IL95800A - Biotin-labelled DNA by polymerase chain reaction and detection thereof - Google Patents

Biotin-labelled DNA by polymerase chain reaction and detection thereof

Info

Publication number
IL95800A
IL95800A IL9580090A IL9580090A IL95800A IL 95800 A IL95800 A IL 95800A IL 9580090 A IL9580090 A IL 9580090A IL 9580090 A IL9580090 A IL 9580090A IL 95800 A IL95800 A IL 95800A
Authority
IL
Israel
Prior art keywords
primers
hybridization
nucleic acid
capture
capture probe
Prior art date
Application number
IL9580090A
Other languages
English (en)
Other versions
IL95800A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL95800A0 publication Critical patent/IL95800A0/xx
Publication of IL95800A publication Critical patent/IL95800A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Transplanting Machines (AREA)
IL9580090A 1989-09-29 1990-09-26 Biotin-labelled DNA by polymerase chain reaction and detection thereof IL95800A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/414,542 US5232829A (en) 1989-09-29 1989-09-29 Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes

Publications (2)

Publication Number Publication Date
IL95800A0 IL95800A0 (en) 1991-06-30
IL95800A true IL95800A (en) 1994-10-07

Family

ID=23641905

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9580090A IL95800A (en) 1989-09-29 1990-09-26 Biotin-labelled DNA by polymerase chain reaction and detection thereof

Country Status (14)

Country Link
US (1) US5232829A (de)
EP (2) EP0420260B1 (de)
JP (1) JP2719225B2 (de)
AT (2) ATE187499T1 (de)
AU (2) AU6329090A (de)
BR (1) BR9004881A (de)
CA (1) CA2026280C (de)
DE (2) DE69034232T2 (de)
DK (2) DK0875583T3 (de)
ES (2) ES2140372T3 (de)
IL (1) IL95800A (de)
NO (1) NO302204B1 (de)
NZ (2) NZ235463A (de)
ZA (1) ZA907706B (de)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4038804A1 (de) 1990-10-09 1992-04-16 Boehringer Mannheim Gmbh Verfahren zur genus- oder/und spezies-spezifischen detektion von bakterien in einer probenfluessigkeit
US5753433A (en) * 1909-12-05 1998-05-19 Boehringer Mannheim Gmbh Method for the sensitive detection of nucleic acids
US5714380A (en) * 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
US5750338A (en) * 1986-10-23 1998-05-12 Amoco Corporation Target and background capture methods with amplification for affinity assays
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US6406844B1 (en) 1989-06-07 2002-06-18 Affymetrix, Inc. Very large scale immobilized polymer synthesis
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US6309822B1 (en) 1989-06-07 2001-10-30 Affymetrix, Inc. Method for comparing copy number of nucleic acid sequences
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US6379895B1 (en) 1989-06-07 2002-04-30 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
US6346413B1 (en) 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
US5547839A (en) 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US6551784B2 (en) 1989-06-07 2003-04-22 Affymetrix Inc Method of comparing nucleic acid sequences
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5232829A (en) * 1989-09-29 1993-08-03 Hoffmann-La Roche Inc. Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes
US6506558B1 (en) 1990-03-07 2003-01-14 Affymetrix Inc. Very large scale immobilized polymer synthesis
IT1248685B (it) * 1990-06-04 1995-01-26 Tecnogen Scpa Procedimento per la identificazione di sequenze polinucleotidiche e dispositivo relativo
FR2663040B1 (fr) * 1990-06-11 1995-09-15 Bio Merieux Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich.
US5695926A (en) * 1990-06-11 1997-12-09 Bio Merieux Sandwich hybridization assays using very short capture probes noncovalently bound to a hydrophobic support
JPH0499500A (ja) * 1990-08-17 1992-03-31 Kikkoman Corp アビジンまたはアビジン標識体の定量法およびビオチンまたはビオチン標識体の定量法
US5635348A (en) * 1990-10-05 1997-06-03 Hoffmann-La Roche Inc. Method and probes for identifying bacteria found in blood
NZ240079A (en) * 1990-10-09 1993-07-27 Boehringer Mannheim Gmbh Method for the detection of a nucleic acid or part thereof
WO1992008808A1 (en) * 1990-11-14 1992-05-29 Siska Diagnostics, Inc. Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor
WO1992010588A1 (en) 1990-12-06 1992-06-25 Affymax Technologies N.V. Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
FR2679255B1 (fr) * 1991-07-17 1993-10-22 Bio Merieux Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation.
EP0672173B1 (de) * 1991-11-01 2002-08-28 Diatech Pty. Ltd. Feststoff-phase erweiterungsverfahren
US6468740B1 (en) 1992-11-05 2002-10-22 Affymetrix, Inc. Cyclic and substituted immobilized molecular synthesis
US6943034B1 (en) 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
ATE293011T1 (de) * 1991-11-22 2005-04-15 Affymetrix Inc A Delaware Corp Kombinatorische strategien für die polymersynthese
AU2844792A (en) * 1991-12-11 1993-06-17 Becton Dickinson & Company Probes to chlamydia trachomatis
JPH07502414A (ja) * 1991-12-23 1995-03-16 バイエル　コーポレイション 溶液相サンドイッチハイブリダイゼーションアッセイに用いるためのクラミジアプローブ
CA2128891A1 (en) * 1992-01-29 1993-08-05 Cylia Keller Polynucleotide immobilized support
WO1993020234A1 (en) * 1992-03-31 1993-10-14 E.I. Du Pont De Nemours And Company A rapid, high capacity nucleic acid based assay
DE4212555A1 (de) * 1992-04-15 1993-10-21 Boehringer Mannheim Gmbh Verfahren zum Nachweis von Nukleinsäuren
WO1994002634A1 (en) * 1992-07-24 1994-02-03 University Of South Australia Amplification and detection process
JPH08503606A (ja) * 1992-10-09 1996-04-23 アモコ・コーポレーション 検定法
US5545528A (en) * 1993-04-15 1996-08-13 Hitachi Chemical Research Center Rapid screening method of gene amplification products in polypropylene plates
AU6945694A (en) * 1993-05-06 1994-12-12 Dade International Inc. Human papillomavirus detection assay
US5550040A (en) * 1993-06-23 1996-08-27 Hoffman-La Roche Inc. Method, reagents and kits for the detection of Neisseria gonorrhoeae
WO1995006753A1 (en) * 1993-09-03 1995-03-09 The United States of America, represented by The Secretary, Department of Health & Human Services Method and compositions for primer specific solid-phase detection of pcr products
US5601978A (en) * 1993-09-03 1997-02-11 Abbott Laboratories Oligonucleotides and methods for the detection of chlamydia trachomatis
FR2716263B1 (fr) 1994-02-11 1997-01-17 Pasteur Institut Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon.
US5480783A (en) * 1994-03-31 1996-01-02 The Perkin-Elmer Corporation Method for reducing background signals in DNA replication/detection assays
US6037127A (en) * 1994-03-31 2000-03-14 E. I. Du Pont De Nemours And Company Method for detection of non-denatured nucleic acid fragments
US5547861A (en) 1994-04-18 1996-08-20 Becton, Dickinson And Company Detection of nucleic acid amplification
US7378236B1 (en) 1994-06-17 2008-05-27 The Board Of Trustees Of The Leland Stanford Junior University Method for analyzing gene expression patterns
US7323298B1 (en) 1994-06-17 2008-01-29 The Board Of Trustees Of The Leland Stanford Junior University Microarray for determining the relative abundances of polynuceotide sequences
US20030026782A1 (en) * 1995-02-07 2003-02-06 Arthur M. Krieg Immunomodulatory oligonucleotides
ES2165402T3 (es) * 1994-07-16 2002-03-16 Roche Diagnostics Gmbh Procedimiento para la deteccion sensible de acidos nucleicos.
US5514551A (en) * 1994-10-14 1996-05-07 Gen-Probe Incorporated Compositions for the detection of Chlamydia trachomatis
US8236493B2 (en) 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
CA2163393C (en) * 1994-11-30 2003-04-22 Colleen Marie Nycz Amplification and detection of mycobacteria nucleic acids
US6022689A (en) * 1995-04-07 2000-02-08 University Of New Mexico Situ hybridization slide processes
US5989813A (en) * 1995-07-13 1999-11-23 Molecular Innovations, Inc. Detection of amplified nucleic acid sequences using bifunctional haptenization and dyed microparticles
US6027879A (en) * 1995-08-09 2000-02-22 The Regents Of The University Of California Detection and isolation of nucleic acid sequences using a bifunctional hybridization probe
US5800989A (en) * 1995-11-15 1998-09-01 Becton, Dickinson And Company Method for detection of nucleic acid targets by amplification and fluorescence polarization
EP0880598A4 (de) 1996-01-23 2005-02-23 Affymetrix Inc Verfahren zur analyse von nukleinsäure
US5814490A (en) * 1996-06-11 1998-09-29 Becton, Dickinson And Company Amplification and detection of chlamydia trachomatis nucleic acids
AU4151697A (en) * 1996-08-14 1998-03-06 Vanderbilt University Compositions of antichlamydial agents for the diagnosis and management of infection caused by (chlamydia)
EP0952228A3 (de) * 1996-09-24 1999-12-15 Rapigene, Inc. Zusammensetzungen und Verfahren zur Verbesserung der Hybridisierungsspezifität
WO1998013527A2 (en) * 1996-09-24 1998-04-02 Rapigene, Inc. Compositions and methods for enhancing hybridization specificity
US6361940B1 (en) 1996-09-24 2002-03-26 Qiagen Genomics, Inc. Compositions and methods for enhancing hybridization and priming specificity
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US6391655B1 (en) 1997-07-30 2002-05-21 Corning Incorporated Oxidized styrenic polymers for DNA binding
US6096501A (en) * 1997-11-04 2000-08-01 Becton Dickinson And Company Assay for Chlamydia trachomatis by amplification and detection of Chlamydia trachomatis crytpic plasmid
DE19811732A1 (de) * 1998-03-18 1999-09-30 November Ag Molekulare Medizin Mikrotiterplatte und Verfahren zum Nachweis von Biomolekülen
US6261769B1 (en) 1998-03-31 2001-07-17 The United States Of America As Represented By The Secretary Of Agriculture Intergenic spacer target sequence for detecting and distinguishing Chlamydial species or strains
DE19824900B4 (de) * 1998-06-04 2006-05-04 Roche Diagnostics Gmbh DNA-Nachweis über einen Strangreassoziationskomplex
US6545264B1 (en) 1998-10-30 2003-04-08 Affymetrix, Inc. Systems and methods for high performance scanning
DE19916929A1 (de) * 1999-04-15 2000-10-19 Bayer Ag Ein automatisierbarer Schnelltest zum Nachweis von Krebserkrankungen auf der Basis von Telomerase(hTC) mRNA mit spezifischen Primern und Sonden
US6248537B1 (en) 1999-05-28 2001-06-19 Institut Pasteur Use of the combing process for the identification of DNA origins of replication
FR2803913B1 (fr) 2000-01-13 2002-08-16 Pasteur Sanofi Diagnostics Procede d'immobilisation de reactif(s) affin(s) sur phase solide hydrophobe
CA2399733C (en) * 2000-02-07 2011-09-20 Illumina, Inc. Nucleic acid detection methods using universal priming
US7611869B2 (en) 2000-02-07 2009-11-03 Illumina, Inc. Multiplexed methylation detection methods
US8076063B2 (en) 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7955794B2 (en) 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
EP1164201A1 (de) * 2000-06-14 2001-12-19 Facultés Universitaires Notre-Dame de la Paix Umgekehrter nachweis zur Identifizierung und/oder Quantifizierung von Nukleotid-Zielsequenzen mittels Biochips
GB0016836D0 (en) 2000-07-07 2000-08-30 Lee Helen Improved dipstick assays (1)
US6682889B1 (en) 2000-11-08 2004-01-27 Becton, Dickinson And Company Amplification and detection of organisms of the Chlamydiaceae family
JP2002176985A (ja) * 2000-12-14 2002-06-25 Hitachi Software Eng Co Ltd Ｐｃｒ増幅された塩基配列の検出方法及び検出キット
US20030104354A1 (en) * 2001-11-30 2003-06-05 Reliance Life Sciences Private Limited Method and device for the rapid clinical diagnosis of human cytomegalovirus (hCMV) infection in biological samples
CA2467814A1 (en) * 2001-12-03 2003-06-12 Illumina, Inc. Multiplexed methylation detection methods
KR100532664B1 (ko) * 2002-09-09 2005-12-02 주식회사 바이오메드랩 클라미디아 트라코마티스 탐지용 프로브, 이를 포함하는 클라미디아 트라코마티스 탐지용 키트, 및 이를 이용한 클라미디아 트라코마티스의 탐지방법
US7807802B2 (en) 2002-11-12 2010-10-05 Abbott Lab Polynucleotides for the amplification and detection of Chlamydia trachomatis and Neisseria gonorrhoeae
JP2004261017A (ja) * 2003-02-27 2004-09-24 Arkray Inc クラミジア・トラコマティスの検出方法およびそのためのキット
MXPA05010429A (es) 2003-03-31 2005-11-04 Hoffmann La Roche Composiciones y metodos para detectar ciertos flavivirus que incluyen miembros del serogrupo del virus de la encefalitis japonesa.
WO2004094986A2 (en) * 2003-04-16 2004-11-04 Handylab, Inc. System and method for electrochemical detection of biological compounds
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
US7338763B2 (en) 2004-06-02 2008-03-04 Eppendorf Array Technologies S.A. Method and kit for the detection and/or quantification of homologous nucleotide sequences on arrays
US20060134650A1 (en) * 2004-12-21 2006-06-22 Illumina, Inc. Methylation-sensitive restriction enzyme endonuclease method of whole genome methylation analysis
CA2647566C (en) 2006-03-29 2017-01-03 Merial Limited Vaccine against streptococci
US20090263869A1 (en) 2007-08-27 2009-10-22 Lei Xi Methods and Compositions for PCR
WO2009099037A1 (ja) 2008-02-08 2009-08-13 Wako Pure Chemical Industries, Ltd. クラミドフィラ・キャビエ検出用プライマー及びプローブ、並びにこれを用いたクラミドフィラ・キャビエの検出方法
CA2748822C (en) * 2009-01-06 2016-09-06 Qimin You Cross priming amplification of target nucleic acids
US9458513B2 (en) 2010-03-23 2016-10-04 Wako Pure Chemical Industries, Ltd. Primer and probe for detecting chlamydia trachomatis, and method for detecting chlamydia trachomatis using same
AT512416B1 (de) 2012-02-13 2013-10-15 Greiner Bio One Gmbh Anordnung und verfahren zum nachweis von mikroorganismen in einem kulturgefäss
EA028686B1 (ru) * 2014-11-14 2017-12-29 Общество с ограниченной ответственностью "ИнтерЛабСервис" Набор реагентов для выявления днк chlamydia trachomatis и его применение
CA3029682A1 (en) * 2016-06-30 2018-01-04 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
KR102206392B1 (ko) * 2017-05-08 2021-01-21 고려대학교 산학협력단 세포벽 결합 도메인 복합체를 통한 박테리아 병원체의 다중 검출
US10323272B1 (en) * 2018-01-31 2019-06-18 Enzo Biochem, Inc. Nucleic acid probes for in situ hybridization

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4154795A (en) * 1976-07-23 1979-05-15 Dynatech Holdings Limited Microtest plates
US4228237A (en) * 1978-09-21 1980-10-14 Calbiochem-Behring Corp. Methods for the detection and determination of ligands
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
US4725388A (en) * 1982-10-12 1988-02-16 Dynatech Laboratories, Inc. Non-fluorescent vessels for holding test samples in fluorescent assays
GB8311905D0 (en) * 1983-04-29 1983-06-02 Cox R A Isolation and detection of nucleotide sequence
FI71768C (fi) * 1984-02-17 1987-02-09 Orion Yhtymae Oy Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning.
GB8507706D0 (en) * 1985-03-25 1985-05-01 Genetics Int Inc Magnetic nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4797355A (en) * 1985-06-13 1989-01-10 Amgen Inc. Methods for attaching polynucleotides to supports
US4751177A (en) * 1985-06-13 1988-06-14 Amgen Methods and kits for performing nucleic acid hybridization assays
US4822731A (en) * 1986-01-09 1989-04-18 Cetus Corporation Process for labeling single-stranded nucleic acids and hybridizaiton probes
FI76119C (fi) * 1986-02-27 1988-09-09 Orion Yhtymae Oy Kvantitativ bestaemning av nukleinsyramolekyler och reagensfoerpackning som anvaends vid foerfarandet.
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
CA1301606C (en) * 1986-05-02 1992-05-26 David H. Gillespie Chaotropic method for evaluating nucleic acids in a biological sample
WO1988003957A1 (en) * 1986-11-24 1988-06-02 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
FR2607518B1 (fr) * 1986-12-01 1989-10-20 Transgene Sa Vecteur viral et adn recombinant codant pour la proteine p25 du virus agent causal du s.i.d.a., culture cellulaire infectee, proteine obtenue, vaccin et anticorps obtenus
AU622104B2 (en) * 1987-03-11 1992-04-02 Sangtec Molecular Diagnostics Ab Method of assaying of nucleic acids, a reagent combination and kit therefore
JPH07107537B2 (ja) * 1987-08-03 1995-11-15 イーストマン コダック カンパニー アビジン−及びビオチン−固定試薬，分析要素並びにその使用法
CA1339351C (en) * 1987-10-15 1997-08-26 Michael S. Urdea Nucleic acid multimers and amplified nucleic acid hybridization assays using same
IT1224253B (it) * 1988-04-08 1990-09-26 Sclavo Spa Oligonucleotidi sintetici utili per la determinazione di chlamydia trachomatis in un campione biologico
AU632494B2 (en) * 1988-05-20 1993-01-07 F. Hoffmann-La Roche Ag Immobilized sequence-specific probes
KR920700360A (ko) * 1989-03-22 1992-02-19 하리크 프리드리히 미끄럼 베어링
US5232829A (en) * 1989-09-29 1993-08-03 Hoffmann-La Roche Inc. Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes
CA2031659A1 (en) * 1990-01-26 1991-07-27 John B. Findlay Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods

Also Published As

Publication number Publication date
EP0420260A2 (de) 1991-04-03
EP0875583B1 (de) 2006-11-15
JPH03206898A (ja) 1991-09-10
ATE187499T1 (de) 1999-12-15
JP2719225B2 (ja) 1998-02-25
DK0420260T3 (da) 2000-03-27
NZ247522A (en) 1994-03-25
DE69034232D1 (de) 2006-12-28
ZA907706B (en) 1991-06-26
DE69033387T2 (de) 2000-03-30
EP0875583A2 (de) 1998-11-04
CA2026280C (en) 2003-04-15
NO904240L (no) 1991-04-02
DE69034232T2 (de) 2007-03-01
EP0420260B1 (de) 1999-12-08
NO302204B1 (no) 1998-02-02
NZ235463A (en) 1994-03-25
NO904240D0 (no) 1990-09-28
US5232829A (en) 1993-08-03
EP0875583A3 (de) 1999-02-17
ES2275292T3 (es) 2007-06-01
AU6329090A (en) 1991-04-11
AU7280494A (en) 1994-11-24
ATE345398T1 (de) 2006-12-15
IL95800A0 (en) 1991-06-30
CA2026280A1 (en) 1991-03-30
DE69033387D1 (de) 2000-01-13
AU685144B2 (en) 1998-01-15
ES2140372T3 (es) 2000-03-01
BR9004881A (pt) 1991-09-10
EP0420260A3 (en) 1991-09-18
DK0875583T3 (da) 2007-02-26

Similar Documents

Publication Publication Date Title
CA2026280C (en) Biotin-labelled dna by polymerase chain reaction and detection thereof
US20220251618A1 (en) Amplicon rescue multiplex polymerase chain reaction for amplification of multiple targets
EP0457824B1 (de) Nachweis einer nukleinsäuresequenz oder einer änderung darin
EP0359789B1 (de) Verstärkung und nachweis von nukleinsäuresequenzen
US5989817A (en) Target nucleic acid and capture method
US7951541B2 (en) Assay kit for use in method of detecting a target nucleic acid
EP0408918B1 (de) Verfahren zum Nachweis von Nucleinsäuren
AU5359690A (en) Polymerase chain reaction products incorporating reporter moieties and affinity seperation
AU723602B2 (en) Biotin-labelled DNA by polymerase chain reaction and detection thereof
JP3396218B2 (ja) 核酸検出方法
JPH03123500A (ja) 核酸の分別方法
JPH05236998A (ja) 核酸検出方法
JPH07284391A (ja) ヒトヘルペスウイルス検出用オリゴヌクレオチドおよびその用途
CA2012984A1 (en) Process for rapid nucleic acid detection by incorporating a reporter moiety into amplified target nucleic acid followed by affinity capture
JPH1014572A (ja) プローブライブラリーの製造方法、該製造方法により得られたプローブライブラリー、該プローブライブラリーから他のｄｎａまたはｒｎａとハイブリッドするプローブを精製する方法、及び該方法により精製したプローブ

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired