JP2001514483A - 核酸増幅法:分枝―伸長増幅方法(ram) - Google Patents
核酸増幅法:分枝―伸長増幅方法(ram)Info
- Publication number
- JP2001514483A JP2001514483A JP50912298A JP50912298A JP2001514483A JP 2001514483 A JP2001514483 A JP 2001514483A JP 50912298 A JP50912298 A JP 50912298A JP 50912298 A JP50912298 A JP 50912298A JP 2001514483 A JP2001514483 A JP 2001514483A
- Authority
- JP
- Japan
- Prior art keywords
- probe
- amplification
- nucleic acid
- target nucleic
- complementary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6862—Ligase chain reaction [LCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/690,494 | 1996-07-31 | ||
| US08/690,494 US5942391A (en) | 1994-06-22 | 1996-07-31 | Nucleic acid amplification method: ramification-extension amplification method (RAM) |
| PCT/US1997/013391 WO1998004746A1 (en) | 1996-07-31 | 1997-07-30 | Nucleic acid amplification method: ramification-extension amplification method (ram) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001514483A true JP2001514483A (ja) | 2001-09-11 |
| JP2001514483A5 JP2001514483A5 (enExample) | 2005-04-07 |
Family
ID=24772690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50912298A Pending JP2001514483A (ja) | 1996-07-31 | 1997-07-30 | 核酸増幅法:分枝―伸長増幅方法(ram) |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US5942391A (enExample) |
| EP (1) | EP0915991B1 (enExample) |
| JP (1) | JP2001514483A (enExample) |
| AT (1) | ATE339515T1 (enExample) |
| DE (1) | DE69736668T2 (enExample) |
| ES (1) | ES2273371T3 (enExample) |
| WO (1) | WO1998004746A1 (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007063807A1 (ja) * | 2005-11-29 | 2007-06-07 | Olympus Corporation | 核酸の一次構造変化の解析方法 |
| JP2007517525A (ja) * | 2004-01-07 | 2007-07-05 | サード・ウェーブ・テクノロジーズ・インク | C型肝炎ウイルスの遺伝子型の決定方法 |
| JP2008527979A (ja) * | 2005-01-12 | 2008-07-31 | アプレラ コーポレイション | 核酸の選択的増幅のための組成物、方法およびキット |
| JP2013539973A (ja) * | 2010-09-27 | 2013-10-31 | ナブシス, インコーポレイテッド | ニッキングエンドヌクレアーゼを用いるアッセイ方法 |
| JP2019531747A (ja) * | 2016-10-19 | 2019-11-07 | ジェン−プローブ・インコーポレーテッド | C型肝炎ウイルスを検出または定量するための組成物および方法 |
Families Citing this family (259)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994003624A1 (en) * | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
| US6261808B1 (en) * | 1992-08-04 | 2001-07-17 | Replicon, Inc. | Amplification of nucleic acid molecules via circular replicons |
| US7135312B2 (en) | 1993-04-15 | 2006-11-14 | University Of Rochester | Circular DNA vectors for synthesis of RNA and DNA |
| US20070269799A9 (en) * | 1994-06-22 | 2007-11-22 | Zhang David Y | Nucleic acid amplification methods |
| US6593086B2 (en) | 1996-05-20 | 2003-07-15 | Mount Sinai School Of Medicine Of New York University | Nucleic acid amplification methods |
| US5942391A (en) * | 1994-06-22 | 1999-08-24 | Mount Sinai School Of Medicine | Nucleic acid amplification method: ramification-extension amplification method (RAM) |
| USRE43097E1 (en) | 1994-10-13 | 2012-01-10 | Illumina, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
| US6143495A (en) * | 1995-11-21 | 2000-11-07 | Yale University | Unimolecular segment amplification and sequencing |
| US5854033A (en) * | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| WO1997020948A1 (en) | 1995-12-05 | 1997-06-12 | Koch Joern Erland | A cascade nucleic acid amplification reaction |
| US20020150921A1 (en) * | 1996-02-09 | 2002-10-17 | Francis Barany | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
| US6852487B1 (en) * | 1996-02-09 | 2005-02-08 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
| EP0912761A4 (en) * | 1996-05-29 | 2004-06-09 | Cornell Res Foundation Inc | DETERMINATION OF DIFFERENCES IN THE NUCLEIC ACID SEQUENCE BY MEANS OF A COMBINATION OF LIGASE DETERMINATION AND POLYMERASE CHAIN REACTION |
