AR118785A1 - RECEPTORES DE LysM GENÉTICAMENTE ALTERADOS CON ESPECIFICIDAD Y AFINIDAD AGONISTAS ALTERADAS - Google Patents

RECEPTORES DE LysM GENÉTICAMENTE ALTERADOS CON ESPECIFICIDAD Y AFINIDAD AGONISTAS ALTERADAS

Info

Publication number
AR118785A1
AR118785A1 ARP190102305A ARP190102305A AR118785A1 AR 118785 A1 AR118785 A1 AR 118785A1 AR P190102305 A ARP190102305 A AR P190102305A AR P190102305 A ARP190102305 A AR P190102305A AR 118785 A1 AR118785 A1 AR 118785A1
Authority
AR
Argentina
Prior art keywords
lysm
altered
affinity
lco
genetically
Prior art date
Application number
ARP190102305A
Other languages
English (en)
Inventor
Jens Stougaard
Simon Boje Hansen
Lene Heegaard Madsen
Zoltan Bozsoki
Simona Radutoiu
Kira Gysel
Kasper Rjkjr Andersen
Original Assignee
Univ Aarhus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Aarhus filed Critical Univ Aarhus
Publication of AR118785A1 publication Critical patent/AR118785A1/es

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/30—Drug targeting using structural data; Docking or binding prediction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

Los aspectos de la presente revelación se refieren a receptores de LysM genéticamente alterados. En particular, la presente revelación se refiere a un parche hidrofóbico en el dominio LysM2 que puede incrementar la afinidad y/o la selectividad por LCO y por reemplazo de regiones en el dominio LysM1 con las correspondientes regiones del dominio LysM1 de un receptor de LysM donante que puede alterar la afinidad y/o la selectividad por el oligosacárido en particular para LCO y puede alterar la especificidad entre LCO cuando se usan regiones de una alta afinidad y especificidad por el receptor de LCO LysM como un receptor de NFR1 de legumbres. La presente revelación también se refiere a la alteración genética de receptores de LysM en plantas para incluir un parche hidrofóbico o alterar el parche hidrofóbico y alterar genéticamente los receptores de LysM en plantas por reemplazo de regiones en el dominio LysM2.
ARP190102305A 2018-08-13 2019-08-13 RECEPTORES DE LysM GENÉTICAMENTE ALTERADOS CON ESPECIFICIDAD Y AFINIDAD AGONISTAS ALTERADAS AR118785A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862718282P 2018-08-13 2018-08-13

Publications (1)

Publication Number Publication Date
AR118785A1 true AR118785A1 (es) 2021-11-03

Family

ID=67847677

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP190102305A AR118785A1 (es) 2018-08-13 2019-08-13 RECEPTORES DE LysM GENÉTICAMENTE ALTERADOS CON ESPECIFICIDAD Y AFINIDAD AGONISTAS ALTERADAS

Country Status (7)

Country Link
US (1) US20210233608A1 (es)
EP (1) EP3837357A1 (es)
CN (1) CN113166736A (es)
AR (1) AR118785A1 (es)
AU (1) AU2019321983A1 (es)
CA (1) CA3109236A1 (es)
WO (1) WO2020035488A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116323952A (zh) * 2020-05-19 2023-06-23 奥尔胡斯大学 Lysm受体基序

