IN169332B - - Google Patents

Info

Publication number
IN169332B
IN169332B IN920/CAL/87A IN920CA1987A IN169332B IN 169332 B IN169332 B IN 169332B IN 920CA1987 A IN920CA1987 A IN 920CA1987A IN 169332 B IN169332 B IN 169332B
Authority
IN
India
Application number
IN920/CAL/87A
Other languages
English (en)
Inventor
Dennis Earl Mccabe
William Foster Swain
Brian Joseph Martinell
Original Assignee
Agracetus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agracetus filed Critical Agracetus
Publication of IN169332B publication Critical patent/IN169332B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8206—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated
    • C12N15/8207—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated by mechanical means, e.g. microinjection, particle bombardment, silicon whiskers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
IN920/CAL/87A 1986-12-05 1987-11-24 IN169332B (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93857086A 1986-12-05 1986-12-05

Publications (1)

Publication Number Publication Date
IN169332B true IN169332B (ja) 1991-09-28

Family

ID=25471606

Family Applications (1)

Application Number Title Priority Date Filing Date
IN920/CAL/87A IN169332B (ja) 1986-12-05 1987-11-24

Country Status (12)

Country Link
EP (1) EP0270356B1 (ja)
JP (1) JP2606856B2 (ja)
CN (1) CN1016574B (ja)
AT (1) ATE106450T1 (ja)
AU (1) AU610534B2 (ja)
BR (1) BR8706531A (ja)
CA (1) CA1339901C (ja)
DE (1) DE3789941T2 (ja)
ES (1) ES2056830T3 (ja)
IL (1) IL84459A (ja)
IN (1) IN169332B (ja)
NZ (1) NZ222722A (ja)

Families Citing this family (266)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100792A (en) * 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
US4945050A (en) * 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5036006A (en) * 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5120657A (en) * 1986-12-05 1992-06-09 Agracetus, Inc. Apparatus for genetic transformation
US5015580A (en) * 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
EP0275069A3 (en) * 1987-01-13 1990-04-25 DNA PLANT TECHNOLOGY CORPORATION (under the laws of the state of Delaware) Pollen-mediated gene transformation in plants
IL82153A (en) * 1987-04-09 1991-12-15 Yissum Res Dev Co Process for introducing genes into plants
DK240088A (da) * 1987-05-05 1988-11-06 Sandoz Ag Fremgangsmaade til transformation af et plantecellematerale
US5371003A (en) * 1987-05-05 1994-12-06 Sandoz Ltd. Electrotransformation process
ES2121803T3 (es) * 1987-05-20 1998-12-16 Novartis Ag Plantas de zea mays y plantas transgenicas de zea mays generadas a partir de protoplastos o celulas derivadas de protoplastos.
US5350689A (en) * 1987-05-20 1994-09-27 Ciba-Geigy Corporation Zea mays plants and transgenic Zea mays plants regenerated from protoplasts or protoplast-derived cells
US5840557A (en) * 1987-07-21 1998-11-24 Mogen International Nv Method for producing seeds and plants thereof involving an in vitro step
CA1327173C (en) * 1987-07-21 1994-02-22 Erwin Heberle-Bors Method of gene transfer into plants
US5179022A (en) * 1988-02-29 1993-01-12 E. I. Du Pont De Nemours & Co. Biolistic apparatus for delivering substances into cells and tissues in a non-lethal manner
US5990387A (en) * 1988-06-10 1999-11-23 Pioneer Hi-Bred International, Inc. Stable transformation of plant cells
ATE195218T1 (de) * 1988-06-20 2000-08-15 Novartis Erfind Verwalt Gmbh Verfahren zur bekämpfung von pflanzenschädlingen mit nicht-pflanzlichen proteinase-inhibitoren
JPH04500153A (ja) * 1988-07-29 1992-01-16 ザ・ワシントン・ユニバーシティ 遺伝的に形質転換された内乳組織を有する商品価値のあるポリペプチドの産生
CA1341467C (en) * 1988-07-29 2004-12-07 John C. Rogers Producing commercially valuable polypeptides with genetically transformed endosperm tissue
US5428001A (en) * 1988-11-10 1995-06-27 Regents Of The University Of Minnesota Method for combating weeds among maize plants
US5162602A (en) * 1988-11-10 1992-11-10 Regents Of The University Of Minnesota Corn plants tolerant to sethoxydim and haloxyfop herbicides
US5290696A (en) * 1988-11-10 1994-03-01 Regents Of The University Of Minnesota Method for imparting cyclohexanedione and/or aryloxyphenoxypropanioc acid herbicide tolerance to maize plants
US5629183A (en) * 1989-05-08 1997-05-13 The United States Of America As Represented By The Secretary Of Agriculture Plant transformation by gene transfer into pollen
US5122466A (en) * 1989-06-13 1992-06-16 North Carolina State University Ballistic transformation of conifers
DK0431135T3 (da) * 1989-06-26 2003-07-21 Powderject Vaccines Inc Partikelmedieret transformation af somatiske dyreceller
CA2019989A1 (en) * 1989-06-28 1990-12-28 Jon C. Mitchell Suspension culture of haploid maize gametophytes and products therefrom
US5141131A (en) * 1989-06-30 1992-08-25 Dowelanco Method and apparatus for the acceleration of a propellable matter
US5240842A (en) * 1989-07-11 1993-08-31 Biotechnology Research And Development Corporation Aerosol beam microinjector
JPH05501352A (ja) * 1989-08-09 1993-03-18 ディカルブ　ジェネティクス　コーポレイション 安定な形質転換稔性単子葉植物およびそれらの細胞を製造するための方法および組成物
US6803499B1 (en) 1989-08-09 2004-10-12 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US7705215B1 (en) 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5550318A (en) * 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
DE69031951T2 (de) 1989-11-16 1998-08-13 Cornell Res Foundation Inc Transformation von tierischen Hautzellen mit hilfe von Partikeln
ATE130371T1 (de) * 1989-12-19 1995-12-15 Ciba Geigy Ag Verfahren und vorrichtung zur genetischen transformation von zellen.
