|
US5776093A
(en)
*
|
1985-07-05 |
1998-07-07 |
Immunomedics, Inc. |
Method for imaging and treating organs and tissues
|
|
US7744877B2
(en)
*
|
1992-11-13 |
2010-06-29 |
Biogen Idec Inc. |
Expression and use of anti-CD20 Antibodies
|
|
US5736137A
(en)
*
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
|
RU2139731C1
(ru)
*
|
1992-11-13 |
1999-10-20 |
Айдек Фармасьютикалс Корпорейшн (US |
Способ лечения, антитела, гибридома
|
|
US6306393B1
(en)
*
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
EP1215497B1
(en)
*
|
1997-12-16 |
2009-01-07 |
University Of Zurich |
Diagnostics for transmissible spongiform encephalopathy
|
|
PT2180007E
(pt)
|
1998-04-20 |
2013-11-25 |
Roche Glycart Ag |
Engenharia de glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos
|
|
US6962702B2
(en)
*
|
1998-06-22 |
2005-11-08 |
Immunomedics Inc. |
Production and use of novel peptide-based agents for use with bi-specific antibodies
|
|
MY136203A
(en)
*
|
1998-08-11 |
2008-08-29 |
Idec Pharma Corp |
Combination therapies for b-cell lymphomas comprising administration of anti-cd20 antibody
|
|
US20010033839A1
(en)
*
|
1999-10-04 |
2001-10-25 |
Emilio Barbera-Guillem |
Vaccine and immunotherapy for solid nonlymphoid tumor and related immune dysregulation
|
|
WO2000027428A1
(en)
*
|
1998-11-09 |
2000-05-18 |
Idec Pharmaceuticals Corporation |
Treatment of hematologic malignancies associated with circulating tumor cells using chimeric anti-cd20 antibody
|
|
MY155913A
(en)
*
|
1998-11-09 |
2015-12-15 |
Biogen Inc |
Chimeric anti-cd20 antibody treatment of patients receiving bmt or pbsc transpants
|
|
CA2363568A1
(en)
*
|
1999-03-04 |
2000-09-08 |
Kyowa Hakko Kogyo Co., Ltd. |
Diagnostic agent and therapeutic agent for leukemia
|
|
US7696325B2
(en)
*
|
1999-03-10 |
2010-04-13 |
Chugai Seiyaku Kabushiki Kaisha |
Polypeptide inducing apoptosis
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
JP4636696B2
(ja)
*
|
1999-04-20 |
2011-02-23 |
アーオー テクノロジー アクチエンゲゼルシャフト |
ヒト又は動物の器官の表面における3d座標の経皮的獲得用の装置
|
|
BR0011197A
(pt)
*
|
1999-05-07 |
2002-02-19 |
Genentech Inc |
Método de tratamento de uma doença autoimunológica em um mamìfero, compreendendo antagonistas que se ligam aos marcadores de superfìcie de células b e artigo de manufatura
|
|
US7829064B2
(en)
*
|
1999-05-10 |
2010-11-09 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods
|
|
US8119101B2
(en)
|
1999-05-10 |
2012-02-21 |
The Ohio State University |
Anti-CD74 immunoconjugates and methods of use
|
|
US8383081B2
(en)
*
|
1999-05-10 |
2013-02-26 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods of use
|
|
US8557244B1
(en)
*
|
1999-08-11 |
2013-10-15 |
Biogen Idec Inc. |
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
|
|
US6451284B1
(en)
*
|
1999-08-11 |
2002-09-17 |
Idec Pharmaceuticals Corporation |
Clinical parameters for determining hematologic toxicity prior to radioimmunotheraphy
|
|
US20030143234A1
(en)
*
|
1999-08-20 |
2003-07-31 |
Wenyuan Shi |
