|
WO1996025157A1
(en)
*
|
1995-02-17 |
1996-08-22 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
US5807876A
(en)
|
1996-04-23 |
1998-09-15 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of IMPDH enzyme
|
|
US6054472A
(en)
*
|
1996-04-23 |
2000-04-25 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of IMPDH enzyme
|
|
US6211373B1
(en)
*
|
1996-03-20 |
2001-04-03 |
Smithkline Beecham Corporation |
Phenyl urea antagonists of the IL-8 receptor
|
|
ATE209192T1
(de)
*
|
1996-05-20 |
2001-12-15 |
Teijin Ltd |
Cyclischer diarylalkyl diaminederivate als antogoniste von chemokinerezeptoren
|
|
WO1997049399A1
(en)
*
|
1996-06-27 |
1997-12-31 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
JP2000515554A
(ja)
|
1996-08-06 |
2000-11-21 |
スミスクライン・ビーチャム・コーポレイション |
Il―8受容体アンタゴニスト
|
|
JP2001523220A
(ja)
*
|
1996-08-06 |
2001-11-20 |
スミスクライン・ビーチャム・コーポレイション |
Il―8受容体アンタゴニスト
|
|
JP2000516620A
(ja)
*
|
1996-08-15 |
2000-12-12 |
スミスクライン・ビーチャム・コーポレイション |
Il―8レセプターアンタゴニスト
|
|
CA2268085A1
(en)
*
|
1996-10-22 |
1998-04-30 |
Go Wakabayashi |
Sepsis remedy comprising anti-il-8 antibody as active ingredient
|
|
DE19651040C2
(de)
*
|
1996-12-09 |
1999-01-28 |
Bayer Ag |
Verfahren zur Herstellung von 2-Amino-5-alkyl-phenolen
|
|
US6300325B1
(en)
*
|
1997-01-23 |
2001-10-09 |
Smithkline Beecham Corporation |
IL-8 receptor antagonists
|
|
US6436927B1
(en)
|
1997-02-12 |
2002-08-20 |
Smithkline Beecham Corporation |
IL-8 receptor antagonists
|
|
EP0971908B1
(en)
*
|
1997-02-12 |
2004-06-30 |
SmithKline Beecham Corporation |
Il-8 receptor antagonists
|
|
US6696475B2
(en)
|
1997-04-22 |
2004-02-24 |
Neurosearch A/S |
Substituted phenyl derivatives, their preparation and use
|
|
US6344476B1
(en)
*
|
1997-05-23 |
2002-02-05 |
Bayer Corporation |
Inhibition of p38 kinase activity by aryl ureas
|
|
EP1014962A4
(en)
*
|
1997-06-26 |
2007-06-27 |
Lilly Co Eli |
ANTITHROMBOTIC AGENTS
|
|
WO1999006354A1
(en)
*
|
1997-07-29 |
1999-02-11 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
US7067117B1
(en)
|
1997-09-11 |
2006-06-27 |
Cambridge University Technical Services, Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
US6989435B2
(en)
|
1997-09-11 |
2006-01-24 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
AU2003204708B2
(en)
*
|
1997-12-22 |
2006-05-25 |
Bayer Healthcare Llc |
Inhibition of Raf Kinase using Substituted Heterocyclic Ureas
|
|
CA2315717C
(en)
*
|
1997-12-22 |
2011-02-01 |
Bayer Corporation |
Inhibition of raf kinase using substituted heterocyclic ureas
|
|
US7329670B1
(en)
|
1997-12-22 |
2008-02-12 |
Bayer Pharmaceuticals Corporation |
Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
|
|
US7517880B2
(en)
*
|
1997-12-22 |
2009-04-14 |
Bayer Pharmaceuticals Corporation |
Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
|
|
DE1049664T1
(de)
*
|
1997-12-22 |
2001-05-03 |
Bayer Corp., Pittsburgh |
Hemmung der raf-kinase unter verwendung von symmetrisch und unsymmetrisch substituierten harnstoffen
