, compositions thereof and methods of using
|
|
JPWO2003029475A1
(ja)
*
|
2001-09-28 |
2005-01-20 |
株式会社ディナベック研究所 |
エピトープ結合β２ｍをコードする哺乳動物細胞感染性ウイルスベクターおよびその利用
|
|
WO2003059952A1
(en)
*
|
2002-01-18 |
2003-07-24 |
Inovio As |
Bispecific antibody dna constructs for intramuscular administration
|
|
US20030199024A1
(en)
*
|
2002-04-19 |
2003-10-23 |
Hansen Ted H. |
Single chain trimers of class I MHC molecules
|
|
ES2422193T3
(es)
*
|
2002-06-28 |
2013-09-09 |
Life Technologies Corp |
Métodos para restaurar el repertorio inmune en pacientes con defectos inmunológicos relacionados con la autoinmunidad y trasplante de órganos o de células madre hematopoyéticas
|
|
US20040175373A1
(en)
*
|
2002-06-28 |
2004-09-09 |
Xcyte Therapies, Inc. |
Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
US20050084967A1
(en)
|
2002-06-28 |
2005-04-21 |
Xcyte Therapies, Inc. |
Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
EP1551449B1
(en)
*
|
2002-07-12 |
2010-10-06 |
The Johns Hopkins University |
Reagents and methods for engaging unique clonotypic lymphocyte receptors
|
|
AU2003273219A1
(en)
*
|
2002-07-12 |
2004-02-02 |
Dana-Farber Cancer Institute, Inc. |
Novel compositions and methods for the generation of mhc class ii compounds by peptide exchange
|
|
WO2004031380A1
(ja)
*
|
2002-10-01 |
2004-04-15 |
Dnavec Research Inc. |
TAP活性の阻害により MHC class I による外来エピトープの提示を増強する方法
|
|
US7927840B2
(en)
*
|
2006-09-11 |
2011-04-19 |
Gen Probe Incorporated |
Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region
|
|
EP3241915B1
(en)
*
|
2002-10-16 |
2021-06-23 |
Gen-Probe Incorporated |
Compositions and methods for detecting west nile virus
|
|
ES2396231T3
(es)
|
2003-05-21 |
2013-02-20 |
Biotech Tools S.A. |
Complejo peptídico
|
|
JP2008500006A
(ja)
*
|
2003-05-21 |
2008-01-10 |
バイオテック トゥールス ソシエテ アノニム |
ペプチド複合体
|
|
AU2004288157B2
(en)
*
|
2003-09-05 |
2011-03-17 |
Oregon Health & Science University |
Monomeric recombinant MHC molecules useful for manipulation of antigen-specific T cells
|
|
CN1901839A
(zh)
|
2003-11-10 |
2007-01-24 |
阿尔特生物科学公司 |
可溶性tcr分子及其用途
|
|
US20050227351A1
(en)
*
|
2004-04-08 |
2005-10-13 |
Awdalla Essam T |
Methods and compound protein molecules used for inducing cytotoxic cell-mediated immune response in a mammal against a pathogenic cell
|
|
DE102004019803A1
(de)
*
|
2004-04-23 |
2005-11-10 |
Imusyn Gmbh & Co.Kg |
Verfahren zur Herstellung löslicher MHC-Proteine
|
|
GB2422834B8
(en)
*
|
2005-02-04 |
2007-01-04 |
Proimmune Ltd |
MHC oligomer and method of making the same
|
|
WO2007085266A1
(en)
*
|
2006-01-30 |
2007-08-02 |
Dako Denmark A/S |
High-speed quantification of antigen specific t-cells in whole blood by flow cytometry
|
|
US8518697B2
(en)
*
|
2006-04-04 |
2013-08-27 |
Washington University |
Single chain trimers and uses therefor
|
|
EP2024507B1
(en)
*
|
2006-05-19 |
2015-07-22 |
Technion Research and Development Foundation Ltd. |
Fusion proteins, uses thereof and processes for producing same
|
|
EP2155782A2
(en)
|
2007-03-26 |
2010-02-24 |
Dako Denmark A/S |
Mhc peptide complexes and uses thereof in infectious diseases
|
|
EP3023436A1
(en)
|
2007-07-03 |
2016-05-25 |
Dako Denmark A/S |
Improved methods for generation, labeling and use of mhc multimers
|
|
EP2197908A2
(en)
|
2007-09-27 |
2010-06-23 |
Dako Denmark A/S |
Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics
|
|
DK2254592T3
(da)
|
2008-02-28 |
2019-09-09 |
Dako Denmark As |
MHC-multimerer til Borrelia-diagnostik og sygdom
|
|
WO2010009735A2
(en)
*
|
2008-07-23 |
2010-01-28 |
Dako Denmark A/S |
Combinatorial analysis and repair
|
|
GB0817244D0
(en)
*
|
2008-09-20 |
2008-10-29 |
Univ Cardiff |
Use of a protein kinase inhibitor to detect immune cells, such as T cells
|
|
US11992518B2
(en)
|
2008-10-02 |
2024-05-28 |
Agilent Technologies, Inc. |
Molecular vaccines for infectious disease
|
|
US10369204B2
(en)
|
2008-10-02 |
2019-08-06 |
Dako Denmark A/S |
Molecular vaccines for infectious disease
|
|
US20110124019A1
(en)
*
|
2009-11-25 |
2011-05-26 |
The Charlotte-Mecklenburg Hospital Authority |
Method of using carbonic anhydrase to detect hemolysis