Anti-microbial targeting chimeric pharmaceutical
|
|
US7569542B2
(en)
|
1999-08-20 |
2009-08-04 |
The Regents Of The University Of California |
Anti-microbial targeting chimeric pharmaceutical
|
|
US20020028178A1
(en)
*
|
2000-07-12 |
2002-03-07 |
Nabil Hanna |
Treatment of B cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
|
|
US20020006404A1
(en)
*
|
1999-11-08 |
2002-01-17 |
Idec Pharmaceuticals Corporation |
Treatment of cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
|
|
AU8729101A
(en)
*
|
2000-03-31 |
2001-10-15 |
Idec Pharma Corp |
Combined use of anti-cytokine antibodies or antagonists and anti-CD20 for the treatment of B cell lymphoma
|
|
JP2004512262A
(ja)
|
2000-06-20 |
2004-04-22 |
アイデック ファーマスーティカルズ コーポレイション |
非放射性抗cd20抗体/放射標識抗cd22抗体の組合せ
|
|
WO2001097843A2
(en)
*
|
2000-06-22 |
2001-12-27 |
University Of Iowa Research Foundation |
Methods for enhancing antibody-induced cell lysis and treating cancer
|
|
CN1592645A
(zh)
*
|
2000-09-18 |
2005-03-09 |
拜奥根Idec公司 |
使用b细胞耗尽/免疫调节抗体组合治疗自身免疫病的联合疗法
|
|
AU2002213357A1
(en)
*
|
2000-10-20 |
2002-05-06 |
Idec Pharmaceuticals Corporation |
Variant igg3 rituxan r and therapeutic use thereof
|
|
US20040242847A1
(en)
*
|
2000-10-20 |
2004-12-02 |
Naoshi Fukushima |
Degraded agonist antibody
|
|
DE60133479T2
(de)
*
|
2000-10-20 |
2009-04-16 |
Chugai Seiyaku K.K. |
Modifizierter tpo-agonisten antikörper
|
|
EP1373321A2
(en)
*
|
2001-01-29 |
2004-01-02 |
Idec Pharmaceuticals Corporation |
Modified antibodies and methods of use
|
|
US20030211107A1
(en)
*
|
2002-01-31 |
2003-11-13 |
Kandasamy Hariharan |
Use of CD23 antagonists for the treatment of neoplastic disorders
|
|
US20070065436A1
(en)
*
|
2001-01-31 |
2007-03-22 |
Biogen Idec Inc. |
Anti-cd80 antibody having adcc activity for adcc mediated killing of b cell lymphoma cells alone or in combination with other therapies
|
|
US20020159996A1
(en)
|
2001-01-31 |
2002-10-31 |
Kandasamy Hariharan |
Use of CD23 antagonists for the treatment of neoplastic disorders
|
|
US20030103971A1
(en)
*
|
2001-11-09 |
2003-06-05 |
Kandasamy Hariharan |
Immunoregulatory antibodies and uses thereof
|
|
JP2004527528A
(ja)
*
|
2001-04-09 |
2004-09-09 |
プロジェニクス・ファーマスーティカルズ・インコーポレイテッド |
抗cd19免疫毒素
|
|
EP1387697A4
(en)
*
|
2001-05-17 |
2005-04-20 |
Jolla Pharma |
METHOD FOR TREATING ANTIBODY-MEDIATED DISEASES USING MEANS TO INHIBIT CD21
|
|
US20020193569A1
(en)
*
|
2001-06-04 |
2002-12-19 |
Idec Pharmaceuticals Corporation |
Bispecific fusion protein and method of use for enhancing effector cell killing of target cells
|
|
EP1404366A4
(en)
*
|
2001-06-14 |
2006-06-07 |
Intermune Inc |
COMBINED THERAPY USING INTERFERON GAMMA AND SPECIFIC B-CELL ANTIBODIES
|
|
CA2455365C
(en)
|
2001-08-03 |
2014-07-29 |
Glycart Biotechnology Ag |
Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
|
|
MXPA04006327A
(es)
*
|
2001-12-26 |
2005-07-13 |
Ibc Pharmaceuticals |
Metodos para generar agentes multivalentes, multiespecificos de dominios vh y vl.
