IT1116493B - Procedimento per la produzione di interferon e composizioni che lo contengono - Google Patents

Procedimento per la produzione di interferon e composizioni che lo contengono

Info

Publication number
IT1116493B
IT1116493B IT47712/79A IT4771279A IT1116493B IT 1116493 B IT1116493 B IT 1116493B IT 47712/79 A IT47712/79 A IT 47712/79A IT 4771279 A IT4771279 A IT 4771279A IT 1116493 B IT1116493 B IT 1116493B
Authority
IT
Italy
Prior art keywords
production process
compositions containing
interferon production
interferon
compositions
Prior art date
Application number
IT47712/79A
Other languages
English (en)
Other versions
IT7947712A0 (it
Original Assignee
Hayashibara Ken
Ashida Shin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP536878A external-priority patent/JPS5498307A/ja
Priority claimed from JP13402678A external-priority patent/JPS5562024A/ja
Application filed by Hayashibara Ken, Ashida Shin filed Critical Hayashibara Ken
Publication of IT7947712A0 publication Critical patent/IT7947712A0/it
Application granted granted Critical
Publication of IT1116493B publication Critical patent/IT1116493B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/91—Cell lines ; Processes using cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/811—Interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT47712/79A 1978-01-22 1979-01-19 Procedimento per la produzione di interferon e composizioni che lo contengono IT1116493B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP536878A JPS5498307A (en) 1978-01-22 1978-01-22 Production of interferon
JP13402678A JPS5562024A (en) 1978-10-31 1978-10-31 Preventive and remedy for interferon-sensitive disease

Publications (2)

Publication Number Publication Date
IT7947712A0 IT7947712A0 (it) 1979-01-19
IT1116493B true IT1116493B (it) 1986-02-10

Family

ID=26339293

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47712/79A IT1116493B (it) 1978-01-22 1979-01-19 Procedimento per la produzione di interferon e composizioni che lo contengono

Country Status (14)

