JP2000515363A - Ｍｈｃ複合体及びその用途 - Google Patents
Ｍｈｃ複合体及びその用途Info
- Publication number
- JP2000515363A JP2000515363A JP09527863A JP52786397A JP2000515363A JP 2000515363 A JP2000515363 A JP 2000515363A JP 09527863 A JP09527863 A JP 09527863A JP 52786397 A JP52786397 A JP 52786397A JP 2000515363 A JP2000515363 A JP 2000515363A
- Authority
- JP
- Japan
- Prior art keywords
- mhc
- complex
- peptide
- cells
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6043—Heat shock proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
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- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Psychiatry (AREA)
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- Pain & Pain Management (AREA)
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- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/596,387 US5869270A (en) | 1996-01-31 | 1996-01-31 | Single chain MHC complexes and uses thereof |
| US08/596,387 | 1996-01-31 | ||
| PCT/US1997/001617 WO1997028191A1 (en) | 1996-01-31 | 1997-01-30 | Mhc complexes and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000515363A true JP2000515363A (ja) | 2000-11-21 |
| JP2000515363A5 JP2000515363A5 (enExample) | 2004-11-11 |
Family
ID=24387103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP09527863A Pending JP2000515363A (ja) | 1996-01-31 | 1997-01-30 | Ｍｈｃ複合体及びその用途 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US5869270A (enExample) |
| EP (2) | EP1526141A3 (enExample) |
| JP (1) | JP2000515363A (enExample) |
| AT (1) | ATE276275T1 (enExample) |
| AU (1) | AU729672B2 (enExample) |
| CA (1) | CA2244755A1 (enExample) |
| DE (1) | DE69730693T2 (enExample) |
| DK (1) | DK0877760T3 (enExample) |
| WO (1) | WO1997028191A1 (enExample) |
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| JP2011182702A (ja) * | 2010-03-08 | 2011-09-22 | Tokyo Univ Of Agriculture & Technology | 融合ｍｈｃ分子連結磁気微粒子、抗原ペプチドのスクリーニング方法、組換えベクター、及び磁性細菌の形質転換体 |
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| US11505591B2 (en) | 2016-05-18 | 2022-11-22 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
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| US5869270A (en) | 1996-01-31 | 1999-02-09 | Sunol Molecular Corporation | Single chain MHC complexes and uses thereof |
| US6458354B1 (en) | 1996-03-28 | 2002-10-01 | The Johns Hopkins University | Molecular complexes which modify immune responses |
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| US6211342B1 (en) * | 1996-07-18 | 2001-04-03 | Children's Hospital Medical Center | Multivalent MHC complex peptide fusion protein complex for stimulating specific T cell function |
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| GB2339782A (en) * | 1998-06-05 | 2000-02-09 | Philip Michael Savage | Chimeric protein complexes comprising HLA class I antigens |
| BR0008645A (pt) | 1999-03-03 | 2002-01-22 | Univ Pennsylvania | Métodos de induzir uma resposta imunológica contra um imunógeno em um indivìduo, de reduzir rejeição de células, tecido ou órgão doadores nã0-assemelhados em um indivìduo e uma resposta imunológica dominante em um indivìduo e de expandir uma subpopulação de células t associadas com uma resposta imunológica especìfica, plasmìdeo, e, composição |
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| EP0889964A1 (en) * | 1996-03-28 | 1999-01-13 | The Johns Hopkins University | Soluble divalent and multivalent heterodimeric analogs of proteins |
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1996
- 1996-01-31 US US08/596,387 patent/US5869270A/en not_active Expired - Lifetime
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1997
- 1997-01-30 AU AU22538/97A patent/AU729672B2/en not_active Ceased
- 1997-01-30 JP JP09527863A patent/JP2000515363A/ja active Pending
- 1997-01-30 EP EP04019176A patent/EP1526141A3/en not_active Withdrawn
- 1997-01-30 WO PCT/US1997/001617 patent/WO1997028191A1/en not_active Ceased
- 1997-01-30 DE DE69730693T patent/DE69730693T2/de not_active Expired - Lifetime
- 1997-01-30 EP EP97905709A patent/EP0877760B1/en not_active Expired - Lifetime
- 1997-01-30 CA CA002244755A patent/CA2244755A1/en not_active Abandoned
- 1997-01-30 DK DK97905709T patent/DK0877760T3/da active
- 1997-01-30 AT AT97905709T patent/ATE276275T1/de not_active IP Right Cessation
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1998
- 1998-04-28 US US09/067,615 patent/US6309645B1/en not_active Expired - Lifetime
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2001
- 2001-05-03 US US09/848,164 patent/US7141656B2/en not_active Expired - Fee Related
Cited By (42)
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Also Published As
| Publication number | Publication date |
|---|---|
| ATE276275T1 (de) | 2004-10-15 |
| WO1997028191A1 (en) | 1997-08-07 |
| DE69730693D1 (de) | 2004-10-21 |
| CA2244755A1 (en) | 1997-08-07 |
| US6309645B1 (en) | 2001-10-30 |
| DE69730693T2 (de) | 2005-10-06 |
| US5869270A (en) | 1999-02-09 |
| AU729672B2 (en) | 2001-02-08 |
| EP0877760A1 (en) | 1998-11-18 |
| EP0877760A4 (enExample) | 1998-12-30 |
| DK0877760T3 (da) | 2004-12-20 |
| US20020034513A1 (en) | 2002-03-21 |
| EP1526141A2 (en) | 2005-04-27 |
| EP0877760B1 (en) | 2004-09-15 |
| EP1526141A3 (en) | 2005-08-24 |
| AU2253897A (en) | 1997-08-22 |
| US7141656B2 (en) | 2006-11-28 |
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