|
|
US8287864B2
(en)
*
|
2002-02-14 |
2012-10-16 |
Immunomedics, Inc. |
Structural variants of antibodies for improved therapeutic characteristics
|
|
CN100522999C
(zh)
|
2002-02-14 |
2009-08-05 |
免疫医疗公司 |
抗cd20抗体及其融合蛋白和使用方法
|
|
AU2003215365A1
(en)
|
2002-02-21 |
2003-09-09 |
Duke University |
Treatment methods using anti-cd22 antibodies
|
|
US8435529B2
(en)
|
2002-06-14 |
2013-05-07 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
|
US8877901B2
(en)
|
2002-12-13 |
2014-11-04 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US7591994B2
(en)
|
2002-12-13 |
2009-09-22 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US9770517B2
(en)
|
2002-03-01 |
2017-09-26 |
Immunomedics, Inc. |
Anti-Trop-2 antibody-drug conjugates and uses thereof
|
|
PT3483183T
(pt)
|
2002-03-01 |
2021-06-02 |
Immunomedics Inc |
Imunoconjugado compreendendo anticorpos rs7 humanizados
|
|
US9745380B2
(en)
|
2002-03-01 |
2017-08-29 |
Immunomedics, Inc. |
RS7 antibodies
|
|
US20030180292A1
(en)
*
|
2002-03-14 |
2003-09-25 |
Idec Pharmaceuticals |
Treatment of B cell malignancies using anti-CD40L antibodies in combination with anti-CD20 antibodies and/or chemotherapeutics and radiotherapy
|
|
GB0210121D0
(en)
*
|
2002-05-02 |
2002-06-12 |
Celltech R&D Ltd |
Biological products
|
|
SG165158A1
(en)
*
|
2002-05-02 |
2010-10-28 |
Wyeth Corp |
Calicheamicin derivative-carrier conjugates
|
|
AU2012244218C1
(en)
*
|
2002-05-02 |
2016-12-15 |
Wyeth Holdings Llc. |
Calicheamicin derivative-carrier conjugates
|
|
EP1507562B1
(en)
*
|
2002-05-29 |
2010-03-24 |
Immunomedics, Inc. |
Compositions for radioimmunotherapy of brain
|
|
ATE414105T1
(de)
*
|
2002-10-11 |
2008-11-15 |
Chugai Pharmaceutical Co Ltd |
Zelltod-induzierender wirkstoff
|
|
CN101928344B
(zh)
*
|
2002-10-17 |
2014-08-13 |
根马布股份公司 |
抗cd20的人单克隆抗体
|
|
US8034831B2
(en)
*
|
2002-11-06 |
2011-10-11 |
Celgene Corporation |
Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies
|
|
US7563810B2
(en)
*
|
2002-11-06 |
2009-07-21 |
Celgene Corporation |
Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
|
|
US8420086B2
(en)
|
2002-12-13 |
2013-04-16 |
Immunomedics, Inc. |
Camptothecin conjugates of anti-CD22 antibodies for treatment of B cell diseases
|
|
US7534427B2
(en)
*
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
|
JP4874090B2
(ja)
*
|
2003-01-31 |
2012-02-08 |
イミューノメディクス、インコーポレイテッド |
治療薬および診断薬を投与するための方法および組成物
|
|
CA2516971A1
(en)
|
2003-02-24 |
2004-09-02 |
Institut Pasteur |
Secreted chlamydia polypeptides, polynucleotides coding therefor, therapeutic and diagnostic uses thereof
|
|
JP2004279086A
(ja)
*
|
2003-03-13 |
2004-10-07 |
Konica Minolta Holdings Inc |
放射線画像変換パネル及び放射線画像変換パネルの製造方法
|
|
EP1609803A4
(en)
*
|
2003-03-31 |
2006-05-24 |
Chugai Pharmaceutical Co Ltd |
MODIFIED ANTIBODY AGAINST CD22 AND ITS USE
|
|
WO2004111233A1
(ja)
*
|
2003-06-11 |
2004-12-23 |
Chugai Seiyaku Kabushiki Kaisha |
抗体の製造方法
|
|
US7109304B2
(en)
|
2003-07-31 |
2006-09-19 |
Immunomedics, Inc. |
Humanized anti-CD19 antibodies
|
|
US7902338B2
(en)
|
2003-07-31 |
2011-03-08 |
Immunomedics, Inc. |
Anti-CD19 antibodies
|
|
CA2534898A1
(en)
*
|
2003-08-08 |
2005-02-17 |
Immunomedics, Inc. |
Bispecific antibodies for inducing apoptosis of tumor and diseased cells
|
|
ES2456325T3
(es)
*
|
2003-11-06 |
2014-04-22 |
Seattle Genetics, Inc. |
Compuestos de monometilvalina capaces de conjugación con ligandos
|
|
TW200530269A
(en)
*
|
2003-12-12 |
2005-09-16 |
Chugai Pharmaceutical Co Ltd |
Anti-Mpl antibodies
|
|
JPWO2005056602A1
(ja)
*
|
2003-12-12 |
2008-03-06 |
中外製薬株式会社 |