Country Link
US (1) US4276282A (it)
AU (1) AU533201B2 (it)
CA (1) CA1135186A (it)
CH (1) CH637831A5 (it)
DE (1) DE2902136C2 (it)
DK (1) DK153848C (it)
ES (1) ES477060A1 (it)
FI (1) FI66428C (it)
FR (1) FR2414920A1 (it)
GB (1) GB2016015B (it)
IT (1) IT1116493B (it)
NL (1) NL192086C (it)
NO (1) NO152976C (it)
SE (1) SE436969B (it)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5598118A (en) * 1979-01-18 1980-07-25 Hayashibara Takeshi Preparation of type-2 interferon and drug containing the same
JPS55122717A (en) * 1979-03-15 1980-09-20 Asai Gerumaniumu Kenkyusho:Kk Interferon inducer
WO1981001102A1 (en) * 1979-10-19 1981-04-30 A Romano Medicine for the treatment of viral infections of the eye and other organs
US4328207A (en) * 1979-12-27 1982-05-04 Ken Hayashibara Process for preparing mouse interferon
US4497796A (en) * 1980-03-26 1985-02-05 The Regents Of The University Of California Gene transfer in intact mammals
US4396601A (en) * 1980-03-26 1983-08-02 The Regents Of The University Of Calif. Gene transfer in intact mammals
JPS6045848B2 (ja) * 1980-07-31 1985-10-12 株式会社林原生物化学研究所 ヒト成長ホルモンの製造方法
JPS5729294A (en) * 1980-07-30 1982-02-17 Hayashibara Biochem Lab Inc Preparation of human insulin
US4621053A (en) * 1980-07-30 1986-11-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for the production of human peptide hormones
JPS5826317B2 (ja) * 1980-12-30 1983-06-02 株式会社 林原生物化学研究所 ヒト甲状腺刺激ホルモンの製造方法
JPS6045850B2 (ja) * 1980-12-13 1985-10-12 株式会社林原生物化学研究所 ヒト副腎皮質刺激ホルモンの製法
JPS6045851B2 (ja) * 1980-12-19 1985-10-12 株式会社林原生物化学研究所 ヒト胎盤性ラクトゲンの製造方法
JPS5825439B2 (ja) * 1980-12-30 1983-05-27 株式会社林原生物化学研究所 ヒト副甲状腺ホルモンの製造方法
JPS5825440B2 (ja) * 1980-12-30 1983-05-27 株式会社林原生物化学研究所 ヒトカルシトニンの製造方法
JPS5739795A (en) * 1980-08-22 1982-03-05 Hayashibara Biochem Lab Inc Preparation of human prolactin
US4462985A (en) * 1980-08-22 1984-07-31 University Of Illinois Foundation Delivery of biologically active components of heterologous species interferon isolates
JPS586475B2 (ja) * 1980-08-23 1983-02-04 株式会社 林原生物化学研究所 ヒト絨毛性性腺刺激ホルモンの製造方法
JPS6045849B2 (ja) * 1980-08-25 1985-10-12 林原 健 ヒトエリトロポエチンの製造方法
JPS585671B2 (ja) * 1980-08-27 1983-02-01 株式会社 林原生物化学研究所 ヒト卵胞刺激ホルモンの製造方法
JPS5743696A (en) * 1980-08-27 1982-03-11 Hayashibara Biochem Lab Inc Preparation of human luteinizing hormone
JPS5852634B2 (ja) * 1980-12-05 1983-11-24 株式会社林原生物化学研究所 ウロキナ−ゼの製造法
JPS609795B2 (ja) * 1980-12-11 1985-03-13 株式会社林原生物化学研究所 ヒト上皮細胞成長因子の製造方法
US4364863A (en) * 1980-12-29 1982-12-21 Schering Corporation Extraction of interferon from bacteria
JPS6030657B2 (ja) * 1980-12-31 1985-07-17 株式会社林原生物化学研究所 ヒト細胞増殖促進因子の製造方法
JPS6030654B2 (ja) * 1980-12-31 1985-07-17 株式会社林原生物化学研究所 ヒトコロニ−刺激因子の製造方法
SE8204382L (sv) * 1981-07-21 1983-01-22 Hayashibara Biochem Lab Sett att framstella malcellysfaktor och anvendning derav
DE3249946C2 (de) * 1981-07-21 1996-03-21 Hayashibara Biochem Lab hTNF-haltiges therapeutisches Mittel gegen maligne Tumoren und dessen Verwendung
EP0090837A1 (en) * 1981-10-08 1983-10-12 BERG, Kurt Frimann Method and composition for treating a patient suffering from interferonsusceptible disorder
US4675295A (en) * 1981-10-28 1987-06-23 Denki Kagaku Kogyo Kabushiki Kaisha Process for producing subculturable lymphokine-producing human T cell hybridomas
JPS58126786A (ja) * 1982-01-25 1983-07-28 Hayashibara Biochem Lab Inc ヒトカリクレインの製造方法
JPS58138395A (ja) * 1982-02-12 1983-08-17 Hayashibara Biochem Lab Inc ヒト免疫応答抑制因子の製造方法
US4624917A (en) * 1982-02-17 1986-11-25 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for the production of human T-cell growth factor
US4987079A (en) * 1982-07-06 1991-01-22 Wilbur D. Smith Composition and method for in vitro cell culture
AU2038283A (en) * 1982-08-10 1984-03-07 Trustees Of Columbia University In The City Of New York, The The use of eucaryotic promoter sequences in the production ofproteinaceous materials
US5702699A (en) * 1982-09-23 1997-12-30 Cetus Corporation Process for the recovery of lipophilic proteins
US4870009A (en) * 1982-11-22 1989-09-26 The Salk Institute For Biological Studies Method of obtaining gene product through the generation of transgenic animals
US4820515A (en) * 1982-12-13 1989-04-11 Texas A&M University System Method of using interferon in low dosage to regulate appetite and efficiency of food utilization