|
|
JP5665021B2
(ja)
*
|
2010-03-08 |
2015-02-04 |
国立大学法人東京農工大学 |
融合ｍｈｃ分子連結磁気微粒子、抗原ペプチドのスクリーニング方法、組換えベクター、及び磁性細菌の形質転換体
|
|
WO2011147894A1
(en)
|
2010-05-25 |
2011-12-01 |
Forschungsverbund Berlin E.V. |
Chimeric mhc class ii proteinpeptide
|
|
GB201013767D0
(en)
*
|
2010-08-17 |
2010-09-29 |
Isis Innovation |
Identification of ligands and their use
|
|
US20140134195A1
(en)
|
2011-04-20 |
2014-05-15 |
University Of Washington Through Its Center For Commercialization |
Beta-2 microglobulin-deficient cells
|
|
US8753309B2
(en)
|
2011-06-24 |
2014-06-17 |
The Invention Science Fund I, Llc |
Device, system, and method including micro-patterned cell treatment array
|
|
CA2865033C
(en)
|
2012-02-23 |
2021-11-02 |
Stage Cell Therapeutics Gmbh |
Chromatographic isolation of cells and other complex biological materials
|
|
CN105026422B
(zh)
|
2012-03-27 |
2019-09-27 |
西安大略大学 |
Sh2结构域变体
|
|
DK2838548T5
(en)
*
|
2012-04-17 |
2024-08-05 |
Univ Washington Through Its Center For Commercialization |
Hla class ii deficient cells, hla class i deficient cells capable of expressing hla class ii proteins, and uses thereof
|
|
JP6445427B2
(ja)
*
|
2012-05-08 |
2018-12-26 |
ウエスタン ユニバーシティ オブ ヘルス サイエンシズ |
ＣＤ４＋Ｔ細胞集団の抗原特異的な拡大のために標準化されたｅｘｖｉｖｏプラットフォーム
|
|
CN105121715B
(zh)
|
2012-12-11 |
2018-10-26 |
艾伯特叶史瓦大学爱因斯坦医学院 |
高通量受体:配体鉴定方法
|
|
WO2014141244A1
(en)
|
2013-03-12 |
2014-09-18 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Synthetic peptides for the treatment of autoimmune diseases
|
|
GB201313352D0
(en)
|
2013-07-26 |
2013-09-11 |
Isis Innovation |
Identification of peptide ligands
|
|
DK3480213T3
(da)
*
|
2014-06-18 |
2020-02-17 |
Albert Einstein College Medicine |
Syntac-polypeptider og anvendelser deraf
|
|
KR20170083534A
(ko)
|
2014-09-19 |
2017-07-18 |
리제너론 파마슈티칼스 인코포레이티드 |
키메라 항원 수용체
|
|
MA45489A
(fr)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
Procédés de culture de cellules, kits et appareil associés
|
|
JP7195141B2
(ja)
|
2015-10-22 |
2022-12-23 |
ジュノ セラピューティクス ゲーエムベーハー |
形質導入のための方法、キット、作用物質および装置
|
|
AU2017268348A1
(en)
|
2016-05-18 |
2018-10-25 |
Cue Biopharma, Inc. |
T-cell modulatory multimeric polypeptides and methods of use thereof
|
|
KR20190044029A
(ko)
|
2016-05-18 |
2019-04-29 |
알버트 아인슈타인 컬리지 오브 메디슨, 인크. |
변이체 pd-l1 폴리펩타이드, t-세포 조절 다량체 폴리펩타이드 및 이들의 사용 방법
|
|
WO2018046468A1
(en)
|
2016-09-06 |
2018-03-15 |
F. Hoffmann-La Roche Ag |
Mhc-bound peptide arrays and methods of use thereof
|
|
CN118453840A
(zh)
|
2017-03-15 |
2024-08-09 |
库尔生物制药有限公司 |
用于调节免疫应答的方法
|
|
ES3038614T3
(en)
|
2017-04-27 |
2025-10-14 |
Juno Therapeutics Inc |
Oligomeric particle reagents and methods of use thereof
|
|
WO2019139896A1
(en)
|
2018-01-09 |
2019-07-18 |
Cue Biopharma, Inc. |
Multimeric t-cell modulatory polypeptides and methods of use thereof
|
|
MX2021005013A
(es)
|
2018-10-31 |
2021-07-21 |
Juno Therapeutics Gmbh |
Métodos para la selección y estimulación de células y aparatos para los mismos.
|
|
WO2020127222A2
(en)
|
2018-12-17 |
2020-06-25 |
Immudex Aps |
Panel comprising borrelia mhc multimers
|
|
WO2020142750A2
(en)
*
|
2019-01-03 |
2020-07-09 |
Regents Of The University Of Minnesota |
Genetically modified cells, tissues, and organs for treating disease
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
TW202144388A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
|
TW202144389A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在多發性骨髓瘤中表現之新抗原及其用途
|
|
WO2021231376A2
(en)
|
2020-05-12 |
2021-11-18 |
Cue Biopharma, Inc. |
Multimeric t-cell modulatory polypeptides and methods of use thereof
|
|
WO2022009052A2
(en)
|
2020-07-06 |
2022-01-13 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
EP4211149A4
(en)
|
2020-09-09 |
2024-10-09 |
Cue Biopharma, Inc. |
MULTIMERIC POLYPEPTIDES MODULATING MHC CLASS II T CELLS FOR THE TREATMENT OF TYPE 1 DIABETES MELLITUS (T1D) AND METHODS OF USE THEREOF
|
|
UY39467A
(es)
|
2020-10-13 |
2022-04-29 |
Janssen Biotech Inc |
Inmunidad mediada por células t de bioingeniería, materiales y otros métodos para modular el grupo de diferenciación iv y / o viii
|