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4407956A (en) 1981-03-13 1983-10-04 The Regents Of The University Of California Cloned cauliflower mosaic virus DNA as a plant vehicle
CA1192510A (en) 1981-05-27 1985-08-27 Lawrence E. Pelcher Rna plant virus vector or portion thereof, a method of construction thereof, and a method of producing a gene derived product therefrom
NL8200523A (nl) 1982-02-11 1983-09-01 Univ Leiden Werkwijze voor het in vitro transformeren van planteprotoplasten met plasmide-dna.
US4536475A (en) 1982-10-05 1985-08-20 Phytogen Plant vector
EP0116718B2 (en) 1983-01-13 1996-05-08 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Process for the introduction of expressible genes into plant cell genomes and agrobacterium strains carrying hybrid Ti plasmid vectors useful for this process
EP0131623B2 (en) 1983-01-17 1999-07-28 Monsanto Company Chimeric genes suitable for expression in plant cells
WO1985001856A1 (en) 1983-11-03 1985-05-09 Johannes Martenis Jacob De Wet Method for the transfer of exogenous genes in plants using pollen as a vector
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4615807A (en) 1985-07-23 1986-10-07 United States Environmental Resources, Corp. Method for wastewater treatment
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
EP0242236B2 (en) 1986-03-11 1996-08-21 Plant Genetic Systems N.V. Plant cells resistant to glutamine synthetase inhibitors, made by genetic engineering
EP0265556A1 (en) 1986-10-31 1988-05-04 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Stable binary agrobacterium vectors and their use
IL84459A (en) 1986-12-05 1993-07-08 Agracetus Apparatus and method for the injection of carrier particles carrying genetic material into living cells
ATE225853T1 (de) 1990-04-12 2002-10-15 Syngenta Participations Ag Gewebe-spezifische promotoren
WO1992009696A1 (en) 1990-11-23 1992-06-11 Plant Genetic Systems, N.V. Process for transforming monocotyledonous plants
US5679558A (en) 1992-04-15 1997-10-21 Plant Genetic Systems, N.V. Transformation of monocot cells
US5633363A (en) 1994-06-03 1997-05-27 Iowa State University, Research Foundation In Root preferential promoter
NZ291734A (en) 1994-08-30 1997-09-22 Commw Scient Ind Res Org Plant transcription regulators from circovirus; isolated nucleic acid molecules and transgenic plants
CA2258565C (en) 1996-06-20 2011-11-22 The Scripps Research Institute Cassava vein mosaic virus promoters and uses thereof
EP0900279B1 (en) 1997-02-20 2004-09-29 Bayer BioScience N.V. Improved transformation method for plants
JP2002534129A (ja) 1999-01-14 2002-10-15 モンサント テクノロジー エルエルシー ダイズ形質転換方法
BR0010749B1 (pt) 1999-05-19 2013-09-03 processo aperfeiÇoado para transformaÇço de algodço mediada por agrobacterium
CA2430617A1 (en) 2000-12-04 2002-06-13 Universiteit Utrecht A novel root specific promoter driving the expression of a novel lrr receptor-like kinase
AU2004253987B2 (en) * 2003-07-03 2007-01-18 Jens Stougaard Jensen Nod-factor perception
CN101378651B (zh) 2005-12-23 2012-03-14 阿凯迪亚生物科学公司 氮源高效利用的单子叶植物
US20130305398A1 (en) * 2012-02-16 2013-11-14 Marie Coffin Genes and uses for plant enhacement
US8604274B2 (en) 2007-07-27 2013-12-10 Cropdesign N.V. Plants having enhanced yield-related traits and a method for making the same
FR2994793A1 (fr) * 2012-08-30 2014-03-07 Agronomique Inst Nat Rech Utilisation d'un recepteur kinase a motifs lysm pour ameliorer la reponse des plantes aux lipochitooligosaccharides.
AR105982A1 (es) * 2015-09-11 2017-11-29 Novozymes Bioag As Composiciones estables de inoculantes y métodos para producirlas
WO2020035486A1 (en) * 2018-08-13 2020-02-20 Aarhus Universitet Genetically altered plants expressing heterologous receptors that recognize lipo-chitooligosaccharides

Also Published As

Publication number Publication date
WO2020035488A1 (en) 2020-02-20
CN113166736A (zh) 2021-07-23
CA3109236A1 (en) 2020-02-20
EP3837357A1 (en) 2021-06-23
AU2019321983A1 (en) 2021-03-11
US20210233608A1 (en) 2021-07-29

Similar Documents

Publication Publication Date Title
CL2018003406A1 (es) Agonista del receptor de glucocorticoides e inmunoconjugados del mismo.
CO2017001573A2 (es) Receptor quimérico de antígeno anti-cd123
CL2016000060A1 (es) Derivados piperidinil indol y su uso como inhibidores factor de complemento b.
CO2017000510A2 (es) Constructos de car
CL2015002546A1 (es) Derivados 3-fenilpropilamina sustituidos para el tratamiento de enfermedades y trastornos oftálmicos
BR112018017172A2 (pt) anticorpos monoclonais anti-alfa-sinucleína para prevenção da agregação de tau
CL2019002314A1 (es) Compuestos moduladores del receptor de hidrocarburos de arilo (ahr).
CL2019001129A1 (es) Compuestos del péptido tirosina tirosina cíclico con anticuerpo acoplado como moduladores de receptores de neuropéptido y.
CL2020001452A1 (es) Agonista del receptor de glucocorticoides e inmunoconjugados de este.
CO2019007881A2 (es) Compuestos moduladores del receptor de hidrocarburos de arilo (ahr)
UY37351A (es) Complemento para el pienso
CO2019007882A2 (es) Compuestos moduladores del receptor de hidrocarburos de arilo (ahr)
BR112019014963A8 (pt) Compostos-bis para dispositivos opticamente ativos
CO2017005624A2 (es) Composiciones oftálmicas estabilizadas de omega 3
CO2020002576A2 (es) Compuestos de indazol como potenciadores alostericos mglur4, composiciones y métodos de tratamiento de la disfunción neurológica
PE20161509A1 (es) Sistemas, metodos y kits de limpieza de una region ocular
ECSP21001786A (es) Degradadores selectivos del receptor de estrógeno
BR112019008048A2 (pt) método para preparar rebaudiosídeo n com o uso de método enzimático
EA202090732A1 (ru) Составы для трансдермального введения
CL2012002612A1 (es) Compuestos derivados de benciloxicicloalquiladenosina, como agonistas selectivos de receptores de adenosina a1; composicion farmaceutica oftalmica; y su uso para el tratamiento de una afeccion seleccionada entre presion intraocular elevada, hipertension ocular o glaucoma.
AR118785A1 (es) RECEPTORES DE LysM GENÉTICAMENTE ALTERADOS CON ESPECIFICIDAD Y AFINIDAD AGONISTAS ALTERADAS
CL2017002967A1 (es) Beta-caseinas a2 y capacidad antioxidante.
CO2020008886A2 (es) Métodos para el procesamiento de materias primas de hidrocarburos
CL2020000305A1 (es) Novedosos compuestos que activan la ruta nrf2.
AR108775A1 (es) Composiciones y métodos para aumentar rendimiento de plantas y mejorar la resistencia a plagas