US5910304A (en) * 1982-12-13 1999-06-08 Texas A&M University System Low-dose oral administration of interferons
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
US4489163A (en) 1983-04-14 1984-12-18 The Salk Institute For Biological Studies rCRF and analogs
WO1984004887A1 (en) * 1983-06-13 1984-12-20 Ragnvald Erik Lindblom A METHOD OF TREATING INTERFERON SENSITIVE DISEASES, AND A METHOD AND A DEVICE FOR PREPARING A gamma-INTERFERON CONTAINING PREPARATION
US4680174A (en) * 1984-05-24 1987-07-14 Damon Biotech, Inc. Induction of immune response by immunization with encapsulated antigen-producing cells
US5019385A (en) * 1984-11-09 1991-05-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Novel lymphopine LK 2 and pharmaceutic compositions containing same
CA1320905C (en) 1986-11-06 1993-08-03 Joseph M. Cummins Treatment of immuno-resistant disease
ZA878295B (en) * 1986-11-06 1988-05-03 Amarillo Cell Culture Co. Inc. Treatment of immuno-resistant disease
US5175385A (en) * 1987-09-03 1992-12-29 Ohio University/Edison Animal Biotechnolgy Center Virus-resistant transgenic mice
DE3731255A1 (de) * 1987-09-17 1989-04-06 Boehringer Ingelheim Int Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen
US5017371A (en) * 1988-01-06 1991-05-21 Amarillo Cell Culture Company, Incorporated Method for reducing side effects of cancer therapy
JPH0665297A (ja) * 1992-08-21 1994-03-08 Hayashibara Biochem Lab Inc メラニン合成抑制蛋白質とその製造方法並びに用途
EP0619120B1 (en) * 1993-04-09 2002-09-11 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Use of human interferon-alpha for the manufacture of a medicament for treatment of respiratory disease in cats
US7135458B1 (en) 1995-11-15 2006-11-14 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interferon-γ inducing polypeptide, pharmaceutical composition thereof, monoclonal antibody thereto, and methods of use
JP4004088B2 (ja) 1995-09-26 2007-11-07 株式会社林原生物化学研究所 免疫担当細胞においてインターフェロン−γの産生を誘導する蛋白質
US5723718A (en) * 1994-12-20 1998-03-03 St. Joseph's Hospital And Medical Center Induction of immune tolerance to tumor cells
US5939286A (en) * 1995-05-10 1999-08-17 University Of Florida Hybrid interferon tau/alpha polypeptides, their recombinant production, and methods using them
US6204022B1 (en) 1996-04-12 2001-03-20 Pepgen Corporation And University Of Florida Low-toxicity human interferon-alpha analogs
JPH1080270A (ja) * 1996-07-19 1998-03-31 Hayashibara Biochem Lab Inc ポリペプチドをプロセッシングする酵素
TW515843B (en) * 1996-07-25 2003-01-01 Hayashibara Biochem Lab Process for producing an active polypeptide inducing interferon-γ production
US6514728B1 (en) * 1998-11-09 2003-02-04 Nippon Biocaptal Limited Process for preparation of cytokines using Sendai virus expression system
EP1092773A3 (en) * 1999-10-15 2001-08-08 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Polypeptide and uses thereof
JP2002201141A (ja) * 2000-10-27 2002-07-16 Hayashibara Biochem Lab Inc 蛋白質合成抑制遺伝子の発現増強剤
CN1568369A (zh) * 2001-08-12 2005-01-19 派普根公司 杂合的干扰素/干扰素Tau蛋白、组合物和使用方法
EP2978438A1 (en) 2013-03-29 2016-02-03 Centre National de la Recherche Scientifique (C.N.R.S.) Cgrp receptor agonist for hiv treatment or prevention
WO2015140348A2 (en) 2014-03-21 2015-09-24 Centre National De La Recherche Scientifique (Cnrs) Use of dj-1 deglycase activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6914761D0 (pt) * 1969-01-17 1973-03-08 Merck & Co Inc Processos quimicos

Also Published As

Publication number Publication date
DK153848B (da) 1988-09-12
SE436969B (sv) 1985-02-04
FI66428B (fi) 1984-06-29
CH637831A5 (fr) 1983-08-31
FI790188A (fi) 1979-07-23
DK153848C (da) 1989-04-03
NO152976C (no) 1985-12-27
US4276282A (en) 1981-06-30
CA1135186A (en) 1982-11-09
AU4334579A (en) 1979-08-02
AU533201B2 (en) 1983-11-10
FR2414920B1 (it) 1982-08-06
FR2414920A1 (fr) 1979-08-17
SE7900493L (sv) 1979-07-23
NL192086B (nl) 1996-10-01
FI66428C (fi) 1984-10-10
DK25579A (da) 1979-07-23
NO790195L (no) 1979-07-24
NO152976B (no) 1985-09-16
GB2016015B (en) 1982-05-06
ES477060A1 (es) 1979-12-16
NL7900476A (nl) 1979-07-24
GB2016015A (en) 1979-09-19
DE2902136C2 (de) 1986-09-04
DE2902136A1 (de) 1979-08-09
IT7947712A0 (it) 1979-01-19
NL192086C (nl) 1997-02-04

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960126