|
DK0804562T3
(da)
*
|
1994-07-12 |
2003-02-10 |
Human Genome Sciences Inc |
Bindevævsvækstfaktor-2
|
|
US7026299B2
(en)
*
|
1994-07-12 |
2006-04-11 |
Human Genome Sciences, Inc. |
Connective tissue growth factor-2
|
|
US6302875B1
(en)
|
1996-10-11 |
2001-10-16 |
Transvascular, Inc. |
Catheters and related devices for forming passageways between blood vessels or other anatomical structures
|
|
US6261281B1
(en)
|
1997-04-03 |
2001-07-17 |
Electrofect As |
Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
|
|
IL132103A0
(en)
*
|
1997-04-03 |
2001-03-19 |
Eletrofect As |
Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle
|
|
WO1999001158A1
(fr)
|
1997-06-30 |
1999-01-14 |
Rhone-Poulenc Rorer S.A. |
Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede
|
|
ATE290403T1
(de)
|
1997-06-30 |
2005-03-15 |
Roussy Inst Gustave |
Verbesserung der verabreichung der nukleinsäure in zellen der plurizellulären eukaryotischen organismen und kombination zur durchführung des verfahrens
|
|
US6219577B1
(en)
|
1998-04-14 |
2001-04-17 |
Global Vascular Concepts, Inc. |
Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues
|
|
AU3973599A
(en)
*
|
1998-05-08 |
1999-11-29 |
Genetronics, Inc. |
Electrically induced vessel vasodilation
|
|
US6027488A
(en)
*
|
1998-06-03 |
2000-02-22 |
Genetronics, Inc. |
Flow-through electroporation system for ex vivo gene therapy
|
|
US6800484B2
(en)
*
|
1998-06-24 |
2004-10-05 |
Genetronics, Inc. |
High efficiency transfection based on low electric field strength, long pulse length
|
|
US20040229363A1
(en)
*
|
1998-06-24 |
2004-11-18 |
Ed Nolan |
High efficiency transfection based on low electric field strength, long pulse length
|
|
EP1100576B1
(en)
*
|
1998-06-26 |
2007-08-15 |
Genetronics, Inc. |
Synergism of photodynamic and electropermeation effects on cell vitality as a novel cytotoxic agent
|
|
US6501990B1
(en)
|
1999-12-23 |
2002-12-31 |
Cardiac Pacemakers, Inc. |
Extendable and retractable lead having a snap-fit terminal connector
|
|
US6463334B1
(en)
|
1998-11-02 |
2002-10-08 |
Cardiac Pacemakers, Inc. |
Extendable and retractable lead
|
|
EP1128866A4
(en)
*
|
1998-11-12 |
2008-11-05 |
Ats Med Inc |
ELECTRICALLY MEDIATED ANGIOGENESIS
|
|
US6363938B2
(en)
*
|
1998-12-22 |
2002-04-02 |
Angiotrax, Inc. |
Methods and apparatus for perfusing tissue and/or stimulating revascularization and tissue growth
|
|
CA2368728A1
(en)
*
|
1999-03-25 |
2000-09-28 |
Genetronics, Inc. |
Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
|
|
US6702811B2
(en)
|
1999-04-05 |
2004-03-09 |
Medtronic, Inc. |
Ablation catheter assembly with radially decreasing helix and method of use
|
|
US6317615B1
(en)
|
1999-04-19 |
2001-11-13 |
Cardiac Pacemakers, Inc. |
Method and system for reducing arterial restenosis in the presence of an intravascular stent
|
|
WO2000067825A1
(en)
|
1999-05-07 |
2000-11-16 |
Microheart, Inc. |
Apparatus and method for delivering therapeutic and diagnostic agents
|
|
US7147633B2
(en)
|
1999-06-02 |
2006-12-12 |
Boston Scientific Scimed, Inc. |
Method and apparatus for treatment of atrial fibrillation
|
|
CA2377565A1
(en)
*
|
1999-06-25 |
2001-01-04 |
Genetronics, Inc. |
High efficiency transfection based on low electric field strength, long pulse length
|
|
DE60026313D1
(de)
*
|
1999-07-23 |
2006-04-27 |
Uutech Ltd |
Sensibilisierung von roten blutkörperchen gegenüber ultraschall durch einwirkung eines elektrischen feldes
|
|
US6326177B1
(en)
|
1999-08-04 |
2001-12-04 |
Eastern Virginia Medical School Of The Medical College Of Hampton Roads |
Method and apparatus for intracellular electro-manipulation
|
|
US7063838B1
(en)
*
|
1999-09-24 |
2006-06-20 |
Proteon Therapeutics Llc |
Methods for treating an artery or vein in a human subject
|
|
US7632494B2
(en)
*
|
1999-09-24 |
2009-12-15 |
Proteon Therapeutics, Inc. |
Methods for enlarging the diameter of a biological conduit in a human subject
|
|
US6587718B2
(en)
*
|
1999-10-08 |
2003-07-01 |
Scimed Life Systems, Inc. |
Iontophoretic delivery to heart tissue
|
|
US6329348B1
(en)
|
1999-11-08 |
2001-12-11 |
Cornell Research Foundation, Inc. |
Method of inducing angiogenesis
|
|
US20060052328A1
(en)
*
|
2000-07-11 |
2006-03-09 |
Human Genome Sciences, Inc. |
Connective tissue growth factor-2
|
|
EP1373299A4
(en)
*
|
2000-07-11 |
2005-01-19 |
Human Genome Sciences Inc |
Connective tissue GROWTH FACTOR-2
|
|
US8251986B2
(en)
|
2000-08-17 |
2012-08-28 |
Angiodynamics, Inc. |
Method of destroying tissue cells by eletroporation
|
|
US20090175790A1
(en)
*
|
2000-09-06 |
2009-07-09 |
The Johns Hopkins University |
Cardiac arrhythmia treatment methods and biological pacemaker
|
|
AU2001288807B2
(en)
*
|
2000-09-06 |
2007-07-19 |
Johns Hopkins University |
Cardiac arrhythmia treatment methods
|
|
DE10103288A1
(de)
*
|
2001-01-25 |
2002-08-01 |
Patrick Schauerte |
Gefäßschleuse zur intravaskulären Nervenstimulation und Flüssigkeitsinfusion
|
|
US20030170642A1
(en)
*
|
2001-03-12 |
2003-09-11 |
Irm, Llc |
Identification of cellular targets for biologically active molecules
|
|
US7294511B2
(en)
|
2001-03-22 |
2007-11-13 |
Chromos Molecular Systems, Inc. |