US6329574B1 (en) 1990-01-22 2001-12-11 Dekalb Genetics Corporation High lysine fertile transgenic corn plants
US6946587B1 (en) 1990-01-22 2005-09-20 Dekalb Genetics Corporation Method for preparing fertile transgenic corn plants
US6777589B1 (en) 1990-01-22 2004-08-17 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5484956A (en) * 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
HU220773B1 (hu) * 1990-01-22 2002-05-28 Dekalb Genetics Corporation Eljárás termő transzgenikus kukoricanövények előállítására
US5066587A (en) * 1990-01-26 1991-11-19 The Upjohn Company Gas driven microprojectile accelerator and method of use
EP0442174A1 (en) * 1990-02-13 1991-08-21 Pioneer Hi-Bred International, Inc. Stable transformation of plant cells
US5204253A (en) * 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US5149655A (en) * 1990-06-21 1992-09-22 Agracetus, Inc. Apparatus for genetic transformation
AU8418091A (en) * 1990-07-19 1992-02-18 Chris Brinegar Methods and apparatus for ice-medicated introduction of substances into biological material in a non-lethal manner
US5219746A (en) * 1990-07-19 1993-06-15 Chris Brinegar Ice-mediated introduction of substances into biological material
US6395966B1 (en) 1990-08-09 2002-05-28 Dekalb Genetics Corp. Fertile transgenic maize plants containing a gene encoding the pat protein
AU643563B2 (en) * 1990-11-01 1993-11-18 Sapporo Breweries Limited Method for preparing transformed plant
WO1993008292A1 (en) * 1991-10-16 1993-04-29 Agracetus, Inc. Particle-mediated transformation of animal somatic cells
US5449855A (en) * 1992-01-24 1995-09-12 Dekalb Plant Genetics Methods and compositions of a hybrid genetic corn complement, DK743
US5424483A (en) * 1992-01-24 1995-06-13 Dekalb Plant Genetics Methods and compositions of a hybrid genetic corn complement, DK554
JPH07509139A (ja) * 1992-07-30 1995-10-12 インターナショナル　フラワー　ディベロップメンツ　プロプライアタリー　リミティド グリコシルトランスフェラーゼ酵素をコードする遺伝子配列およびその用途
US6222099B1 (en) 1993-02-05 2001-04-24 Regents Of The University Of Minnesota Transgenic plants expressing maize acetyl COA carboxylase gene and method of altering oil content
US6414222B1 (en) 1993-02-05 2002-07-02 Regents Of The University Of Minnesota Gene combinations for herbicide tolerance in corn
US6069298A (en) * 1993-02-05 2000-05-30 Regents Of The University Of Minnesota Methods and an acetyl CoA carboxylase gene for conferring herbicide tolerance and an alteration in oil content of plants
US6118047A (en) 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
US5780709A (en) * 1993-08-25 1998-07-14 Dekalb Genetics Corporation Transgenic maize with increased mannitol content
DK0690732T3 (da) * 1994-01-21 2003-05-19 Powderject Vaccines Inc Gasdrevet genindførselsinstrument
CN1035304C (zh) * 1994-04-07 1997-07-02 丁群星 转化植物的方法及装置
US5910635A (en) * 1995-02-03 1999-06-08 Dekalb Genetics Corporation Inbred corn plant 91DFA-5
US6372969B1 (en) 1995-02-03 2002-04-16 Dekalb Genetics Corporation Inbred corn plant NL054B and seeds thereof
EP0757102A1 (en) 1995-08-04 1997-02-05 Plant Genetic Systems N.V. Genetic transformation using a PARP inhibitor
US5910625A (en) * 1996-02-01 1999-06-08 Dekalb Genetics Corporation Inbred corn plant 3AZA1 and seeds thereof
US5977455A (en) * 1996-04-02 1999-11-02 Dekalb Genetics Corporation Inbred corn plants WKBC5, and seeds thereof
US5856614A (en) 1996-04-08 1999-01-05 Dekalb Genetics Corporation Inbred corn plants 01IZB2 and seeds thereof
US5977452A (en) * 1996-04-08 1999-11-02 Dekalb Genetics Corporation Inbred corn plant 01IBH10