|
|
US20080300281A1
(en)
*
|
1997-12-22 |
2008-12-04 |
Jacques Dumas |
Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas
|
|
CA2335292A1
(en)
*
|
1998-06-17 |
1999-12-23 |
Katherine Lousia Widdowson |
Il-8 receptor antagonists
|
|
CN1314893A
(zh)
*
|
1998-07-23 |
2001-09-26 |
史密丝克莱恩比彻姆公司 |
Il-8受体拮抗剂
|
|
EP1107948A4
(en)
*
|
1998-08-28 |
2002-01-02 |
Smithkline Beecham |
IMPROVED SYNTHESIS OF 3-HYDROXY-4-AMINO-BENZONITRILE
|
|
HUP0103673A3
(en)
|
1998-10-22 |
2003-03-28 |
Neurosearch As |
Substituted phenyl derivatives, their preparation and use
|
|
US6335350B1
(en)
|
1998-12-09 |
2002-01-01 |
American Home Products Corporation |
Acetamide and substituted acetamide-containing thiourea inhibitors of herpes viruses
|
|
US6262090B1
(en)
|
1998-12-09 |
2001-07-17 |
American Home Products Corporation |
Aminopyridine-containing thiourea inhibitors of herpes viruses
|
|
US6255349B1
(en)
|
1998-12-09 |
2001-07-03 |
American Home Products Corporation |
Alph-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group
|
|
ATE267824T1
(de)
*
|
1998-12-09 |
2004-06-15 |
Wyeth Corp |
Alpha-methylbenzyl-enthaltende thioharnstoffe als inhibitoren von herpes-viren mit einer phenylenediamingruppe
|
|
US6197803B1
(en)
|
1998-12-09 |
2001-03-06 |
American Home Products Corporation |
Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group
|
|
US6166028A
(en)
|
1998-12-09 |
2000-12-26 |
American Home Products Corporation |
Diaminopuridine-containing thiourea inhibitors of herpes viruses
|
|
US6201013B1
(en)
|
1998-12-09 |
2001-03-13 |
American Home Products Corporation |
Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing a substituted phenylenediamine group
|
|
CN1332725A
(zh)
*
|
1998-12-09 |
2002-01-23 |
美国家庭用品有限公司 |
疱疹病毒的硫脲抑制剂
|
|
US6207715B1
(en)
|
1998-12-09 |
2001-03-27 |
American Home Products Corporation |
Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a substituted phenylene-diamine group
|
|
US20080269265A1
(en)
*
|
1998-12-22 |
2008-10-30 |
Scott Miller |
Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas
|
|
WO2000041698A1
(en)
*
|
1999-01-13 |
2000-07-20 |
Bayer Corporation |
φ-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS
|
|
RU2319693C9
(ru)
*
|
1999-01-13 |
2008-08-20 |
Байер Копэрейшн |
Производные мочевины (варианты), фармацевтическая композиция (варианты) и способ лечения заболевания, связанного с ростом раковых клеток (варианты)
|
|
EP1140840B1
(en)
*
|
1999-01-13 |
2006-03-22 |
Bayer Pharmaceuticals Corp. |
-g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
US7928239B2
(en)
|
1999-01-13 |
2011-04-19 |
Bayer Healthcare Llc |
Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
|
|
UA73492C2
(en)
|
1999-01-19 |
2005-08-15 |
|
Aromatic heterocyclic compounds as antiinflammatory agents
|
|
MXPA01008440A
(es)
|
1999-02-22 |
2002-04-24 |
Boehringer Ingelheim Pharma |
Derivados heterociclicos policiclos como agentes anti-inflamatorios..
|
|
JP2002539206A
(ja)
|
1999-03-12 |
2002-11-19 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
抗炎症剤としての芳香族複素環化合物
|
|
HK1043127B
(zh)
|
1999-03-12 |
2004-12-24 |
贝林格尔‧英格海姆药物公司 |
作为消炎剂的化合物
|
|
ATE303357T1
(de)
*
|
1999-03-17 |
2005-09-15 |
|
Amid-derivate
|
|
CO5170528A1
(es)
*
|
1999-05-28 |
2002-06-27 |
Smithkline Beecham Corp |
Antagonistas de los receptores de la il-8 nistas del recpetor de la il-8
|
|
CO5190710A1
(es)
*
|
1999-06-15 |
2002-08-29 |
Smithkline Beecham Corp |
Antagonistas de un receptor de il-8 un receptor de il-8
|
|
CO5200760A1
(es)
*
|
1999-06-16 |
2002-09-27 |
Smithkline Beecham Corp |
Antagonistas del receptor de la il-8 ceptor il-8
|
|
DE60036812T2
(de)
*
|
1999-07-07 |
2008-07-17 |
Astrazeneca Uk Ltd. |
Chinazolin derivate
|
|
ATE312823T1
(de)
|
1999-07-09 |
2005-12-15 |
Boehringer Ingelheim Pharma |
Verfahren zur herstellung heteroarylsubstituierter ureaverbindungen
|
|
CA2380389A1
(en)
|
1999-07-26 |
2001-02-01 |
Banyu Pharmaceutical Co., Ltd. |
Biarylurea derivatives
|
|
CO5271663A1
(es)
*
|
1999-11-09 |
2003-04-30 |
Smithkline Beecham Corp |
Antagonistas del receptor il-8
|
|
DE60036726T2
(de)
|
1999-11-16 |
2008-02-07 |
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield |
Harnstoff derivate als entzündungshemmende mittel
|
|
US6525046B1
(en)
|
2000-01-18 |
2003-02-25 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Aromatic heterocyclic compounds as antiinflammatory agents
|
|
US6608052B2
(en)
|
2000-02-16 |
2003-08-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Compounds useful as anti-inflammatory agents
|
|
EP1274413A4
(en)
*
|
2000-03-01 |
2005-08-10 |
Smithkline Beecham Corp |
IL-8 RECEPTOR ANTAGONISTS
|
|
WO2001068033A2
(en)
*
|
2000-03-10 |
2001-09-20 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
MY133845A
(en)
*
|
2000-03-10 |
2007-11-30 |
Smithkline Beecham Corp |
Il-8 receptor antagonists
|
|
WO2001068569A2
(en)
*
|
2000-03-14 |
2001-09-20 |
Smithkline Beecham Corporation |
Il-8 receptor antagonists
|
|
AR031098A1
(es)
*
|
2000-03-16 |
2003-09-10 |
Smithkline Beecham Corp |
Compuestos de hidroxifenil urea sustituidos con sulfonamidas, composiciones farmaceuticas que los comprenden, y uso de los mismos en la fabricacion de medicamentos para tratar una enfermedad mediada por una quimioquina
|
|
UY26627A1
(es)
*
|
2000-03-24 |
2001-09-28 |
Smithkline Beecham Corp |
Antagonistas de receptores de il-8
|
|
CA2405690A1
(en)
*
|
2000-04-14 |
2002-10-09 |
Kureha Chemical Industry Company, Limited |
Nitrogen-containing compounds and antiviral drugs containing the same
|
|
AU2001266640A1
(en)
|
2000-05-30 |
2001-12-11 |
Smithkline Beecham Corporation |
IL-8 receptor antagonists
|
|
MXPA03000500A
(es)
*
|
2000-07-18 |
2003-06-24 |
Smithkline Beecham Corp |
Uso de antagonistas del receptor de isoleucina 8 en el tratamiento de infecciones por virus.
|
|
WO2002022565A1
(en)
*
|
2000-09-15 |
2002-03-21 |
Iconix Pharmaceuticals, Inc. |
Inhibitors of rho c
|
|
US7235576B1
(en)
|
2001-01-12 |
2007-06-26 |
Bayer Pharmaceuticals Corporation |
Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
AR032398A1
(es)
*
|
2001-01-16 |
2003-11-05 |
Smithkline Beecham Corp |
Compuesto de escuaramida de sulfonamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar dicha composicion
|
|
US20040132694A1
(en)
*
|
2001-01-16 |
2004-07-08 |
Palovich Michael R. |
Il-8 receptor antagonists
|
|
EP1395548A1
(en)
|
2001-02-26 |
2004-03-10 |
4Sc Ag |
Derivatives of diphenylurea, diphenyloxalic acid diamide and diphenylsulfuric acid diamide and their use as medicaments
|
|
DE10109204A1
(de)
*
|
2001-02-26 |
2002-09-19 |
4Sc Ag |
Verbindungen zur Behandlung von Protozoen-Erkrankungen
|
|
ITMI20010395A1
(it)
|
2001-02-27 |
2002-08-27 |
Dompe Spa |
Omega-amminoalchilammidi di acidi r-2-aril-propionici come inibitori della chemiotassi di cellule polimorfonucleate e mononucleate
|
|
EP1379508B9
(en)
|
2001-02-28 |
2011-02-09 |
Temple University - Of The Commonwealth System of Higher Education |
N-(aryl)-2-arylethenesulfonamides and therapeutic uses thereof
|
|
US7371763B2
(en)
*
|
2001-04-20 |
2008-05-13 |
Bayer Pharmaceuticals Corporation |
Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
|
|
WO2002094261A1
(fr)
*
|
2001-05-24 |
2002-11-28 |
Kureha Chemical Industry Company, Limited |
Medicaments antagonistes de cxcr4 comprenant un compose contenant de l'azote
|
|
US20040038854A1
(en)
*
|
2001-07-16 |
2004-02-26 |
Dillon Susan B. |
Use of il-8 receptor antagonists in the treatment of virus infections
|
|
US6791892B2
(en)
*
|
2001-07-18 |
2004-09-14 |
Samsung Electronics Co., Ltd. |
Method of generating an initializing signal during power-up of semiconductor memory device
|
|
SI2305255T1
(sl)
*
|
2001-12-03 |
2012-10-30 |
Bayer Healthcare Llc |
Arilsečninske spojine v kombinaciji z drugimi citostatičnimi ali citotoksičnimi sredstvi za zdravljenje človeških rakov
|
|
US20080108672A1
(en)
*
|
2002-01-11 |
2008-05-08 |
Bernd Riedl |
Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
|
|
WO2003068228A1
(en)
*
|
2002-02-11 |
2003-08-21 |
Bayer Pharmaceuticals Corporation |
Aryl ureas with angiogenesis inhibiting activity
|
|
CN1318404C
(zh)
*
|
2002-02-11 |
2007-05-30 |
拜耳制药公司 |
作为激酶抑制剂的芳基脲类化合物
|
|
AU2003209119A1
(en)
*
|
2002-02-11 |
2003-09-04 |
Bayer Pharmaceuticals Corporation |
Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors
|
|
US20040023961A1
(en)
*
|
2002-02-11 |
2004-02-05 |
Bayer Corporation |
Aryl ureas with raf kinase and angiogenisis inhibiting activity
|
|
ES2299689T3
(es)
|
2002-02-25 |
2008-06-01 |
Boehringer Ingelheim Pharmaceuticals Inc. |
Compuestos de cicloalquil-uera fusionada con benzo 1,4-disustituido, utiles para el tratamiento de enfermedades por citoquinas.
|
|
WO2003072063A2
(en)
*
|
2002-02-28 |
2003-09-04 |
Temple University - Of The Commonwealth System Of Higher Education |
Amino-substituted sulfonanilides and derivatives thereof for treating proliferative disorders
|
|
KR20030080509A
(ko)
*
|
2002-04-09 |
2003-10-17 |
주식회사 엘지생명과학 |
우레아, 티오우레아 및 설파마이드 유도체를 함유하는항균제 조성물
|
|
US20030236287A1
(en)
*
|
2002-05-03 |
2003-12-25 |
Piotrowski David W. |
Positive allosteric modulators of the nicotinic acetylcholine receptor
|
|
MXPA05001235A
(es)
*
|
2002-08-01 |
2005-06-08 |
Neurosearch As |
Compuestos utiles para el tratamiento de enfermedades sensibles a la terapia antiangiogenetica.
|
|
JP3714948B2
(ja)
*
|
2002-09-11 |
2005-11-09 |
呉羽化学工業株式会社 |
アミン化合物及びその用途
|
|
EP1402887A1
(en)
*
|
2002-09-18 |
2004-03-31 |
Jerini AG |
New compounds for the inhibition of undesired cell proliferation and use thereof
|
|
TW200418812A
(en)
|
2002-10-29 |
2004-10-01 |
Smithkline Beecham Corp |
IL-8 receptor antagonists
|
|
DE10251830A1
(de)
*
|
2002-11-07 |
2004-05-19 |
Wella Ag |
2-Amino-5-ethylphenol enthaltendes Mittel zum Färben von Keratinfasern
|
|
MXPA05005409A
(es)
|
2002-11-21 |
2005-08-03 |
Neurosearch As |
Derivados de arilureido y su uso medico.
|
|
WO2004058683A2
(en)
*
|
2002-12-20 |
2004-07-15 |
Migenix Corp. |
Ligands of adenine nucleotide translocase (ant) and compositions and methods related thereto
|
|
US20060229335A1
(en)
*
|
2002-12-24 |
2006-10-12 |
Bradley Teegarden |
Diarylamine and arylheteroarylamine pyrazole derivatives as modulators of 5ht2a
|
|
US7220768B2
(en)
*
|
2003-02-11 |
2007-05-22 |
Wyeth Holdings Corp. |
Isoxazole-containing thiourea inhibitors useful for treatment of varicella zoster virus
|
|
NZ562410A
(en)
*
|
2003-02-21 |
2009-02-28 |
Resmed Ltd |
Nasal pillow mask assembly
|
|
US7557129B2
(en)
|
2003-02-28 |
2009-07-07 |
Bayer Healthcare Llc |
Cyanopyridine derivatives useful in the treatment of cancer and other disorders
|
|
EP1457485A1
(en)
*
|
2003-03-14 |
2004-09-15 |
Dompé S.P.A. |
Sulfonic acids, their derivatives and pharmaceutical compositions containing them
|
|
EP1608319A4
(en)
*
|
2003-04-03 |
2007-02-28 |
Univ California |
IMPROVED HEMMER FOR SOLUBLE EPOXY HYDROLASE
|
|
DE602004007382T2
(de)
|
2003-05-20 |
2008-04-17 |
Bayer Pharmaceuticals Corp., West Haven |
Diaryl-harnstoffe für durch pdgfr vermittelte krankheiten
|
|
MY141862A
(en)
|
2003-07-22 |
2010-07-16 |
Arena Pharm Inc |
Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related thereto
|
|
NZ544920A
(en)
|
2003-07-23 |
2009-11-27 |
Bayer Healthcare Llc |
4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyridine-2-carboxylic acid methylamide and metabolites for the treatment and prevention of diseases and conditions
|
|
WO2005023238A1
(en)
*
|
2003-09-04 |
2005-03-17 |
Poseidon Pharmaceuticals A/S |
Erg channel openers for the treatment of hyperexcitability-related neuronal diseases
|
|
EP1663192B1
(en)
|
2003-09-04 |
2008-12-03 |
NeuroSearch A/S |
hERG1 CHANNEL OPENERS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS
|
|
TW200530236A
(en)
|
2004-02-23 |
2005-09-16 |
Chugai Pharmaceutical Co Ltd |
Heteroaryl phenylurea
|
|
EP1724263B1
(en)
*
|
2004-03-10 |
2014-03-05 |
Kureha Corporation |
Basic amine compound and use thereof
|
|
US20090018092A1
(en)
|
2004-03-16 |
2009-01-15 |
The Regents Of The University Of California |
Reducing Nephropathy with Inhibitors of Soluble Epoxide Hydrolase and Epoxyeicosanoids
|
|
EP1727803B3
(en)
*
|
2004-03-23 |
2014-04-23 |
Arena Pharmaceuticals, Inc. |
Processes for preparing substituted n-aryl-n'-[3-(1h-pyrazol-5-yl)phenyl] ureas and intermediates thereof
|
|
RU2006131454A
(ru)
*
|
2004-03-29 |
2008-05-10 |
Ньюросерч А/С (DK) |
Новые производные мочевины и их медицинское применение
|
|
WO2005110994A2
(en)
|
2004-04-30 |
2005-11-24 |
Bayer Pharmaceuticals Corporation |
Substituted pyrazolyl urea derivatives useful in the treatment of cancer
|
|
ES2340179T3
(es)
*
|
2004-05-12 |
2010-05-31 |
Bristol-Myers Squibb Company |
Antagonistas de urea del receptor p2y1 utiles en el tratamiento de afecciones tromboticas.