Methods for delivering nucleic acid molecules into cells and assessment thereof
|
|
US20030186390A1
(en)
*
|
2001-03-22 |
2003-10-02 |
De Jong Gary |
Methods for delivering nucleic acid molecules into cells and assessment thereof
|
|
US6936469B2
(en)
|
2001-03-22 |
2005-08-30 |
Chromos Molecular Systems Inc. |
Methods for delivering nucleic acid molecules into cells and assessment thereof
|
|
US6625486B2
(en)
*
|
2001-04-11 |
2003-09-23 |
Advanced Cardiovascular Systems, Inc. |
Method and apparatus for intracellular delivery of an agent
|
|
JP4279558B2
(ja)
*
|
2001-04-27 |
2009-06-17 |
ジョンズ・ホプキンス・ユニバーシティ |
生物学的ペースメーカー
|
|
US20020169480A1
(en)
*
|
2001-05-10 |
2002-11-14 |
Qingsheng Zhu |
Method and device for preventing plaque formation in coronary arteries
|
|
US7493162B2
(en)
*
|
2001-06-15 |
2009-02-17 |
Cardiac Pacemakers, Inc. |
Pulmonary vein stent for treating atrial fibrillation
|
|
WO2003013615A1
(en)
*
|
2001-08-07 |
2003-02-20 |
Malone Robert W |
Electroporative delivery of molecules to organs
|
|
US6994706B2
(en)
|
2001-08-13 |
2006-02-07 |
Minnesota Medical Physics, Llc |
Apparatus and method for treatment of benign prostatic hyperplasia
|
|
US20030170898A1
(en)
*
|
2001-12-04 |
2003-09-11 |
Gundersen Martin A. |
Method for intracellular modifications within living cells using pulsed electric fields
|
|
US20040219660A1
(en)
*
|
2001-12-14 |
2004-11-04 |
Dev Sukhendu B. |
Electroporation-mediated intravascular delivery
|
|
AU2003219805B2
(en)
*
|
2002-02-15 |
2009-06-04 |
Eisai Inc. |
Electroporation methods for introducing bioactive agents into cells
|
|
US7236821B2
(en)
*
|
2002-02-19 |
2007-06-26 |
Cardiac Pacemakers, Inc. |
Chronically-implanted device for sensing and therapy
|
|
US7245963B2
(en)
*
|
2002-03-07 |
2007-07-17 |
Advisys, Inc. |
Electrode assembly for constant-current electroporation and use
|
|
US8209006B2
(en)
*
|
2002-03-07 |
2012-06-26 |
Vgx Pharmaceuticals, Inc. |
Constant current electroporation device and methods of use
|
|
US8145316B2
(en)
|
2002-04-08 |
2012-03-27 |
Ardian, Inc. |
Methods and apparatus for renal neuromodulation
|
|
US8145317B2
(en)
|
2002-04-08 |
2012-03-27 |
Ardian, Inc. |
Methods for renal neuromodulation
|
|
US7620451B2
(en)
|
2005-12-29 |
2009-11-17 |
Ardian, Inc. |
Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
|
|
US9636174B2
(en)
|
2002-04-08 |
2017-05-02 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods for therapeutic renal neuromodulation
|
|
US8551069B2
(en)
|
2002-04-08 |
2013-10-08 |
Medtronic Adrian Luxembourg S.a.r.l. |
Methods and apparatus for treating contrast nephropathy
|
|
US6978174B2
(en)
|
2002-04-08 |
2005-12-20 |
Ardian, Inc. |
Methods and devices for renal nerve blocking
|
|
US8131371B2
(en)
|
2002-04-08 |
2012-03-06 |
Ardian, Inc. |
Methods and apparatus for monopolar renal neuromodulation
|
|
US20140018880A1
(en)
|
2002-04-08 |
2014-01-16 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods for monopolar renal neuromodulation
|
|
US7162303B2
(en)
|
2002-04-08 |
2007-01-09 |
Ardian, Inc. |
Renal nerve stimulation method and apparatus for treatment of patients
|
|
US9308043B2
(en)
|
2002-04-08 |
2016-04-12 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods for monopolar renal neuromodulation
|
|
US7653438B2
(en)
|
2002-04-08 |
2010-01-26 |
Ardian, Inc. |
Methods and apparatus for renal neuromodulation
|
|
US20070129761A1
(en)
|
2002-04-08 |
2007-06-07 |
Ardian, Inc. |
Methods for treating heart arrhythmia
|
|
US9308044B2
(en)
|
2002-04-08 |
2016-04-12 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods for therapeutic renal neuromodulation
|
|
US7756583B2
(en)
|
2002-04-08 |
2010-07-13 |
Ardian, Inc. |
Methods and apparatus for intravascularly-induced neuromodulation
|
|
US7853333B2
(en)
|
2002-04-08 |
2010-12-14 |
Ardian, Inc. |
Methods and apparatus for multi-vessel renal neuromodulation
|
|
US8774913B2
(en)
|
2002-04-08 |
2014-07-08 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods and apparatus for intravasculary-induced neuromodulation
|
|
US7617005B2
(en)
|
2002-04-08 |
2009-11-10 |
Ardian, Inc. |
Methods and apparatus for thermally-induced renal neuromodulation
|
|
US8347891B2
(en)
|
2002-04-08 |
2013-01-08 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
|
|
US8774922B2
(en)
|
2002-04-08 |
2014-07-08 |
Medtronic Ardian Luxembourg S.A.R.L. |
Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
|
|
US20110207758A1
(en)
|
2003-04-08 |
2011-08-25 |
Medtronic Vascular, Inc. |
Methods for Therapeutic Renal Denervation
|
|
US20080213331A1
(en)
|
2002-04-08 |
2008-09-04 |
Ardian, Inc. |
Methods and devices for renal nerve blocking
|
|
US8150519B2
(en)
|
2002-04-08 |
2012-04-03 |
Ardian, Inc. |
Methods and apparatus for bilateral renal neuromodulation
|
|
US20070135875A1
(en)
|
2002-04-08 |
2007-06-14 |
Ardian, Inc. |
Methods and apparatus for thermally-induced renal neuromodulation
|
|
US20040082859A1
(en)
|
2002-07-01 |
2004-04-29 |
Alan Schaer |
Method and apparatus employing ultrasound energy to treat body sphincters
|
|
US20040034336A1
(en)
*
|
2002-08-08 |
2004-02-19 |
Neal Scott |
Charged liposomes/micelles with encapsulted medical compounds
|
|
US7400931B2
(en)