| US20040229221A1 (en) * | 1997-05-08 | 2004-11-18 | Trustees Of Columbia University In The City Of New York | Method to detect mutations in a nucleic acid using a hybridization-ligation procedure |
| JP4294740B2 (ja) | 1997-05-23 | 2009-07-15 | ソレクサ・インコーポレイテッド | 分析物の系列的プロセシングのためのシステムおよび装置 |
| KR100718028B1 (ko) * | 1998-03-04 | 2007-05-16 | 악조 노벨 엔.브이. | 엡스타인 바르 바이러스(ebv) 핵산의 증폭 및 검출용 올리고뉴클레오티드 |
| WO1999049079A1 (en) * | 1998-03-25 | 1999-09-30 | Ulf Landegren | Rolling circle replication of padlock probes |
| US8063190B2 (en) * | 1998-06-02 | 2011-11-22 | Tom Robin Caine Boyde | Nucleic acid-linked conjugates and methods for making and using them |
| AU754952B2 (en) | 1998-06-24 | 2002-11-28 | Illumina, Inc. | Decoding of array sensors with microspheres |
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| EP1098996A1 (en) * | 1998-07-20 | 2001-05-16 | Yale University | Method for detecting nucleic acids using target-mediated ligation of bipartite primers |
| WO2000009738A1 (en) * | 1998-08-17 | 2000-02-24 | Packard Bioscience Company | Rolling circle-based analysis of polynucleotide sequence |
| JP3267576B2 (ja) * | 1998-11-09 | 2002-03-18 | 三光純薬株式会社 | プローブ高分子の形成方法 |
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| US7033753B1 (en) | 1999-01-15 | 2006-04-25 | University Of Rochester | Compositions and methods for nonenzymatic ligation of oligonucleotides and detection of genetic polymorphisms |
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- 1997-07-30 ES ES97935208T patent/ES2273371T3/es not_active Expired - Lifetime
- 1997-07-30 EP EP97935208A patent/EP0915991B1/en not_active Expired - Lifetime
- 1997-07-30 AT AT97935208T patent/ATE339515T1/de not_active IP Right Cessation
- 1997-07-30 WO PCT/US1997/013391 patent/WO1998004746A1/en not_active Ceased
- 1997-07-30 DE DE69736668T patent/DE69736668T2/de not_active Expired - Lifetime
-
1999
- 1999-04-23 US US09/299,217 patent/US6569647B1/en not_active Expired - Lifetime
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2002
- 2002-12-04 US US10/309,438 patent/US6855523B2/en not_active Expired - Lifetime
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007517525A (ja) * | 2004-01-07 | 2007-07-05 | サード・ウェーブ・テクノロジーズ・インク | C型肝炎ウイルスの遺伝子型の決定方法 |
| US8071750B2 (en) | 2004-01-07 | 2011-12-06 | Third Wave Technologies, Inc. | Determination of hepatitis C virus genotype |
| JP2008527979A (ja) * | 2005-01-12 | 2008-07-31 | アプレラ コーポレイション | 核酸の選択的増幅のための組成物、方法およびキット |
| WO2007063807A1 (ja) * | 2005-11-29 | 2007-06-07 | Olympus Corporation | 核酸の一次構造変化の解析方法 |
| JP2013539973A (ja) * | 2010-09-27 | 2013-10-31 | ナブシス, インコーポレイテッド | ニッキングエンドヌクレアーゼを用いるアッセイ方法 |
| JP2019531747A (ja) * | 2016-10-19 | 2019-11-07 | ジェン−プローブ・インコーポレーテッド | C型肝炎ウイルスを検出または定量するための組成物および方法 |
| JP2022022452A (ja) * | 2016-10-19 | 2022-02-03 | ジェン-プローブ・インコーポレーテッド | C型肝炎ウイルスを検出または定量するための組成物および方法 |
| JP7167013B2 (ja) | 2016-10-19 | 2022-11-08 | ジェン-プローブ・インコーポレーテッド | C型肝炎ウイルスを検出または定量するための組成物および方法 |
| JP7469286B2 (ja) | 2016-10-19 | 2024-04-16 | ジェン-プローブ・インコーポレーテッド | C型肝炎ウイルスを検出または定量するための組成物および方法 |
| US12492437B2 (en) | 2016-10-19 | 2025-12-09 | Gen-Probe Incorporated | Compositions and methods for detecting or quantifying hepatitis C virus |
Also Published As
| Publication number | Publication date |
|---|---|
| DE69736668T2 (de) | 2007-09-13 |
| EP0915991A1 (en) | 1999-05-19 |
| EP0915991B1 (en) | 2006-09-13 |
| US5942391A (en) | 1999-08-24 |
| ATE339515T1 (de) | 2006-10-15 |
| EP0915991A4 (en) | 2002-10-25 |
| US20030190604A1 (en) | 2003-10-09 |
| US6569647B1 (en) | 2003-05-27 |
| DE69736668D1 (de) | 2006-10-26 |
| US6855523B2 (en) | 2005-02-15 |
| ES2273371T3 (es) | 2007-05-01 |
| WO1998004746A1 (en) | 1998-02-05 |
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