ATE171461T1 - Immunstimulierende monoklonale antikörper - Google Patents

Immunstimulierende monoklonale antikörper

Info

Publication number
ATE171461T1
ATE171461T1 AT95910891T AT95910891T ATE171461T1 AT E171461 T1 ATE171461 T1 AT E171461T1 AT 95910891 T AT95910891 T AT 95910891T AT 95910891 T AT95910891 T AT 95910891T AT E171461 T1 ATE171461 T1 AT E171461T1
Authority
AT
Austria
Prior art keywords
immuno
monoclonal antibodies
stimulating monoclonal
stimulating
tumor
Prior art date
Application number
AT95910891T
Other languages
English (en)
Inventor
Britta Hardy
Avraham Novogrodsky
Original Assignee
Mor Research Applic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mor Research Applic Ltd filed Critical Mor Research Applic Ltd
Application granted granted Critical
Publication of ATE171461T1 publication Critical patent/ATE171461T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Detergent Compositions (AREA)
AT95910891T 1994-01-31 1995-01-30 Immunstimulierende monoklonale antikörper ATE171461T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL10850194A IL108501A (en) 1994-01-31 1994-01-31 Antibodies and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ATE171461T1 true ATE171461T1 (de) 1998-10-15

Family

ID=11065761

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95910891T ATE171461T1 (de) 1994-01-31 1995-01-30 Immunstimulierende monoklonale antikörper

Country Status (20)

Country Link
US (1) US5897862A (de)
EP (1) EP0742795B1 (de)
JP (1) JP3478398B2 (de)
CN (1) CN1052733C (de)
AT (1) ATE171461T1 (de)
AU (1) AU693526B2 (de)
CA (1) CA2182289C (de)
DE (1) DE69504955T2 (de)
DK (1) DK0742795T3 (de)
EE (1) EE03285B1 (de)
ES (1) ES2124533T3 (de)
FI (1) FI963004A (de)
IL (1) IL108501A (de)
LT (1) LT4225B (de)
LV (1) LV11624B (de)
MD (1) MD1374G2 (de)
MX (1) MX9603080A (de)
NO (1) NO317020B1 (de)
RU (1) RU2155190C2 (de)
WO (1) WO1995020605A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL129299A0 (en) * 1999-03-31 2000-02-17 Mor Research Applic Ltd Monoclonal antibodies antigens and diagnosis of malignant diseases
IL145926A0 (en) 2001-10-15 2002-07-25 Mor Research Applic Ltd Peptide epitopes of mimotopes useful in immunomodulation
IL149820A0 (en) 2002-05-23 2002-11-10 Curetech Ltd Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
ES2654064T3 (es) 2002-07-03 2024-03-13 Ono Pharmaceutical Co Composiciones inmunopotenciadoras que comprenden anticuerpos anti-PD-L1
DE10311248A1 (de) * 2003-03-14 2004-09-30 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper
US20090123413A1 (en) * 2004-08-23 2009-05-14 Britta Hardy Use of bat monoclonal antibody for immunotherapy
KR101339628B1 (ko) 2005-05-09 2013-12-09 메다렉스, 인코포레이티드 예정 사멸 인자 1(ｐｄ-1)에 대한 인간 모노클로날 항체, 및 항-ｐｄ-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법
KR101888321B1 (ko) 2005-07-01 2018-08-13 이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. 예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
PL2170959T3 (pl) 2007-06-18 2014-03-31 Merck Sharp & Dohme Przeciwciała przeciwko ludzkiemu receptorowi programowanej śmierci PD-1
CN101970499B (zh) 2008-02-11 2014-12-31 治疗科技公司 用于肿瘤治疗的单克隆抗体
MD3972C2 (ro) * 2009-03-11 2010-07-31 Ион МЕРЕУЦЭ Remediu şi metodă de tratament al stărilor precanceroase
EP2734551B1 (de) 2011-07-24 2018-01-10 Cure Tech Ltd. Varianten humanisierter immunmodulatorischer monoklonaler antikörper
WO2015048312A1 (en) 2013-09-26 2015-04-02 Costim Pharmaceuticals Inc. Methods for treating hematologic cancers
US9580504B1 (en) 2013-11-07 2017-02-28 Curetech Ltd. Pidilizumab monoclonal antibody therapy following stem cell transplantation
JOP20200094A1 (ar) 2014-01-24 2017-06-16 Dana Farber Cancer Inst Inc جزيئات جسم مضاد لـ pd-1 واستخداماتها
JOP20200096A1 (ar) 2014-01-31 2017-06-16 Children’S Medical Center Corp جزيئات جسم مضاد لـ tim-3 واستخداماتها
TWI693232B (zh) 2014-06-26 2020-05-11 美商宏觀基因股份有限公司 與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
RU2718914C2 (ru) 2014-09-13 2020-04-15 Новартис Аг Сочетанные способы лечения с использованием ингибиторов alk
TWI773646B (zh) 2015-06-08 2022-08-11 美商宏觀基因股份有限公司 結合lag-3的分子和其使用方法
IL297090A (en) 2015-07-30 2022-12-01 Macrogenics Inc Molecules that bind pd-1 and methods of using them
PE20181322A1 (es) 2015-09-01 2018-08-14 Agenus Inc Anticuerpo anti-pd1 y sus metodos de uso
EA201890790A1 (ru) 2015-09-29 2018-10-31 Селджин Корпорейшн Связывающие pd-1 белки и способы их применения
EP3370768B9 (de) 2015-11-03 2022-03-16 Janssen Biotech, Inc. Spezifisch an pd-1 bindende antikörper und deren verwendung
TW202208440A (zh) 2015-12-14 2022-03-01 美商宏觀基因股份有限公司 對於pd-1和ctla-4具有免疫反應性的雙特異性分子及其使用方法
EP3471754A1 (de) 2016-06-20 2019-04-24 Kymab Limited Anti-pd-l1-antikörper
WO2018053401A1 (en) 2016-09-19 2018-03-22 Celgene Corporation Methods of treating vitiligo using pd-1 binding proteins
MX2019002867A (es) 2016-09-19 2019-11-12 Celgene Corp Metodos de tratamiento de trastornos inmunologicos usando proteinas de union a pd-1.
JP7106538B2 (ja) 2016-12-07 2022-07-26 アジェナス インコーポレイテッド 抗体およびその使用方法
GB202107994D0 (en) 2021-06-04 2021-07-21 Kymab Ltd Treatment of cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182368A (en) * 1986-06-13 1993-01-26 Ledbetter Jeffrey A Ligands and methods for augmenting B-cell proliferation