|
|
US7550499B2
(en)
|
2004-05-12 |
2009-06-23 |
Bristol-Myers Squibb Company |
Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
US7326729B2
(en)
*
|
2004-05-12 |
2008-02-05 |
Schering Corporation |
CXCR1 and CXCR2 chemokine antagonists
|
|
FR2872159B1
(fr)
*
|
2004-06-28 |
2007-10-05 |
Merck Sante Soc Par Actions Si |
Nouveaux derives acides carboxyliques phenyliques et leur utilisation dans le traitement du diabete
|
|
JP4084836B2
(ja)
|
2004-08-12 |
2008-04-30 |
ファイザー・インク |
p38MAPキナーゼインヒビターとしてのトリアゾロピリジニルスルファニル誘導体
|
|
EP1634573A1
(en)
*
|
2004-08-16 |
2006-03-15 |
The Procter and Gamble Company |
2-(Amino or substituted Amino)-5,6-substituted Phenol compounds, dyeing compositions containing them, and use thereof
|
|
BRPI0514379A
(pt)
*
|
2004-08-16 |
2008-06-10 |
Procter & Gamble |
compostos de 2-(amino ou amino substituìdo) fenol-5, 6-substituìdo, composições para tingimento contendo os mesmos, e uso das mesmas
|
|
EP1814875A4
(en)
*
|
2004-10-20 |
2010-02-17 |
Univ California |
IMPROVED INHIBITORS OF SOLUBLE EPOXY HYDROLASE
|
|
US20070249625A1
(en)
*
|
2004-10-20 |
2007-10-25 |
Jakob Busch-Petersen |
Il-8 Receptor Antagonists
|
|
EP1809619A1
(en)
|
2004-10-21 |
2007-07-25 |
Transtech Pharma, Inc. |
Bissulfonamide compounds as agonists of galr1, compositions, and methods of use
|
|
PE20061130A1
(es)
*
|
2004-11-19 |
2007-01-05 |
Arena Pharm Inc |
Derivados de 3-fenil-pirazol como moduladores del receptor de serotonina 5-ht2a
|
|
WO2006060762A2
(en)
*
|
2004-12-03 |
2006-06-08 |
Arena Pharmaceuticals, Inc. |
Pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
|
|
EP1843762A1
(en)
*
|
2005-01-19 |
2007-10-17 |
Arena Pharmaceuticals, Inc. |
Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis or treatment of progressive multifocal leukoencephalopathy
|
|
US7645778B2
(en)
|
2005-01-19 |
2010-01-12 |
Bristol-Myers Squibb Company |
Heteroaryl compounds as P2Y1 receptor inhibitors
|
|
EP1864136A1
(en)
*
|
2005-03-23 |
2007-12-12 |
AstraZeneca AB |
Screen
|
|
US7816382B2
(en)
|
2005-06-27 |
2010-10-19 |
Bristol-Myers Squibb Company |
Linear urea mimics antagonists of P2Y1 receptor useful in the treatment of thrombotic condition
|
|
US7728008B2
(en)
|
2005-06-27 |
2010-06-01 |
Bristol-Myers Squibb Company |
N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
EP1899299B1
(en)
|
2005-06-27 |
2010-10-20 |
Bristol-Myers Squibb Company |
C-linked cyclic antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
|
|
US7714002B2
(en)
|
2005-06-27 |
2010-05-11 |
Bristol-Myers Squibb Company |
Carbocycle and heterocycle antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
GB0526255D0
(en)
|
2005-12-22 |
2006-02-01 |
Novartis Ag |
Organic compounds
|
|
WO2007087441A2
(en)
*
|
2006-01-25 |
2007-08-02 |
