|
HU219131B
(hu)
*
|
1991-10-18 |
2001-02-28 |
Monsanto Co. |
Módszer és fungicid készítmény növények torsgombabetegségének gátlására és a hatóanyagok
|
|
SE9703407D0
(sv)
*
|
1997-09-19 |
1997-09-19 |
Astra Ab |
New use
|
|
SE9802073D0
(sv)
|
1998-06-11 |
1998-06-11 |
Astra Ab |
New use
|
|
GB9825554D0
(en)
*
|
1998-11-20 |
1999-01-13 |
Smithkline Beecham Spa |
Novel Compounds
|
|
US7037922B1
(en)
|
2000-03-10 |
2006-05-02 |
Neurogen Corporation |
Aryl fused 2,4-disubstituted pyridines: NK3 receptor ligands
|
|
ATE247652T1
(de)
|
1999-03-29 |
2003-09-15 |
Neurogen Corp |
4-substituierte chinolinderivate als nk-3 und/oder gaba(a) rezeptor liganden
|
|
WO2000064877A1
(en)
*
|
1999-04-26 |
2000-11-02 |
Neurogen Corporation |
2-aminoquinolinecarboxamides: neurokinin receptor ligands
|
|
EP1385839B1
(en)
*
|
2001-04-11 |
2006-02-22 |
GlaxoSmithKline S.p.A. |
3-substituted quinoline-4-carboxamide derivatives as nk-3 and nk-2 receptor antagonists
|
|
WO2002089802A2
(en)
*
|
2001-05-08 |
2002-11-14 |
Schering Corporation |
Use of neurokinin receptor antagonists to treat androgen-dependent diseases
|
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
BR122018074353B8
(pt)
|
2003-01-28 |
2023-05-02 |
Ironwood Pharmaceuticals Inc |
composição farmacêutica, polipeptídeo e métodos para a produção dos mesmos
|
|
GB0303086D0
(en)
*
|
2003-02-11 |
2003-03-19 |
Merck Sharp & Dohme |
New compounds
|
|
GB0419192D0
(en)
|
2004-08-27 |
2004-09-29 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO2006052722A1
(en)
*
|
2004-11-09 |
2006-05-18 |
Smithkline Beecham Corporation |
Glycogen phosphorylase inhibitor compounds and pharmaceutical compositions thereof
|
|
GB0425077D0
(en)
*
|
2004-11-12 |
2004-12-15 |
Smithkline Beecham Corp |
Novel compounds
|
|
GB0515580D0
(en)
|
2005-07-29 |
2005-09-07 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
CN101282961A
(zh)
*
|
2005-08-11 |
2008-10-08 |
阿斯利康(瑞典)有限公司 |
作为nk3受体调节剂的烷基吡啶基喹啉
|
|
AR057130A1
(es)
|
2005-09-21 |
2007-11-14 |
Astrazeneca Ab |
Quinolinas de alquilsulfoxido y una composicion farmaceutica
|
|
TW201018662A
(en)
*
|
2005-12-12 |
2010-05-16 |
Astrazeneca Ab |
Alkylsulphonamide quinolines
|
|
WO2008151257A2
(en)
|
2007-06-04 |
2008-12-11 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
|
US20100305207A1
(en)
*
|
2007-09-28 |
2010-12-02 |
Pierette Banker |
Glycogen phosphorylase inhibitor compound and pharmaceutical composition thereof
|
|
CN101861303A
(zh)
*
|
2007-09-28 |
2010-10-13 |
葛兰素史密丝克莱恩有限责任公司 |
糖原磷酸化酶抑制剂化合物和其药物组合物
|
|
ES2627848T3
(es)
|
2008-06-04 |
2017-07-31 |
Synergy Pharmaceuticals Inc. |
Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
|
|
ES2624828T3
(es)
|
2008-07-16 |
2017-07-17 |
Synergy Pharmaceuticals Inc. |
Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
|
|
CN103819403B
(zh)
|
2008-12-31 |
2017-01-04 |
阿德利克斯公司 |
用于治疗与体液潴留或盐超负荷有关的病症和胃肠道病症的化合物和方法
|
|
WO2018129556A1
(en)
|
2017-01-09 |
2018-07-12 |
Ardelyx, Inc. |
Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
|
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
|
US10376481B2
(en)
|
2012-08-21 |
2019-08-13 |
Ardelyx, Inc. |
Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
|
|
RU2015107019A
(ru)
|
2012-08-21 |
2016-10-10 |
Эрделикс Инк. |
Соединения и способы для ингибирования nhe-опосредованного антипорта в лечении расстройств, ассоциированных с задержкой жидкости или солевой перегрузкой и заболеваний желудочно-кишечного тракта
|
|
EP2968439A2
(en)
|
2013-03-15 |
2016-01-20 |
Synergy Pharmaceuticals Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
|
US9708367B2
(en)
|
2013-03-15 |
2017-07-18 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase and their uses
|
|
CN105392483B
(zh)
|
2013-04-12 |
2019-03-15 |
阿德利克斯公司 |
用于抑制磷酸盐转运的nhe3结合化合物和方法
|
|
BR112015026519A2
(pt)
|
2013-04-19 |
2017-07-25 |
Astrazeneca Ab |
composto antagonista do receptor nk3 (nk3ra) para uso em um método destinado ao tratamento de síndrome do ovário policístico (sop)
|
|
PL3004138T3
(pl)
|
2013-06-05 |
2024-07-29 |
Bausch Health Ireland Limited |
Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
|
|
WO2017072629A1
(en)
|
2015-10-29 |
2017-05-04 |
Cadila Healthcare Limited |
Pharmaceutical combination of nk3 receptor antagonist and biguanides
|
|
EA201991676A1
(ru)
|
2017-01-09 |
2020-01-30 |
Арделикс, Инк. |
Ингибиторы nhe-опосредованного антипорта
|
|
KR20240090875A
(ko)
|
2017-01-09 |
2024-06-21 |
알데릭스, 인코포레이티드 |
위장관 장애를 치료하는 데 유용한 화합물
|