*
|
2002-09-18 |
2008-07-15 |
Cardiac Pacemakers, Inc. |
Devices and methods to stimulate therapeutic angiogenesis for ischemia and heart failure
|
|
WO2004030630A2
(en)
*
|
2002-10-02 |
2004-04-15 |
The Johns Hopkins University |
Focal calcium channel modulation
|
|
US7072711B2
(en)
*
|
2002-11-12 |
2006-07-04 |
Cardiac Pacemakers, Inc. |
Implantable device for delivering cardiac drug therapy
|
|
US20050015048A1
(en)
*
|
2003-03-12 |
2005-01-20 |
Chiu Jessica G. |
Infusion treatment agents, catheters, filter devices, and occlusion devices, and use thereof
|
|
US7250041B2
(en)
*
|
2003-03-12 |
2007-07-31 |
Abbott Cardiovascular Systems Inc. |
Retrograde pressure regulated infusion
|
|
US7517342B2
(en)
*
|
2003-04-29 |
2009-04-14 |
Boston Scientific Scimed, Inc. |
Polymer coated device for electrically medicated drug delivery
|
|
US7330851B2
(en)
*
|
2003-08-18 |
2008-02-12 |
Eaglehawk, Limited |
Data security through dissembly of data elements or connections between elements
|
|
US20050131513A1
(en)
*
|
2003-12-16 |
2005-06-16 |
Cook Incorporated |
Stent catheter with a permanently affixed conductor
|
|
US7245973B2
(en)
|
2003-12-23 |
2007-07-17 |
Cardiac Pacemakers, Inc. |
His bundle mapping, pacing, and injection lead
|
|
US7840263B2
(en)
*
|
2004-02-27 |
2010-11-23 |
Cardiac Pacemakers, Inc. |
Method and apparatus for device controlled gene expression
|
|
US20050209548A1
(en)
*
|
2004-03-19 |
2005-09-22 |
Dev Sukhendu B |
Electroporation-mediated intravascular delivery
|
|
US20050226991A1
(en)
*
|
2004-04-07 |
2005-10-13 |
Hossainy Syed F |
Methods for modifying balloon of a catheter assembly
|
|
US7764995B2
(en)
|
2004-06-07 |
2010-07-27 |
Cardiac Pacemakers, Inc. |
Method and apparatus to modulate cellular regeneration post myocardial infarct
|
|
US7729761B2
(en)
*
|
2004-07-14 |
2010-06-01 |
Cardiac Pacemakers, Inc. |
Method and apparatus for controlled gene or protein delivery
|
|
US7567841B2
(en)
|
2004-08-20 |
2009-07-28 |
Cardiac Pacemakers, Inc. |
Method and apparatus for delivering combined electrical and drug therapies
|
|
US7937143B2
(en)
|
2004-11-02 |
2011-05-03 |
Ardian, Inc. |
Methods and apparatus for inducing controlled renal neuromodulation
|
|
US8290586B2
(en)
|
2004-12-20 |
2012-10-16 |
Cardiac Pacemakers, Inc. |
Methods, devices and systems for single-chamber pacing using a dual-chamber pacing device
|
|
US8005544B2
(en)
|
2004-12-20 |
2011-08-23 |
Cardiac Pacemakers, Inc. |
Endocardial pacing devices and methods useful for resynchronization and defibrillation
|
|
US8326423B2
(en)
|
2004-12-20 |
2012-12-04 |
Cardiac Pacemakers, Inc. |
Devices and methods for steering electrical stimulation in cardiac rhythm management
|
|
US8010191B2
(en)
|
2004-12-20 |
2011-08-30 |
Cardiac Pacemakers, Inc. |
Systems, devices and methods for monitoring efficiency of pacing
|
|
AR047851A1
(es)
|
2004-12-20 |
2006-03-01 |
Giniger Alberto German |
Un nuevo marcapasos que restablece o preserva la conduccion electrica fisiologica del corazon y un metodo de aplicacion
|
|
US8010192B2
(en)
|
2004-12-20 |
2011-08-30 |
Cardiac Pacemakers, Inc. |
Endocardial pacing relating to conduction abnormalities
|
|
US8423139B2
(en)
|
2004-12-20 |
2013-04-16 |
Cardiac Pacemakers, Inc. |
Methods, devices and systems for cardiac rhythm management using an electrode arrangement
|
|
US7850645B2
(en)
*
|
2005-02-11 |
2010-12-14 |
Boston Scientific Scimed, Inc. |
Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
|
|
EP1871890B1
(en)
*
|
2005-04-18 |
2011-06-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and devices for delivering a therapeutic product to the ocular sphere of a subject
|
|
US20060259088A1
(en)
*
|
2005-05-13 |
2006-11-16 |
Pastore Joseph M |
Method and apparatus for delivering pacing pulses using a coronary stent
|
|
US20060293730A1
(en)
*
|
2005-06-24 |
2006-12-28 |
Boris Rubinsky |
Methods and systems for treating restenosis sites using electroporation
|
|
US7608275B2
(en)
*
|
2005-07-22 |
2009-10-27 |
The Foundry, Llc |
Systems and methods for delivery of a therapeutic agent
|
|
US20070021803A1
(en)
|
2005-07-22 |
2007-01-25 |
The Foundry Inc. |
Systems and methods for neuromodulation for treatment of pain and other disorders associated with nerve conduction
|
|
EP1942946A4
(en)
*
|
2005-10-14 |
2009-11-25 |
Univ Johns Hopkins |
BIOLOGICALLY AVAILABLE CELLS
|
|
US7616990B2
(en)
|
2005-10-24 |
2009-11-10 |
Cardiac Pacemakers, Inc. |
Implantable and rechargeable neural stimulator
|
|
US20070149901A1
(en)
*
|
2005-12-08 |
2007-06-28 |
Em-Probe, Inc. |
Methods and apparatus for pulsed electromagnetic therapy
|
|
CN105056408B
(zh)
|
2006-06-28 |
2018-09-25 |
美敦力Af卢森堡公司 |
用于热诱导的肾神经调制的系统
|
|
JP2010506657A
(ja)
|
2006-10-16 |
2010-03-04 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
組織の不可逆的エレクトロポレーションに使用される、所定の導電率を有するゲル
|
|
US8738125B1
(en)
|
2007-03-30 |
2014-05-27 |
University Of South Florida |
Devices and methods for delivering molecules to the heart with electric fields
|
|
US10245098B2
(en)
|
2008-04-29 |
2019-04-02 |
Virginia Tech Intellectual Properties, Inc. |
Acute blood-brain barrier disruption using electrical energy based therapy
|