Synta Pharmaceuticals Corp. |
Substituted aromatic compounds for inflammation and immune-related uses
|
|
TWI414517B
(zh)
*
|
2006-04-21 |
2013-11-11 |
Smithkline Beecham Corp |
Il-8受體拮抗劑
|
|
CN101495113A
(zh)
*
|
2006-04-21 |
2009-07-29 |
史密丝克莱恩比彻姆公司 |
Il-8受体拮抗剂
|
|
WO2007127930A2
(en)
*
|
2006-04-28 |
2007-11-08 |
Kansas State University Research Foundation |
Compounds affecting gap junction activity
|
|
USRE45337E1
(en)
|
2006-05-18 |
2015-01-13 |
Arena Pharmaceuticals, Inc. |
Ethers, secondary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
|
|
WO2007136703A1
(en)
|
2006-05-18 |
2007-11-29 |
Arena Pharmaceuticals, Inc. |
Primary amines and derivatives thereof as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
|
|
AU2007254255B2
(en)
|
2006-05-18 |
2013-03-07 |
Arena Pharmaceuticals, Inc. |
Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-HT2A serotonin receptor
|
|
CL2007001829A1
(es)
|
2006-06-23 |
2008-01-25 |
Smithkline Beecham Corp |
P-toluensulfonato de n-[4-cloro-2-hidroxi-3-(piperazina-1-sulfonil)fenil]-n-(2-cloro-3-fluorofenil)urea;procedimiento de preparacion;composicion farmaceutica;combinacion farmaceutica;y uso en el tratamiento de una enfermedad mediada por la quiimioquina il-8, tales como asma y epoc.
|
|
TWI415845B
(zh)
*
|
2006-10-03 |
2013-11-21 |
Arena Pharm Inc |
用於治療與5-ht2a血清素受體相關聯病症之作為5-ht2a血清素受體之調節劑的吡唑衍生物
|
|
US7960569B2
(en)
|
2006-10-17 |
2011-06-14 |
Bristol-Myers Squibb Company |
Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
WO2008047067A1
(en)
*
|
2006-10-20 |
2008-04-24 |
University Court Of The University Of Edinburgh |
Treatment of inflammatory disease
|
|
JP5393677B2
(ja)
|
2007-08-15 |
2014-01-22 |
アリーナ ファーマシューティカルズ, インコーポレイテッド |
5−HT2Aセロトニン受容体に関連した障害の治療のための5−HT2Aセロトニン受容体のモジュレーターとしてのイミダゾ[1,2−a]ピリジン誘導体
|
|
AU2008309003A1
(en)
*
|
2007-09-28 |
2009-04-09 |
Glaxosmithkline Llc |
Glycogen phosphorylase inhibitor compound and pharmaceutical composition thereof
|
|
WO2009123714A2
(en)
|
2008-04-02 |
2009-10-08 |
Arena Pharmaceuticals, Inc. |
Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
|
|
WO2010062321A1
(en)
|
2008-10-28 |
2010-06-03 |
Arena Pharmaceuticals, Inc. |
Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
|
|
EP2364142B1
(en)
|
2008-10-28 |
2018-01-17 |
Arena Pharmaceuticals, Inc. |
Compositions of a 5-ht2a serotonin receptor modulator useful for the treatment of disorders related thereto
|
|
WO2010092440A1
(en)
*
|
2009-02-16 |
2010-08-19 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Cxcr2 receptor antagonists for the treatment or the prevention of insulin resistance
|
|
WO2011022028A2
(en)
*
|
2009-05-18 |
2011-02-24 |
Tufts University |
Small molecule antagonists of phosphatidylinositol-3, 4, 5-triphosphate (pip3) and uses thereof
|
|
WO2011073248A1
