HK1213181A1 - 雙環氧雜內酰胺激酶抑制劑 - Google Patents

雙環氧雜內酰胺激酶抑制劑

Info

Publication number
HK1213181A1
HK1213181A1 HK16101135.6A HK16101135A HK1213181A1 HK 1213181 A1 HK1213181 A1 HK 1213181A1 HK 16101135 A HK16101135 A HK 16101135A HK 1213181 A1 HK1213181 A1 HK 1213181A1
Authority
HK
Hong Kong
Prior art keywords
kinase inhibitors
oxa
bicyclic
lactam kinase
lactam
Prior art date
Application number
HK16101135.6A
Other languages
English (en)
Inventor
Anjali Pandey
Yonghong Song
Qing Xu
Original Assignee
Portola Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Portola Pharm Inc filed Critical Portola Pharm Inc
Publication of HK1213181A1 publication Critical patent/HK1213181A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK16101135.6A 2012-09-27 2016-02-01 雙環氧雜內酰胺激酶抑制劑 HK1213181A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261706712P 2012-09-27 2012-09-27
PCT/US2013/000225 WO2014051654A2 (en) 2012-09-27 2013-09-27 Bicyclic oxa-lactam kinase inhibitors

Publications (1)

Publication Number Publication Date
HK1213181A1 true HK1213181A1 (zh) 2016-06-30

Family

ID=50389107

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16101135.6A HK1213181A1 (zh) 2012-09-27 2016-02-01 雙環氧雜內酰胺激酶抑制劑

Country Status (4)

Country Link
US (1) US9469654B2 (zh)
EP (1) EP2900243A4 (zh)
HK (1) HK1213181A1 (zh)
WO (1) WO2014051654A2 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2900243A4 (en) 2012-09-27 2016-04-13 Portola Pharm Inc BICYCLIC OXA LACTAM KINASE HEMMER
EA202192575A1 (ru) 2019-03-21 2022-01-14 Онксео Соединения dbait в сочетании с ингибиторами киназ для лечения рака
US20220401436A1 (en) 2019-11-08 2022-12-22 INSERM (Institute National de la Santé et de la Recherche Médicale) Methods for the treatment of cancers that have acquired resistance to kinase inhibitors
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6130214A (en) 1997-10-27 2000-10-10 Dr. Reddy's Research Foundation Benzothiazin and benzoxazin derivatives; their preparation and uses
AU2005292314B2 (en) * 2004-09-29 2011-11-03 Portola Pharmaceuticals, Inc. Substituted 2H-1,3-benzoxazin-4(3H)-ones
ES2744541T3 (es) 2008-12-08 2020-02-25 Gilead Connecticut Inc Inhibidores de imidazopirazina Syk
EP2376481B1 (en) * 2009-01-13 2013-08-07 Glaxo Group Limited Pyrimidinecarboxamide derivatives as inhibitors of syk kinase
US8981087B2 (en) * 2009-07-29 2015-03-17 Karus Therapeutics Limited Benzo [E] [1,3] oxazin-4-one derivatives as phosphoinositide 3-kinase inhibitors
PL2516434T3 (pl) * 2009-12-23 2015-11-30 Takeda Pharmaceuticals Co Skondensowane heteroaromatyczne pirolidynony jako inhibitory SYK
CA2816219C (en) * 2010-11-01 2019-10-29 Portola Pharmaceuticals, Inc. Nicotinamides as syk modulators
EP2900243A4 (en) 2012-09-27 2016-04-13 Portola Pharm Inc BICYCLIC OXA LACTAM KINASE HEMMER

Also Published As

Publication number Publication date
WO2014051654A2 (en) 2014-04-03
EP2900243A2 (en) 2015-08-05
WO2014051654A3 (en) 2014-05-22
US20150252056A1 (en) 2015-09-10
EP2900243A4 (en) 2016-04-13
US9469654B2 (en) 2016-10-18

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