|
US9867652B2
(en)
|
2008-04-29 |
2018-01-16 |
Virginia Tech Intellectual Properties, Inc. |
Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
|
|
US10702326B2
(en)
|
2011-07-15 |
2020-07-07 |
Virginia Tech Intellectual Properties, Inc. |
Device and method for electroporation based treatment of stenosis of a tubular body part
|
|
US11272979B2
(en)
|
2008-04-29 |
2022-03-15 |
Virginia Tech Intellectual Properties, Inc. |
System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
|
|
US8992517B2
(en)
|
2008-04-29 |
2015-03-31 |
Virginia Tech Intellectual Properties Inc. |
Irreversible electroporation to treat aberrant cell masses
|
|
US10117707B2
(en)
|
2008-04-29 |
2018-11-06 |
Virginia Tech Intellectual Properties, Inc. |
System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
|
|
US9198733B2
(en)
|
2008-04-29 |
2015-12-01 |
Virginia Tech Intellectual Properties, Inc. |
Treatment planning for electroporation-based therapies
|
|
US9283051B2
(en)
|
2008-04-29 |
2016-03-15 |
Virginia Tech Intellectual Properties, Inc. |
System and method for estimating a treatment volume for administering electrical-energy based therapies
|
|
US10238447B2
(en)
|
2008-04-29 |
2019-03-26 |
Virginia Tech Intellectual Properties, Inc. |
System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
|
|
US11254926B2
(en)
|
2008-04-29 |
2022-02-22 |
Virginia Tech Intellectual Properties, Inc. |
Devices and methods for high frequency electroporation
|
|
US9598691B2
(en)
|
2008-04-29 |
2017-03-21 |
Virginia Tech Intellectual Properties, Inc. |
Irreversible electroporation to create tissue scaffolds
|
|
US10272178B2
(en)
|
2008-04-29 |
2019-04-30 |
Virginia Tech Intellectual Properties Inc. |
Methods for blood-brain barrier disruption using electrical energy
|
|
US8849395B2
(en)
*
|
2008-05-30 |
2014-09-30 |
Boston Scientific Scimed, Inc. |
Guide catheter having vasomodulating electrodes
|
|
US20100125238A1
(en)
*
|
2008-11-14 |
2010-05-20 |
Therawire, Inc. |
Iontophoretic Therapeutic Agent Delivery System
|
|
US8688234B2
(en)
|
2008-12-19 |
2014-04-01 |
Cardiac Pacemakers, Inc. |
Devices, methods, and systems including cardiac pacing
|
|
US8652129B2
(en)
|
2008-12-31 |
2014-02-18 |
Medtronic Ardian Luxembourg S.A.R.L. |
Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
|
|
US8808345B2
(en)
|
2008-12-31 |
2014-08-19 |
Medtronic Ardian Luxembourg S.A.R.L. |
Handle assemblies for intravascular treatment devices and associated systems and methods
|
|
US8974445B2
(en)
|
2009-01-09 |
2015-03-10 |
Recor Medical, Inc. |
Methods and apparatus for treatment of cardiac valve insufficiency
|
|
US8632534B2
(en)
|
2009-04-03 |
2014-01-21 |
Angiodynamics, Inc. |
Irreversible electroporation (IRE) for congestive obstructive pulmonary disease (COPD)
|
|
US11382681B2
(en)
|
2009-04-09 |
2022-07-12 |
Virginia Tech Intellectual Properties, Inc. |
Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
|
|
US11638603B2
(en)
|
2009-04-09 |
2023-05-02 |
Virginia Tech Intellectual Properties, Inc. |
Selective modulation of intracellular effects of cells using pulsed electric fields
|
|
WO2010138919A2
(en)
|
2009-05-28 |
2010-12-02 |
Angiodynamics, Inc. |
System and method for synchronizing energy delivery to the cardiac rhythm
|
|
JP5850501B2
(ja)
*
|
2009-06-09 |
2016-02-03 |
ニューロナノ アーベー |
微小電極
|
|
US9895189B2
(en)
|
2009-06-19 |
2018-02-20 |
Angiodynamics, Inc. |
Methods of sterilization and treating infection using irreversible electroporation
|
|
US20110112400A1
(en)
*
|
2009-11-06 |
2011-05-12 |
Ardian, Inc. |
High intensity focused ultrasound catheter apparatuses, systems, and methods for renal neuromodulation
|
|
EP2525715A4
(en)
*
|
2010-01-19 |
2014-06-04 |
Medtronic Ardian Luxembourg S R L |
METHODS AND APPARATUS FOR RENAL NEUROMODULATION BY STEREOTACTIC RADIOTHERAPY
|
|
US20110208173A1
(en)
*
|
2010-02-24 |
2011-08-25 |
Medtronic Vascular, Inc. |
Methods for Treating sleep apnea via renal Denervation
|
|
US8556891B2
(en)
|
2010-03-03 |
2013-10-15 |
Medtronic Ablation Frontiers Llc |
Variable-output radiofrequency ablation power supply
|
|
US8870863B2
(en)
|
2010-04-26 |
2014-10-28 |
Medtronic Ardian Luxembourg S.A.R.L. |
Catheter apparatuses, systems, and methods for renal neuromodulation
|
|
US8565880B2
(en)
|
2010-04-27 |
2013-10-22 |
Cardiac Pacemakers, Inc. |
His-bundle capture verification and monitoring
|
|
EP2600784B1
(en)
|
2010-08-05 |
2021-12-29 |
Medtronic Ireland Manufacturing Unlimited Company |
Cryoablation apparatuses, systems, and methods for renal neuromodulation
|
|
WO2012051433A2
(en)
|
2010-10-13 |
2012-04-19 |
Angiodynamics, Inc. |
System and method for electrically ablating tissue of a patient
|
|
TWI556849B
(zh)
|
2010-10-21 |
2016-11-11 |
美敦力阿福盧森堡公司 |
用於腎臟神經協調的導管裝置
|
|
TWI586399B
(zh)
|
2010-10-25 |
2017-06-11 |
美敦力阿福盧森堡公司 |
用於腎臟神經協調之具有多電極陣列的導管
|
|
EP3449856B1
(en)
|
2010-10-25 |
2023-06-28 |
Medtronic Ardian Luxembourg S.à.r.l. |
Device for evaluation and feedback of neuromodulation treatment
|
|
CN103179914B
(zh)
|
2010-10-25 |
2016-11-09 |
美敦力Af卢森堡有限责任公司 |
用于肾神经调节的微波导管设备
|
|
US9066713B2
(en)
|
2010-10-26 |
2015-06-30 |
Medtronic Ardian Luxembourg S.A.R.L. |