アゴニスト活性を有する改変抗体のスクリーニング方法
|
|
US8883160B2
(en)
*
|
2004-02-13 |
2014-11-11 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
|
US9550838B2
(en)
|
2004-02-13 |
2017-01-24 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
|
US7875598B2
(en)
*
|
2004-03-04 |
2011-01-25 |
The Regents Of The University Of California |
Compositions useful for the treatment of microbial infections
|
|
EP1757686A4
(en)
*
|
2004-04-09 |
2008-03-12 |
Chugai Pharmaceutical Co Ltd |
INDUCER OF CELL DEATH
|
|
US8470315B2
(en)
*
|
2004-04-13 |
2013-06-25 |
Quintessence Biosciences, Inc. |
Non-natural ribonuclease conjugates as cytotoxic agents
|
|
WO2005103081A2
(en)
*
|
2004-04-20 |
2005-11-03 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
|
EA012464B1
(ru)
|
2004-08-04 |
2009-10-30 |
Эпплайд Молекьюлар Эволюшн, Инк. |
Антитело против cd20 и его применение
|
|
US9707302B2
(en)
|
2013-07-23 |
2017-07-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
US10058621B2
(en)
|
2015-06-25 |
2018-08-28 |
Immunomedics, Inc. |
Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers
|
|
EP1870458B1
(en)
|
2005-03-31 |
2018-05-09 |
Chugai Seiyaku Kabushiki Kaisha |
sc(Fv)2 STRUCTURAL ISOMERS
|
|
EP3050963B1
(en)
|
2005-03-31 |
2019-09-18 |
Chugai Seiyaku Kabushiki Kaisha |
Process for production of polypeptide by regulation of assembly
|
|
US8349332B2
(en)
|
2005-04-06 |
2013-01-08 |
Ibc Pharmaceuticals, Inc. |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases
|
|
US8475794B2
(en)
|
2005-04-06 |
2013-07-02 |
Ibc Pharmaceuticals, Inc. |
Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases
|
|
ES2417065T3
(es)
|
2005-04-26 |
2013-08-05 |
Trion Pharma Gmbh |
Combinación de anticuerpos con glucocorticoides para el tratamiento del cáncer
|
|
WO2006119365A2
(en)
|
2005-05-02 |
2006-11-09 |
Cold Spring Harbor Laboratory |
Composition and methods for cancer diagnosis utilizing the mir 17-92 cluster
|
|
WO2006123724A1
(ja)
*
|
2005-05-18 |
2006-11-23 |
The University Of Tokushima |
抗hla抗体を利用した新規医薬品
|
|
JP5068167B2
(ja)
*
|
2005-06-10 |
2012-11-07 |
中外製薬株式会社 |
メグルミンを含有するタンパク質製剤の安定化剤、およびその利用
|
|
CN101262885B
(zh)
|
2005-06-10 |
2015-04-01 |
中外制药株式会社 |
含有sc(Fv)2的药物组合物
|
|
EP3348639A3
(en)
*
|
2005-06-10 |
2018-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Sc(fv)2 site-directed mutant
|
|
US20070110757A1
(en)
|
2005-06-23 |
2007-05-17 |
Ziping Wei |
Antibody formulations having optimized aggregation and fragmentation profiles
|
|
US20070190047A1
(en)
*
|
2005-07-29 |
2007-08-16 |
Amgen, Inc. |
Formulations that inhibit protein aggregation
|
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
|
EP2639242A3
(en)
*
|
2006-03-06 |
2013-10-16 |
MedImmune, Inc. |
Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
US8389688B2
(en)
|
2006-03-06 |
2013-03-05 |
Aeres Biomedical, Ltd. |
Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
ES2654040T3
(es)
*
|
2006-03-31 |
2018-02-12 |
Chugai Seiyaku Kabushiki Kaisha |
Método de modificación de anticuerpos para la purificación de anticuerpos biespecíficos
|
|
US8592149B2
(en)
|
2006-04-27 |
2013-11-26 |
Pikamab, Inc. |
Methods and compositions for antibody therapy
|
|
WO2007145227A1
(ja)
*
|
2006-06-14 |
2007-12-21 |
Chugai Seiyaku Kabushiki Kaisha |
造血幹細胞増加促進剤
|
|
US8840882B2
(en)
*
|
2006-06-23 |
2014-09-23 |
Quintessence Biosciences, Inc. |
Modified ribonucleases
|
|
CN101517075A
(zh)
*
|
2006-07-13 |
2009-08-26 |
中外制药株式会社 |
细胞死亡诱导剂
|
|
US8298801B2
(en)
|
2006-07-17 |
2012-10-30 |
Quintessence Biosciences, Inc. |
Methods and compositions for the treatment of cancer