(en)
*
|
2009-12-17 |
2011-06-23 |
Galderma Research & Development |
Use of compounds in the treatment or prevention of skin disorders
|
|
WO2011075596A1
(en)
|
2009-12-18 |
2011-06-23 |
Arena Pharmaceuticals, Inc. |
Crystalline forms of certain 3-phenyl-pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
|
|
BRPI1004176A2
(pt)
*
|
2010-10-25 |
2015-08-11 |
Univ Rio De Janeiro |
Compostos aril e/ou hetero aril uréias funcionalizados; processo de síntese desses composto; composição farmacêutica contendo tais compostos e usos
|
|
US8648118B2
(en)
|
2010-12-17 |
2014-02-11 |
Boehringer Ingelheim International Gmbh |
Bicyclic ring system substituted amide functionalised phenols as medicaments
|
|
CA2834548C
(en)
|
2011-04-28 |
2021-06-01 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
|
US9790184B2
(en)
|
2012-07-27 |
2017-10-17 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
|
US9518011B2
(en)
|
2012-11-21 |
2016-12-13 |
Nippon Soda Co., Ltd. |
Recording material produced using non-phenol compound
|
|
US9914717B2
(en)
|
2012-12-20 |
2018-03-13 |
The Broad Institute, Inc. |
Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors
|
|
KR102216666B1
(ko)
*
|
2013-02-13 |
2021-02-17 |
오지 홀딩스 가부시키가이샤 |
감열 기록체
|
|
US9789721B2
(en)
|
2013-05-22 |
2017-10-17 |
Oji Holdings Corporation |
Thermosensitive recording medium
|
|
CA2989343A1
(en)
|
2015-06-12 |
2016-12-15 |
Yandong Wen |
Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of rem sleep behavior disorder
|
|
EP3117835A1
(en)
*
|
2015-07-14 |
2017-01-18 |
Dompé farmaceutici s.p.a. |
Il-8 inhibitors for use in the treatment of certain urological disorders
|
|
RU2018103338A
(ru)
|
2015-07-15 |
2019-08-15 |
Аксовант Сайенсиз Гмбх |
Производные диарил- и арилгетероарилмочевины для профилактики и лечения галлюцинаций, ассоциированных с нейродегенеративным заболеванием
|
|
US10093617B1
(en)
*
|
2015-10-30 |
2018-10-09 |
Sumitomo Chemical Company, Limited |
Method for producing 2-amino-4-substituted phenol
|
|
EP3476829B1
(en)
|
2016-06-22 |
2021-12-15 |
Fudan University |
Biaryl urea derivative or salt thereof, and manufacturing and application of same
|
|
CN107522641B
(zh)
*
|
2016-06-22 |
2020-05-05 |
复旦大学 |
联芳基脲类衍生物或其盐及其制备方法和用途
|
|
JP7252125B2
(ja)
|
2016-10-03 |
2023-04-04 |
ザ チルドレンズ メディカル センター コーポレーション |
糖尿病性腎症の予防および処置
|
|
JP2021510733A
(ja)
|
2018-01-12 |
2021-04-30 |
ケーディーエーシー セラピューティクス,インコーポレーテッドKdac Therapeutics, Inc. |
がんの処置のための選択的ヒストンデアセチラーゼ3(hdac3)インヒビターと免疫治療剤との組み合わせ
|
|
CN110698373A
(zh)
*
|
2019-11-07 |
2020-01-17 |
温州大学 |
N-(2-(甲硫基)苯基)乙酰胺类化合物的制备方法及其净化提纯方法
|
|
CN112321452B
(zh)
*
|
2020-09-11 |
2022-11-29 |
北京红惠新医药科技有限公司 |
厚朴酚衍生物、和厚朴酚衍生物及其盐酸盐、制备方法及应用
|
|
WO2025121190A1
(ja)
*
|
2023-12-08 |
2025-06-12 |
日産化学株式会社 |
重合体、樹脂組成物、液晶配向剤、樹脂被膜及び液晶配向膜
|