Neuromodulation cryotherapeutic devices and associated systems and methods
|
|
US9060754B2
(en)
|
2010-10-26 |
2015-06-23 |
Medtronic Ardian Luxembourg S.A.R.L. |
Neuromodulation cryotherapeutic devices and associated systems and methods
|
|
EP2640293B1
(en)
|
2010-11-17 |
2022-09-07 |
Medtronic Ireland Manufacturing Unlimited Company |
Systems for therapeutic renal neuromodulation for treating dyspnea
|
|
WO2012088149A2
(en)
|
2010-12-20 |
2012-06-28 |
Virginia Tech Intellectual Properties, Inc. |
High-frequency electroporation for cancer therapy
|
|
US8761880B2
(en)
|
2011-03-14 |
2014-06-24 |
Cardiac Pacemakers, Inc. |
His capture verification using electro-mechanical delay
|
|
CN103517731B
(zh)
|
2011-04-08 |
2016-08-31 |
柯惠有限合伙公司 |
用于去除肾交感神经和离子电渗式药物传递的离子电渗式药物传递系统和方法
|
|
CN103930061B
(zh)
|
2011-04-25 |
2016-09-14 |
美敦力阿迪安卢森堡有限责任公司 |
用于限制导管壁低温消融的有关低温球囊限制部署的装置及方法
|
|
US9078665B2
(en)
|
2011-09-28 |
2015-07-14 |
Angiodynamics, Inc. |
Multiple treatment zone ablation probe
|
|
EP3287067B1
(en)
|
2011-11-07 |
2019-10-30 |
Medtronic Ardian Luxembourg S.à.r.l. |
Endovascular nerve monitoring devices and associated systems
|
|
US9192766B2
(en)
|
2011-12-02 |
2015-11-24 |
Medtronic Ardian Luxembourg S.A.R.L. |
Renal neuromodulation methods and devices for treatment of polycystic kidney disease
|
|
US9414881B2
(en)
|
2012-02-08 |
2016-08-16 |
Angiodynamics, Inc. |
System and method for increasing a target zone for electrical ablation
|
|
WO2013134469A1
(en)
|
2012-03-07 |
2013-09-12 |
Medtronic Ardian Luxembourg Sarl |
Selective modulation of renal nerves
|
|
US10737123B2
(en)
|
2012-03-08 |
2020-08-11 |
Medtronic Ardian Luxembourg S.A.R.L. |
Neuromodulation and associated systems and methods for the management of pain
|
|
US11013549B2
(en)
|
2012-03-08 |
2021-05-25 |
Medtronic Ardian Luxembourg S.A.R.L. |
Gastrointestinal neuromodulation and associated systems and methods
|
|
US9974593B2
(en)
|
2012-03-08 |
2018-05-22 |
Medtronic Ardian Luxembourg S.A.R.L. |
Neuromodulation and associated systems and methods for the treatment of sexual dysfunction
|
|
US9750568B2
(en)
|
2012-03-08 |
2017-09-05 |
Medtronic Ardian Luxembourg S.A.R.L. |
Ovarian neuromodulation and associated systems and methods
|
|
CN107260134B
(zh)
|
2012-03-08 |
2021-06-08 |
美敦力Af卢森堡有限责任公司 |
采用神经调节装置的生物标志物取样和相关系统及方法
|
|
US9883909B2
(en)
|
2012-03-08 |
2018-02-06 |
Medtronic Ardian Luxembourg S.A.R.L. |
Renal neuromodulation methods and systems for treatment of hyperaldosteronism
|
|
US9241752B2
(en)
|
2012-04-27 |
2016-01-26 |
Medtronic Ardian Luxembourg S.A.R.L. |
Shafts with pressure relief in cryotherapeutic catheters and associated devices, systems, and methods
|
|
EP2840991B1
(en)
|
2012-04-27 |
2019-05-15 |
Medtronic Ardian Luxembourg S.à.r.l. |
Cryotherapeutic devices for renal neuromodulation
|
|
WO2013162722A1
(en)
|
2012-04-27 |
2013-10-31 |
Medtronic Ardian Luxembourg Sarl |
Methods and devices for localized disease treatment by ablation
|
|
US10258791B2
(en)
|
2012-04-27 |
2019-04-16 |
Medtronic Ardian Luxembourg S.A.R.L. |
Catheter assemblies for neuromodulation proximate a bifurcation of a renal artery and associated systems and methods
|
|
WO2013162721A1
(en)
|
2012-04-27 |
2013-10-31 |
Medtronic Ardian Luxembourg Sarl |
Methods and devices for localized inhibition of inflammation by ablation
|
|
CA2872189A1
(en)
|
2012-05-11 |
2013-11-14 |
William W. CHANG |
Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods
|
|
US8951296B2
(en)
|
2012-06-29 |
2015-02-10 |
Medtronic Ardian Luxembourg S.A.R.L. |
Devices and methods for photodynamically modulating neural function in a human
|
|
CN105188767A
(zh)
|
2012-07-25 |
2015-12-23 |
布罗德研究所有限公司 |
可诱导的dna结合蛋白和基因组干扰工具及其应用
|
|
US8612022B1
(en)
|
2012-09-13 |
2013-12-17 |
Invatec S.P.A. |
Neuromodulation catheters and associated systems and methods
|
|
US20140110296A1
(en)
|
2012-10-19 |
2014-04-24 |
Medtronic Ardian Luxembourg S.A.R.L. |
Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods
|
|
US9044575B2
(en)
|
2012-10-22 |
2015-06-02 |
Medtronic Adrian Luxembourg S.a.r.l. |
Catheters with enhanced flexibility and associated devices, systems, and methods
|
|
US9399115B2
(en)
|
2012-10-22 |
2016-07-26 |
Medtronic Ardian Luxembourg S.A.R.L. |
Catheters with enhanced flexibility and associated devices, systems, and methods
|
|
US9095321B2
(en)
|
2012-11-21 |
2015-08-04 |
Medtronic Ardian Luxembourg S.A.R.L. |
Cryotherapeutic devices having integral multi-helical balloons and methods of making the same
|
|
US9017317B2
(en)
|
2012-12-06 |
2015-04-28 |
Medtronic Ardian Luxembourg S.A.R.L. |
Refrigerant supply system for cryotherapy including refrigerant recompression and associated devices, systems, and methods
|
|
US9179974B2
(en)
|
2013-03-15 |
2015-11-10 |
Medtronic Ardian Luxembourg S.A.R.L. |
Helical push wire electrode
|
|
WO2014145146A1
(en)
|
2013-03-15 |
2014-09-18 |
Medtronic Ardian Luxembourg S.A.R.L. |
Controlled neuromodulation systems and methods of use
|
|
US9066726B2
(en)
|
2013-03-15 |
2015-06-30 |
Medtronic Ardian Luxembourg S.A.R.L. |
Multi-electrode apposition judgment using pressure elements
|
|
US10548663B2
(en)
|
2013-05-18 |