US5902922A (en) * 1997-02-05 1999-05-11 Dekalb Genetics Corporation Inbred corn plant FEBS and seeds thereof
US6133512A (en) * 1997-02-05 2000-10-17 Dekalb Genetics Corporation Inbred corn plant 17DHD5 and seeds thereof
US5880342A (en) * 1997-02-05 1999-03-09 Dekalb Genetics Corporation Inbred corn plant 17DIA1 and seeds thereof
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US6433154B1 (en) * 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
WO1999007210A1 (en) 1997-08-12 1999-02-18 North Carolina State University Genetically engineered duckweed
US6111171A (en) * 1998-01-26 2000-08-29 Dekalb Genetics Corporation Inbred corn plant 90LCL6 and seeds thereof
US5932788A (en) * 1998-01-26 1999-08-03 Dekalb Genetics Corporation Inbred corn plant 86ISI3 and seeds thereof
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US6046387A (en) * 1998-01-30 2000-04-04 Dekalb Genetics Corporation Inbred corn plant 17dhd7 and seeds thereof
US6072108A (en) * 1998-01-30 2000-06-06 Dekalb Genetics Corporation Inbred corn plant 09DSQ1 and seeds thereof
US6043417A (en) * 1998-01-30 2000-03-28 Dekalb Genetics Corporation Inbred corn plant 79314N1 and seeds thereof
US6031162A (en) * 1998-01-30 2000-02-29 Dekalb Genetics Corporation Inbred corn plant 90LDI1 and seeds thereof
US6034304A (en) * 1998-02-02 2000-03-07 Dekalb Genetics Corporation Inbred corn plant 90LDC2 and seeds thereof
US6037531A (en) * 1998-02-02 2000-03-14 Dekalb Genetics Corporation Inbred corn plant RDBQ2 and seeds thereof
US6034305A (en) * 1998-02-03 2000-03-07 Dekalb Genetics Corporation Inbred corn plant 90QDD1 and seeds thereof
US6031161A (en) * 1998-02-04 2000-02-29 Dekalb Genetics Corporation Inbred corn plant GM9215 and seeds thereof
US5936146A (en) * 1998-02-05 1999-08-10 Dekalb Genetics Corporation Inbred corn plant 79310J2 and seeds thereof
US5962770A (en) * 1998-02-05 1999-10-05 Dekalb Genetics Corporation Inbred corn plant 91DHA1 and seeds thereof
US5965799A (en) * 1998-02-05 1999-10-12 Dekalb Genetics Corporation Inbred corn plant 91ISI4 and seeds thereof
US5994631A (en) * 1998-02-05 1999-11-30 Dekalb Genetics Corporation Inbred corn plant WQDS2 and seeds thereof
US5922936A (en) * 1998-02-05 1999-07-13 Dekalb Genetics Corporation Inbred corn plant 8M222 and seeds thereof
US5939606A (en) * 1998-02-05 1999-08-17 Dekalb Genetics Corporation Inbred corn plant 01DHD10 and seeds thereof
US5912421A (en) * 1998-02-05 1999-06-15 Dekalb Genetics Corporation Inbred corn plant 91ISI6 and seeds thereof
US6031160A (en) * 1998-02-06 2000-02-29 Dekalb Genetics Corporation Inbred corn plant 7OLDL5 and seeds thereof
FR2777016B1 (fr) * 1998-04-06 2002-06-14 Rhone Poulenc Agrochimie Silicone azotee utile pour compacter les sequences d'acides nucleiques et utilisation pour la transfection
WO1999053050A1 (en) 1998-04-08 1999-10-21 Commonwealth Scientific And Industrial Research Organisation Methods and means for obtaining modified phenotypes
JP4474496B2 (ja) 1998-06-02 2010-06-02 学校法人日本大学 ＩｇＡ腎症関連ＤＮＡ
AU1619400A (en) 1998-11-10 2000-05-29 Maxygen, Inc. Modified adp-glucose pyrophosphorylase for improvement and optimization of plantphenotypes
US6043418A (en) * 1999-01-13 2000-03-28 Dekalb Genetics Corporation Inbred corn plant 17INI20 and seeds thereof
US6040508A (en) * 1999-01-14 2000-03-21 Dekalb Genetics Corporation Inbred corn plant 01HG12 and seeds thereof
US6046389A (en) * 1999-01-14 2000-04-04 Dekalb Genetics Corporation Inbred corn plant 83InI14 and seeds thereof