|
|
CA2957056A1
(en)
|
2006-09-06 |
2008-03-13 |
C3 Jian, Inc. |
Selectively targeted antimicrobial peptides and the use thereof
|
|
WO2008034076A2
(en)
*
|
2006-09-15 |
2008-03-20 |
The Johns Hopkins University |
Cyclophosphamide in combination with immune therapeutics
|
|
WO2008034074A2
(en)
|
2006-09-15 |
2008-03-20 |
The Johns Hopkins University |
Cyclosphosphamide in combination with anti-idiotypic vaccines
|
|
WO2008034071A2
(en)
|
2006-09-15 |
2008-03-20 |
The Johns Hopkins University |
Method of identifying patients suitable for high-dose cyclophosphamide treatment
|
|
CA2671457C
(en)
|
2006-12-01 |
2017-09-26 |
Medarex, Inc. |
Human antibodies that bind cd22 and uses thereof
|
|
RU2475265C2
(ru)
|
2007-01-16 |
2013-02-20 |
Эбботт Лэборетриз |
Способы лечения псориаза
|
|
CL2008000719A1
(es)
*
|
2007-03-12 |
2008-09-05 |
Univ Tokushima Chugai Seiyaku |
Agente terapeutico para cancer resistente a agentes quimioterapeuticos que comprende un anticuerpo que reconoce hla de clase i como ingrediente activo; composicion farmaceutica que comprende dicho anticuerpo; y metodo para tratar cancer resistente a
|
|
MX2009010361A
(es)
|
2007-03-29 |
2009-10-16 |
Abbott Lab |
Anticuerpos il-12 anti-humanos cristalinos.
|
|
CL2008002083A1
(es)
|
2007-07-16 |
2008-11-21 |
Genentech Inc |
Anticuerpo humanizado anti-cd79b/igbeta/b29; inmunoconjugado; metodo in vitro para determinar presencia de cd79b, inhibir crecimiento de celula con cd79b, o para detectara celula b; metodo para elaborar dicho anticyerpo humanizado; acido nucleico; celula huesped; composicion; metodo de elaboracion de inmunoconjugado; uso medico
|
|
SI2474557T1
(sl)
|
2007-07-16 |
2014-12-31 |
Genentech, Inc. |
Protiteles proti CD79b in imunokonjugati in postopki za uporabo
|
|
WO2009048909A1
(en)
*
|
2007-10-08 |
2009-04-16 |
Quintessence Biosciences, Inc. |
Compositions and methods for ribonuclease-based therapies
|
|
US9026372B2
(en)
|
2007-11-21 |
2015-05-05 |
Accentia Biopharmaceuticals, Inc. |
Methods for providing a system of care for a high-dose oxazaphosphorine drug regimen
|
|
RS54883B1
(sr)
|
2008-01-31 |
2016-10-31 |
Genentech Inc |
Anti-cd79b antitela i imunokonjugati i metode upotrebe
|
|
RU2497545C2
(ru)
|
2008-03-18 |
2013-11-10 |
Эбботт Лэборетриз |
Способ лечения псориаза (варианты)
|
|
UA108735C2
(uk)
*
|
2008-07-21 |
2015-06-10 |
|
Структурні варіанти антитіл для покращення терапевтичних характеристик
|
|
TW201438738A
(zh)
|
2008-09-16 |
2014-10-16 |
Genentech Inc |
治療進展型多發性硬化症之方法
|
|
WO2010039985A1
(en)
|
2008-10-01 |
2010-04-08 |
Quintessence Biosciences, Inc. |
Therapeutic Ribonucleases
|
|
WO2010075249A2
(en)
|
2008-12-22 |
2010-07-01 |
Genentech, Inc. |
A method for treating rheumatoid arthritis with b-cell antagonists
|
|
LT3912643T
(lt)
|
2009-02-13 |
2023-02-10 |
Immunomedics Inc. |
Imunokonjugatai su ląstelės viduje skaldoma jungtimi
|
|
WO2010096394A2
(en)
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
|
BR112012004777A2
(pt)
|
2009-09-03 |
2019-09-24 |
Genentech Inc |
métodos para tratar diagnósticar e monitorar artrite reumatoide
|
|
CN102482701B
(zh)
|
2009-09-16 |
2015-05-13 |
免疫医疗公司 |
I类抗-cea抗体及其使用
|
|
IN2012DN03354A
(enExample)
|
2009-12-02 |
2015-10-23 |
Immunomedics Inc |
|
|
WO2011085354A1
(en)
*
|
2010-01-11 |
2011-07-14 |
Center For Molecular Medicine And Immunology |
Enhanced cytotoxicity of anti-cd74 and anti-hla-dr antibodies with interferon-gamma
|
|
BR112012020102A2
(pt)
|
2010-02-10 |
2016-11-29 |
Immunogen Inc |
anticorpos cd20 e usos dos mesmos.