2020-02-04 |
Medtronic Ardian Luxembourg S.A.R.L. |
Neuromodulation catheters with shafts for enhanced flexibility and control and associated devices, systems, and methods
|
|
US9339332B2
(en)
|
2013-08-30 |
2016-05-17 |
Medtronic Ardian Luxembourg S.A.R.L. |
Neuromodulation catheters with nerve monitoring features for transmitting digital neural signals and associated systems and methods
|
|
US9326816B2
(en)
|
2013-08-30 |
2016-05-03 |
Medtronic Ardian Luxembourg S.A.R.L. |
Neuromodulation systems having nerve monitoring assemblies and associated devices, systems, and methods
|
|
US20150073515A1
(en)
|
2013-09-09 |
2015-03-12 |
Medtronic Ardian Luxembourg S.a.r.I. |
Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods
|
|
US9138578B2
(en)
|
2013-09-10 |
2015-09-22 |
Medtronic Ardian Luxembourg S.A.R.L. |
Endovascular catheters with tuned control members and associated systems and methods
|
|
US10433902B2
(en)
|
2013-10-23 |
2019-10-08 |
Medtronic Ardian Luxembourg S.A.R.L. |
Current control methods and systems
|
|
EP3099377B1
(en)
|
2014-01-27 |
2022-03-02 |
Medtronic Ireland Manufacturing Unlimited Company |
Neuromodulation catheters having jacketed neuromodulation elements and related devices
|
|
US10492842B2
(en)
|
2014-03-07 |
2019-12-03 |
Medtronic Ardian Luxembourg S.A.R.L. |
Monitoring and controlling internally administered cryotherapy
|
|
US10463424B2
(en)
|
2014-03-11 |
2019-11-05 |
Medtronic Ardian Luxembourg S.A.R.L. |
Catheters with independent radial-expansion members and associated devices, systems, and methods
|
|
US9579149B2
(en)
|
2014-03-13 |
2017-02-28 |
Medtronic Ardian Luxembourg S.A.R.L. |
Low profile catheter assemblies and associated systems and methods
|
|
US10194980B1
(en)
|
2014-03-28 |
2019-02-05 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods for catheter-based renal neuromodulation
|
|
US10194979B1
(en)
|
2014-03-28 |
2019-02-05 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods for catheter-based renal neuromodulation
|
|
US9980766B1
(en)
|
2014-03-28 |
2018-05-29 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods and systems for renal neuromodulation
|
|
EP4371512A3
(en)
|
2014-04-24 |
2024-08-14 |
Medtronic Ardian Luxembourg S.à.r.l. |
Neuromodulation catheters having braided shafts and associated systems and methods
|
|
US10610292B2
(en)
|
2014-04-25 |
2020-04-07 |
Medtronic Ardian Luxembourg S.A.R.L. |
Devices, systems, and methods for monitoring and/or controlling deployment of a neuromodulation element within a body lumen and related technology
|
|
US10918840B2
(en)
|
2014-05-06 |
2021-02-16 |
Hydra Vascular Llc |
Drug device electroporation system
|
|
US10709490B2
(en)
|
2014-05-07 |
2020-07-14 |
Medtronic Ardian Luxembourg S.A.R.L. |
Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods
|
|
CN112807074A
(zh)
|
2014-05-12 |
2021-05-18 |
弗吉尼亚暨州立大学知识产权公司 |
电穿孔系统
|
|
US12114911B2
(en)
|
2014-08-28 |
2024-10-15 |
Angiodynamics, Inc. |
System and method for ablating a tissue site by electroporation with real-time pulse monitoring
|
|
US11154712B2
(en)
|
2014-08-28 |
2021-10-26 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods for assessing efficacy of renal neuromodulation and associated systems and devices
|
|
US10368775B2
(en)
|
2014-10-01 |
2019-08-06 |
Medtronic Ardian Luxembourg S.A.R.L. |
Systems and methods for evaluating neuromodulation therapy via hemodynamic responses
|
|
CN107530124B
(zh)
|
2014-11-14 |
2021-07-20 |
美敦力阿迪安卢森堡有限公司 |
用于调节与肺部系统通信的神经的导管设备及相关联的系统和方法
|
|
WO2016094874A1
(en)
|
2014-12-12 |
2016-06-16 |
The Broad Institute Inc. |
Escorted and functionalized guides for crispr-cas systems
|
|
WO2016100325A1
(en)
|
2014-12-15 |
2016-06-23 |
Virginia Tech Intellectual Properties, Inc. |
Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
|
|
WO2016100720A1
(en)
|
2014-12-17 |
2016-06-23 |
Medtronic Ardian Luxembourg S.A.R.L. |
Systems and methods for assessing sympathetic nervous system tone for renal neuromodulation therapy
|
|
MX392008B
(es)
|
2015-06-18 |
2025-03-21 |
Broad Inst Inc |
Mutaciones de la enzima crispr que reducen los efectos fuera del blanco
|
|
CN108135653B
(zh)
|
2015-10-07 |
2022-02-11 |
梅约医学教育与研究基金会 |
用于肥胖症或糖尿病治疗的电穿孔
|
|
WO2017106657A1
(en)
|
2015-12-18 |
2017-06-22 |
The Broad Institute Inc. |
Novel crispr enzymes and systems
|
|
SG10202010311SA
(en)
|
2016-04-19 |
2020-11-27 |
Broad Inst Inc |
Novel Crispr Enzymes and Systems
|
|
EP3445856A1
(en)
|
2016-04-19 |
2019-02-27 |
The Broad Institute Inc. |
Novel crispr enzymes and systems
|
|
AU2017253107B2
(en)
|
2016-04-19 |
2023-07-20 |
Massachusetts Institute Of Technology |
CPF1 complexes with reduced indel activity
|
|
US10736692B2
(en)
|
2016-04-28 |
2020-08-11 |
Medtronic Ardian Luxembourg S.A.R.L. |
Neuromodulation and associated systems and methods for the treatment of cancer
|
|
US20210222164A1
(en)
|
2016-06-29 |
2021-07-22 |
The Broad Institute, Inc. |
Crispr-cas systems having destabilization domain
|
|
US10231784B2
(en)
|
2016-10-28 |
2019-03-19 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods and systems for optimizing perivascular neuromodulation therapy using computational fluid dynamics