US6046390A (en) * 1999-01-14 2000-04-04 Dekalb Genetics Corporation Inbred corn plant 01INL1 and seeds thereof
US6114611A (en) * 1999-01-14 2000-09-05 Dekalb Genetics Corporation Inbred corn plant WDHQ2 and seeds thereof
US6084162A (en) * 1999-01-14 2000-07-04 Dekalb Genetics Corporation Inbred corn plant 86ISI15 and seeds thereof
US6046388A (en) * 1999-01-14 2000-04-04 Dekalb Genetics Corporation Inbred corn plant 83INI8 and seeds thereof
US6077999A (en) * 1999-01-14 2000-06-20 Dekalb Genetics Corporation Inbred corn plant 86AQV2 and seeds thereof
US6096952A (en) * 1999-01-14 2000-08-01 Dekalb Genetics Corporation Inbred corn plant 01DHD16 and seeds thereof
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US6239334B1 (en) 1999-01-14 2001-05-29 Dekalb Genetics Corporation Inbred corn plant F351 and seeds thereof
US6303850B1 (en) 1999-01-14 2001-10-16 Dekalb Genetics Corporation Inbred corn plant 09DSS1 and seeds thereof
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US6225538B1 (en) 1999-02-16 2001-05-01 Dekalb Genetics Corporation Inbred corn plant 89ADH11 and seeds thereof
US6215050B1 (en) 1999-02-16 2001-04-10 Dekalb Genetics Corp. Inbred corn plant 91INI12 and seeds thereof
US6232535B1 (en) 1999-02-16 2001-05-15 Dekalb Genetics Corporation Inbred corn plant 16IUL2 seeds thereof
US6222105B1 (en) 1999-02-16 2001-04-24 Dekalb Genetics Corp. Inbred corn plant 86ISI26 and seeds thereof
US6353160B1 (en) 1999-02-16 2002-03-05 Dekalb Genetics Corp. Inbred corn plant 4SCQ3 and seeds thereof
US6222106B1 (en) 1999-02-23 2001-04-24 Dekalb Genetics Group Inbred corn plant 01IUL6 and seeds thereof
US6355867B1 (en) 1999-02-23 2002-03-12 Dekalb Genetics Corporation Inbred corn plant 87ATD2 and seeds thereof
US6248941B1 (en) 1999-02-23 2001-06-19 Dekalb Genetics Corporation Inbred corn plant 17DHD16 and seeds thereof
US6211446B1 (en) 1999-02-23 2001-04-03 Dekalb Genetics Corp. Inbred corn plant 91ISI5 and seeds thereof
US6229076B1 (en) 1999-02-26 2001-05-08 Dekalb Genetics Corporation Inbred corn plant 01HGI4 and seeds thereof
US6291748B1 (en) 1999-02-26 2001-09-18 Dekalb Genetics Corporation Inbred corn plant WDHQ11 and seeds thereof
US6365805B1 (en) 1999-03-08 2002-04-02 Dekalb Genetics Corporation Inbred corn plant 83DNQ2 and seeds thereof
JP4623825B2 (ja) 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
BR0016851A (pt) 1999-12-28 2002-10-08 Bayer Crospscience N V Proteìnas inseticidas do bacillus thuringiensis
US6340786B1 (en) 2000-01-31 2002-01-22 Dekalb Genetics Corporation Inbred corn plant 17INI30 and seeds thereof
US6437224B1 (en) 2000-01-31 2002-08-20 Asgrow Seed Company, Llc Inbred corn plant 3323 and seeds thereof
US6365806B1 (en) 2000-01-31 2002-04-02 Dekalb Genetics Corporation Inbred corn plant 94INK1A and seeds thereof
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US6441280B2 (en) 2000-02-18 2002-08-27 Dekalb Genetics Corporation Inbred corn plant 16IUL6 and seeds thereof
US6756527B2 (en) 2000-02-24 2004-06-29 Asgrow Seed Company Llc Inbred corn plant 5750 and seeds thereof
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US6455764B2 (en) 2000-02-24 2002-09-24 Dekalb Genetics Corporation Inbred corn plant WQDS7 and seeds thereof
US6444883B2 (en) 2000-02-24 2002-09-03 Asgrow Seed Company Llc Inbred corn plant 6077 and seeds thereof
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US6429363B1 (en) 2000-03-03 2002-08-06 Dekalb Genetics Corporation Inbred corn plant 94INK1B and seeds thereof