|
|
US9540438B2
(en)
|
2011-01-14 |
2017-01-10 |
Redwood Bioscience, Inc. |
Aldehyde-tagged immunoglobulin polypeptides and methods of use thereof
|
|
EP2680884B1
(en)
|
2011-02-28 |
2018-01-17 |
F. Hoffmann-La Roche AG |
Biological markers and methods for predicting response to b-cell antagonists
|
|
AU2012250924B2
(en)
|
2011-05-02 |
2017-05-25 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
|
US9757458B2
(en)
*
|
2011-12-05 |
2017-09-12 |
Immunomedics, Inc. |
Crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in hematopoietic cancer cells
|
|
US9192664B2
(en)
|
2011-12-05 |
2015-11-24 |
Immunomedics, Inc. |
Therapeutic use of anti-CD22 antibodies for inducing trogocytosis
|
|
GB201201062D0
(en)
|
2012-01-23 |
2012-03-07 |
Ge Healthcare Ltd |
Radiofluorination method
|
|
CN104582717B
(zh)
|
2012-07-19 |
2018-03-13 |
雷德伍德生物科技股份有限公司 |
对cd22有特异性的抗体及其使用方法
|
|
EP3586874A1
(en)
|
2012-08-14 |
2020-01-01 |
IBC Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
|
US9382329B2
(en)
|
2012-08-14 |
2016-07-05 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
|
US9492566B2
(en)
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
US20240139324A1
(en)
|
2012-12-13 |
2024-05-02 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and sn-38 for improved efficacy and decreased toxicity
|
|
US10413539B2
(en)
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
|
US10744129B2
(en)
|
2012-12-13 |
2020-08-18 |
Immunomedics, Inc. |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2
|
|
WO2017004144A1
(en)
|
2015-07-01 |
2017-01-05 |
Immunomedics, Inc. |
Antibody-sn-38 immunoconjugates with a cl2a linker
|
|
JP6366111B2
(ja)
|
2012-12-13 |
2018-08-01 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
有効性の改善および毒性の減少のための、抗体およびsn−38からなるイムノコンジュゲートの投薬
|
|
US10206918B2
(en)
|
2012-12-13 |
2019-02-19 |
Immunomedics, Inc. |
Efficacy of anti-HLA-DR antiboddy drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers
|
|
US9931417B2
(en)
|
2012-12-13 |
2018-04-03 |
Immunomedics, Inc. |
Antibody-SN-38 immunoconjugates with a CL2A linker
|
|
US10137196B2
(en)
|
2012-12-13 |
2018-11-27 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
|
US12310958B2
(en)
|
2012-12-13 |
2025-05-27 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2015012904A2
(en)
|
2012-12-13 |
2015-01-29 |
Immunomedics, Inc. |
Antibody-sn-38 immunoconjugates with a cl2a linker
|
|
GB201308053D0
(en)
|
2013-05-03 |
2013-06-12 |
Ge Healthcare Ltd |
Metal complexes and fluorination thereof
|
|
US11253606B2
(en)
|
2013-07-23 |
2022-02-22 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
KR102441231B1
(ko)
|
2013-09-27 |
2022-09-06 |
추가이 세이야쿠 가부시키가이샤 |
폴리펩티드 이종 다량체의 제조방법
|
|
EP3107577B1
(en)
|
2014-02-21 |
2024-03-20 |
IBC Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to trop-2 expressing cells