Also Published As

Publication number Publication date
WO1995020605A1 (en) 1995-08-03
CN1145077A (zh) 1997-03-12
JP3478398B2 (ja) 2003-12-15
NO963168D0 (no) 1996-07-29
AU1868695A (en) 1995-08-15
MX9603080A (es) 1998-01-31
DE69504955D1 (de) 1998-10-29
IL108501A0 (en) 1994-05-30
CA2182289C (en) 2003-10-21
NO317020B1 (no) 2004-07-26
AU693526B2 (en) 1998-07-02
NO963168L (no) 1996-09-27
RU2155190C2 (ru) 2000-08-27
DE69504955T2 (de) 1999-05-27
IL108501A (en) 1998-10-30
MD1374F2 (en) 1999-12-31
JPH09508390A (ja) 1997-08-26
EP0742795B1 (de) 1998-09-23
DK0742795T3 (da) 1999-06-14
LT4225B (en) 1997-10-27
LV11624A (en) 1996-12-20
CN1052733C (zh) 2000-05-24
FI963004A0 (fi) 1996-07-29
EE03285B1 (et) 2000-08-15
CA2182289A1 (en) 1995-08-03
EP0742795A1 (de) 1996-11-20
LV11624B (en) 1997-06-20
FI963004A (fi) 1996-09-27
MD1374G2 (ro) 2000-09-30
US5897862A (en) 1999-04-27
ES2124533T3 (es) 1999-02-01
LT96115A (en) 1997-05-26

Similar Documents

Publication Publication Date Title
ATE171461T1 (de) Immunstimulierende monoklonale antikörper
DE69221147D1 (de) Nicht glycosylierter Anti-CD3-IgG-Antikörper
EP0597829A4 (de) Monoklonaler antikörper gegen einen neuen mit menschlichen tumoren assoziierten antigen.
DK666389D0 (da) Monoklonalt antistof
KR970702882A (ko) 암치료 및 암탐지를 위한 종양세포 생성 단백질의 모노클로날 항체(monoclonal antibody to oncofetal protein for treating and detecting cancer)
DE69319662T2 (de) Monoklonale Antikörper gegen GP130-Protein
DE68914244D1 (de) Monoklonaler Antikörper.
ATE267610T1 (de) Glykosylierte igg antikörper
ZA946767B (en) Monocional antibodies having property of causing apoptosis.
DE3885355D1 (de) Monoklonale Antikörper.
NZ305083A (en) Use of cd40 binding proteins (a cd40 ligand or monoclonal antibody that specifically binds to cd40) for stimulating a immune response
DE3586216D1 (de) Brusttumorassoziiertes antigen und monoklonale antikoerper dazu.
NO177311C (no) Anti-fucosylceramid monoklonalt antistoff
DE3888604D1 (de) Monoklonale Antikörper gegen Antithrombinbindende Substanz und seine Verwendungen.
DE3785795D1 (de) Monoklonale anti-menschliche magenkrebs-antikoerper.
DK49291D0 (da) Gramnegativ-bakterieendotoxinblokerende, monoklonale antistoffer
DE3580482D1 (de) Monoklonale antikoerper und immunisierung damit.
NO890116D0 (no) Monoklonale antistoffer.
DK413389D0 (da) Monoklonale antistoffer
DE68916088D1 (de) Anti-CPBII-monoklonaler Antikörper.
NO903788D0 (no) Monoklonalt antistoff mot protein c.
DK220688D0 (da) Monoklonalt antistof
NZ314010A (en) A method of targeting intracellular binding proteins using a lipidized antibody
NO914094D0 (no) Nytt monoklonalt antistoff mot nytt antigen forbundet medhumantumorer
ATE58173T1 (de) Monoklonale antikoerper und immunisierung damit.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification