JO3754B1 - أشكال كريستالين لمثبط أنزيم كيناز تيروسين بروتون - Google Patents

أشكال كريستالين لمثبط أنزيم كيناز تيروسين بروتون

Info

Publication number
JO3754B1
JO3754B1 JOP/2013/0168A JOP20130168A JO3754B1 JO 3754 B1 JO3754 B1 JO 3754B1 JO P20130168 A JOP20130168 A JO P20130168A JO 3754 B1 JO3754 B1 JO 3754B1
Authority
JO
Jordan
Prior art keywords
span
rtl
dir
proton
tyrosine kinase
Prior art date
Application number
JOP/2013/0168A
Other languages
Arabic (ar)
English (en)
Inventor
Goldman Erick
D Wirth David
Purro Norbert
Smyth Mark
Original Assignee
Pharmacyclics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49712527&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3754(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacyclics Llc filed Critical Pharmacyclics Llc
Application granted granted Critical
Publication of JO3754B1 publication Critical patent/JO3754B1/ar

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
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    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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    • A—HUMAN NECESSITIES
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Mechanical Engineering (AREA)
  • Composite Materials (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
JOP/2013/0168A 2012-06-04 2013-06-03 أشكال كريستالين لمثبط أنزيم كيناز تيروسين بروتون JO3754B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261655381P 2012-06-04 2012-06-04

Publications (1)

Publication Number Publication Date
JO3754B1 true JO3754B1 (ar) 2021-01-31

Family

ID=49712527

Family Applications (2)

Application Number Title Priority Date Filing Date
JOP/2013/0168A JO3754B1 (ar) 2012-06-04 2013-06-03 أشكال كريستالين لمثبط أنزيم كيناز تيروسين بروتون
JOP/2020/0222A JOP20200222A1 (ar) 2012-06-04 2020-09-09 أشكال كريستالين لمثبط أنزيم كيناز تيروسين بروتون

Family Applications After (1)

Application Number Title Priority Date Filing Date
JOP/2020/0222A JOP20200222A1 (ar) 2012-06-04 2020-09-09 أشكال كريستالين لمثبط أنزيم كيناز تيروسين بروتون

Country Status (35)

Country Link
US (27) US9540382B2 (https=)
EP (2) EP2854859B1 (https=)
JP (10) JP6236071B2 (https=)
KR (8) KR20210033067A (https=)
CN (2) CN110354132A (https=)
AR (2) AR092844A1 (https=)
AU (7) AU2013271918C1 (https=)
BR (1) BR112014030424A8 (https=)
CA (4) CA3015208C (https=)
CL (3) CL2014003306A1 (https=)
CO (1) CO7240408A2 (https=)
CR (1) CR20140558A (https=)
DK (1) DK2854859T3 (https=)
DO (3) DOP2014000274A (https=)
EA (1) EA201492082A1 (https=)
EC (2) ECSP14033163A (https=)
FI (1) FI2854859T3 (https=)
GT (1) GT201400281A (https=)
HK (1) HK1208803A1 (https=)
IL (4) IL315394A (https=)
JO (2) JO3754B1 (https=)
LT (1) LT2854859T (https=)
MA (2) MA41654B2 (https=)
MX (3) MX348290B (https=)
MY (2) MY187999A (https=)
NZ (4) NZ731932A (https=)
PE (3) PE20241581A1 (https=)
PH (3) PH12021552282A1 (https=)
SG (2) SG11201408067YA (https=)
TN (1) TN2014000492A1 (https=)
TW (3) TWI662964B (https=)
UA (2) UA114421C2 (https=)
UY (2) UY34848A (https=)
WO (1) WO2013184572A1 (https=)
ZA (4) ZA202105174B (https=)

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DK2526933T3 (en) 2006-09-22 2015-05-18 Pharmacyclics Inc Inhibitors of Bruton's tyrosine kinase
US20120101114A1 (en) 2007-03-28 2012-04-26 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase
CA2730930C (en) 2008-07-16 2015-01-13 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase for the treatment of solid tumors
US8491927B2 (en) * 2009-12-02 2013-07-23 Nimble Epitech, Llc Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor
CA3007787C (en) 2010-06-03 2020-03-10 Pharmacyclics Llc The use of inhibitors of bruton's tyrosine kinase (btk)
SG10201600077RA (en) 2011-01-11 2016-02-26 Glaxosmithkline Llc Combination
JP2014520863A (ja) 2011-07-13 2014-08-25 ファーマサイクリックス，インク． Ｂｒｕｔｏｎ型チロシンキナーゼの阻害剤
EP3812387A1 (en) 2011-07-21 2021-04-28 Sumitomo Dainippon Pharma Oncology, Inc. Heterocyclic protein kinase inhibitors
IN2014MN01378A (https=) 2011-12-11 2015-07-03 Viamet Pharmaceuticals Inc
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