|
|
EP3110445A4
(en)
|
2014-02-25 |
2017-09-27 |
Immunomedics, Inc. |
Humanized rfb4 anti-cd22 antibody
|
|
US9580495B2
(en)
|
2014-06-24 |
2017-02-28 |
Immunomedics, Inc. |
Anti-histone therapy for vascular necrosis in severe glomerulonephritis
|
|
GB201412658D0
(en)
|
2014-07-16 |
2014-08-27 |
Ucb Biopharma Sprl |
Molecules
|
|
RS60349B8
(sr)
|
2014-09-23 |
2022-10-31 |
Hoffmann La Roche |
Postupak upotrebe anti-cd79b imunokonjugata
|
|
SI3204018T1
(sl)
|
2014-10-07 |
2021-11-30 |
Immunomedics, Inc. |
Neoadjuvantna uporaba konjugatov protitelo-zdravilo
|
|
US10662240B2
(en)
|
2014-12-19 |
2020-05-26 |
Mabtech Ab |
Composition, kit and method for inhibition of IL-21 mediated activation of human cells
|
|
EP3286224A4
(en)
|
2015-04-22 |
2018-11-14 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells
|
|
CN114796501A
(zh)
|
2015-06-25 |
2022-07-29 |
免疫医疗公司 |
抗体与治疗剂的组合治疗癌症的方法
|
|
US10195175B2
(en)
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
|
GB201601075D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibodies molecules
|
|
GB201601077D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibody molecule
|
|
GB201601073D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibodies
|
|
AU2016354009B2
(en)
|
2015-11-09 |
2021-05-20 |
R.P. Scherer Technologies, Llc |
Anti-CD22 antibody-maytansine conjugates and methods of use thereof
|
|
SG11201803989WA
(en)
|
2015-12-28 |
2018-06-28 |
Chugai Pharmaceutical Co Ltd |
Method for promoting efficiency of purification of fc region-containing polypeptide
|
|
CA3011372A1
(en)
|
2016-02-10 |
2017-08-17 |
Immunomedics, Inc. |
Combination of abcg2 inhibitors with sacituzumab govitecan (immu-132) overcomes resistance to sn-38 in trop-2 expressing cancers
|
|
CA3019398A1
(en)
|
2016-04-26 |
2017-11-02 |
R.P. Scherer Technologies, Llc |
Antibody conjugates and methods of making and using the same
|
|
CA3016917A1
(en)
|
2016-04-27 |
2017-11-02 |
Immunomedics, Inc. |
Efficacy of anti-trop-2-sn-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors
|
|
JP7252627B2
(ja)
|
2016-12-15 |
2023-04-05 |
デューク ユニバーシティ |
制御性b10細胞を枯渇させる抗体および方法並びに免疫チェックポイント阻害剤との併用における使用
|
|
JP2020512314A
(ja)
|
2017-03-27 |
2020-04-23 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
サシツズマブゴビテカンとRAD51阻害剤を用いたTrop−2発現トリプルネガティブ乳癌の治療
|
|
CN110352201A
(zh)
|
2017-04-03 |
2019-10-18 |
免疫医疗公司 |
用于癌症疗法的抗体药物缀合物的皮下施用
|
|
CN115667310A
(zh)
|
2020-06-01 |
2023-01-31 |
创新生物有限公司 |
Cd22特异性抗体及其用途
|
|
CN116390772A
(zh)
|
2020-07-07 |
2023-07-04 |
博泰康医药公司 |
新型美登素类似物作为adc有效载荷及其在癌症治疗中的用途
|
|
KR102393776B1
(ko)
|
2020-12-30 |
2022-05-04 |
(주)이노베이션바이오 |
Cd22에 특이적인 인간화 항체 및 이를 이용한 키메라 항원 수용체
|
|
EP4342497A1
(en)
|
2021-05-10 |
2024-03-27 |
Kawasaki Institute of Industrial Promotion |
Antibody having reduced binding affinity for antigen
|