|
|
US10905492B2
(en)
|
2016-11-17 |
2021-02-02 |
Angiodynamics, Inc. |
Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
|
|
US10646713B2
(en)
|
2017-02-22 |
2020-05-12 |
Medtronic Ardian Luxembourg S.A.R.L. |
Systems, devices, and associated methods for treating patients via renal neuromodulation to reduce a risk of developing cognitive impairment
|
|
WO2018175924A1
(en)
|
2017-03-24 |
2018-09-27 |
The Broad Institute, Inc. |
Methods and compositions for regulating innate lymphoid cell inflammatory responses
|
|
US11963966B2
(en)
|
2017-03-31 |
2024-04-23 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
|
WO2018191553A1
(en)
|
2017-04-12 |
2018-10-18 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
|
US12226479B2
(en)
|
2017-05-11 |
2025-02-18 |
The General Hospital Corporation |
Methods and compositions of use of CD8+ tumor infiltrating lymphocyte subtypes and gene signatures thereof
|
|
WO2018213726A1
(en)
|
2017-05-18 |
2018-11-22 |
The Broad Institute, Inc. |
Systems, methods, and compositions for targeted nucleic acid editing
|
|
EP3638218A4
(en)
|
2017-06-14 |
2021-06-09 |
The Broad Institute, Inc. |
COMPOSITIONS AND METHOD OF TARGETING COMPLEMENTING COMPONENT 3 FOR INHIBITION OF TUMOR GROWTH
|
|
CN111328290A
(zh)
|
2017-06-26 |
2020-06-23 |
博德研究所 |
用于靶向核酸编辑的基于crispr/cas-腺嘌呤脱氨酶的组合物、系统和方法
|
|
US11160982B2
(en)
|
2017-07-05 |
2021-11-02 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods for treating post-traumatic stress disorder in patients via renal neuromodulation
|
|
US10945788B2
(en)
|
2017-07-05 |
2021-03-16 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods for treating depression in patients via renal neuromodulation
|
|
US11284934B2
(en)
|
2017-07-05 |
2022-03-29 |
Medtronic Ardian Luxembourg S.A.R.L. |
Methods for treating sleep disorders in patients via renal neuromodulation
|
|
US12049643B2
(en)
|
2017-07-14 |
2024-07-30 |
The Broad Institute, Inc. |
Methods and compositions for modulating cytotoxic lymphocyte activity
|
|
EP3654993A4
(en)
|
2017-07-17 |
2021-08-25 |
The Broad Institute, Inc. |
CELL ATLAS OF HEALTHY HUMAN COLUMN AND HUMAN COLUMN WITH COLITIS ULCEROSA
|
|
JP2020536580A
(ja)
|
2017-09-19 |
2020-12-17 |
ザ ステート オブ イスラエル， ミニストリー オブ アグリカルチャー アンド ルーラル ディヴェロプメント， アグリカルチュラル リサーチ オーガニゼーション （エーアールオー） （ボルカニ センター） |
ゲノム編集された鳥
|
|
WO2019060746A1
(en)
|
2017-09-21 |
2019-03-28 |
The Broad Institute, Inc. |
SYSTEMS, METHODS, AND COMPOSITIONS FOR THE TARGETED EDITING OF NUCLEIC ACIDS
|
|
US20200255828A1
(en)
|
2017-10-04 |
2020-08-13 |
The Broad Institute, Inc. |
Methods and compositions for altering function and structure of chromatin loops and/or domains
|
|
WO2019135816A2
(en)
|
2017-10-23 |
2019-07-11 |
The Broad Institute, Inc. |
Novel nucleic acid modifiers
|
|
WO2019094955A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for targeting developmental and oncogenic programs in h3k27m gliomas
|
|
US12221720B2
(en)
|
2017-11-13 |
2025-02-11 |
The Broad Institute, Inc. |
Methods for determining spatial and temporal gene expression dynamics during adult neurogenesis in single cells
|
|
WO2019094983A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for treating cancer by targeting the clec2d-klrb1 pathway
|
|
WO2019097296A1
(en)
|
2017-11-17 |
2019-05-23 |
Medtronic Ardian Luxembourg S.A.R.L. |
Systems, devices, and associated methods for neuromodulation with enhanced nerve targeting
|
|
US11607537B2
(en)
|
2017-12-05 |
2023-03-21 |
Virginia Tech Intellectual Properties, Inc. |
Method for treating neurological disorders, including tumors, with electroporation
|
|
US11332736B2
(en)
|
2017-12-07 |
2022-05-17 |
The Broad Institute, Inc. |
Methods and compositions for multiplexing single cell and single nuclei sequencing
|
|
WO2019126709A1
(en)
|
2017-12-22 |
2019-06-27 |
The Broad Institute, Inc. |
Cas12b systems, methods, and compositions for targeted dna base editing
|
|
US11994512B2
(en)
|
2018-01-04 |
2024-05-28 |
Massachusetts Institute Of Technology |
Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
|
|
US11253189B2
(en)
|
2018-01-24 |
2022-02-22 |
Medtronic Ardian Luxembourg S.A.R.L. |
Systems, devices, and methods for evaluating neuromodulation therapy via detection of magnetic fields
|
|
US10959669B2
(en)
|
2018-01-24 |
2021-03-30 |
Medtronic Ardian Luxembourg S.A.R.L. |
Systems and methods for assessing the efficacy of neuromodulation therapy
|
|
US12082917B2
(en)
|
2018-01-24 |
2024-09-10 |
Medtronic Ireland Manufacturing Unlimited Company |
Systems, devices, and methods for assessing efficacy of renal neuromodulation therapy
|
|
US11478298B2
(en)
|
2018-01-24 |
2022-10-25 |
Medtronic Ardian Luxembourg S.A.R.L. |
Controlled irrigation for neuromodulation systems and associated methods
|
|
US12458435B2
(en)
|
2018-01-24 |
2025-11-04 |
Medtronic Ireland Manufacturing Unlimited Company |
Multielectrode catheter
|
|
US11116561B2
(en)
|
2018-01-24 |
2021-09-14 |
Medtronic Ardian Luxembourg S.A.R.L. |
Devices, agents, and associated methods for selective modulation of renal nerves
|
|
US12390262B2
(en)
|
2018-03-13 |
2025-08-19 |
Virginia Tech Intellectual Properties, Inc. |
