JO3108B1 - بيرروليدينونات أروماتية مخلطة مندمجة كمثبطات syk - Google Patents

بيرروليدينونات أروماتية مخلطة مندمجة كمثبطات syk

Info

Publication number
JO3108B1
JO3108B1 JOP/2010/0471A JOP20100471A JO3108B1 JO 3108 B1 JO3108 B1 JO 3108B1 JO P20100471 A JOP20100471 A JO P20100471A JO 3108 B1 JO3108 B1 JO 3108B1
Authority
JO
Jordan
Prior art keywords
diseases
fused heteroaromatic
syk inhibitors
disorders
formula
Prior art date
Application number
JOP/2010/0471A
Other languages
Arabic (ar)
English (en)
Inventor
Betty Lam
Benjamin Jones
Nie Zhe
Victoria Feher
Christopher Smith
Qing Dong
Masashi Takahashi
Yasuyoshi Arikawa
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43618073&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3108(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Application granted granted Critical
Publication of JO3108B1 publication Critical patent/JO3108B1/ar

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
JOP/2010/0471A 2009-12-23 2010-12-22 بيرروليدينونات أروماتية مخلطة مندمجة كمثبطات syk JO3108B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28996909P 2009-12-23 2009-12-23
US38696410P 2010-09-27 2010-09-27

Publications (1)

Publication Number Publication Date
JO3108B1 true JO3108B1 (ar) 2017-09-20

Family

ID=43618073

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2010/0471A JO3108B1 (ar) 2009-12-23 2010-12-22 بيرروليدينونات أروماتية مخلطة مندمجة كمثبطات syk

Country Status (42)

Country Link
US (7) US8440689B2 (OSRAM)
EP (4) EP3825316A1 (OSRAM)
JP (7) JP5658274B2 (OSRAM)
KR (1) KR101790255B1 (OSRAM)
CN (1) CN102753548B (OSRAM)
AR (1) AR081797A1 (OSRAM)
AU (1) AU2010333804B2 (OSRAM)
BR (1) BR112012015651B1 (OSRAM)
CA (1) CA2786950C (OSRAM)
CL (1) CL2012001745A1 (OSRAM)
CO (1) CO6592058A2 (OSRAM)
CR (1) CR20120392A (OSRAM)
CY (1) CY1116736T1 (OSRAM)
DK (1) DK2516434T3 (OSRAM)
DO (1) DOP2012000180A (OSRAM)
EA (1) EA021568B1 (OSRAM)
EC (1) ECSP12012057A (OSRAM)
ES (1) ES2545616T3 (OSRAM)
GE (1) GEP20156243B (OSRAM)
HR (1) HRP20150878T1 (OSRAM)
HU (1) HUE025177T2 (OSRAM)
IL (1) IL220509A (OSRAM)
JO (1) JO3108B1 (OSRAM)
MA (1) MA33909B1 (OSRAM)
ME (1) ME02186B (OSRAM)
MX (1) MX2012007402A (OSRAM)
MY (1) MY159257A (OSRAM)
NZ (1) NZ601267A (OSRAM)
PE (1) PE20130188A1 (OSRAM)
PH (1) PH12012501311A1 (OSRAM)
PL (1) PL2516434T3 (OSRAM)
PT (1) PT2516434E (OSRAM)
RS (1) RS54180B1 (OSRAM)
SG (1) SG181857A1 (OSRAM)
SI (1) SI2516434T1 (OSRAM)
SM (1) SMT201500199B (OSRAM)
TN (1) TN2012000316A1 (OSRAM)
TW (1) TWI457339B (OSRAM)
UA (1) UA107100C2 (OSRAM)
UY (1) UY33151A (OSRAM)
WO (1) WO2011079051A1 (OSRAM)
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Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8440689B2 (en) * 2009-12-23 2013-05-14 Takeda Pharmaceutical Company Limited Fused heteroaromatic pyrrolidinones
CA2828824A1 (en) * 2011-03-28 2012-10-04 F. Hoffmann-La Roche Ag Thiazolopyrimidine compounds
EP2723739B1 (en) 2011-06-22 2016-08-24 Takeda Pharmaceutical Company Limited Substituted 6-aza-isoindolin-1-one derivatives
WO2014051653A1 (en) 2012-09-27 2014-04-03 Portola Pharmaceuticals, Inc. Bicyclic dihydropyridone kinase inhibitors
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