CA2258829C - Electroporation-mediated intravascular delivery - Google Patents
Electroporation-mediated intravascular delivery Download PDFInfo
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- CA2258829C CA2258829C CA002258829A CA2258829A CA2258829C CA 2258829 C CA2258829 C CA 2258829C CA 002258829 A CA002258829 A CA 002258829A CA 2258829 A CA2258829 A CA 2258829A CA 2258829 C CA2258829 C CA 2258829C
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
- A61N1/303—Constructional details
- A61N1/306—Arrangements where at least part of the apparatus is introduced into the body
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/668,725 | 1996-06-24 | ||
| US08/668,725 US5944710A (en) | 1996-06-24 | 1996-06-24 | Electroporation-mediated intravascular delivery |
| PCT/US1997/010975 WO1997049450A1 (en) | 1996-06-24 | 1997-06-23 | Electroporation-mediated intravascular delivery |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2258829A1 CA2258829A1 (en) | 1997-12-31 |
| CA2258829C true CA2258829C (en) | 2007-12-18 |
Family
ID=24683482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002258829A Expired - Fee Related CA2258829C (en) | 1996-06-24 | 1997-06-23 | Electroporation-mediated intravascular delivery |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US5944710A (enExample) |
| EP (1) | EP0915721B1 (enExample) |
| JP (1) | JP4126095B2 (enExample) |
| CA (1) | CA2258829C (enExample) |
| DE (1) | DE69735763T2 (enExample) |
| WO (1) | WO1997049450A1 (enExample) |
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| US12165747B2 (en) | 2020-01-23 | 2024-12-10 | The Broad Institute, Inc. | Molecular spatial mapping of metastatic tumor microenvironment |
| US12485279B2 (en) | 2020-11-25 | 2025-12-02 | Virginia Tech Intellectual Properties, Inc. | Methods for modulating temporal infrastructure of pulsed electric fields |
| WO2025117544A1 (en) | 2023-11-29 | 2025-06-05 | The Broad Institute, Inc. | Engineered omega guide molecule and iscb compositions, systems, and methods of use thereof |
Family Cites Families (11)
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|---|---|---|---|---|
| GB1481480A (en) * | 1974-02-02 | 1977-07-27 | Kernforschungsanlage Juelich | Process and apparatus for increasing the permeability of the membrane of cells of organisms |
| US4747819A (en) * | 1984-10-29 | 1988-05-31 | Medtronic, Inc. | Iontophoretic drug delivery |
| US4663292A (en) * | 1984-12-21 | 1987-05-05 | Wong Daniel T | High-voltage biological macromolecule transfer and cell fusion system |
| WO1989006555A1 (en) * | 1988-01-21 | 1989-07-27 | Massachusetts Institute Of Technology | Transport of molecules across tissue using electroporation |
| US5088977A (en) * | 1988-12-21 | 1992-02-18 | Drug Delivery Systems Inc. | Electrical transdermal drug applicator with counteractor and method of drug delivery |
| US5236413B1 (en) * | 1990-05-07 | 1996-06-18 | Andrew J Feiring | Method and apparatus for inducing the permeation of medication into internal tissue |
| US5498238A (en) * | 1990-06-15 | 1996-03-12 | Cortrak Medical, Inc. | Simultaneous angioplasty and phoretic drug delivery |
| CA2074304C (en) * | 1991-08-02 | 1996-11-26 | Cyril J. Schweich, Jr. | Drug delivery catheter |
| US5304120A (en) * | 1992-07-01 | 1994-04-19 | Btx Inc. | Electroporation method and apparatus for insertion of drugs and genes into endothelial cells |
| US5507724A (en) * | 1992-07-01 | 1996-04-16 | Genetronics, Inc. | Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells |
| US5634899A (en) * | 1993-08-20 | 1997-06-03 | Cortrak Medical, Inc. | Simultaneous cardiac pacing and local drug delivery method |
-
1996
- 1996-06-24 US US08/668,725 patent/US5944710A/en not_active Expired - Fee Related
-
1997
- 1997-06-23 DE DE69735763T patent/DE69735763T2/de not_active Expired - Lifetime
- 1997-06-23 WO PCT/US1997/010975 patent/WO1997049450A1/en not_active Ceased
- 1997-06-23 EP EP97932266A patent/EP0915721B1/en not_active Expired - Lifetime
- 1997-06-23 JP JP50348098A patent/JP4126095B2/ja not_active Expired - Fee Related
- 1997-06-23 CA CA002258829A patent/CA2258829C/en not_active Expired - Fee Related
-
2001
- 2001-12-14 US US10/020,531 patent/US20020045853A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000515400A (ja) | 2000-11-21 |
| EP0915721A4 (en) | 2004-08-18 |
| DE69735763T2 (de) | 2007-05-10 |
| EP0915721B1 (en) | 2006-04-26 |
| WO1997049450A1 (en) | 1997-12-31 |
| US20020045853A1 (en) | 2002-04-18 |
| JP4126095B2 (ja) | 2008-07-30 |
| CA2258829A1 (en) | 1997-12-31 |
| EP0915721A1 (en) | 1999-05-19 |
| US5944710A (en) | 1999-08-31 |
| DE69735763D1 (de) | 2006-06-01 |
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