Treatment planning system for immunotherapy enhancement via non-thermal ablation
|
|
US11925405B2
(en)
|
2018-03-13 |
2024-03-12 |
Virginia Tech Intellectual Properties, Inc. |
Treatment planning system for immunotherapy enhancement via non-thermal ablation
|
|
US11311329B2
(en)
|
2018-03-13 |
2022-04-26 |
Virginia Tech Intellectual Properties, Inc. |
Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
|
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
|
US12281301B2
(en)
|
2018-04-27 |
2025-04-22 |
The Broad Institute, Inc. |
Sequencing-based proteomics
|
|
US20210371932A1
(en)
|
2018-06-01 |
2021-12-02 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
|
US12036240B2
(en)
|
2018-06-14 |
2024-07-16 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
AU2019318079B2
(en)
|
2018-08-07 |
2025-12-04 |
Massachusetts Institute Of Technology |
Novel Cas12b enzymes and systems
|
|
US12460244B2
(en)
|
2018-08-20 |
2025-11-04 |
The Broad Institute, Inc. |
Inhibitors of RNA-guided nuclease activity and uses thereof
|
|
US20210324357A1
(en)
|
2018-08-20 |
2021-10-21 |
The Brigham And Women's Hospital, Inc. |
Degradation domain modifications for spatio-temporal control of rna-guided nucleases
|
|
US12421507B2
(en)
|
2018-08-20 |
2025-09-23 |
The Broad Institute, Inc. |
Methods and compositions for optochemical control of CRISPR-CAS9
|
|
US11633120B2
(en)
|
2018-09-04 |
2023-04-25 |
Medtronic Ardian Luxembourg S.A.R.L. |
Systems and methods for assessing efficacy of renal neuromodulation therapy
|
|
EP3847650A1
(en)
|
2018-09-06 |
2021-07-14 |
The Broad Institute, Inc. |
Nucleic acid assemblies for use in targeted delivery
|
|
AU2019343045A1
(en)
|
2018-09-18 |
2021-05-13 |
Vnv Newco Inc. |
ARC-based capsids and uses thereof
|
|
WO2020077135A1
(en)
|
2018-10-10 |
2020-04-16 |
Dana-Farber Cancer Institute, Inc. |
Modulating resistance to bcl-2 inhibitors
|
|
US20220411783A1
(en)
|
2018-10-12 |
2022-12-29 |
The Broad Institute, Inc. |
Method for extracting nuclei or whole cells from formalin-fixed paraffin-embedded tissues
|
|
WO2020081730A2
(en)
|
2018-10-16 |
2020-04-23 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating microenvironment
|
|
US12165743B2
(en)
|
2018-11-09 |
2024-12-10 |
The Broad Institute, Inc. |
Compressed sensing for screening and tissue imaging
|
|
US12402610B2
(en)
|
2018-11-09 |
2025-09-02 |
The Broad Institute, Inc. |
Methods and compositions for modulating innate lymphoid cell pathogenic effectors
|
|
WO2020102610A1
(en)
|
2018-11-14 |
2020-05-22 |
The Broad Institute, Inc. |
Crispr system based droplet diagnostic systems and methods
|
|
US20250043366A1
(en)
|
2018-12-13 |
2025-02-06 |
The Broad Institute, Inc. |
Tiled assays using crispr-cas based detection
|
|
US11384344B2
(en)
|
2018-12-17 |
2022-07-12 |
The Broad Institute, Inc. |
CRISPR-associated transposase systems and methods of use thereof
|
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
|
CA3128360A1
(en)
|
2019-03-05 |
2020-09-10 |
Yuval CINNAMON |
Genome-edited birds
|
|
US12534714B2
(en)
|
2019-03-18 |
2026-01-27 |
The Broad Institute, Inc. |
Type VII CRISPR proteins and systems
|
|
EP3947687A1
(en)
|
2019-03-29 |
2022-02-09 |
Massachusetts Institute of Technology |
Constructs for continuous monitoring of live cells
|
|
US20220162649A1
(en)
|
2019-04-01 |
2022-05-26 |
The Broad Institute, Inc. |
Novel nucleic acid modifiers
|
|
US20220220469A1
(en)
|
2019-05-20 |
2022-07-14 |
The Broad Institute, Inc. |
Non-class i multi-component nucleic acid targeting systems
|
|
WO2020236967A1
(en)
|
2019-05-20 |
2020-11-26 |
The Broad Institute, Inc. |
Random crispr-cas deletion mutant
|
|
WO2020243661A1
(en)
|
2019-05-31 |
2020-12-03 |
The Broad Institute, Inc. |
Methods for treating metabolic disorders by targeting adcy5
|
|
US11950835B2
(en)
|
2019-06-28 |
2024-04-09 |
Virginia Tech Intellectual Properties, Inc. |
Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy
|
|
US12214189B2
(en)
|
2019-07-24 |
2025-02-04 |
Virginia Tech Intellectual Properties, Inc. |
Fourier analysis spectroscopy for monitoring tissue impedance changes and treatment outcome during electroporation-based-therapies
|
|
WO2021041922A1
(en)
|
2019-08-30 |
2021-03-04 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
|
US12297426B2
(en)
|
2019-10-01 |
2025-05-13 |
The Broad Institute, Inc. |
DNA damage response signature guided rational design of CRISPR-based systems and therapies
|
|
US11981922B2
(en)
|
2019-10-03 |
2024-05-14 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
|
|
EP4048179A1
(en)
|
2019-10-21 |
2022-08-31 |
Endogenex, Inc. |
Devices, systems, and methods for pulsed electric field treatment of the duodenum
|
|
US12165747B2
(en)
|
2020-01-23 |
2024-12-10 |
The Broad Institute, Inc. |
Molecular spatial mapping of metastatic tumor microenvironment
|
|
US12485279B2
(en)
|
2020-11-25 |
2025-12-02 |
Virginia Tech Intellectual Properties, Inc. |
Methods for modulating temporal infrastructure of pulsed electric fields
|
|
WO2025117544A1
(en)
|
2023-11-29 |
2025-06-05 |
The Broad Institute, Inc. |
Engineered omega guide molecule and iscb compositions, systems, and methods of use thereof
|