IN186768B - - Google Patents

Info

Publication number
IN186768B
IN186768B IN2893DE1996A IN186768B IN 186768 B IN186768 B IN 186768B IN 2893DE1996 A IN2893DE1996 A IN 2893DE1996A IN 186768 B IN186768 B IN 186768B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Herve Bouchard
Alain Commercon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Priority to IN419DE2000 priority Critical patent/IN188680B/en
Publication of IN186768B publication Critical patent/IN186768B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN2893DE1996 1995-12-22 1996-12-20 IN186768B (index.php)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IN419DE2000 IN188680B (index.php) 1995-12-22 2000-04-10

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
IN186768B true IN186768B (index.php) 2001-11-03

Family

ID=9485871

Family Applications (4)

Application Number Title Priority Date Filing Date
IN2893DE1996 IN186768B (index.php) 1995-12-22 1996-12-20
IN419DE2000 IN188680B (index.php) 1995-12-22 2000-04-10
IN421DE2000 IN188470B (index.php) 1995-12-22 2000-04-10
IN420DE2000 IN188469B (index.php) 1995-12-22 2000-04-10

Family Applications After (3)

Application Number Title Priority Date Filing Date
IN419DE2000 IN188680B (index.php) 1995-12-22 2000-04-10
IN421DE2000 IN188470B (index.php) 1995-12-22 2000-04-10
IN420DE2000 IN188469B (index.php) 1995-12-22 2000-04-10

Country Status (40)

Country Link
US (1) US5728849A (index.php)
EP (1) EP0876362B1 (index.php)
JP (1) JP3953106B2 (index.php)
KR (1) KR100500351B1 (index.php)
CN (1) CN1103766C (index.php)
AR (1) AR005197A1 (index.php)
AT (1) ATE250593T1 (index.php)
AU (1) AU712597B2 (index.php)
BG (1) BG63204B1 (index.php)
BR (1) BR9612135A (index.php)
CA (1) CA2238884C (index.php)
CO (1) CO4520184A1 (index.php)
CZ (1) CZ294972B6 (index.php)
DE (1) DE69630145T2 (index.php)
DK (1) DK0876362T3 (index.php)
DZ (1) DZ2149A1 (index.php)
EA (1) EA001533B1 (index.php)
ES (1) ES2202490T3 (index.php)
FR (1) FR2742751B1 (index.php)
HU (1) HU225032B1 (index.php)
IL (1) IL124994A (index.php)
IN (4) IN186768B (index.php)
MA (1) MA26412A1 (index.php)
MX (1) MX9804688A (index.php)
MY (1) MY113934A (index.php)
NO (1) NO317358B1 (index.php)
NZ (1) NZ324337A (index.php)
OA (1) OA10700A (index.php)
PE (1) PE25198A1 (index.php)
PL (1) PL189311B1 (index.php)
PT (1) PT876362E (index.php)
RO (1) RO116194B1 (index.php)
SK (1) SK282835B6 (index.php)
TN (1) TNSN96169A1 (index.php)
TR (1) TR199801179T2 (index.php)
TW (1) TW371659B (index.php)
UA (1) UA48205C2 (index.php)
UY (1) UY24386A1 (index.php)
WO (1) WO1997023473A1 (index.php)
ZA (1) ZA9610737B (index.php)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
EP1165550A1 (en) 2000-02-02 2002-01-02 Florida State University Research Foundation, Inc. C10 carbonate substituted taxanes as antitumor agents
DE50209483D1 (de) * 2001-02-24 2007-03-29 Boehringer Ingelheim Pharma Xanthinderivate, deren herstellung und deren verwendung als arzneimittel
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US20080107721A1 (en) * 2003-05-20 2008-05-08 Jonathan Lewis Combination Chemotherapy Comprising A Liposomal Platinum Complex
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1669358A1 (en) * 2004-12-07 2006-06-14 Aventis Pharma S.A. Cytotoxic agents comprising new taxanes
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
NZ600394A (en) * 2006-05-04 2014-04-30 Boehringer Ingelheim Int Polymorphs of a dpp-iv enzyme inhibitor
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
NZ600126A (en) * 2007-08-17 2013-12-20 Boehringer Ingelheim Int Purine derivatives for use in the treatment of fap-related diseases
PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
BRPI0916997A2 (pt) 2008-08-06 2020-12-15 Boehringer Ingelheim International Gmbh Inibidor de dpp-4 e seu uso
BRPI0917675A2 (pt) * 2008-08-15 2015-12-01 Boehringer Ingelheim Int compostos orgânicos para cura de ferida
WO2010029089A2 (en) 2008-09-10 2010-03-18 Boehringer Ingelheim International Gmbh Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
KR20110103968A (ko) 2008-12-23 2011-09-21 베링거 인겔하임 인터내셔날 게엠베하 유기 화합물의 염 형태
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
KR20190071840A (ko) 2009-11-27 2019-06-24 베링거 인겔하임 인터내셔날 게엠베하 리나글립틴과 같은 ｄｐｐ－ｉｖ 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료
PH12012502162A1 (en) 2010-05-05 2013-02-04 Boehringer Ingelheim Int Combination therapy
EP2585101A1 (en) 2010-06-24 2013-05-01 Boehringer Ingelheim International GmbH Diabetes therapy
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
EP3517539B1 (en) 2011-07-15 2022-12-14 Boehringer Ingelheim International GmbH Substituted dimeric quinazoline derivative, its preparation and its use in pharmaceutical compositions for the treatment of type i and ii diabetes
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
WO2013171167A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
EP2849754B1 (en) 2012-05-14 2022-09-14 Boehringer Ingelheim International GmbH Linagliptin, a xanthine derivative as dpp-4 inhibitor, for use in the treatment of sirs and/or sepsis
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
US10131682B2 (en) 2012-11-24 2018-11-20 Hangzhou Dac Biotech Co., Ltd. Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules
FR3010839B1 (fr) * 2013-09-17 2017-04-21 Schneider Electric Ind Sas Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique
US9526728B2 (en) 2014-02-28 2016-12-27 Boehringer Ingelheim International Gmbh Medical use of a DPP-4 inhibitor
CN106414465B (zh) 2014-02-28 2021-11-16 杭州多禧生物科技有限公司 带电荷链接体及其在共轭反应上的应用
EP4678240A2 (en) 2015-07-12 2026-01-14 Hangzhou Dac Biotech Co., Ltd. Bridge linkers for conjugation of cell-binding molecules
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
KR102391564B1 (ko) 2016-06-10 2022-04-29 베링거 인겔하임 인터내셔날 게엠베하 리나글립틴 및 메트포르민의 병용물
KR20220150408A (ko) 2016-11-14 2022-11-10 항저우 디에이씨 바이오테크 씨오, 엘티디 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
JP2024541058A (ja) 2021-11-03 2024-11-06 ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ． 抗体の特異的共役

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
ATE181551T1 (de) * 1992-04-17 1999-07-15 Abbott Lab Taxol-derivate
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
MX9307777A (es) * 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.

Also Published As

Publication number Publication date
US5728849A (en) 1998-03-17
TW371659B (en) 1999-10-11
EA001533B1 (ru) 2001-04-23
IN188469B (index.php) 2002-09-28
JP3953106B2 (ja) 2007-08-08
AU1180997A (en) 1997-07-17
ATE250593T1 (de) 2003-10-15
DE69630145T2 (de) 2004-07-15
FR2742751A1 (fr) 1997-06-27
NO317358B1 (no) 2004-10-18
SK85398A3 (en) 1998-11-04
CZ196198A3 (cs) 1998-09-16
MX9804688A (es) 1998-10-31
KR19990076680A (ko) 1999-10-15
UA48205C2 (uk) 2002-08-15
BG102569A (en) 1999-04-30
OA10700A (fr) 2002-11-27
UY24386A1 (es) 2001-08-27
SK282835B6 (sk) 2002-12-03
HU225032B1 (en) 2006-05-29
EP0876362A1 (fr) 1998-11-11
PE25198A1 (es) 1998-05-10
KR100500351B1 (ko) 2005-12-21
EP0876362B1 (fr) 2003-09-24
MY113934A (en) 2002-06-29
CO4520184A1 (es) 1997-10-15
ES2202490T3 (es) 2004-04-01
MA26412A1 (fr) 2004-12-20
WO1997023473A1 (fr) 1997-07-03
CA2238884A1 (fr) 1997-07-03
NO982580L (no) 1998-06-05
EA199800588A1 (ru) 1998-12-24
CN1103766C (zh) 2003-03-26
PL189311B1 (pl) 2005-07-29
CZ294972B6 (cs) 2005-04-13
BG63204B1 (bg) 2001-06-29
PT876362E (pt) 2004-02-27
HUP9904046A1 (hu) 2001-04-28
IL124994A0 (en) 1999-01-26
TNSN96169A1 (fr) 2005-03-15
ZA9610737B (en) 1997-06-27
HK1017895A1 (en) 1999-12-03
TR199801179T2 (xx) 1998-10-21
HUP9904046A3 (en) 2001-08-28
DK0876362T3 (da) 2004-02-02
IN188470B (index.php) 2002-09-28
PL327405A1 (en) 1998-12-07
IL124994A (en) 2000-12-06
NO982580D0 (no) 1998-06-05
DE69630145D1 (de) 2003-10-30
RO116194B1 (ro) 2000-11-30
AR005197A1 (es) 1999-04-14
BR9612135A (pt) 1999-07-13
IN188680B (index.php) 2002-10-26
AU712597B2 (en) 1999-11-11
CA2238884C (fr) 2007-02-06
NZ324337A (en) 2000-03-27
JP2000502671A (ja) 2000-03-07
DZ2149A1 (fr) 2002-10-23
CN1205697A (zh) 1999-01-20
FR2742751B1 (fr) 1998-01-30

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