US6806399B1 (en) * 2000-04-19 2004-10-19 Carmel-Haifa University Economic Corporation Ltd. Pollen-mediated method for transformation of maize, tomato or melon
WO2001087491A1 (en) 2000-05-16 2001-11-22 Regents Of The University Of Minnesota High mass throughput particle generation using multiple nozzle spraying
US7205459B1 (en) 2000-06-28 2007-04-17 Dekalb Genetics Corporation Transformable inbred corn line LIZL5 and methods for use thereof
HU231090B1 (hu) 2000-10-06 2020-07-28 Kyowa Kirin Co., Ltd. Antitest-kompozíciót termelő sejt
EP1988099B1 (en) 2001-01-09 2012-11-14 Bayer CropScience NV Bacillus thuringiensis insecticidal proteins
US7169981B2 (en) 2001-01-29 2007-01-30 Dekalb Genetics Corporation Plants and seeds of corn variety 1015036
US6420637B1 (en) 2001-01-29 2002-07-16 Asgrow Seed Company L.L.C. Plants and seeds of corn variety I389972
US6444884B1 (en) 2001-01-29 2002-09-03 Dekalb Genetics Corporation Plants and seeds of corn variety I014738
US7205460B2 (en) 2001-01-29 2007-04-17 Dekalb Genetics Corporation Plants and seeds of corn variety I026458
US6459022B1 (en) 2001-01-29 2002-10-01 Dekalb Genetics Corporation Plants and seeds of corn variety I465837
US6492581B1 (en) 2001-01-29 2002-12-10 Dekalb Genetics Corporation Plants and seeds of corn variety I362697
US6433262B1 (en) 2001-01-29 2002-08-13 Dekalb Genetics Corporation Plants and seeds of corn variety I889291
US7279624B2 (en) 2001-02-16 2007-10-09 Dekalb Genetics Corporation Plants and seeds of corn variety I015011
US6476299B1 (en) 2001-02-16 2002-11-05 Dekalb Genetics Corporation Plants and seeds of corn variety I181664
SG135907A1 (en) 2001-03-15 2007-10-29 Sumitomo Chemical Co Analysis of agonist-activity and antagonist-activity to cytokinin receptor
US7247338B2 (en) 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
WO2003040370A1 (fr) 2001-10-19 2003-05-15 Sumitomo Chemical Company, Limited Proteines du metabolisme permettant de lutter contre les mauvaises herbes, leurs genes et leur utilisation
DE10212892A1 (de) 2002-03-20 2003-10-09 Basf Plant Science Gmbh Konstrukte und Verfahren zur Regulation der Genexpression
CN100497378C (zh) 2002-03-22 2009-06-10 拜尔生物科学公司 新的苏云金芽孢杆菌杀昆虫蛋白质
WO2004013333A2 (de) 2002-07-26 2004-02-12 Basf Plant Science Gmbh Revertierung der negativ-selektiven wirkung von negativen markerproteinen als selektionsverfahren
CA2497338A1 (en) 2002-08-30 2004-03-18 Japan Science And Technology Corporation Method of targeted gene disruption, genome of hyperthermostable bacterium and genome chip using the same
WO2004058960A1 (ja) 2002-12-26 2004-07-15 Kyowa Hakko Kogyo Co., Ltd. ジペプチドの製造法
IL157538A0 (en) 2003-08-21 2004-03-28 Bar Ilan Res & Dev Company Ltd Plant resistant to cytoplasm-feeding parasites
CA2604807C (en) 2005-04-19 2018-06-12 Basf Plant Science Gmbh Improved methods controlling gene expression
US8173871B2 (en) 2005-07-08 2012-05-08 Universidad Nacional Autonoma De Mexico Bacterial proteins with pesticidal activity
WO2007039454A1 (en) 2005-09-20 2007-04-12 Basf Plant Science Gmbh Methods for controlling gene expression using ta-siran
US20090270314A1 (en) 2005-09-29 2009-10-29 Tohoku University Polypeptide having anti-angiogenic activity
CA2637883C (en) 2006-01-31 2015-07-07 Regents Of The University Of Minnesota Electrospray coating of objects
US9248217B2 (en) 2006-01-31 2016-02-02 Nanocopocia, LLC Nanoparticle coating of surfaces
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
WO2007107302A2 (en) 2006-03-21 2007-09-27 Bayer Bioscience N.V. Novel genes encoding insecticidal proteins
JP5242382B2 (ja) 2006-04-14 2013-07-24 株式会社医学生物学研究所 エフェクター機能を有するポリペプチド変異体
US7927874B2 (en) 2006-05-16 2011-04-19 Mitsubishi Gas Chemical Company, Inc. Method of transferring substance into cell
EP2067857B1 (en) 2006-09-25 2012-04-11 Kyowa Hakko Bio Co., Ltd Method for production of dipeptide
US9040816B2 (en) 2006-12-08 2015-05-26 Nanocopoeia, Inc. Methods and apparatus for forming photovoltaic cells using electrospray
US20110236374A1 (en) 2007-01-24 2011-09-29 Kyowa Hakko Kirin Co., Ltd. Genetically recombinant antibody composition capable of binding specifically to ganglioside gm2
JP5071942B2 (ja) 2007-01-24 2012-11-14 協和発酵キリン株式会社 エフェクター活性が増強された遺伝子組換え抗体組成物
US20100075343A1 (en) 2007-01-25 2010-03-25 Motoo Yamasaki Novel peptides
CN101605896A (zh) 2007-02-06 2009-12-16 巴斯福植物科学有限公司 使用rna干扰控制线虫的组合物和方法
ATE553195T1 (de) 2007-02-08 2012-04-15 Basf Plant Science Gmbh Zusammensetzungen und verfahren mit rna- interferenz opr3-ähnlichem gen zur kontrolle von nematoden
CN101631867A (zh) 2007-02-09 2010-01-20 巴斯福植物科学有限公司 用cdpk-样基因的rna干扰控制线虫的组合物和方法
CN101679995A (zh) 2007-03-15 2010-03-24 巴斯福植物科学有限公司 线虫几丁质酶基因用于控制植物寄生性线虫的用途
CN101688216B (zh) 2007-06-01 2014-03-26 拜尔作物科学公司 编码杀虫蛋白质的新基因
JP5550041B2 (ja) 2007-09-27 2014-07-16 塩野義製薬株式会社 チトクロームｐ４５０を用いたアダマンタン水酸化体の製造方法
EP2230300A4 (en) 2007-10-24 2012-08-08 Otsuka Chemical Holdings Co Ltd POLYPEPTIDE WITH IMPROVED EFFECTOR FUNCTION
EP2554674B1 (en) 2007-12-21 2014-11-05 Keygene N.V. Trichome specific promoters
CN101280315B (zh) 2008-05-20 2010-09-01 中国农业科学院油料作物研究所 毛白杨木质素单体合成基因4-cl及应用
EP2311864A4 (en) 2008-08-13 2013-07-31 Kyowa Hakko Kirin Co Ltd RECOMBINANT PROTEIN-S COMPOSITION
BRPI0917371A2 (pt) 2008-08-27 2015-11-17 Basf Plant Science Gmbh planta trangênica transformada com um vetor de expressão, semente, vetor de expressão, e, método para produzir uma planta trangênica resistente a nematóides.
EP2357228B1 (en) 2008-10-09 2017-05-10 Kyowa Medex CO., LTD. Novel fructosyl peptide oxidase
DE112009003576T5 (de) 2008-12-11 2012-09-06 Basf Plant Science Gmbh Pflanzenwurzel-spezifische Nematodenresistenz
CA2754956A1 (en) 2009-03-20 2010-09-23 Basf Plant Science Company Gmbh Nematode-resistant transgenic plants
JP5737828B2 (ja) * 2009-03-23 2015-06-17 パール工業株式会社 標的細胞または標的組織内への選定分子導入方法、それに用いる導入装置、標的細胞の細胞融合方法およびそれに用いる細胞融合装置
ES2879599T3 (es) 2009-06-08 2021-11-22 Nunhems Bv Plantas tolerantes a la sequía
JP2012531216A (ja) 2009-07-01 2012-12-10 バイエル・クロップサイエンス・エヌ・ヴェー グリホサート耐性が増強された植物を得るための方法および手段
US20120151629A1 (en) 2009-08-25 2012-06-14 Basf Plant Science Company Gmbh Nematode-Resistant Transgenic Plants
CA2781693C (en) 2009-11-27 2018-12-18 Basf Plant Science Company Gmbh Chimeric endonucleases and uses thereof
CN102725412B (zh) 2009-11-27 2017-09-22 巴斯夫植物科学有限公司 优化的内切核酸酶及其用途
BR112012013713B1 (pt) 2009-12-09 2023-12-12 Basf Plant Science Company Gmbh Método para produzir uma planta e/ou uma parte dessa resistente a um fungo, construção de vetor e uso da construção de vetor
BR112012019609A2 (pt) 2010-02-23 2019-09-24 Basf Plant Science Gmbh vetor de expressão isolado , plantas,transgenicas metodo para produzir uma planta transgenica e metodo para conferir a resistencia a nematoides em uma planta
CA2791652C (en) 2010-03-02 2018-06-12 Kyowa Hakko Kirin Co., Ltd. Modified antibody composition
EP2554669B1 (en) 2010-03-26 2018-09-19 Kyowa Hakko Kirin Co., Ltd. Novel antibody having modification site introduced therein, and antibody fragment
US20130145499A1 (en) 2010-05-28 2013-06-06 Willem Hendrik Vriezen Plants with Increased Fruit Size
WO2012004013A2 (en) 2010-07-08 2012-01-12 Bayer Bioscience N.V. Glucosinolate transporter protein and uses thereof
JP5058332B2 (ja) 2010-07-14 2012-10-24 住友ゴム工業株式会社 イソプレンオリゴマー、ポリイソプレン、及びこれらの製造方法、ゴム組成物、並びに空気入りタイヤ
WO2012084756A1 (en) 2010-12-20 2012-06-28 Basf Plant Science Company Gmbh Nematode-resistant transgenic plants
EP2535416A1 (en) 2011-05-24 2012-12-19 BASF Plant Science Company GmbH Development of phytophthora resistant potato with increased yield
US9234193B2 (en) 2011-05-31 2016-01-12 Keygene N.V. Pest resistant plants
CN104053770A (zh) 2011-10-19 2014-09-17 凯金公司 用于产生肉桂酸内酯和/或补身二醇的方法
EP2612918A1 (en) 2012-01-06 2013-07-10 BASF Plant Science Company GmbH In planta recombination
WO2013116750A1 (en) 2012-02-02 2013-08-08 Conicet HaHB11 PROVIDES IMPROVED PLANT YIELD AND TOLERANCE TO ABIOTIC STRESS
HUP1400495A2 (en) 2012-03-13 2015-03-02 Univ Guelph Guelph Ontario Methods of increasing tolerance to heat stress and amino acid content of plants
WO2013136274A1 (en) 2012-03-13 2013-09-19 University Of Guelph Myb55 promoter and use thereof
EP2905290B1 (en) 2012-10-05 2019-12-04 Kyowa Kirin Co., Ltd. Heterodimeric protein composition
US10435705B2 (en) 2013-01-29 2019-10-08 Basf Plant Science Company Gmbh Fungal resistant plants expressing HCP6
CA2897482A1 (en) 2013-01-29 2014-08-07 Basf Plant Science Company Gmbh Fungal resistant plants expressing hcp7
US10231397B2 (en) 2013-01-29 2019-03-19 Basf Plant Science Company Gmbh Fungal resistant plants expressing EIN2
CN105008542B (zh) 2013-03-08 2020-02-07 巴斯夫植物科学有限公司 表达MybTF的抗真菌性植物
WO2014142647A1 (en) 2013-03-14 2014-09-18 Wageningen Universiteit Fungals strains with improved citric acid and itaconic acid production
US9944970B2 (en) 2013-07-09 2018-04-17 Kyowa Medex Co., Ltd. Glycated hexapeptide oxidase and use thereof
CN105518136A (zh) 2013-07-10 2016-04-20 巴斯夫欧洲公司 用于通过抑制CYP51基因表达来控制致植物病真菌和卵菌的RNAi
JP6448194B2 (ja) 2014-01-20 2019-01-09 住友ゴム工業株式会社 シス型プレニルトランスフェラーゼをコードする遺伝子、及び、ＮｏｇｏＢｒｅｃｅｐｔｏｒをコードする遺伝子を宿主に導入することにより、該宿主において、シス型プレニルトランスフェラーゼ及びＮｏｇｏＢｒｅｃｅｐｔｏｒを発現させた形質転換体、並びに該形質転換体を用いたポリイソプレノイドの製造方法
CN104186305B (zh) * 2014-08-21 2016-05-25 山东省农业科学院玉米研究所 一种玉米人工辅助授粉器具
WO2016124515A1 (en) 2015-02-04 2016-08-11 Basf Plant Science Company Gmbh Method of increasing resistance against soybean rust in transgenic plants by increasing the scopoletin content
JP6719174B2 (ja) 2015-02-23 2020-07-08 住友ゴム工業株式会社 特定のプロモーター及び特定の蛋白質をコードする遺伝子を含むベクター、該ベクターが導入された形質転換植物、並びに、該ベクターを植物に導入することにより、ポリイソプレノイドの生産量を向上させる方法
JP6557990B2 (ja) 2015-02-23 2019-08-14 住友ゴム工業株式会社 特定のプロモーター及び特定の蛋白質をコードする遺伝子を含むベクター、該ベクターが導入された形質転換植物、並びに、該ベクターを植物に導入することにより、ポリイソプレノイドの生産量を向上させる方法
JP6557989B2 (ja) 2015-02-23 2019-08-14 住友ゴム工業株式会社 特定のプロモーター及び特定の蛋白質をコードする遺伝子を含むベクター、該ベクターが導入された形質転換植物、並びに、該ベクターを植物に導入することにより、ポリイソプレノイドの生産量を向上させる方法
CA2996806A1 (en) 2015-09-04 2017-03-09 Keygene N.V. Diplospory gene
EP3054014A3 (en) 2016-05-10 2016-11-23 BASF Plant Science Company GmbH Use of a fungicide on transgenic plants
WO2017223055A1 (en) 2016-06-20 2017-12-28 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College A green alga bicarbonate transporter and uses thereof
WO2018131586A1 (ja) 2017-01-10 2018-07-19 国立大学法人山口大学 抗ｇｐｃ３抗体
US11377662B2 (en) 2018-01-10 2022-07-05 Wisconsin Alumni Research Foundation Agrobacterium-mediated and particle bombardment transformation method for cowpea and dry bean meristem explants
AR118786A1 (es) 2018-08-13 2021-11-03 Univ Aarhus Plantas alteradas genéticamente que expresan receptores heterólogos que reconocen lipoquitooligosacáridos
AR118785A1 (es) 2018-08-13 2021-11-03 Univ Aarhus RECEPTORES DE LysM GENÉTICAMENTE ALTERADOS CON ESPECIFICIDAD Y AFINIDAD AGONISTAS ALTERADAS
WO2020067541A1 (ja) 2018-09-28 2020-04-02 協和キリン株式会社 抗体組成物
KR20210138563A (ko) 2018-12-06 2021-11-19 바게닝겐 유니버시테이트 식물 nin-유전자를 사이토킨에 반응성이 되도록 유전적으로 변경시키는 방법
AU2020244191A1 (en) 2019-03-21 2021-09-30 University Of Essex Enterprises Limited Methods of enhancing biomass in a plant through stimulation of RubP regeneration and electron transport
CN113874388A (zh) 2019-05-29 2021-12-31 主基因有限公司 孤雌生殖基因
JP2020195326A (ja) 2019-06-03 2020-12-10 住友ゴム工業株式会社 天然ゴムの製造方法、形質転換植物、空気入りタイヤの製造方法及びゴム製品の製造方法
GB201911068D0 (en) 2019-08-02 2019-09-18 Univ Edinburgh Modified higher plants
WO2021025962A1 (en) 2019-08-02 2021-02-11 Princeton University Rubisco-binding protein motifs and uses thereof
CN114727583A (zh) 2019-08-19 2022-07-08 奥尔胡斯大学 用于识别和结构化微生物群系的修饰外泌多糖受体
JP2021080204A (ja) 2019-11-19 2021-05-27 住友ゴム工業株式会社 融合タンパク質、物質製造方法、ベクター、形質転換細胞、空気入りタイヤの製造方法及びゴム製品の製造方法
WO2021170794A1 (en) 2020-02-28 2021-09-02 Cambridge Enterprise Limited Methods, plants and compositions for overcoming nutrient suppression of mycorrhizal symbiosis
WO2021177074A1 (ja) 2020-03-05 2021-09-10 住友ゴム工業株式会社 ポリイソプレノイドの製造方法、ベクター、形質転換植物、空気入りタイヤの製造方法及びゴム製品の製造方法
EP4130270A1 (en) 2020-04-01 2023-02-08 Kyowa Kirin Co., Ltd. Antibody composition
EP4153731A1 (en) 2020-05-19 2023-03-29 Aarhus Universitet Lysm receptor motifs
AU2021363100A1 (en) 2020-10-13 2023-05-25 Keygene N.V. Modified promoter of a parthenogenesis gene
CA3219711A1 (en) 2021-05-26 2022-12-01 Stephen P. Long C4 plants with increased photosynthetic efficiency
JP2023040705A (ja) 2021-09-10 2023-03-23 住友ゴム工業株式会社 トランス型ポリイソプレノイドの製造方法、ベクター、形質転換生物、空気入りタイヤの製造方法及びゴム製品の製造方法
JP2023127868A (ja) 2022-03-02 2023-09-14 住友ゴム工業株式会社 変異シス型プレニルトランスフェラーゼ（ｃｐｔ）ファミリー蛋白質、ポリイソプレノイドの製造方法、ベクター、形質転換植物、空気入りタイヤの製造方法及びゴム製品の製造方法
JP2023127870A (ja) 2022-03-02 2023-09-14 住友ゴム工業株式会社 変異シス型プレニルトランスフェラーゼ（ｃｐｔ）ファミリー蛋白質、ポリイソプレノイドの製造方法、ベクター、形質転換植物、空気入りタイヤの製造方法及びゴム製品の製造方法
JP2023127869A (ja) 2022-03-02 2023-09-14 住友ゴム工業株式会社 変異シス型プレニルトランスフェラーゼ（ｃｐｔ）ファミリー蛋白質、ポリイソプレノイドの製造方法、ベクター、形質転換植物、空気入りタイヤの製造方法及びゴム製品の製造方法
US20230323480A1 (en) 2022-04-11 2023-10-12 The Regents Of The University Of California Methods of screening for plant gain of function mutations and compositions therefor
US20240200085A1 (en) 2022-12-15 2024-06-20 Aarhus Universitet Synthetic activation of multimeric transmembrane receptors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0160692A1 (en) * 1983-11-03 1985-11-13 DE WET, Johannes Martenis Jacob Method for the transfer of exogenous genes in plants using pollen as a vector
DE3588230D1 (de) * 1984-05-11 2001-09-13 Syngenta Participations Ag Transformation von Pflanzenerbgut
WO1986005516A1 (en) * 1985-03-21 1986-09-25 Duke University Parasite-derived resistance
JPS63123325A (ja) * 1986-08-14 1988-05-27 マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エ−・ファウ トランスジェニック単子葉植物、その種子および植物の調製方法
EP0267159A3 (de) * 1986-11-07 1990-05-02 Ciba-Geigy Ag Verfahren zur genetischen Modifikation monokotyler Pflanzen
US5015580A (en) * 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
IL82153A (en) * 1987-04-09 1991-12-15 Yissum Res Dev Co Process for introducing genes into plants

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BR8706531A (pt) 1988-07-12
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AU8186387A (en) 1988-06-09
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